Research Output

2020

Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations

Konopka, A., Whelan, D. R., Jamali, M. S., Perri, E., Shahheydari, H., Toth, R. P., Parakh, S., Robinson, T., Cheong, A., Mehta, P., Vidal, M., Ragagnin, A. M. G., Khizhnyak, I., Jagaraj, C. J., Galper, J., Grima, N., Deva, A., Shadfar, S., Nicholson, G. A., Yang, S. & 6 others, Cutts, S. M., Horejsi, Z., Bell, T. D. M., Walker, A. K., Blair, I. P. & Atkin, J. D., 9 Sep 2020, In : Molecular Neurodegeneration. 15, 1, p. 1-28 28 p., 51.

Research output: Contribution to journalArticle

Open Access
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Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression

Achtyes, E., Keaton, S. A., Smart, L. A., Burmeister, A. R., Heilman, P. L., Krzyzanowski, S., Nagalla, M., Guillemin, G. J., Escobar Galvis, M. L., Lim, C. K., Muzik, M., Postolache, T. T., Leach, R. & Brundin, L., 1 Jan 2020, In : Brain, Behavior, and Immunity. 83, p. 239-247 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Influence of faculty organised revision sessions on anatomy assessment results

Štrkalj, G., El-Haddad, J., Hulme, A., Marhoff-Beard, S., Morfea, M. & Strkalj, M., Apr 2020, p. 262.

Research output: Contribution to conferencePoster

Interarm differences in brachial blood pressure and their effect on the derivation on central aortic blood pressure

Peebles, K. C., Tan, I., Cook, M. T. D., Theobald, D. A., Avolio, A. P. & Butlin, M., Jun 2020, In : Artery Research. 26, 2, p. 89-96 8 p.

Research output: Contribution to journalArticle

Open Access
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3 Downloads (Pure)

Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning

Liu, S., Shah, Z., Sav, A., Russo, C., Berkovsky, S., Qian, Y., Coiera, E. & Di Ieva, A., 7 May 2020, In : Scientific Reports. 10, p. 1-11 11 p., 7733.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)

Isotope metallomics approaches for medical research

Mahan, B., Chung, R. S., Pountney, D. L., Moynier, F. & Turner, S., Sep 2020, In : Cellular and Molecular Life Sciences. 77, 17, p. 3293-3309 17 p.

Research output: Contribution to journalReview article

Kynurenine and tetrahydrobiopterin pathways crosstalk in pain hypersensitivity

Staats Pires, A., Tan, V. X., Heng, B., Guillemin, G. J. & Latini, A., 24 Jun 2020, In : Frontiers in Neuroscience. 14, p. 1-12 12 p., 620.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

Kynurenine pathway modulation reverses the experimental autoimmune encephalomyelitis mouse disease progression

Sundaram, G., Lim, C. K., Brew, B. J. & Guillemin, G. J., 6 Jun 2020, In : Journal of Neuroinflammation. 17, 1, p. 1-14 14 p., 176.

Research output: Contribution to journalArticle

Open Access
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Longitudinal monitoring of ctDNA in patients with melanoma and brain metastases treated with immune checkpoint inhibitors

Lee, J. H., Menzies, A. M., Carlino, M. S., McEvoy, A. C., Sandhu, S., Weppler, A. M., Diefenbach, R. J., Dawson, S-J., Kefford, R. F., Millward, M. J., Al-Ogaili, Z., Tra, T., Gray, E. S., Wong, S. Q., Scolyer, R. A., Long, G. V. & Rizos, H., Aug 2020, In : Clinical Cancer Research. 26, 15, p. 4064-4071 8 p.

Research output: Contribution to journalArticle

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

Gillis, A., Gondin, A. B., Kliewer, A., Sanchez, J., Lim, H. D., Alamein, C., Manandhar, P., Santiago, M., Fritzwanker, S., Schmidel, F., Katte, T. A., Reekie, T., Grimsey, N. L., Kassiou, M., Kellam, B., Krasel, C., Halls, M. L., Connor, M., Lane, J. R., Schulz, S. & 2 others, Christie, M. J. & Canals, M., 31 Mar 2020, In : Science Signaling. 13, 625, p. 1-18 18 p., eaaz3140.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Measuring arterial stiffness in animal experimental studies

Butlin, M., Tan, I., Spronck, B. & Avolio, A. P., May 2020, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 5, p. 1068-1077 10 p.

Research output: Contribution to journalArticle

Open Access
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4 Downloads (Pure)

Metabolite profiling reveals predictive biomarkers and the absence of β-methyl amino-l-alanine in plasma from individuals diagnosed with amyotrophic lateral sclerosis

Bereman, M. S., Kirkwood, K. I., Sabaretnam, T., Furlong, S., Rowe, D. B., Guillemin, G. J., Mellinger, A. L. & Muddiman, D. C., 7 Aug 2020, In : Journal of Proteome Research. 19, 8, p. 3276-3285 10 p.

Research output: Contribution to journalArticle

Methylated circulating tumor DNA as a biomarker in cutaneous melanoma

Diefenbach, R. J., Lee, J. H. & Rizos, H., 31 Jul 2020, In : Melanoma Management. 3 p., 46.

Research output: Contribution to journalEditorial

Open Access

Multiplex detection of ctDNA mutations in plasma of colorectal cancer patients by PCR/SERS assay

Lyu, N., Rajendran, V. K., Diefenbach, R. J., Charles, K., Clarke, S. J., Engel, A., Sydney 1000 Colorectal Cancer Study Investigators, Rizos, H., Molloy, M. & Wang, Y., 25 Aug 2020, In : Nanotheranostics. 4, 4, p. 224-232 9 p.

Research output: Contribution to journalArticle

Open Access
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Nanomedicine-based immunotherapy for central nervous system disorders

Hanif, S., Muhammad, P., Chesworth, R., Rehman, F. U., Qian, R., Zheng, M. & Shi, B., Jul 2020, In : Acta Pharmacologica Sinica. 41, 7, p. 936-953 18 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Nanovehicles for co-delivery of anticancer agents

Zeinali, M., Abbaspour-Ravasjani, S., Ghorbani, M., Babazadeh, A., Soltanfam, T., Claudia Santos, A., Hamishehkar, H. & R. Hamblin, M., Aug 2020, In : Drug Discovery Today. 25, 8, p. 1416-1430 15 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Neuronal intranuclear inclusion disease is genetically heterogeneous

Chen, Z., Yan Yau, W., Jaunmuktane, Z., Tucci, A., Sivakumar, P., Gagliano Taliun, S. A., Turner, C., Efthymiou, S., Ibáñez, K., Sullivan, R., Bibi, F., Athanasiou-Fragkouli, A., Bourinaris, T., Zhang, D., Revesz, T., Lashley, T., DeTure, M., Dickson, D. W., Josephs, K. A., Gelpi, E. & 15 others, Kovacs, G. G., Halliday, G., Rowe, D. B., Blair, I., Tienari, P. J., Suomalainen, A., Fox, N. C., Wood, N. W., Lees, A. J., Haltia, M. J., Genomics England Research Consortium, Hardy, J., Ryten, M., Vandrovcova, J. & Houlden, H., 10 Aug 2020, In : Annals of Clinical and Translational Neurology. 10 p.

Research output: Contribution to journalArticle

Open Access

Nocturnal swallowing augments arousal intensity and arousal tachycardia

Burke, P. G. R., Carter, S. G., Knapman, F., Patti, J., Butlin, M., Gandevia, S. C., Butler, J. E., Eckert, D. J. & Bilston, L. E., 14 Apr 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 15, p. 8624-8632 9 p.

Research output: Contribution to journalArticle

Novel behavioural characteristics of male human P301S mutant tau transgenic mice: a model for tauopathy

Watt, G., Przybyla, M., Zak, V., van Eersel, J., Ittner, A., Ittner, L. & Karl, T., 1 Apr 2020, In : Neuroscience. 431, p. 166-175 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Novel immune biomarkers in complex regional pain syndrome

Russo, M. A., Georgius, P., Staats Pires, A., Heng, B., Allwright, M., Guennewig, B., Santarelli, D. M., Bailey, D., Fiore, N. T., Tan, V. X., Latini, A., Guillemin, G. J. & Austin, P. J., 16 Jul 2020, (Accepted/In press) In : Journal of Neuroimmunology. 347, p. 1-11 11 p., 577330.

Research output: Contribution to journalArticle

Observation and characterisation of macrophages in zebrafish liver

Cheng, D., Morsch, M., Shami, G. J., Chung, R. S. & Braet, F., 1 May 2020, In : Micron. 132, p. 1-12 12 p., 102851.

Research output: Contribution to journalArticle

Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature

Przybyla, M., Van Eersel, J., van Hummel, A., van der Hoven, J., Sabale, M., Harasta, A., Müller, J., Gajwani, M., Prikas, E., Mueller, T., Stevens, C. H., Power, J., Housley, G. D., Karl, T., Kassiou, M., Ke, Y. D., Ittner, A. & Ittner, L. M., Jun 2020, In : Brain. 143, 6, p. 1889-1904 16 p.

Research output: Contribution to journalArticle

Personality factors and cerebral glucose metabolism in community-dwelling older adults

Sohrabi, H. R., Goozee, K., Weinborn, M., Shen, K., Brown, B. M., Rainey-Smith, S. R., Salvado, O., Taddei, K., Bucks, R. S., Maruff, P., Laws, S. M., Lenzo, N., Laws, M., DeYoung, C., Speelman, C., Laske, C., Ames, D., Savage, G. & Martins, R. N., Jun 2020, In : Brain Structure and Function. 225, 5, p. 1511-1522 12 p.

Research output: Contribution to journalArticle

Phosphodiesterase-4 enzyme as a therapeutic target in neurological disorders

Bhat, A., Ray, B., Mahalakshmi, A. M., Tuladhar, S., Nandakumar, D. N., Srinivasan, M., Essa, M. M., Chidambaram, S. B., Guillemin, G. J. & Sakharkar, M. K., 14 Jul 2020, In : Pharmacological Research. 160, p. 1-18 18 p., 105078.

Research output: Contribution to journalReview article

Picolinic acid, a catabolite of tryptophan, has an anabolic effect on bone in vivo

Duque, G., Vidal, C., Li, W., Al Saedi, A., Khalil, M., Lim, C. K., Myers, D. E. & Guillemin, G. J., 6 Jul 2020, In : Journal of Bone and Mineral Research. 14 p.

Research output: Contribution to journalArticle

Plasma high density lipoprotein small subclass is reduced in Alzheimer's disease patients and correlates with cognitive performance

Pedrini, S., Hone, E., Gupta, V. B., James, I., Teimouri, E., Bush, A. I., Rowe, C. C., Villemagne, V. L., Ames, D., Masters, C. L., Rainey-Smith, S., Verdile, G., Sohrabi, H. R., Raida, M. R., Wenk, M. R., Taddei, K., Chatterjee, P., Martins, I., Laws, S. M., Martins, R. N. & 1 others, The AIBL Research Group, 24 Jul 2020, (Accepted/In press) In : Journal of Alzheimer's Disease. 12 p.

Research output: Contribution to journalArticle

Open Access

Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults

Chatterjee, P., Cheong, Y-J., Bhatnagar, A., Goozee, K., Wu, Y., McKay, M., Martins, I. J., Lim, W. L. F., Pedrini, S., Tegg, M., Villemagne, V., Asih, P. R., Dave, P., Shah, T. M., Dias, C. B., Fuller, S. J., Hillebrandt, H., Gupta, S., Hone, E., Taddei, K. & 4 others, Zetterberg, H., Blennow, K., Sohrabi, H. R. & Martins, R. N., 17 Jul 2020, In : Journal of Neurochemistry. 15 p.

Research output: Contribution to journalArticle

Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer's disease pathology

Ashraf, A., Ashton, N. J., Chatterjee, P., Goozee, K., Shen, K., Fripp, J., Ames, D., Rowe, C., Masters, C. L., Villemagne, V., Hye, A., Martins, R. N., So, P. W. & AIBL, 9 Jun 2020, In : Alzheimer's Research and Therapy. 12, 1, p. 1-13 13 p., 72.

Research output: Contribution to journalArticle

Open Access
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Possible role of tryptophan and melatonin in COVID-19

Essa, M. M., Hamdan, H., Chidambaram, S. B., Al-Balushi, B., Guillemin, G. J., Ojcius, D. M. & Qoronfleh, M. W., 2020, In : International Journal of Tryptophan Research. 13, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access
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Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease

Chatterjee, P., Fernando, M., Fernando, B., Dias, C. B., Shah, T., Silva, R., Williams, S., Pedrini, S., Hillebrandt, H., Goozee, K., Barin, E., Sohrabi, H. R., Garg, M., Cunnane, S. & Martins, R. N., 1 Mar 2020, In : Mechanisms of Ageing and Development. 186, p. 1-10 10 p., 111209.

Research output: Contribution to journalReview article

2 Citations (Scopus)

PreBötzinger complex neurons drive respiratory modulation of blood pressure and heart rate

Menuet, C., Connelly, A. A., Bassi, J. K., Melo, M. R., Le, S., Kamar, J., Kumar, N. N., McDougall, S. J., McMullan, S. & Allen, A. M., 15 Jun 2020, In : eLife. 9, p. 1-30 30 p., e57288.

Research output: Contribution to journalArticle

Open Access
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Preface

Diefenbach, R. J. & Fraefel, C., 1 Jan 2020, Herpes simplex virus: methods and protocols. Diefenbach, R. J. & Fraefel, C. (eds.). Second ed. New York, NY: Humana Press Inc., p. v-vi 2 p. (Methods in Molecular Biology; vol. 2060).

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript/introduction

Pressure dependency of retinal arterial pulse wave velocity in the rat

Rezaeian, M., Georgevsky, D., Golzan, S. M., Graham, S., Avolio, A. & Butlin, M., 1 Mar 2020, In : Artery Research. 26, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

Open Access
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4 Downloads (Pure)

Programmable enzymatic oxidation of tyrosine–lysine tetrapeptides

Sun, B., Ariawan, A. D., Warren, H., Goodchild, S. C., in het Panhuis, M., Ittner, L. M. & Martin, A. D., 21 Apr 2020, In : Journal of Materials Chemistry B. 8, 15, p. 3104-3112 9 p.

Research output: Contribution to journalArticle

Open Access

Protein nutrition in autism

Chidambaram, S. B., Bhat, A., Mahalakshmi, A. M., Ray, B., Tuladhar, S., Sushmitha, B. S., Saravanan, B., Thamilarasan, M., Thenmozhi, A. J., Essa, M. M., Guillemin, G. J. & Qoronfleh, M. W., 1 Jan 2020, Personalized food intervention and therapy for autism spectrum disorder management. Essa, M. M. & Qoronfleh, M. W. (eds.). Switzerland: Springer, p. 573-586 14 p. (Advances in Neurobiology; vol. 24).

Research output: Chapter in Book/Report/Conference proceedingChapter

Proteomic investigations into resistance in colorectal cancer

Cantor, D., Cheruku, H., Westacott, J., Shin, J-S., Mohamedali, A. & Ahn, S. B., 2 Jan 2020, In : Expert Review of Proteomics. 17, 1, p. 49-65 17 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Pullout force of minimally invasive surgical and open pedicle screws: a biomechanical cadaveric study

Matthews, P. G. M., Cadman, J., Tomka, J., Dabirrahmani, D., Appleyard, R. & Kam, A., Mar 2020, In : Journal of spine surgery (Hong Kong). 6, 1, p. 3-12 10 p.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)

Regional respiratory movement of the tongue is coordinated during wakefulness and is larger in severe obstructive sleep apnoea

Jugé, L., Knapman, F. L., Burke, P. G. R., Brown, E., Bosquillon de Frescheville, A. F., Gandevia, S. C., Eckert, D. J., Butler, J. E. & Bilston, L. E., 1 Feb 2020, In : Journal of Physiology. 598, 3, p. 581-597 17 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Relationship between arterial stiffness and chronic kidney disease in patients with primary hypertension

Zuo, J., Hu, Y., Chang, G., Chu, S. L., Tan, I., Butlin, M. & Avolio, A., Sep 2020, In : Journal of Human Hypertension. 34, 8, p. 577-585 9 p.

Research output: Contribution to journalArticle

Relationship between body mass index and arterial stiffness in a health assessment Chinese population

Tang, B., Luo, F., Zhao, J., Ma, J., Tan, I., Butlin, M., Avolio, A. & Zuo, J., 1 Jan 2020, In : Medicine. 99, 3, p. 1-5 5 p., e18793.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
4 Downloads (Pure)

Relationship between obesity phenotypes and cardiovascular risk in a Chinese cohort

Hu, Y., Zheng, S., Zhao, J., Tan, I., Butlin, M., Avolio, A. & Zuo, J., 1 Mar 2020, In : Artery Research. 26, 1, p. 34-41 8 p.

Research output: Contribution to journalArticle

Open Access
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Relationships between plasma lipids species, gender, risk factors, and Alzheimer’s disease

Lim, W. L. F., Huynh, K., Chatterjee, P., Martins, I., Jayawardana, K. S., Giles, C., Mellett, N. A., Laws, S. M., Bush, A. I., Rowe, C. C., Villemagne, V. L., Ames, D., Drew, B. G., Masters, C. L., Meikle, P. J., Martins, R. N. & The AIBL Research Group, 2020, In : Journal of Alzheimer's Disease. 76, 1, p. 303-315 13 p.

Research output: Contribution to journalArticle

Open Access
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SERS-based nanostrategy for rapid anemia diagnosis

Muhammad, P., Hanif, S., Yan, J., Rehman, F. U., Wang, J., Khan, M., Chung, R., Lee, A., Zheng, M., Wang, Y. & Shi, B., 21 Jan 2020, In : Nanoscale. 12, 3, p. 1948-1957 10 p.

Research output: Contribution to journalArticle

Serum hepcidin levels in cognitively normal older adults with high neocortical amyloid-β load

Chatterjee, P., Mohammadi, M., Goozee, K., Shah, T. M., Sohrabi, H. R., Dias, C. B., Shen, K., Asih, P. R., Dave, P., Pedrini, S., Ashton, N. J., Hye, A., Taddei, K., Lovejoy, D. B., Zetterberg, H., Blennow, K. & Martins, R. N., 2020, In : Journal of Alzheimer's Disease. 76, 1, p. 291-301 11 p.

Research output: Contribution to journalArticle

Open Access
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Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

Nabais, M. F., Lin, T., Benyamin, B., Williams, K. L., Garton, F. C., Vinkhuyzen, A. A. E., Zhang, F., Vallerga, C. L., Restuadi, R., Freydenzon, A., Zwamborn, R. A. J., Hop, P. J., Robinson, M. R., Gratten, J., Visscher, P. M., Hannon, E., Mill, J., Brown, M. A., Laing, N. G., Mather, K. A. & 17 others, Sachdev, P. S., Ngo, S. T., Steyn, F. J., Wallace, L., Henders, A. K., Needham, M., Veldink, J. H., Mathers, S., Nicholson, G., Rowe, D. B., Henderson, R. D., McCombe, P. A., Pamphlett, R., Yang, J., Blair, I. P., McRae, A. F. & Wray, N. R., 27 Feb 2020, In : npj Genomic Medicine. 5, 1, p. 1-9 9 p., 10.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
3 Downloads (Pure)

Single siRNA nanocapsules for effective siRNA brain delivery and glioblastoma treatment

Zou, Y., Sun, X., Wang, Y., Yan, C., Li, J., Zhang, D., Zheng, M., Chung, R. & Shi, B., Jun 2020, In : Advanced Materials. 32, 24, p. 1-9 9 p., 2000416.

Research output: Contribution to journalArticle