Department of Biomedical Sciences

Projects

Projects per year 2006 2025

• 1 Curtailed
• 6 Not started
• 124 Active
• 177 Finished

Projects per year

Search results

• Identification of new ophthalmic biomarkers and their association to brain amyloid burden in preclinical Alzheimer's disease

  Shah, T.

  1/01/18 → 31/12/18

  Project: Other

• A transgenic zebrafish model to study sporadic motor neuron disease for drug screening studies

  Laird, A., Blair, I. & Nicholson, G.

  1/01/18 → 31/12/18

  Project: Other

• Glycoproteomic characterisation of pathogenic gene mutations in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)

  Lee, A., Moh, E., Vidal Robau, M., Chung, R., Atkin, J., Thaysen-Andersen, M. & Packer, N.

  1/07/18 → 31/12/18

  Project: Research

• Proteome homeostasis dysfunction in axon terminals as a cause of MND

  Blair, I., Molloy, M., Yerbury, J., Ooi, L. & Vendruscolo, M.

  1/01/18 → 31/12/18

  Project: Other

• Investigating the genetic and epigenetic basis of amyotrophic lateral sclerosis (Scholarship Top-up Emily McCann)

  Blair, I. & McCann, E.

  1/01/16 → 31/12/18

  Project: Research

• The role of mutant cyclin F in amyotrophic lateral sclerosis

  Blair, I., Atkin, J., Chung, R., Yerbury, J., Ooi, L., Rowe, D., Burgio, G., Nicholson, G., Halliday, G., Molloy, M. & Karl, T.

  1/01/16 → 31/12/18

  Project: Research

• Development and validation of a pediatric transfer function for deriving central aortic blood pressure from radial artery tonometry in children

  Skilton, M. R., Avolio, A., Ayer, J. G., Butlin, M., Celermajer, D., Al Haj Qasem, A. & Tan, T. Y.

  1/01/16 → 31/12/18

  Project: Research

• New directions for early diagnosis of MND: a large-scale longitudinal analysis of multiple biomarkers to find diagnostic and prognostic "fingerprints"

  Guillemin, G., Rowe, D., Blair, I., Atkin, J., Zetterberg, H., Rogers, M., Lovejoy, D., Lim, E. & Tan, V.

  1/01/18 → 31/12/18

  Project: Research

• Investigating cyanobacteria toxin as a causative environmental factor in pathogenesis of ALS

  Lim, E., Tan, V., Guillemin, G., Peyrin, J. M. & SH Tan, P.

  1/02/18 → 31/01/19

  Project: Other

• Inducing autophagy to treat motor neuron disease

  Laird, A., Don, E., Shahheydari, H., Cole, N. & Nicholson, G.

  15/03/18 → 14/03/19

  Project: Other

• Seeking genomic factors that modify the progression of MND

  Williams, K., Blair, I., Bauer, D. C., Twine, N., Nicholson, G. & Rowe, D.

  20/04/18 → 19/04/19

  Project: Research

• The role of TDP-43 pathology-associated astrocytosis in Motor Neuron Disease.

  Ittner, L. & Ke, Y.

  1/11/18 → 30/04/19

  Project: Other

• Developing next-generation pain therapies based on Cannabinoid derivatives

  Connor, M. & Bladen, C.

  15/05/18 → 15/05/19

  Project: Research

• Sporadic ALS Australian Systems Genomics Consortium (SALSA- SGC)

  Blair, I., Wray, N., Benyamin, B., Henderson, R. D., Kiernan, M., Laing, N., Mathers, S., McCombe, P. A., Nicholson, G., Pamphlett, R., Rowe, D., Schultz, D., Visscher, P. M., Vucic, S., Williams, K., Zhao, Q., Al-Chalabi, A., Veldink, J., Van den Berg, L. & Henders, A. K.

  30/11/15 → 31/05/19

  Project: Research

• Post-traumatic stress disorder: Connectivity of the hyper-reactivity centre

  Goodchild, A. & McMullan, S.

  4/07/17 → 23/06/19

  Project: Research

• MISC_Sydney Vital: To investigate circulating tumour DNA as a biomarker of resistance in metastatic uveal melanoma treated with PKC inhibitor (LXS196)

  Rizos, H. & Park, J.

  1/07/18 → 30/06/19

  Project: Other

• OOA_Perpetual: Why does kidney disease reduce heart health in women?

  Phillips, J. K., Hildreth, C. & Butlin, M.

  1/07/18 → 1/07/19

  Project: Research

• How kidney disease rewires the brain to reduce heart health: changes to support cells in the brain

  Phillips, J. K. & Hildreth, C.

  3/07/17 → 2/07/19

  Project: Research

• Understanding factors involved in the development of hypertension

  McMullan, S., Allen, A., Fong, A. & Menuet, C.

  1/01/16 → 31/08/19

  Project: Research

• Biomedical engineering workforce

  Taksa, L., Hull, D., Guo, F., Bowles, M., Kalfa, S., Appleyard, R., Turner, D., Paterson, W., Paterson, R. & Cousins, L.

  23/05/19 → 27/09/19

  Project: Research

• SAX Institute and NSW Ministry of Health ($36,900) for a project entitled: ‘Biomedical engineering: a critical workforce in healthcare delivery

  Taksa, L., Hull, D., Guo, F., Kalfa, S., Appleyard, R. & Turner, D.

  23/05/19 → 27/09/19

  Project: Research

• The use of AeriSeal® in the management of collateral ventilation positive COPD patients undergoing ELVR (Endoscopic Lung Volume Reduction) utilizing endobronchial valves

  Ing, A. & Cunningham, J.

  1/08/18 → 31/12/19

  Project: Other

• Diagnosing High-Risk of Recurrence Stage II Colorectal Cancer

  Baker, M. S., Ahn, C. & Chapuis, P.

  1/01/19 → 31/12/19

  Project: Research

• The tau interactome – novel functions in neuronal physiology

  Ittner, L.

  1/11/18 → 31/12/19

  Project: Other

• Pre-clinical evaluation of novel therapies for clearance of TDP-43 in amyotrophic lateral sclerosis

  Chung, R., Walker, A. K., Ittner, L., Lee, A. & Rayner, S.

  1/01/19 → 31/12/19

  Project: Research

• Liquid Biopsy for Personalised Monitoring of Melanoma Patients

  Rizos, H., Ziman, M., Millward, M., Hayward, N. K., Amanuel, B., Gray, E., Khattak, M., Lo, J. & Beckhouse, A.

  1/01/17 → 31/12/19

  Project: Research

• OOA_IPF: Establishing an advanced platform for single cell analysis

  Rizos, H.

  1/01/19 → 31/12/19

  Project: Research

• Exosomes: predictive and prognostic biomarkers in melanoma

  Diefenbach, R. & Rizos, H.

  1/01/18 → 31/12/19

  Project: Research

• JG Lang Travel Grant to support attendance at the International Symposium on ALS/MND in Perth 4-6 December 2019

  Wright, A.

  1/12/19 → 31/12/19

  Project: Research

• Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer’s Disease

  Don, A., Garner, B., Fath, T. & Rosen, H.

  1/01/16 → 31/12/19

  Project: Research

• Slowing progression of Alzheimer's disease by modulating the kynurenine pathway

  Guillemin, G., Lovejoy, D., Ittner, A., Braidy, N., Doecke, J., Lim, E., Nicolazzo, J. & Ittner, L.

  1/01/17 → 31/12/19

  Project: Research

• Solid-State Probe for NMR Studies at Macquarie University

  Jiang, Y., Jacob, D., Wu, S., Garcia-Bennett, A., Venkatesan, K., Lu, Y., Zhao, S. & Shi, B.

  1/01/19 → 31/12/19

  Project: Other

• Investigating the prevalence and mechanisms of orthostatic intolerance in young adults with joint hypermobility disorders

  Peebles, K., Pacey, V., Butlin, M., Avolio, A. & Collins, F.

  1/01/18 → 31/12/19

  Project: Research

• OOA_Brain Foundation: In vitro testing of thrombotic nanodisks for vascular targeting of AVMs

  Zhao, Z., Stoodley, M., Shi, B., McRobb, L. & Fu, A.

  1/01/19 → 31/12/19

  Project: Research

• Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

  Morsch, M. & Graeber, M.

  1/01/17 → 31/12/19

  Project: Research

• Systemic regulation of neuronal circuits in cognition and behaviour

  Ittner, L. & Ittner, A.

  1/11/18 → 31/12/19

  Project: Other

• Fight on the Beaches Research Grant

  Baker, M. S.

  22/02/19 → 31/12/19

  Project: Research

• Custodians of the CNS: Microglia regulate the spread of disease proteins

  Morsch, M. & Chung, R.

  1/01/18 → 31/12/19

  Project: Other

• Examining the unique susceptibility of neurons in Motor Neuron Disease (MND)

  Shahheydari, H., Don, E. & Atkin, J.

  1/01/18 → 31/12/19

  Project: Other

• Macquarie University Centre for Motor Neuron Disease Research

  Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, E., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A. K., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, M., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.

  1/01/17 → 31/12/19

  Project: Research

• Targeting Post-synaptic Tau to Treat Alzheimer's Disease

  Ittner, L., Housley, G., Kassiou, M., Karl, T. & Van Eersel, J.

  1/11/18 → 31/12/19

  Project: Other

• Establishment of archival freezer storage bay

  Chung, R., Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. K. & Laird, A.

  1/01/19 → 31/12/19

  Project: Research

• High-content screening platform

  Atkin, J., Connor, M., Blair, I., Rizos, H., Phillips, J. K. & Laird, A.

  1/01/19 → 31/12/19

  Project: Research

• Self-assembled hydrogels as a model for neurodegeneration

  Martin, A.

  1/01/19 → 31/01/20

  Project: Other

• Sydney Vital: Role of suppressor of cytokine signaling 3 (SOCS3) in lipopolysaccharide (LPS) induced oral cancer progression

  Vickery, K. & Chakraborty, R.

  25/03/19 → 21/03/20

  Project: Research

• New nanoparticle strategies for efficient delivery and controlled release into the brain

  Shi, B.

  1/04/16 → 31/03/20

  Project: Research

• Revealing the role of protein clearance pathways in sporadic ALS

  Chung, R., Lee, A., Rayner, S. & Yang, S.

  1/05/19 → 30/04/20

  Project: Research

• Investigating the role of large structural variation in MND by analysis of whole-genome sequencing data

  Fifita, J., Williams, K. & Blair, I.

  1/06/19 → 31/05/20

  Project: Research

• Targeting the nucleo-cytoplasmic transport machinery in sporadic and familial ALS

  Morsch, M., Lee, A., Walker, A. K. & Chung, R.

  1/06/19 → 31/05/20

  Project: Research

• Does inflammation in the brain lead to hypertension in kidney disease?

  Phillips, J. K. & Hildreth, C.

  1/07/19 → 1/06/20

  Project: Research