Department of Biomedical Sciences

Projects

Projects per year

2006 2025

• 1 Curtailed
• 7 Not started
• 126 Active
• 173 Finished

Projects per year

Search results

• MQRF21: Pre-clinical development and commercialization of a novel gene therapy for MND

  Rayner, S. & Chung, R.

  21/01/21 → 20/01/24

  Project: Research

• Targeting pathogenic TAR DNA-binding protein 43 to treat frontotemporal dementia and motor neuron disease

  Ke, Y., van Hummel, A., Ariawan, D., Ittner, L. & Martin, A.

  1/01/21 → 31/12/23

  Project: Research

• Microglia and the inflammation spectrum - not just good or bad

  Morsch, M., Lee, A. & Williams, K.

  1/01/21 → 31/12/23

  Project: Research

• Unravelling the molecular mechanism of tau spread in Alzheimer's disease

  Fath, T., Van Eersel, J., Przybyla, M. & Ittner, L.

  1/01/21 → 31/12/24

  Project: Research

• Single-session Introduction of Mutations in Parallel Lines (SIMPL)

  Ittner, L.

  1/01/21 → 31/12/23

  Project: Research

• Novel nanotechnology strategies for drug delivery to the brain and preclinical evaluation of therapies

  Shi, B.

  1/01/21 → 31/12/25

  Project: Research

• Cuffless Blood Pressure Project (AtCor top-up scholarship - James Cox)

  Butlin, M. & Cox, J.

  2/10/20 → 30/05/23

  Project: Research

• Development of a TDP43-targeting gene therapy for ALS

  Chung, R., Lisowski, L., Walker, A. K., Rogers, M., Lee, A., Morsch, M. & Rayner, S.

  1/10/20 → 30/09/23

  Project: Research

• Development of a dose-escalatable AAV delivery system for ALS gene therapies

  Chung, R., Lisowski, L. & Shi, B.

  1/10/20 → 30/09/22

  Project: Research

• Efficacy of aerosolised disinfectant to kill surface-associated Staphylococcus aureus on contact

  Vickery, K.

  9/09/20 → 30/09/20

  Project: Research

• Lighthouse II: A confirmatory, randomized, placebo-controlled, group-sequential trial to investigate the efficacy and safety of Triumeq in patients with Amyotrophic Lateral Sclerosis (ALS): The Lighthouse II Trial

  Gold, J., Van den Berg, L. & Chapman, N.

  21/08/20 → 31/12/22

  Project: Research

• The link between threat perception, action, and cardiovascular risk

  McMullan, S.

  1/07/20 → 30/06/21

  Project: Research

• Is it the same? How does hypothalamus produce hypertension in acquired and inherited kidney disease vs. essential hypertension

  Phillips, J. K. & Hildreth, C.

  1/07/20 → 31/12/21

  Project: Research

• CRC-P round 9: Manufacturing consortium for cancer radioimmunotherapy

  Groth, A., Chandler, C., Adams, T., Walsh, B., Lengkeek, N., Chung, R., Gurney, H., Gillatt, D. & O'Meara, T.

  1/07/20 → 30/06/23

  Project: Research

• Multimodal Application Of Liquid Biopsies In Melanoma

  Rizos, H.

  30/06/20 → 30/06/23

  Project: Research

• Biomarker-based identification of at-risk patients with COVID-19

  Guillemin, G. & Brew, B.

  1/06/20 → 31/12/21

  Project: Research

  File

• IDENTIFICATION OF NEW BIOMARKERS FOR SEVERITY, DISEASE PROGRESSION AND RESPONSE TO TREATMENT FOR COVID-19

  Guillemin, G.

  1/06/20 → 1/12/20

  Project: Research

  File

• The unexplored posttranslational modification (SUMOylation) of TDP-43 affects aggregate formation and localisation

  Morsch, M., Maurel, C., Lee, A., Vourc'H, P. & Chung, R.

  1/06/20 → 31/05/21

  Project: Research

• Clearance of TDP-43 by PROteolysis TArgeting Chimera (PROTAC) dual targeting to treat amyotrophic lateral sclerosis (ALS)

  Lee, A., Rayner, S., Martin, A., van Hummel, A., Morsch, M., Shi, B., Ke, Y., Ittner, L. & Chung, R.

  4/05/20 → 3/05/21

  Project: Research

• Collaborate and Cure: The Macquarie University Cancer Biobank

  Rizos, H.

  21/02/20 → 31/12/21

  Project: Research

• Novel mechanisms of neurodegeneration induced by dysfunctional actin dynamics in MND

  Atkin, J. & Fath, T.

  10/02/20 → 9/02/21

  Project: Research

• Comprehensive transcriptome analysis of neuroanatomical regions with variable pTDP-43 pathology in sporadic ALS patients

  Williams, K., Henden, L. & Blair, I.

  28/01/20 → 27/01/21

  Project: Other

• Medium-Chain Fatty Acids in Alzheimer's Disease Prevention

  Hillebrandt, H.

  6/01/20 → …

  Project: Research

• HSIS

  Shah, T.

  1/01/20 → 31/07/21

  Project: Research

• AU-ARROW: The AUstralian-Multidomain Approach to Reduce Dementia Risk by PrOtecting Brain Health With Lifestyle Intervention

  Shah, T., Botelho Dias, C. & Hillebrandt, H.

  1/01/20 → 31/12/22

  Project: Research

• CMNDR: Macquarie University Centre for Motor Neuron Disease Research

  Atkin, J., Blair, I., Rowe, D., Atkin, J., Chung, R., Guillemin, G., Laird, A., Lee, A., Morsch, M., Shi, B., Williams, K. & Yang, S.

  1/01/20 → 31/12/22

  Project: Other

• The AUstralian-Multidomain Approach to Reduce Dementia Risk by PrOtecting Brain Health With Lifestyle Intervention

  Fuller, S., Shah, T., Martins, R., Botelho Dias, C., Sohrabi, H., Chatterjee, P. & Hillebrandt, H.

  1/01/20 → 30/09/24

  Project: Research

• The kynurenine pathway in neuroinflammatory diseases: Translation to prognostics and therapeutics

  Guillemin, G.

  1/01/20 → 31/12/24

  Project: Other

• COAD-P002: Examine the Effects of CocoMCT® on Clinical Factors Related to Health, Cognition, Quality of Life and Alzheimer's Disease: Double-Blind, Randomized Controlled Feeding Interventional Trial

  Botelho Dias, C. & Hillebrandt, H.

  1/01/20 → 31/12/23

  Project: Research

• High Resolution PET-CT for Small Animal Molecular and Anatomical Imaging

  Meikle, S., Calamante, F., Balleine, B. W., Kassiou, M., Ittner, L., Vittorio, O., Gregoire, M., Goldys, E., Kuncic, Z., Codd, R. & Rozenfeld, A.

  1/01/20 → 31/12/20

  Project: Research

• Tackling Hospital Acquired Infections with Peptide Mimics

  Willcox, M. D. P., Kumar, N., Boyer, C., Wong, E., McKenzie, D., Suchowerska, N. & Vickery, K.

  1/01/20 → 31/12/23

  Project: Research

• Determining the molecular basis of amyotrophic lateral sclerosis

  Blair, I.

  1/01/20 → 31/12/24

  Project: Research

• Loss-of-function of site-specific tau phosphorylation in Alzheimer's disease

  Ittner, A.

  1/01/20 → 31/12/24

  Project: Other

• Mechanisms of memory function involving site-specific tau phosphorylation

  Ittner, A. & Ittner, L.

  1/01/20 → 31/12/23

  Project: Other

• JG Lang Travel Grant to support attendance at the International Symposium on ALS/MND in Perth 4-6 December 2019

  Wright, A.

  1/12/19 → 31/12/19

  Project: Research

• THE KYNURENINE PATHWAY IN NEUROINFLAMMATORY DISEASES: TRANSLATION TO PROGNOSTICS AND THERAPEUTICS

  Guillemin, G.

  30/11/19 → 29/11/24

  Project: Research

• Novel Nanotechnology strategy for drug delivery to in the brain and evaluation of preclinical therapies

  Shi, B.

  1/11/19 → 31/12/20

  Project: Other

• Disease susceptibility, precision medicine and ALS

  Atkin, J., Blair, I., Rowe, D. & Lim, E.

  30/09/19 → 30/09/21

  Project: Other

• Oncogenic Signaling in Uveal Melanoma

  Park, J. & Rizos, H.

  4/09/19 → 3/09/20

  Project: Research

• Refinement of CCNF gene therapy for MND

  Rayner, S., Lee, A. & Chung, R.

  1/08/19 → 30/06/20

  Project: Research

• Disease susceptibility, precision medicine and ALS

  Atkin, J. & Blair, I.

  1/07/19 → 1/07/21

  Project: Research

• Biobanks, Big Data and ME: establishing a global registry and biobank in Australia to drive discovery of blood biomarkers.

  Fisher, P., Nicholl, H., Gooley, P., Lidbury, B. A., Guillemin, G. & Josev, E.

  1/07/19 → 31/12/24

  Project: Research

• Proteomic and molecular investigations into the diagnosis and progression of Motor Neuron Disease by the identification of biomarkers found in plasma

  Suddull, H., Chung, R. & Lee, A.

  1/07/19 → 30/06/22

  Project: Research

• Does inflammation in the brain lead to hypertension in kidney disease?

  Phillips, J. K. & Hildreth, C.

  1/07/19 → 1/06/20

  Project: Research

• Is a hormone controlled by the brain driving high blood pressure in PKD?

  Hildreth, C., Phillips, J. K. & Goodchild, A.

  1/07/19 → 31/12/20

  Project: Research

• Investigating the role of large structural variation in MND by analysis of whole-genome sequencing data

  Fifita, J., Williams, K. & Blair, I.

  1/06/19 → 31/05/20

  Project: Research

• Targeting the nucleo-cytoplasmic transport machinery in sporadic and familial ALS

  Morsch, M., Lee, A., Walker, A. K. & Chung, R.

  1/06/19 → 31/05/20

  Project: Research

• The Michael Family Cancer Research Fund

  Rizos, H.

  27/05/19 → 31/12/21

  Project: Research

• SAX Institute and NSW Ministry of Health ($36,900) for a project entitled: ‘Biomedical engineering: a critical workforce in healthcare delivery

  Taksa, L., Hull, D., Guo, F., Kalfa, S., Appleyard, R. & Turner, D.

  23/05/19 → 27/09/19

  Project: Research

• Biomedical engineering workforce

  Taksa, L., Hull, D., Guo, F., Bowles, M., Kalfa, S., Appleyard, R., Turner, D., Paterson, W., Paterson, R. & Cousins, L.

  23/05/19 → 27/09/19

  Project: Research