Department of Biomedical Sciences

Projects

Projects per year 2006 2025

• 1 Curtailed
• 6 Not started
• 124 Active
• 177 Finished

Projects per year

Search results

• Research

  Does inflammation in the brain lead to hypertension in kidney disease?

  Phillips, J. K. & Hildreth, C.

  1/07/19 → 1/06/20

  Project: Research

• Is it the same? How does hypothalamus produce hypertension in acquired and inherited kidney disease vs. essential hypertension

  Phillips, J. K. & Hildreth, C.

  1/07/20 → 31/12/21

  Project: Research

• Calpeptin, and related candidates, for the treatment of Machado Joseph disease

  Laird, A., Nicholson, G., Walker, A. K., Cole, N., Lee, A., Morsch, M., Davis, R., Guillemin, G., Atkin, J. & Ooi, L.

  1/01/18 → 31/12/21

  Project: Research

• Slowing progression of Alzheimer's disease by modulating the kynurenine pathway

  Guillemin, G., Lovejoy, D., Ittner, A., Braidy, N., Doecke, J., Lim, E., Nicolazzo, J. & Ittner, L.

  1/01/17 → 31/12/19

  Project: Research

• Unravelling the molecular basis of amyotrophic lateral sclerosis

  Williams, K.

  1/01/16 → …

  Project: Research

• The role of mutant CYLD in frontotemporal dementia and motor neuron disease

  Blair, I., Dobson-Stone, C., Kwok, J. B., Atkin, J., Ooi, L., Ittner, A., Lee, A., Mather, K. A., Thompson, E. & Burgio, G.

  1/01/18 → 31/12/21

  Project: Research

• Acquired resistance to PD1 inhibition in melanoma

  Rizos, H., Carlino, M., Kefford, R., Zhang, X. D., Menzies, A. M., Long, G., McGuire, H., Yang, J., Scolyer, R. & De St Groth, B. F.

  1/01/17 → 31/12/21

  Project: Research

• ELIMINATE: OEstrogen Lowering Intervention May Increase NeoAdjuvant Therapy Efficacy. Randomised phase II trial of neoadjuvant chemotherapy +/- concurrent aromatase inhibitor endocrine therapy to down

  Kefford, R. & Butala, R.

  1/12/14 → …

  Project: Research

• A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (The METRIC Study)

  Kefford, R., Gurney, H., Butala, R. & Grice, L.

  12/09/14 → …

  Project: Research

  • Triple Negative Breast Neoplasms
  • Multicenter Studies
  • glembatumumab vedotin
  • CR011-vcMMAE

• Investigating the prevalence and mechanisms of orthostatic intolerance in young adults with joint hypermobility disorders

  Peebles, K., Pacey, V., Butlin, M., Avolio, A. & Collins, F.

  1/01/18 → 31/12/19

  Project: Research

• A Phase III, International, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Clinical Worsening Study of UT-15C in Subjects with Pulmonary Arterial HTN Receiving Background Oral Monotherapy

  Brown, M. & Butala, R.

  1/11/15 → 30/11/18

  Project: Research

• Dynamic Characteristics of Retinal Vessels in Glaucoma: Effects of Systemic Hypertension (Lay title: Effects of High Blood Pressure on Retinal Hemodynamics in Glaucoma)

  Golzan, M., Avolio, A. & Graham, S. L.

  5/01/15 → 31/12/16

  Project: Research

  • hypertension

• Attending the 20th Annual Scientific Meeting of European Society of Hypertension, June 18 - 21, 2010 Oslo, Norway

  Adji, A., Avolio, A., Thatcher, B. & O'Rourke, M.

  26/09/10 → 30/09/10

  Project: Research

• Live-cell confocal microscope

  Atkin, J., Sundaramoorthy, V., Halloran, M., Avolio, A., Butlin, M., Chung, R., Morsch, M., Lee, A., Shi, B., Connor, M., Goodchild, A., Hassan, S., Guillemin, G., Lim, E., Lovejoy, D., Adams, S., Heng, B., McMullan, S., Phillips, J. K., Hildreth, C., Rizos, H., Shahheydari, H., Irvine, M., Lauter, C., Boyd, S. & Vickery, K.

  12/02/15 → 31/12/15

  Project: Research

• Vascular endothelial response to reduced pulsatility

  Butlin, M., Avolio, A. & Gangoda, S.

  Project: Research

• Clinical trial of a suprachoroidal visual prosthesis for the profoundly vision impaired

  Fung, A., Suaning, G., Lovell, N., Grigg, J., daCruz, A. M., Morley, J. W., James, N., Tumuluri, K., Ayton, L. & McCluskey, P.

  1/01/17 → …

  Project: Research

• How big is your surface? A gas adsorption isotherm instrument for Multidisciplinary Material Science

  Garcia-Bennett, A., Packer, N., Strezov, V., Gore, D., Lang, C., Molina-Terriza, G., Liu, F., Xu, X., Denkova, D., Shi, B. & Lawson, T.

  1/01/16 → 31/12/16

  Project: Research

• OOA_Brain Foundation: In vitro testing of thrombotic nanodisks for vascular targeting of AVMs

  Zhao, Z., Stoodley, M., Shi, B., McRobb, L. & Fu, A.

  1/01/19 → 31/12/19

  Project: Research

• An Open-Label Extension Study of UT-15C in Subjects with Pulmonary Arterial Hypertension - A Long-Term Follow-Up to Protocol TDE-PH-310

  Brown, M. & Butala, R.

  1/11/15 → 31/12/20

  Project: Research

• The AUstralian-Multidomain Approach to Reduce Dementia Risk by PrOtecting Brain Health With Lifestyle Intervention

  Fuller, S., Shah, T., Martins, R., Botelho Dias, C., Sohrabi, H., Chatterjee, P. & Hillebrandt, H.

  1/01/20 → 30/09/24

  Project: Research

• Signalling pathways in the brain mediating the physiological effects of methamphetamine

  Goodchild, A. & Cornish, J.

  1/10/15 → 1/10/17

  Project: Research

• Is a hormone controlled by the brain driving high blood pressure in PKD?

  Hildreth, C., Phillips, J. K. & Goodchild, A.

  1/07/19 → 31/12/20

  Project: Research

• Lighthouse II: A confirmatory, randomized, placebo-controlled, group-sequential trial to investigate the efficacy and safety of Triumeq in patients with Amyotrophic Lateral Sclerosis (ALS): The Lighthouse II Trial

  Gold, J., Van den Berg, L. & Chapman, N.

  21/08/20 → 31/12/22

  Project: Research

• The primitive startle reflex: implications for post traumatic stress disorders

  Goodchild, A. & McMullan, S.

  1/10/16 → …

  Project: Research

• Biomolecular Discovery and Design Research Centre

  Packer, N., Paulsen, I., Nevalainen, H., Haynes, P., Molloy, M., Atwell, B., Barron, A., Beggs, P., Bergquist, P. L., Brown, L., Cornish, J., Chung, R., De Deene, Y., Garcia-Bennett, A., Gillings, M., Goodchild, A., Guillemin, G., Hallinan, J., Hose, G., Jaschke, P., Mabbutt, B., Raftos, D., Ranganathan, S., Sofronov, G., Sunna, A., Tetu, S., Andersen, M., Willows, R., Ahn, C., Breen, E., Campbell, M., Care, A., Cordina, N., Curach, N., Everest Dass, A., Elbourne, L., Goold, H., Hassan, K., Kautto, L., Krisp, C., Kroukamp, H., Lee, A., Lin, C., Mackie, A., McKay, M., McQuade, L., Mirzaei, M., Mohamedali, A., Ostrowski, M., Parker, L., Pascovici, D., Penesyan, A., Shah, B., Sun, A., Thompson, E. & Williams, T.

  1/01/17 → …

  Project: Research

• Establishing a centralised biobank for biomedical research

  Rizos, H., Kefford, R., Atkin, J., Blair, I., Guillemin, G., Rowe, D., Parakh, S., Sultana, J., Fifita, J. & Tan, V.

  1/01/15 → 31/12/15

  Project: Research

  • Melanoma
  • Appointments and Schedules
  • Mars
  • Organized Financing

• Biomolecular Frontiers Research Centre (BMFRC)

  Packer, N., Paulsen, I., Baker, M., Bergquist, P. L., Nevalainen, H., Haynes, P., Molloy, M., Hancock, W., Ranganathan, S., Wood, G., Mabbutt, B., Willows, R., Atwell, B., Brown, L., Rabeau, J., Liu, F., Roberts, T., Sunna, A., Kolarich, D., Nakano, M., Jensen, P., Godlewski, M., Kautto, L., Grinyer, J., McQuade, L., McKay, M., Gibbs, M., Te'o, J., Learmonth, G., Tetu, S., Hassan, K., Elbourne, L., Fanayan, S., Gillings, M. & Stokes, H.

  1/09/06 → 31/12/15

  Project: Research

• Australia Japan Emerging Researchers Exchange Program Linking Australia and Japan through our mid career scientists

  Burgio, G.

  4/11/14 → 14/11/14

  Project: Research

• Pre-clinical therapeutic testing and biochemical changes associated with neuron survival in a validated TDP-43 mouse model of MND

  Walker, A. K.

  1/02/16 → 31/01/17

  Project: Research

• Improving Sunitinib Efficacy and tolerability in patients with metastatic clear cell carcinoma of the kidney by using a 14/7 day schedule and ToxicityAdjusted Dosing (ISE TAD147)

  Gurney, H.

  1/07/15 → 1/07/17

  Project: Research

• Safety Study to evaluate the risk of seizure among subjects with Metastatic Castration-Resistant Prostate Cancer (mCCRPC) treated with Enzalutamide (UPWARD study)

  Gurney, H. & Butala, R.

  1/05/14 → …

  Project: Research

• Identification of early stage diagnosis of colorectal cancer

  Sharma, S. & Baker, M. S.

  1/09/17 → 30/09/18

  Project: Research

• A novel approach for targeted delivery of nanotherapeutics to the brain for the treatment of Alzheimer’s disease

  Shi, B.

  1/01/18 → 31/12/18

  Project: Research

• Seeking a cure for Machado Joseph disease, a prevalent neurodegenerative disease within Aboriginal communities of northeast Arnhem Land

  Laird, A., Nicholson, G., Becker, T. & Giacomotto, J.

  18/01/16 → 30/06/17

  Project: Research

  • Machado-Joseph Disease
  • Neurodegenerative Diseases
  • Appointments and Schedules

• COAD-P002: Examine the Effects of CocoMCT® on Clinical Factors Related to Health, Cognition, Quality of Life and Alzheimer's Disease: Double-Blind, Randomized Controlled Feeding Interventional Trial

  Botelho Dias, C. & Hillebrandt, H.

  1/01/20 → 31/12/23

  Project: Research

• Endeavour Research Fellowship 2018

  Shi, B.

  1/04/18 → 30/09/18

  Project: Research

• THE KYNURENINE PATHWAY IN NEUROINFLAMMATORY DISEASES: TRANSLATION TO PROGNOSTICS AND THERAPEUTICS

  Guillemin, G.

  30/11/19 → 29/11/24

  Project: Research

• Neurotoxicity induced by environmental amino acids-mimetic toxins through inflammation

  Guillemin, G. & Mortaud, S.

  1/01/19 → 31/12/22

  Project: Research

  File

• IDENTIFICATION OF NEW BIOMARKERS FOR SEVERITY, DISEASE PROGRESSION AND RESPONSE TO TREATMENT FOR COVID-19

  Guillemin, G.

  1/06/20 → 1/12/20

  Project: Research

  File

• Biomarker-based identification of at-risk patients with COVID-19

  Guillemin, G. & Brew, B.

  1/06/20 → 31/12/21

  Project: Research

  File

• Acoustic liquid handling robotics for bioactive compound discovery

  Karuso, P., Poulsen, S., Avery, V., Quinn, R., Jonathan, B., Scanlon, M., Cooper, M., Booker, G., Professor, S., Guillemin, G., Smith, J., Ryan, J. & Peat, T.

  10/03/17 → …

  Project: Research

• BMAA contamination and toxicity

  Guillemin, G.

  1/01/15 → 31/12/15

  Project: Research

• Identification of environmental risk factors for sporadic motor neurone disease in Australia

  Guillemin, G., Rowe, D., Rodgers, K., Bowling, L., Stommel, E. & Allorge, D.

  1/01/16 → 30/06/17

  Project: Research

  • Motor Neuron Disease
  • Appointments and Schedules

• Biomagnification of the biotoxin BMAA in the environment

  Guillemin, G., Rodgers, K., Cox, P., Bowling, L. & Iqbal, K.

  22/03/16 → 31/03/21

  Project: Research

• The Potential of Noncoding RNAs in Saliva and Urine as Biomarkers of Prostate Cancer

  Gurney, H.

  25/08/14 → 3/04/15

  Project: Research

• Novel peripherally‐restricted cannabinoids to treat impaired neuromuscular synaptic transmission in myasthenia gravis and other neurological disorders

  Phillips, W. D., McGregor, I. S., Arnold, J., Bowen, M. T., Banister, S., Reddel, S. W., Odierna, L. & Morsch, M.

  20/11/18 → 31/12/22

  Project: Research

• Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

  Morsch, M. & Graeber, M.

  1/01/17 → 31/12/19

  Project: Research

• Single-session Introduction of Mutations in Parallel Lines (SIMPL)

  Ittner, L.

  1/01/21 → 31/12/23

  Project: Research

• Development of next-generation targeted therapies for epilepsy and pain based on cannabinoid derivatives

  Bladen, C. & Connor, M.

  3/07/17 → …

  Project: Research

• The pharmacology and toxicity of synthetic cannabinoids

  Connor, M., Kassiou, M. & McGregor, I.

  1/01/16 → …

  Project: Research