Department of Biomedical Sciences

Projects

Projects per year

2006 2025

• 1 Curtailed
• 5 Not started
• 128 Active
• 173 Finished

Projects per year

Search results

• Research

  Does inflammation in the brain lead to hypertension in kidney disease?

  Phillips, J. K. & Hildreth, C.

  1/07/19 → 1/06/20

  Project: Research

• How kidney disease rewires the brain to reduce heart health: changes to support cells in the brain

  Phillips, J. K. & Hildreth, C.

  3/07/17 → 2/07/19

  Project: Research

• A strongly adherent graphene coating on platinum electrodes for cochlear implants

  Liu, Y., Shi, B. & Lawson, T.

  6/01/16 → 29/02/16

  Project: Research

• Understanding factors involved in the development of hypertension

  McMullan, S., Allen, A., Fong, A. & Menuet, C.

  1/01/16 → 31/08/19

  Project: Research

• Blood based biomarkers of prognosis, treatment response and treatment resistance (liquid biopsies)

  Rizos, H.

  17/01/17 → …

  Project: Research

• Does the transfer of ALS protein aggregates between motor neurons trigger neurodegeneration?

  Morsch, M., Chung, R., Cole, N., Yerbury, J. & Blair, I.

  1/04/16 → 31/03/17

  Project: Research

• Elucidating the Pathogenesis of Sporadic Motor Neurone Disease Using Zebrafish Models

  Cole, N., Nicholson, G. & Walker, A.

  11/03/16 → 10/03/17

  Project: Research

• Developing a model of the newly discovered and most common form of genetically inherited form of human Motor Neurone Disease (MND), C9ORF72, using zebrafish

  Cole, N.

  22/10/14 → 30/06/16

  Project: Research

• Developing a new gene therapy approach to protect against glaucoma damage

  Gupta, V., Graham, S. L. & You, Y.

  1/01/15 → 31/12/16

  Project: Research

  • gene therapy
  • damages

• Light-controlled chemical sequestration of proteins for enhanced detection limits

  Liu, F., Ahn, C. & Mohamedali, A.

  1/01/17 → …

  Project: Research

• New directions for early diagnosis of MND: a large-scale longitudinal analysis of multiple biomarkers to find diagnostic and prognostic "fingerprints"

  Guillemin, G., Rowe, D., Blair, I., Atkin, J., Zetterberg, H., Rogers, M., Lovejoy, D., Lim, E. & Tan, V.

  1/01/18 → 31/12/18

  Project: Research

• SAX Institute and NSW Ministry of Health ($36,900) for a project entitled: ‘Biomedical engineering: a critical workforce in healthcare delivery

  Taksa, L., Hull, D., Guo, F., Kalfa, S., Appleyard, R. & Turner, D.

  23/05/19 → 27/09/19

  Project: Research

• Molecular Devices Flexstation 3 Instrument & 16 Channel Pipetter Head Package

  Phillips, J. K., Connor, M., Guillemin, G., Lim, E., Rizos, H., Chung, R., McMorran, B., Lovejoy, D. & Zvyagin, A.

  1/01/14 → 31/12/14

  Project: Research

• A urinary biomarker to track progression of ALS in humans

  Guillemin, G., Rogers, M., Benatar, M., Schultz, D. & Chataway, T.

  1/08/14 → 31/07/16

  Project: Research

• "Re-educating" immune cells as a combination therapy to limit breast cancer metastasis

  Heng, B. & Guillemin, G.

  1/01/16 → 1/01/17

  Project: Research

• New inhibitors of kynurenine-3-monooxygenase for Alzheimer's disease therapy

  Guillemin, G. & Lovejoy, D.

  15/06/15 → 30/04/17

  Project: Research

  • Kynurenine 3-Monooxygenase
  • Appointments and Schedules
  • Alzheimer Disease
  • Therapeutics

• Profiling of the kynurenine pathway metabolism and quinolinic acid production in autism: defining the role of 16p11.2 mutation in abnormal glutamatergic neurotransmission in autism pathogenesis

  Lim, E. & Guillemin, G.

  15/03/16 → 14/03/17

  Project: Research

• Adaptation of respiratory chemoreception: role of inhibitory neuropeptides

  McMullan, S., Kumar, N., Power, J. & Abbott, S.

  18/02/18 → 31/12/20

  Project: Research

• Restoring Neuroprotective Sphingosine 1-phosphate Signalling in Alzheimer's Disease

  Don, A., Fath, T. & Karl, T.

  1/01/16 → 31/12/16

  Project: Research

• Investigating the role of large structural variation in MND by analysis of whole-genome sequencing data

  Fifita, J., Williams, K. & Blair, I.

  1/06/19 → 31/05/20

  Project: Research

• Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer’s Disease

  Don, A., Garner, B., Fath, T. & Rosen, H.

  1/01/16 → 31/12/19

  Project: Research

• Generation of a stem cell model for the validation of novel amyotrophic lateral sclerosis (ALS) candidate genes.

  Yang, S. & Blair, I.

  1/01/17 → …

  Project: Research

• Pre-clinical evaluation of novel therapies for clearance of TDP-43 in amyotrophic lateral sclerosis

  Chung, R., Walker, A. K., Ittner, L., Lee, A. & Rayner, S.

  1/01/19 → 31/12/19

  Project: Research

• Revealing the role of protein clearance pathways in sporadic ALS

  Chung, R., Lee, A., Rayner, S. & Yang, S.

  1/05/19 → 30/04/20

  Project: Research

• Validating the NLRP3 Inflammasome as a Therapeutic Target in Motor Neuron Disease

  Atkin, J., Woodruff, T. M., McCombe, P. A., Walker, A. K., Robertson, A. & Gordon, R.

  1/01/18 → 31/12/21

  Project: Research

• Developing next-generation pain therapies based on Cannabinoid derivatives

  Connor, M. & Bladen, C.

  15/05/18 → 15/05/19

  Project: Research

• The pharmacology and toxicity of synthetic cannabinoids

  Connor, M., Kassiou, M. & McGregor, I.

  1/01/16 → …

  Project: Research

• NSW Cancer Research Peptide Synthesis Facility

  Baker, M. S., Reddell, R., Robinson, P., Payne, R. J., Baxter, R. C., McCluskey, A., Pickett, H. A. & Bryan, T.

  1/07/18 → 30/06/22

  Project: Research

• Sydney Vital: Role of suppressor of cytokine signaling 3 (SOCS3) in lipopolysaccharide (LPS) induced oral cancer progression

  Vickery, K. & Chakraborty, R.

  25/03/19 → 21/03/20

  Project: Research

• NHMRC_ADNeT: The Australian Dementia Network (ADNeT): Bringing together Australia's dementia stakeholders

  Botelho Dias, C. & Hillebrandt, H.

  1/07/18 → 30/06/23

  Project: Research

• Sporadic ALS Australian Systems Genomics Consortium (SALSA- SGC)

  Blair, I., Wray, N., Benyamin, B., Henderson, R. D., Kiernan, M., Laing, N., Mathers, S., McCombe, P. A., Nicholson, G., Pamphlett, R., Rowe, D., Schultz, D., Visscher, P. M., Vucic, S., Williams, K., Zhao, Q., Al-Chalabi, A., Veldink, J., Van den Berg, L. & Henders, A. K.

  30/11/15 → 31/05/19

  Project: Research

• New nanoparticle strategies for efficient delivery and controlled release into the brain

  Shi, B.

  1/04/16 → 31/03/20

  Project: Research

• Understanding the early disease mechanisms of motor neuron disease and frontotemporal dementia

  Walker, A. K., Bye, C., Halliday, G., Atkin, J., Molloy, M. & Lee, V.

  1/01/17 → …

  Project: Research

  • Frontotemporal Dementia
  • Motor Neuron Disease
  • Queensland

• Manipulating oncogene addiction and immunity in the treatment of melanoma

  Rizos, H.

  1/01/16 → 31/12/20

  Project: Research

• Molecular determinants of risk, progression and treatment response in melanoma

  Kefford, R., Thompson, J., Hersey, P., Mann, G., Scolyer, R., Hayward, N. & Long, G.

  1/01/16 → …

  Project: Research

• Acquired resistance to PD1 inhibition in melanoma

  Rizos, H., Carlino, M., Kefford, R., Zhang, X. D., Menzies, A. M., Long, G., McGuire, H., Yang, J., Scolyer, R. & De St Groth, B. F.

  1/01/17 → 31/12/21

  Project: Research

• A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (The METRIC Study)

  Kefford, R., Gurney, H., Butala, R. & Grice, L.

  12/09/14 → …

  Project: Research

  • Triple Negative Breast Neoplasms
  • Multicenter Studies
  • glembatumumab vedotin
  • CR011-vcMMAE

• A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, MI or Stroke in Subjects with HF and CAD

  Brown, M. & Butala, R.

  1/09/15 → 30/06/17

  Project: Research

• A research assistant to build capacity in and use of Macquarie's bioreactor equipment: towards production and maintenance of live bioartificial tissues for sustainable scientific use

  Sen, I., Avolio, A., Gillatt, D., Zvyagin, A., De Deene, Y., Vickery, K., Fuerbach, A. & Parker, L.

  1/01/17 → …

  Project: Research

  • assistant

• Biomolecular Discovery and Design Research Centre

  Packer, N., Paulsen, I., Nevalainen, H., Haynes, P., Molloy, M., Atwell, B., Barron, A., Beggs, P., Bergquist, P. L., Brown, L., Cornish, J., Chung, R., De Deene, Y., Garcia-Bennett, A., Gillings, M., Goodchild, A., Guillemin, G., Hallinan, J., Hose, G., Jaschke, P., Mabbutt, B., Raftos, D., Ranganathan, S., Sofronov, G., Sunna, A., Tetu, S., Andersen, M., Willows, R., Ahn, C., Breen, E., Campbell, M., Care, A., Cordina, N., Curach, N., Everest Dass, A., Elbourne, L., Goold, H., Hassan, K., Kautto, L., Krisp, C., Kroukamp, H., Lee, A., Lin, C., Mackie, A., McKay, M., McQuade, L., Mirzaei, M., Mohamedali, A., Ostrowski, M., Parker, L., Pascovici, D., Penesyan, A., Shah, B., Sun, A., Thompson, E. & Williams, T.

  1/01/17 → …

  Project: Research

• Central aortic pressure as a target for optimization of cardiac resynchronization therapy

  Butlin, M. & Avolio, A.

  1/07/12 → 30/06/14

  Project: Research

• Glycosphingolipid synthesis inhibition: mechanism of regulation of arterial stiffness

  Avolio, A.

  1/01/15 → 31/12/15

  Project: Research

• Vascular endothelial response to reduced pulsatility

  Butlin, M., Avolio, A. & Gangoda, S.

  Project: Research

• Dynamic Characteristics of Retinal Vessels in Glaucoma: Effects of Systemic Hypertension (Lay title: Effects of High Blood Pressure on Retinal Hemodynamics in Glaucoma)

  Golzan, M., Avolio, A. & Graham, S. L.

  5/01/15 → 31/12/16

  Project: Research

  • hypertension

• Understanding how diabetic foot infections develop and progress

  Hu, H., Malone, M. & Vickery, K.

  1/01/17 → …

  Project: Research

• Investigating the diagnostic utility of hyperspectral retinal imaging in preclinical Alzheimer's disease

  Martins, R., Gillatt, D., Graham, S. L., Chatterjee, P., Goozee, K., Gupta, S., Shah, T. & Sohrabi, H.

  1/12/17 → 13/10/20

  Project: Research

• How big is your surface? A gas adsorption isotherm instrument for Multidisciplinary Material Science

  Garcia-Bennett, A., Packer, N., Strezov, V., Gore, D., Lang, C., Molina-Terriza, G., Liu, F., Xu, X., Denkova, D., Shi, B. & Lawson, T.

  1/01/16 → 31/12/16

  Project: Research

• Signalling pathways in the brain mediating the physiological effects of methamphetamine

  Goodchild, A. & Cornish, J.

  1/10/15 → 1/10/17

  Project: Research

• Is a hormone controlled by the brain driving high blood pressure in PKD?

  Hildreth, C., Phillips, J. K. & Goodchild, A.

  1/07/19 → 31/12/20

  Project: Research

• Molecular insight of biofilm in chronic infections and their response to current treatment using microbiome, metagenomics and meta-transcriptomics approaches

  Hu, H.

  1/08/17 → …

  Project: Research