Department of Biomedical Sciences

Projects

Projects per year 2006 2025

• 1 Curtailed
• 6 Not started
• 123 Active
• 177 Finished

Projects per year

Search results

• Active

  Modulating actin dynamics in ALS/MND as a novel therapeutic approach

  Atkin, J., Woodruff, T. M., Karl, T., Craik, D., Guillemin, G. & Laird, A.

  4/01/21 → 3/01/24

  Project: Research

• Novel nanotechnology strategies for drug delivery to the brain and preclinical evaluation of therapies

  Shi, B.

  1/01/21 → 31/12/25

  Project: Research

• Targeting pathogenic TAR DNA-binding protein 43 to treat frontotemporal dementia and motor neuron disease

  Ke, Y., van Hummel, A., Ariawan, D., Ittner, L. & Martin, A.

  1/01/21 → 31/12/23

  Project: Research

• Unravelling the molecular mechanism of tau spread in Alzheimer's disease

  Fath, T., Van Eersel, J., Przybyla, M. & Ittner, L.

  1/01/21 → 31/12/24

  Project: Research

• Single-session Introduction of Mutations in Parallel Lines (SIMPL)

  Ittner, L.

  1/01/21 → 31/12/23

  Project: Research

• Microglia and the inflammation spectrum - not just good or bad

  Morsch, M., Lee, A. & Williams, K.

  1/01/21 → 31/12/23

  Project: Research

• Cuffless Blood Pressure Project (AtCor top-up scholarship - James Cox)

  Butlin, M. & Cox, J.

  2/10/20 → 30/05/23

  Project: Research

• Development of a dose-escalatable AAV delivery system for ALS gene therapies

  Chung, R., Lisowski, L. & Shi, B.

  1/10/20 → 30/09/22

  Project: Research

• Development of a TDP43-targeting gene therapy for ALS

  Chung, R., Lisowski, L., Walker, A. K., Rogers, M., Lee, A., Morsch, M. & Rayner, S.

  1/10/20 → 30/09/23

  Project: Research

• Lighthouse II: A confirmatory, randomized, placebo-controlled, group-sequential trial to investigate the efficacy and safety of Triumeq in patients with Amyotrophic Lateral Sclerosis (ALS): The Lighthouse II Trial

  Gold, J., Van den Berg, L. & Chapman, N.

  21/08/20 → 31/12/22

  Project: Research

• Is it the same? How does hypothalamus produce hypertension in acquired and inherited kidney disease vs. essential hypertension

  Phillips, J. K. & Hildreth, C.

  1/07/20 → 31/12/21

  Project: Research

• The link between threat perception, action, and cardiovascular risk

  McMullan, S.

  1/07/20 → 30/06/21

  Project: Research

• CRC-P round 9: Manufacturing consortium for cancer radioimmunotherapy

  Groth, A., Chandler, C., Adams, T., Walsh, B., Lengkeek, N., Chung, R., Gurney, H., Gillatt, D. & O'Meara, T.

  1/07/20 → 30/06/23

  Project: Research

• Multimodal Application Of Liquid Biopsies In Melanoma

  Rizos, H.

  30/06/20 → 30/06/23

  Project: Research

• The unexplored posttranslational modification (SUMOylation) of TDP-43 affects aggregate formation and localisation

  Morsch, M., Maurel, C., Lee, A., Vourc'H, P. & Chung, R.

  1/06/20 → 31/05/21

  Project: Research

• Biomarker-based identification of at-risk patients with COVID-19

  Guillemin, G. & Brew, B.

  1/06/20 → 31/12/21

  Project: Research

  File

• Clearance of TDP-43 by PROteolysis TArgeting Chimera (PROTAC) dual targeting to treat amyotrophic lateral sclerosis (ALS)

  Lee, A., Rayner, S., Martin, A., van Hummel, A., Morsch, M., Shi, B., Ke, Y., Ittner, L. & Chung, R.

  4/05/20 → 3/05/21

  Project: Research

• Collaborate and Cure: The Macquarie University Cancer Biobank

  Rizos, H.

  21/02/20 → 31/12/21

  Project: Research

• Medium-Chain Fatty Acids in Alzheimer's Disease Prevention

  Hillebrandt, H.

  6/01/20 → …

  Project: Research

• Loss-of-function of site-specific tau phosphorylation in Alzheimer's disease

  Ittner, A.

  1/01/20 → 31/12/24

  Project: Other

• The kynurenine pathway in neuroinflammatory diseases: Translation to prognostics and therapeutics

  Guillemin, G.

  1/01/20 → 31/12/24

  Project: Other

• CMNDR: Macquarie University Centre for Motor Neuron Disease Research

  Atkin, J., Blair, I., Rowe, D., Atkin, J., Chung, R., Guillemin, G., Laird, A., Lee, A., Morsch, M., Shi, B., Williams, K. & Yang, S.

  1/01/20 → 31/12/22

  Project: Other

• AU-ARROW: The AUstralian-Multidomain Approach to Reduce Dementia Risk by PrOtecting Brain Health With Lifestyle Intervention

  Shah, T., Botelho Dias, C. & Hillebrandt, H.

  1/01/20 → 31/12/22

  Project: Research

• COAD-P002: Examine the Effects of CocoMCT® on Clinical Factors Related to Health, Cognition, Quality of Life and Alzheimer's Disease: Double-Blind, Randomized Controlled Feeding Interventional Trial

  Botelho Dias, C. & Hillebrandt, H.

  1/01/20 → 31/12/23

  Project: Research

• The AUstralian-Multidomain Approach to Reduce Dementia Risk by PrOtecting Brain Health With Lifestyle Intervention

  Fuller, S., Shah, T., Martins, R., Botelho Dias, C., Sohrabi, H., Chatterjee, P. & Hillebrandt, H.

  1/01/20 → 30/09/24

  Project: Research

• Determining the molecular basis of amyotrophic lateral sclerosis

  Blair, I.

  1/01/20 → 31/12/24

  Project: Research

• Tackling Hospital Acquired Infections with Peptide Mimics

  Willcox, M. D. P., Kumar, N., Boyer, C., Wong, E., McKenzie, D., Suchowerska, N. & Vickery, K.

  1/01/20 → 31/12/23

  Project: Research

• HSIS

  Shah, T.

  1/01/20 → 31/07/21

  Project: Research

• Mechanisms of memory function involving site-specific tau phosphorylation

  Ittner, A. & Ittner, L.

  1/01/20 → 31/12/23

  Project: Other

• THE KYNURENINE PATHWAY IN NEUROINFLAMMATORY DISEASES: TRANSLATION TO PROGNOSTICS AND THERAPEUTICS

  Guillemin, G.

  30/11/19 → 29/11/24

  Project: Research

• Disease susceptibility, precision medicine and ALS

  Atkin, J., Blair, I., Rowe, D. & Lim, E.

  30/09/19 → 30/09/21

  Project: Other

• Biobanks, Big Data and ME: establishing a global registry and biobank in Australia to drive discovery of blood biomarkers.

  Fisher, P., Nicholl, H., Gooley, P., Lidbury, B. A., Guillemin, G. & Josev, E.

  1/07/19 → 31/12/24

  Project: Research

• Disease susceptibility, precision medicine and ALS

  Atkin, J. & Blair, I.

  1/07/19 → 1/07/21

  Project: Research

• Proteomic and molecular investigations into the diagnosis and progression of Motor Neuron Disease by the identification of biomarkers found in plasma

  Suddull, H., Chung, R. & Lee, A.

  1/07/19 → 30/06/22

  Project: Research

• The Michael Family Cancer Research Fund

  Rizos, H.

  27/05/19 → 31/12/21

  Project: Research

• Proteomic and Molecular Investigations into the Diagnosis and Progression of Motor Neuron Disease by the Identification of Biomarkers found in Plasma

  Suddull, H. & Chung, R.

  18/05/19 → 18/05/22

  Project: Research

• Novel Nanotechnology for the Delivery of Amyloid and Tau Hyperphosphorylation Targeting siRNA for Alzheimer’s Disease Therapy

  Shi, B., Chesworth, R., Wright, A., Ittner, L. & Karl, T.

  11/04/19 → 10/04/22

  Project: Research

• PANDIS (microorganisms & human diseases - Tick born diseases)

  Guillemin, G.

  15/03/19 → 31/12/23

  Project: Research

• Cannabidiol (CBD): A novel therapeutic for Alzheimer's disease.

  Karl, T., Garner, B., Ittner, A. & Ittner, L.

  2/01/19 → 31/12/21

  Project: Research

• Blood-Based Early Stage Colorectal Cancer Screening Saves Australian Lives

  Baker, M. S., Ahn, C., Nice, E., Chapuis, P., Parkinson, B. & Redmond, W.

  1/01/19 → 31/12/21

  Project: Research

• NHMRC - PG: Advanced computational fluid dynamic (CFD) technology to predict cerebrovascular aneurysm haemorrhage

  Sen, I., Morgan, M., Mao, Y., Di Ieva, A., Javadzadegan, A., Yang, Q. & Zhu, F.

  1/01/19 → 31/12/23

  Project: Research

• Neurotoxicity induced by environmental amino acids-mimetic toxins through inflammation

  Guillemin, G. & Mortaud, S.

  1/01/19 → 31/12/22

  Project: Research

  File

• Respiratory modulation: Role in the development of cardiovascular diseases

  Allen, A. M., McMullan, S., Bathgate, R. & Menuet, C.

  1/01/19 → 31/12/21

  Project: Research

• NBR: Defining the spatial and temporal regulation of neurite branching

  Fath, T., Gunning, P., Brandt, R., Klotzsch, E., Karl, T. & Delerue, F.

  18/12/18 → 17/12/21

  Project: Other

• Novel pathomechanisms and treatment approaches in Alzheimer's disease and related forms of dementia

  Ittner, L.

  1/12/18 → 31/12/22

  Project: Other

• Novel peripherally‐restricted cannabinoids to treat impaired neuromuscular synaptic transmission in myasthenia gravis and other neurological disorders

  Phillips, W. D., McGregor, I. S., Arnold, J., Bowen, M. T., Banister, S., Reddel, S. W., Odierna, L. & Morsch, M.

  20/11/18 → 31/12/22

  Project: Research

• NHMRC_CRE_USyd: Optimise Sleep in Brain Ageing and Neurodegeneration (CogSleep)

  Naismith, S., Grunstein, R. R., Lewis, S. J. G., Phillips, C. L., D'Rozario, A. L., Hoyos, C. M., Rajaratnam, S. W., Halliday, G., Martins, R., Lagopoulos, J., Saini, B., Gordon, C. J., Sutherland, G. T., Hickie, I., Kwok, J. B., Mowszowski, L., Soberats, M. C., Calvo, R., Adams, R. & Duffy, S.

  1/11/18 → 31/10/23

  Project: Research

• Frontotemporal dementia and motor neurodegenerative syndromes

  Halliday, G., Mattick, J. S., Hodges, J., Kiernan, M., Piguet, O., Kril, J. J., Ittner, L. & Kassiou, M.

  1/09/18 → 31/12/22

  Project: Research

• Snow Foundation Co-funded Fellowship: Determining the molecular pathogenesis of MND

  Morsch, M. & Chung, R.

  27/07/18 → 26/07/21

  Project: Other

• Snow Foundation Co-funded Fellow: Evaluating potential MND therapeutics in zebrafish models

  Laird, A. & Chung, R.

  27/07/18 → 26/07/21

  Project: Research