Department of Biomedical Sciences

Projects

Projects per year

2006 2025

• 1 Curtailed
• 6 Not started
• 127 Active
• 173 Finished

Projects per year

Search results

• Testing drugs that induce autophagy for the treatment of Machado Joseph disease

  Laird, A., Nicholson, G. & Chung, R.

  1/03/17 → …

  Project: Research

• Transfer from ANZAC Institute - Establishment of a model phenotype suitable for Machado Joseph Disease (MJD) drug screening

  Laird, A.

  1/03/17 → …

  Project: Research

• New proteins and pathways contributing to TDP-43-mediated neurodegeneration

  Walker, A. K. & Atkin, J.

  17/02/17 → …

  Project: Research

• uPAR interference peptide (iPEP) antagonists of avß6·uPAR interaction as colorectal cancer (CRC) metastasis therapy leads

  Baker, M. S., Adhikari, S., Ahn, C. & Fanayan, S.

  1/02/17 → …

  Project: Research

• Blood based biomarkers of prognosis, treatment response and treatment resistance (liquid biopsies)

  Rizos, H.

  17/01/17 → …

  Project: Research

• Preventing motor neurone disease: barriers, facilitators, costs and benefits of genetic testing for MND in Australia

  Crook, A., Hogden, A., Mumford, V., Rowe, D., Blair, I. & Williams, K.

  1/01/17 → 31/12/17

  Project: Research

• The hunt for therapeutic modifiers of motor neuron disease: identifying aberrant DNA methylation profiles in patient blood and brain

  Williams, K. & Blair, I.

  1/01/17 → …

  Project: Research

• Blood biomarkers for the diagnosis of pre-clinical Alzheimer¿s disease employing the Dominantly Inherited Alzheimer Network cohort

  Molloy, M., Martins, R., Fagan, A., Wenk, M., Multhaup, G., Xiong, C. & Chatterjee, P.

  1/01/17 → …

  Project: Research

• Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

  Morsch, M. & Graeber, M.

  1/01/17 → 31/12/19

  Project: Research

• TotAL: A 56-Week, Double-Blind, Randomised Study to Evaluate the Efficacy of Testosterone, With and Without DHA Supplementation on Cerebral Amyloid Load in Known Brain Amyloid-PET Positive Men with Subjective Memory Complaints

  Botelho Dias, C. & Hillebrandt, H.

  1/01/17 → 31/12/21

  Project: Research

• Testing drugs for the treatment of Machado Joseph disease

  Laird, A., Shi, B., Cole, N., Ooi, L. & Nicholson, G.

  1/01/17 → …

  Project: Research

• A laser platform to undertake single-cell-resolution experiments in zebrafish

  Chung, R., Morsch, M., Laird, A. & Cole, N.

  1/01/17 → …

  Project: Research

• Advanced protein quantification capability

  Walker, A. K., Lee, A., Connor, M., Atkin, J., Lim, E., Baker, M. S., Rizos, H., Phillips, J. K., Yang, S. & Blair, I.

  1/01/17 → …

  Project: Research

• Slowing progression of Alzheimer's disease by modulating the kynurenine pathway

  Guillemin, G., Lovejoy, D., Ittner, A., Braidy, N., Doecke, J., Lim, E., Nicolazzo, J. & Ittner, L.

  1/01/17 → 31/12/19

  Project: Research

• Determinants of response to immune checkpoint inhibitors in melanoma

  Rizos, H., Long, G., Menzies, A. M., Yang, J., Carlino, M., Kefford, R., Scolyer, R., MQRES, M., MQRES 3 (International), M. 3. & De St Groth, B. F.

  1/01/17 → 31/12/20

  Project: Research

• Do polycystic kidney disease gene mutations affect the brain? Towards understanding their role in the development of central cardiovascular dysfunction

  Hildreth, C., Lee, A., Phillips, J. K. & Chung, R.

  1/01/17 → …

  Project: Research

• Bio-semi EEG system

  McAlpine, D., McMahon, C., Johnson, B., Sharma, M., Boisvert, I., Chung, R. & Martins, R.

  1/01/17 → …

  Project: Research

• Liquid Biopsy for Personalised Monitoring of Melanoma Patients

  Rizos, H., Ziman, M., Millward, M., Hayward, N. K., Amanuel, B., Gray, E., Khattak, M., Lo, J. & Beckhouse, A.

  1/01/17 → 31/12/19

  Project: Research

• Understanding the early disease mechanisms of motor neuron disease and frontotemporal dementia

  Walker, A. K., Bye, C., Halliday, G., Atkin, J., Molloy, M. & Lee, V.

  1/01/17 → …

  Project: Research

  • Frontotemporal Dementia
  • Motor Neuron Disease
  • Queensland

• Macquarie University Centre for Motor Neuron Disease Research

  Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, E., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A. K., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, M., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.

  1/01/17 → 31/12/19

  Project: Research

• Understanding the Pathogenesis of Sporadic and Familial Motor Neuron Disease Using Zebrafish

  Cole, N., Walker, A. K., Laird, A., Blair, I., Nicholson, G., Atkin, J., Chung, R., Guillemin, G., Rowe, D. & Morsch, M.

  1/01/17 → 31/12/17

  Project: Research

• Clinical trial of a suprachoroidal visual prosthesis for the profoundly vision impaired

  Fung, A., Suaning, G., Lovell, N., Grigg, J., daCruz, A. M., Morley, J. W., James, N., Tumuluri, K., Ayton, L. & McCluskey, P.

  1/01/17 → …

  Project: Research

• Acquired resistance to PD1 inhibition in melanoma

  Rizos, H., Carlino, M., Kefford, R., Zhang, X. D., Menzies, A. M., Long, G., McGuire, H., Yang, J., Scolyer, R. & De St Groth, B. F.

  1/01/17 → 31/12/21

  Project: Research

• Biomolecular Discovery and Design Research Centre

  Packer, N., Paulsen, I., Nevalainen, H., Haynes, P., Molloy, M., Atwell, B., Barron, A., Beggs, P., Bergquist, P. L., Brown, L., Cornish, J., Chung, R., De Deene, Y., Garcia-Bennett, A., Gillings, M., Goodchild, A., Guillemin, G., Hallinan, J., Hose, G., Jaschke, P., Mabbutt, B., Raftos, D., Ranganathan, S., Sofronov, G., Sunna, A., Tetu, S., Andersen, M., Willows, R., Ahn, C., Breen, E., Campbell, M., Care, A., Cordina, N., Curach, N., Everest Dass, A., Elbourne, L., Goold, H., Hassan, K., Kautto, L., Krisp, C., Kroukamp, H., Lee, A., Lin, C., Mackie, A., McKay, M., McQuade, L., Mirzaei, M., Mohamedali, A., Ostrowski, M., Parker, L., Pascovici, D., Penesyan, A., Shah, B., Sun, A., Thompson, E. & Williams, T.

  1/01/17 → …

  Project: Research

• A research assistant to build capacity in and use of Macquarie's bioreactor equipment: towards production and maintenance of live bioartificial tissues for sustainable scientific use

  Sen, I., Avolio, A., Gillatt, D., Zvyagin, A., De Deene, Y., Vickery, K., Fuerbach, A. & Parker, L.

  1/01/17 → …

  Project: Research

  • assistant

• Use of the EOS x-ray imaging system to measure knee and hip range of motion

  Turner, D.

  1/01/17 → …

  Project: Research

• Understanding how the brain causes high blood pressure in inherited kidney disease - the role of hormones

  Hildreth, C.

  1/01/17 → …

  Project: Research

• Generation of a stem cell model for the validation of novel amyotrophic lateral sclerosis (ALS) candidate genes.

  Yang, S. & Blair, I.

  1/01/17 → …

  Project: Research

• Light-controlled chemical sequestration of proteins for enhanced detection limits

  Liu, F., Ahn, C. & Mohamedali, A.

  1/01/17 → …

  Project: Research

• Central aortic blood pressure in children: establishing a gold standard non-invasive assessment of cardiovascular risk

  Avolio, A., Mynard, J., Cheung, M. & Smolich, J.

  1/01/17 → …

  Project: Research

• Computation simulation for cerebrovascular haemodynamics employing precision arterial wall mechanical properties

  Sen, I., Morgan, M. & Yang, L.

  1/01/17 → …

  Project: Research

• Understanding how diabetic foot infections develop and progress

  Hu, H., Malone, M. & Vickery, K.

  1/01/17 → …

  Project: Research

• Light, sound and touch influence the autonomic nervous system via a non-canonical pathway

  Goodchild, A., McMullan, S., Burke, P., Dampney, R. & Cornish, J.

  1/01/17 → 31/08/21

  Project: Research

• Unravelling the ability of a metabolic pathway to suppress normal immune system function in brain cancer

  Adams, S., Guillemin, G., McDonald, K., Teo, C., Zaunders, J., Jones, S., Sedger, L., Bustamante, S., Turner, J., Heng, B. & Sundaram, G.

  8/12/16 → …

  Project: Research

• Remote Ischemic Preconditioning (RIPC) Device

  Javadzadegan, A. & Moshfegh, A.

  1/12/16 → …

  Project: Research

  • Ischemic Preconditioning
  • Appointments and Schedules
  • Equipment and Supplies

• Radiation-induced markers for vascular targeting of brain AVM tissues.

  Zhao, Z. & Stoodley, M.

  24/10/16 → 23/10/17

  Project: Research

• The primitive startle reflex: implications for post traumatic stress disorders

  Goodchild, A. & McMullan, S.

  1/10/16 → …

  Project: Research

• 2016 Endeavour Research Fellowship (Golzan)

  Golzan, M.

  1/08/16 → 31/01/17

  Project: Research

• How kidney disease causes heart disease

  Phillips, J. K. & Hildreth, C.

  1/07/16 → …

  Project: Research

• Neuroinflammation in frontotemporal dementia: the role of microglia in TDP-43-related disease

  Walker, A. K., Guillemin, G., Atkin, J. & Lee, V.

  1/07/16 → …

  Project: Research

  • Frontotemporal Dementia
  • Microglia
  • Appointments and Schedules

• Technology platform for noninvasive measurements of intracranial pressure

  Avolio, A., Town, G., Graham, S. L., Stoodley, M., Sen, I., Golzan, M., Qasem, A. & MQRES, M.

  25/06/16 → …

  Project: Research

• New approaches to plasma biomarker studies in MND/ALS.

  Chung, R., Molloy, M., Rowe, D., Guillemin, G., Krisp, C. & Lee, A.

  10/06/16 → 9/06/17

  Project: Research

• To investigate the role of circulating tumour DNA in early and advanced melanoma.

  Lee, J. & Rizos, H.

  9/06/16 → 9/06/17

  Project: Research

• New directions for early diagnosis of MND: a large-scale longitudinal analysis of multiple biomarkers to find diagnostic and prognostic 'fingerprints'

  Guillemin, G., Rowe, D., Blair, I., Atkin, J., Lim, E., Lovejoy, D., Oytam, Y., Brew, B., Rodgers, K., Rogers, M., McCombe, P. A., Henderson, R. D., Woodruff, T., Ngo, S. & Tosolini, A.

  1/06/16 → 31/08/17

  Project: Research

  • Dermatoglyphics
  • Early Diagnosis
  • Appointments and Schedules
  • Biomarkers
  • Direction compound

• A systems biology capability for the Ramaciotti Centre for Genomics

  Packer, N., James, D., Simpson, S., Cordwell, S., Wilkins, M., Payne, R., Cavicchioli, R., Guillemin, G., Goodchild, A., Scott, R., Thorne, R., Hondermarck, H., Djordjevic, S., McDougald, D. & Myers, G.

  23/05/16 → 27/02/17

  Project: Research

• Identification of phenotypic modifiers in sporadic ALS through systems genomics

  Williams, K., Benyamin, B., Zhao, Q., Blair, I., Wray, N. & Rowe, D.

  9/05/16 → 8/05/17

  Project: Research

• Development new collaboration in vascular hemodynamics, and develop research projects in tissue engineering and regenerative medicine with international partners

  Sen, I.

  1/04/16 → 30/12/16

  Project: Research

• New nanoparticle strategies for efficient delivery and controlled release into the brain

  Shi, B.

  1/04/16 → 31/03/20

  Project: Research

• Next Generation Colorectal Cancer Biomarkers and Treatment

  Ahn, C.

  1/04/16 → …

  Project: Research

  • Tumor Biomarkers
  • Colorectal Neoplasms
  • Appointments and Schedules

• Does the transfer of ALS protein aggregates between motor neurons trigger neurodegeneration?

  Morsch, M., Chung, R., Cole, N., Yerbury, J. & Blair, I.

  1/04/16 → 31/03/17

  Project: Research