Department of Biomedical Sciences

Projects

Projects per year 2006 2025

• 1 Curtailed
• 6 Not started
• 124 Active
• 177 Finished

Projects per year

Search results

• Epigenomic approaches to understand MND disease variability

  Williams, K., Blair, I., Rowe, D. & Nicholson, G.

  26/03/15 → 25/03/16

  Project: Research

• Next-Generation Sequencing of Australian sporadic MND patients to identify genetic risk factors

  Blair, I., Kiernan, M., Pamphlett, R., Denis, B., Wilson, W. & Williams, K.

  26/03/15 → 25/03/16

  Project: Research

• Optimising the protective properties of protein disulphide isomerase in motor neuron disease

  Atkin, J. & Cole, N.

  1/06/15 → 31/05/16

  Project: Research

• Proteomic studies to identify the defects in protein-protein interactions and cellular signalling pathways caused by mutations in a newly identified familial ALS gene

  Chung, R., Blair, I., Yerbury, J., Lee, A., Molloy, M. & Atkin, J.

  1/06/15 → 31/05/16

  Project: Research

• New inhibitors of kynurenine-3-monooxygenase for Alzheimer's disease therapy

  Guillemin, G. & Lovejoy, D.

  15/06/15 → 30/04/17

  Project: Research

  • Kynurenine 3-Monooxygenase
  • Appointments and Schedules
  • Alzheimer Disease
  • Therapeutics

• Screening the eyes for early diagnosis of Alzheimer's disease

  Graham, S. L. & Golzan, M.

  1/07/15 → 30/06/16

  Project: Research

• Improving Sunitinib Efficacy and tolerability in patients with metastatic clear cell carcinoma of the kidney by using a 14/7 day schedule and ToxicityAdjusted Dosing (ISE TAD147)

  Gurney, H.

  1/07/15 → 1/07/17

  Project: Research

• CSF flow in the spinal cord and subarachnoid space with relevance to syringomyelia pathogenesis

  Stoodley, M., Bilston, L. & Hemley, S.

  1/07/15 → 31/03/17

  Project: Research

• Biosecurity Futures Research Centre

  Taylor, P., Gillings, M., Raftos, D., Leishman, M., Sunna, A., Bishop, M., Barron, A., Beattie, A., Beaumont, L., Connally, R., Grech, A., Griffith, S., Guillemin, G., Hughes, L., Inglis, D., Jamie, I., Jamie, J., Lu, Y., Morelli De andrade, R., Nevalainen, H., Park, S. J., Perez, J., Power, M., Ranjan, R. & Vickery, K.

  1/07/15 → …

  Project: Research

• Investigating mechanisms of dementia and motor neuron disease

  Walker, A. K.

  31/07/15 → 30/09/17

  Project: Research

  • Motor Neuron Disease
  • Dementia

• 3D Printing Facility

  Withford, M., Downes, J., Twamley, J., Inglis, D., Jackson, S., Clark, S., O'Neill, C. J., Pearson, N., O'Reilly, S., Griffin, B., Foley, S., Chung, R., Atkin, J., McMullan, S., Cartmill, J., Appleyard, R. & Tristant, Y.

  23/08/15 → 22/08/16

  Project: Research

• Generation of individualised zebrafish models of MND

  Don, E. & Ekker, S.

  1/09/15 → 30/11/15

  Project: Research

• A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, MI or Stroke in Subjects with HF and CAD

  Brown, M. & Butala, R.

  1/09/15 → 30/06/17

  Project: Research

• Signalling pathways in the brain mediating the physiological effects of methamphetamine

  Goodchild, A. & Cornish, J.

  1/10/15 → 1/10/17

  Project: Research

• Australia China Young Scientist Exchange Program

  Lim, E.

  1/11/15 → 14/11/15

  Project: Research

• A Phase III, International, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Clinical Worsening Study of UT-15C in Subjects with Pulmonary Arterial HTN Receiving Background Oral Monotherapy

  Brown, M. & Butala, R.

  1/11/15 → 30/11/18

  Project: Research

• An Open-Label Extension Study of UT-15C in Subjects with Pulmonary Arterial Hypertension - A Long-Term Follow-Up to Protocol TDE-PH-310

  Brown, M. & Butala, R.

  1/11/15 → 31/12/20

  Project: Research

• CASS Foundation Travel Award: 26th International Symposium on ALS/MND

  Walker, A. K.

  12/11/15 → 31/12/16

  Project: Research

• FINESSE - A multicenter study to evaluate the efficacy and safety of finerenone compared to eplerenone on morbidity and mortality in patients with chronic heart failure and reduced ejection fraction..

  Brown, M. & Butala, R.

  15/11/15 → 2/05/16

  Project: Research

• Sporadic ALS Australian Systems Genomics Consortium (SALSA- SGC)

  Blair, I., Wray, N., Benyamin, B., Henderson, R. D., Kiernan, M., Laing, N., Mathers, S., McCombe, P. A., Nicholson, G., Pamphlett, R., Rowe, D., Schultz, D., Visscher, P. M., Vucic, S., Williams, K., Zhao, Q., Al-Chalabi, A., Veldink, J., Van den Berg, L. & Henders, A. K.

  30/11/15 → 31/05/19

  Project: Research

• Modulating the kynurenine pathway in Alzheimer's disease: a method of attenuating neuroinflammation and a potential disease biomarker

  Guillemin, G.

  1/01/16 → 31/12/16

  Project: Research

• Mechanisms underlying the repellent effects of predator odours in rodents

  Connor, M., McGregor, I., Crowther, M. & Banister, S.

  1/01/16 → …

  Project: Research

• Manipulating Oncogenic Signalling for the treatment of KIT-mutant melanoma

  Rizos, H.

  1/01/16 → 31/12/16

  Project: Research

• Identification of the biochemical determinants of neuron death and survival in a new mouse model of motor neuron disease

  Walker, A. K. & Atkin, J.

  1/01/16 → …

  Project: Research

• Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer’s Disease

  Don, A., Garner, B., Fath, T. & Rosen, H.

  1/01/16 → 31/12/19

  Project: Research

• Unravelling the molecular basis of amyotrophic lateral sclerosis

  Williams, K.

  1/01/16 → …

  Project: Research

• How big is your surface? A gas adsorption isotherm instrument for Multidisciplinary Material Science

  Garcia-Bennett, A., Packer, N., Strezov, V., Gore, D., Lang, C., Molina-Terriza, G., Liu, F., Xu, X., Denkova, D., Shi, B. & Lawson, T.

  1/01/16 → 31/12/16

  Project: Research

• Identification of environmental risk factors for sporadic motor neurone disease in Australia

  Guillemin, G., Rowe, D., Rodgers, K., Bowling, L., Stommel, E. & Allorge, D.

  1/01/16 → 30/06/17

  Project: Research

  • Motor Neuron Disease
  • Appointments and Schedules

• The pharmacology and toxicity of synthetic cannabinoids

  Connor, M., Kassiou, M. & McGregor, I.

  1/01/16 → …

  Project: Research

• Restoring Neuroprotective Sphingosine 1-phosphate Signalling in Alzheimer's Disease

  Don, A., Fath, T. & Karl, T.

  1/01/16 → 31/12/16

  Project: Research

• Vascular targeting combined with radiosurgery in an arteriovenous malformation rat model

  Gauden, A. & Stoodley, M.

  1/01/16 → …

  Project: Research

• PKD, Heart Disease and the Sympathetic Nervous System

  Phillips, J. K. & Hildreth, C.

  1/01/16 → 31/03/17

  Project: Research

  • Sympathetic Nervous System
  • Heart Diseases
  • Appointments and Schedules

• Manipulating oncogene addiction and immunity in the treatment of melanoma

  Rizos, H.

  1/01/16 → 31/12/20

  Project: Research

• A bioreactor complex for automated production and maintenance of live bioartifical tissues

  Sen, I., Avolio, A., Gillatt, D., Zvyagin, A., Goldys, E., De Deene, Y. & Kumaraswamy Annayya Chetty Sreenivasan, V.

  1/01/16 → 31/12/16

  Project: Research

• Molecular determinants of risk, progression and treatment response in melanoma

  Kefford, R., Thompson, J., Hersey, P., Mann, G., Scolyer, R., Hayward, N. & Long, G.

  1/01/16 → …

  Project: Research

• Vascular mechanisms of dementia: the role of pulsatile haemodynamics

  Avolio, A.

  1/01/16 → 31/12/16

  Project: Research

• "Re-educating" immune cells as a combination therapy to limit breast cancer metastasis

  Heng, B. & Guillemin, G.

  1/01/16 → 1/01/17

  Project: Research

• Investigating the genetic and epigenetic basis of amyotrophic lateral sclerosis (Scholarship Top-up Emily McCann)

  Blair, I. & McCann, E.

  1/01/16 → 31/12/18

  Project: Research

• The role of mutant cyclin F in amyotrophic lateral sclerosis

  Blair, I., Atkin, J., Chung, R., Yerbury, J., Ooi, L., Rowe, D., Burgio, G., Nicholson, G., Halliday, G., Molloy, M. & Karl, T.

  1/01/16 → 31/12/18

  Project: Research

• Developing insight into the molecular origins of familial and sporadic frontotemporal dementia and amyotrophic lateral sclerosis

  Blair, I., Atkin, J., Chung, R., Guillemin, G., Ooi, L., Denis, B., Molloy, M., Yerbury, J., Cole, N., Karl, T. & Wilson, W.

  1/01/16 → …

  Project: Research

• Understanding factors involved in the development of hypertension

  McMullan, S., Allen, A., Fong, A. & Menuet, C.

  1/01/16 → 31/08/19

  Project: Research

• Development and validation of a pediatric transfer function for deriving central aortic blood pressure from radial artery tonometry in children

  Skilton, M. R., Avolio, A., Ayer, J. G., Butlin, M., Celermajer, D., Al Haj Qasem, A. & Tan, T. Y.

  1/01/16 → 31/12/18

  Project: Research

• BioMolecular Frontiers Research Centre (BMFRC) Mature Centre 2015

  Packer, N., Paulsen, I., Nevalainen, H., Haynes, P., Molloy, M., Atwell, B., Barron, A., Beggs, P., Bergquist, P. L., Brown, L., Cornish, J., Chung, R., De Deene, Y., Gillings, M., Goodchild, A., Guillemin, G., Hallinan, J., Hose, G., Jaschke, P., Lanfear, R., Mabbutt, B., Raftos, D., Ranganathan, S., Sofronov, G., Stoodley, M., Sunna, A., Tetu, S., Willows, R. & Wright, I.

  1/01/16 → 31/12/16

  Project: Research

• A strongly adherent graphene coating on platinum electrodes for cochlear implants

  Liu, Y., Shi, B. & Lawson, T.

  6/01/16 → 29/02/16

  Project: Research

• Seeking a cure for Machado Joseph disease, a prevalent neurodegenerative disease within Aboriginal communities of northeast Arnhem Land

  Laird, A., Nicholson, G., Becker, T. & Giacomotto, J.

  18/01/16 → 30/06/17

  Project: Research

  • Machado-Joseph Disease
  • Neurodegenerative Diseases
  • Appointments and Schedules

• Identifying mechanisms responsible for ubiquitination of TAR DNA-binding protein 43 (TDP-43) in ALS pathogenesis

  Lee, A., Chung, R., Blair, I. & Atkin, J.

  1/02/16 → 18/02/17

  Project: Research

  • Ubiquitination
  • DNA-Binding Proteins
  • Appointments and Schedules

• Pre-clinical therapeutic testing and biochemical changes associated with neuron survival in a validated TDP-43 mouse model of MND

  Walker, A. K.

  1/02/16 → 31/01/17

  Project: Research

• Elucidating the Pathogenesis of Sporadic Motor Neurone Disease Using Zebrafish Models

  Cole, N., Nicholson, G. & Walker, A.

  11/03/16 → 10/03/17

  Project: Research

• Profiling of the kynurenine pathway metabolism and quinolinic acid production in autism: defining the role of 16p11.2 mutation in abnormal glutamatergic neurotransmission in autism pathogenesis

  Lim, E. & Guillemin, G.

  15/03/16 → 14/03/17

  Project: Research

• Biomagnification of the biotoxin BMAA in the environment

  Guillemin, G., Rodgers, K., Cox, P., Bowling, L. & Iqbal, K.

  22/03/16 → 31/03/21

  Project: Research