Research Output

2019

Association of NIPA1 repeat expansions with amyotrophic lateral sclerosis in a large international cohort

Tazelaar, G. H. P., Dekker, A. M., van Vugt, J. J. F. A., van der Spek, R. A., Westeneng, H-J., Kool, L. J. B. G., Kenna, K. P., van Rheenen, W., Pulit, S. L., McLaughlin, R. L., Sproviero, W., Iacoangeli, A., Hübers, A., Brenner, D., Morrison, K. E., Shaw, P. J., Shaw, C. E., Panadés, M. P., Mora Pardina, J. S., Glass, J. D. & 11 others, Hardiman, O., Al-Chalabi, A., van Damme, P., Robberecht, W., Landers, J. E., Ludolph, A. C., Weishaupt, J. H., van den Berg, L. H., Veldink, J. H., van Es, M. A. & Project MinE ALS Sequencing Consortium, 1 Feb 2019, In : Neurobiology of Aging. 74, p. 234.e9-234.e15 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Associations between local haemodynamics and carotid intraplaque haemorrhage with different stenosis severities: a preliminary study based on MRI and CFD

Dai, Y., Qian, Y., Zhang, M., Li, Y., Lv, P., Tang, X., Javadzadegan, A. & Lin, J., 1 Aug 2019, In : Journal of Clinical Neuroscience. 66, p. 220-225 6 p.

Research output: Contribution to journalArticle

A student’s guide to neural circuit tracing

Saleeba, C., Dempsey, B., Le, S., Goodchild, A. & McMullan, S., 27 Aug 2019, In : Frontiers in Neuroscience. 13, AUG, p. 1-19 19 p., 897.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
8 Downloads (Pure)

Autophagy modulation as a treatment of amyloid diseases

Mputhia, Z., Hone, E., Tripathi, T., Sargeant, T., Martins, R. & Bharadwaj, P., 16 Sep 2019, In : Molecules. 24, 18, p. 1-20 20 p., 3372.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
26 Downloads (Pure)

Autophagy promotes memory formation

Tripathi, T., Kalita, P., Martins, R. & Bharadwaj, P., 21 Aug 2019, In : ACS Chemical Neuroscience. 10, 8, p. 3337-3339 3 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Bacterial diversity of diabetic foot ulcers: current status and future prospectives

Sadeghpour Heravi, F., Zakrzewski, M., Vickery, K., Armstrong, D. G. & Hu, H., 10 Nov 2019, In : Journal of Clinical Medicine. 8, 11, p. 1-18 18 p., 1935.

Research output: Contribution to journalReview article

Open Access
File

Biofilm contamination of high-touched surfaces in intensive care units: epidemiology and potential impacts

Costa, D. M., Johani, K., Melo, D. S., Lopes, L. K. O., Lopes Lima, L. K. O., Tipple, A. F. V., Hu, H. & Vickery, K., 1 Apr 2019, In : Letters in Applied Microbiology. 68, 4, p. 269-276 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Bioreducible zinc(II)–dipicolylamine functionalized hyaluronic acid mediates safe siRNA delivery and effective glioblastoma RNAi therapy

Zheng, M., Yang, Z., Chen, S., Wu, H., Liu, Y., Wright, A., Lu, J-W., Xia, X., Lee, A., Zhang, J., Yin, H., Wang, Y., Ruan, W. & Liang, X-J., 22 Jan 2019, In : ACS Applied Bio Materials. 2, 1, p. 362-369 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Boswellia gum resin and essential oils: potential health benefits - an evidence based review

Rashan, L., Hakkim, F. L., Idrees, M., Essa, M. M., Velusamy, T., Al-Baloshi, M., Al-Balushi, B. S., Al Jabri, A., Al-Rizeiqi, M. H., Guillemin, G. & Abdo Hasson, S. S. A., 1 Apr 2019, In : International Journal of Nutrition, Pharmacology, Neurological Diseases. 9, 2, p. 53-71 19 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Brachial-ankle pulse wave velocity versus its stiffness index β-transformed value as risk marker for cardiovascular disease

Tomiyama, H., Ohkuma, T., Ninomiya, T., Nakano, H., Matsumoto, C., Avolio, A., Kohro, T., Higashi, Y., Maruhashi, T., Takase, B., Suzuki, T., Ishizu, T., Ueda, S., Yamazaki, T., Furumoto, T., Kario, K., Inoue, T., Koba, S., Takemoto, Y., Hano, T. & 9 others, Sata, M., Ishibashi, Y., Node, K., Maemura, K., Ohya, Y., Furukawa, T., Ito, H., Chikamori, T. & Yamashina, A., 17 Dec 2019, In : Journal of the American Heart Association. 8, 24, p. 1-12 12 p., e013004.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
6 Downloads (Pure)

Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells

Sachdev, S., Boyd, R., Grimsey, N. L., Santiago, M. & Connor, M., 25 Sep 2019, In : PeerJ. 2019, 9, p. 1-15 15 p., e7733.

Research output: Contribution to journalArticle

Open Access
File
10 Downloads (Pure)

Cannabichromene is a Cannabinoid CB2 receptor agonist

Udoh, M., Santiago, M., Devenish, S., McGregor, I. & Connor, M., Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4537-4547 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Cannabinoids for the treatment of spasticity

Nielsen, S., Murnion, B., Campbell, G., Young, H. & Hall, W., 1 Jun 2019, In : Developmental Medicine and Child Neurology. 61, 6, p. 631-638 8 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Cell culture substrates

Martin, A., Ittner, L. M. & Ke, Y. D., 21 Feb 2019, IPC No. C07K 5/ 10 A I, Patent No. WO2019033171, Priority date 16 Aug 2017, Priority No. AU20170903293

Research output: Patent

Open Access

Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer’s disease pathogenesis

Dhiman, K., Blennow, K., Zetterberg, H., Martins, R. N. & Gupta, V. B., 30 May 2019, In : Cellular and Molecular Life Sciences. 76, 10, p. 1833-1863 31 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos

Aksoy, Y. A., Nguyen, D. T., Chow, S., Chung, R. S., Guillemin, G. J., Cole, N. J. & Hesselson, D., 23 May 2019, In : Communications Biology. 2, p. 1-9 9 p., 198.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
33 Downloads (Pure)

Circulating cytokines predict immune-related toxicity in melanoma patients receiving anti-PD-1 based immunotherapy

Lim, S. Y., Lee, J. H., Nur Gide, T., Menzies, A. M., Guminski, A., Carlino, M. S., Breen, E., Yang, J. Y. H., Ghazanfar, S., Kefford, R. F., Scolyer, R. A., Long, G. V. & Rizos, H., Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1557-1563 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

CNS cell type-specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation

Ke, Y. D., Chan, G., Stefanoska, K., Au, C., Bi, M., Müller, J., Przybyla, M., Feiten, A., Prikas, E., Halliday, G. M., Piguet, O., Kiernan, M. C., Kassiou, M., Hodges, J. R., Loy, C. T., Mattick, J. S., Ittner, A., Kril, J. J., Sutherland, G. T. & Ittner, L. M., 20 Sep 2019, In : Journal of Biological Chemistry. 294, 38, p. 14149-14162 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Comparing DNA methylation profiles in saliva and intestinal mucosa

Hearn, N. L., Coleman, A. S., Ho, V., Chiu, C. L. & Lind, J. M., 28 Feb 2019, In : BMC Genomics. 20, 1, p. 1-9 9 p., 163.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
16 Downloads (Pure)

Complex design of surgical instruments as barrier for cleaning effectiveness, favouring biofilm formation

Lopes, L. K. O., Costa, D. M., Tipple, A. F. V., Watanabe, E., Castillo, R. B., Hu, H., Deva, A. K. & Vickery, K., Sep 2019, In : Journal of Hospital Infection. 103, 1, p. e53-e60 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Consent in spinal surgery: a survey of practice

Li Ching Ng, A., White, S. J., McRobb, L., Cyna, A. M., Seex, K. & Cartmill, J., 25 Oct 2019. 1 p.

Research output: Contribution to conferenceAbstract

16 Citations (Scopus)

Cuffless blood pressure monitoring and the advent of a new era in medicine and society

Avolio, A., Shirbani, F., Tan, I. & Butlin, M., 2019, The handbook of cuffless blood pressure monitoring: a practical guide for clinicians, researchers, and engineers. Sola, J. & Delgado-Gonzalo, R. (eds.). Switzerland: Springer Nature Switzerland AG, p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

CuMyl-4CN-BINACA is an efficacious and potent pro-convulsant synthetic cannabinoid receptor agonist

Kevin, R. C., Anderson, L., McGregor, I. S., Boyd, R., Manning, J. J., Glass, M., Connor, M. & Banister, S. D., 29 May 2019, In : Frontiers in Pharmacology. 10, MAY, p. 1-9 9 p., 595.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
2 Downloads (Pure)

Dark classics in Chemical Neuroscience: Δ 9 -tetrahydrocannabinol

Banister, S. D., Arnold, J. C., Connor, M., Glass, M. & Mcgregor, I. S., 15 May 2019, In : ACS Chemical Neuroscience. 10, 5, p. 2160-2175 16 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease

Hata, S., Omori, C., Kimura, A., Saito, H., Kimura, N., Gupta, V., Pedrini, S., Hone, E., Chatterjee, P., Taddei, K., Kasuga, K., Ikeuchi, T., Waragai, M., Nishimura, M., Hu, A., Nakaya, T., Meijer, L., Maeda, M., Yamamoto, T., Masters, C. L. & 6 others, Rowe, C. C., Ames, D., Yamamoto, K., Martins, R. N., Gandy, S. & Suzuki, T., 1 Jan 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 740-750 11 p.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)

Deepslice: a deep neural network for fully automatic alignment of histological sections

Carey, H., Redmond, W. & McMullan, S., 15 Nov 2019, p. 21. 1 p.

Research output: Contribution to conferenceAbstract

DeepSlice: a deep neural network for fully automatic alignment of histological sections

Carey, H., McMullan, S. & Redmond, W., 2 Dec 2019. 1 p.

Research output: Contribution to conferenceAbstract

Dendritic spines: revisiting the physiological role

Chidambaram, S. B., Rathipriya, A. G., Bolla, S. R., Bhat, A., Ray, B., Mahalakshmi, A. M., Manivasagam, T., Thenmozhi, A. J., Essa, M. M., Guillemin, G. J., Chandra, R. & Sakharkar, M. K., 8 Jun 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 92, p. 161-193 33 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Developmental expression of mutant PFN1 in motor neurons impacts neuronal growth and motor performance of young and adult mice

Brettle, M., Stefen, H., Djordjevic, A., Fok, S. Y. Y., Chan, J. W., van Hummel, A., van der Hoven, J., Przybyla, M., Volkerling, A., Ke, Y. D., Delerue, F., Ittner, L. M. & Fath, T., 27 Sep 2019, In : Frontiers in Molecular Neuroscience. 12, p. 1-12 12 p., 231.

Research output: Contribution to journalArticle

Open Access
File
4 Downloads (Pure)

Development of an innovative technology to segment luminal borders of intravascular ultrasound image sequences in a fully automated manner

Moshfegh, A., Javadzadegan, A., Mohammadi, M., Ravipudi, L., Cheng, S. & Martins, R., May 2019, In : Computers in Biology and Medicine. 108, p. 111-121 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Difficulty in removing biofilm from dry surfaces

Parvin, F., Hu, H., Whiteley, G. S., Glasbey, T. & Vickery, K., 1 Dec 2019, In : Journal of Hospital Infection. 103, 4, p. 465-467 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Distinct immune cell populations define response to anti-PD-1 monotherapy and anti-PD-1/anti-CTLA-4 combined therapy

Gide, T. N., Quek, C., Menzies, A. M., Tasker, A. T., Shang, P., Holst, J., Madore, J., Lim, S. Y., Velickovic, R., Wongchenko, M., Yan, Y., Lo, S., Carlino, M. S., Guminski, A., Saw, R. P. M., Pang, A., McGuire, H. M., Palendira, U., Thompson, J. F., Rizos, H. & 5 others, Silva, I. P. D., Batten, M., Scolyer, R. A., Long, G. V. & Wilmott, J. S., 11 Feb 2019, In : Cancer Cell. 35, 2, p. 238-255.e6 24 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Distinct molecular profiles and immunotherapy treatment outcomes of V600E and V600K BRAF-mutant melanoma

da Silva, I. P., Wang, K. Y. X., Wilmott, J. S., Holst, J., Carlino, M. S., Park, J. J., Quek, C., Wongchenko, M., Yan, Y., Mann, G., Johnson, D. B., McQuade, J. L., Rai, R., Kefford, R. F., Rizos, H., Scolyer, R. A., Yang, J. Y. H., Long, G. V. & Menzies, A. M., 15 Feb 2019, In : Clinical Cancer Research. 25, 4, p. 1272-1279 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Diurnal changes in central blood pressure and pulse pressure amplification in patients with obstructive sleep apnoea

Serinel, Y., Hoyos, C., Qasem, A., Yee, B. J., Grunstein, R. R., Wong, K. H. & Phillips, C. L., 1 May 2019, In : International Journal of Cardiology: Hypertension. 1, p. 1-8 8 p., 100002.

Research output: Contribution to journalArticle

Open Access
File
3 Downloads (Pure)
6 Citations (Scopus)

Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia

Kindler, J., Lim, C. K., Weickert, C. S., Boerrigter, D., Galletly, C., Liu, D., Jacobs, K. R., Balzan, R., Bruggemann, J., O’Donnell, M., Lenroot, R., Guillemin, G. J. & Weickert, T. W., 3 Apr 2019, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Easy conversion of cardio-ankle vascular index into CAVI0: influence of scale coefficients

Spronck, B., Mestanik, M., Tonhajzerova, I., Jurko, A., Tan, I., Butlin, M. & Avolio, A. P., 1 Sep 2019, In : Journal of Hypertension. 37, 9, p. 1913-1914 2 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
8 Downloads (Pure)

Effect of disinfectant formulation and organic soil on the efficacy of oxidizing disinfectants against biofilms

Chowdhury, D., Rahman, A., Hu, H., Jensen, S. O., Deva, A. K. & Vickery, K., 1 Sep 2019, In : Journal of Hospital Infection. 103, 1, p. e33-e41 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
89 Downloads (Pure)

Effect of extradural constriction on CSF flow in rat spinal cord

Berliner, J. A., Woodcock, T., Najafi, E., Hemley, S. J., Lam, M., Cheng, S., Bilston, L. E. & Stoodley, M. A., 26 Mar 2019, In : Fluids and Barriers of the CNS. 16, 1, 15 p., 7.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Effects of testosterone supplementation on separate cognitive domains in cognitively healthy older men: a meta-analysis of current randomized clinical trials

Tan, S., Sohrabi, H. R., Weinborn, M., Tegg, M., Bucks, R. S., Taddei, K., Carruthers, M. & Martins, R. N., 1 Nov 2019, In : American Journal of Geriatric Psychiatry. 27, 11, p. 1232-1246 15 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Emerging novel therapies in overcoming resistance to targeted therapy

Pinho, A. V., Lee, J. H. & Rizos, H., 2019, Current applications for overcoming resistance to targeted therapies. Szewczuk, M. R., Qorri, B. & Sambi, M. (eds.). Switzerland: Springer, Springer Nature, p. 223-258 36 p. (Resistance to Targeted Anti-Cancer Therapeutics; vol. 20).

Research output: Chapter in Book/Report/Conference proceedingChapter

Encapsulation of food ingredients by nanophytosomes

Babazadeh, A., Jafari, S. M. & Shi, B., 16 Aug 2019, Lipid-based nanostructures for food encapsulation purposes. Jafari, S. M. (ed.). Elsevier: Academic Press, Vol. 2. p. 405-443 39 p. (Nanoencapsulation in the Food Industry; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingChapter

Epithelial indoleamine 2,3-dioxygenase 1 modulates aryl hydrocarbon receptor and notch signaling to increase differentiation of secretory cells and alter mucus-associated microbiota

Alvarado, D. M., Chen, B., Iticovici, M., Thaker, A. I., Dai, N., VanDussen, K. L., Shaikh, N., Lim, C. K., Guillemin, G. J., Tarr, P. I. & Ciorba, M. A., 1 Oct 2019, In : Gastroenterology. 157, 4, p. 1093-1108 27 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

Farhan, S. M. K., Howrigan, D. P., Abbott, L. E., Klim, J. R., Topp, S. D., Byrnes, A. E., Churchhouse, C., Phatnani, H., Smith, B. N., Rampersaud, E., Wu, G., Wuu, J., Shatunov, A., Iacoangeli, A., Al Khleifat, A., Mordes, D. A., Ghosh, S., ALSGENS Consortium, FALS Consortium, Project MinE Consortium & 19 others, CReATe Consortium, Eggan, K., Rademakers, R., McCauley, J. L., Schüle, R., Züchner, S., Benatar, M., Taylor, J. P., Nalls, M., Gotkine, M., Shaw, P. J., Morrison, K. E., Al-Chalabi, A., Traynor, B., Shaw, C. E., Goldstein, D. B., Harms, M. B., Daly, M. J. & Neale, B. M., 1 Dec 2019, In : Nature Neuroscience. 22, 12, p. 1966-1974 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V

Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S., Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., Robberecht, W. & 2 others, Rousseau, F. & Schymkowitz, J., 31 Dec 2019, In : Protein Engineering, Design and Selection. 32, 10, p. 443-457 15 p.

Research output: Contribution to journalArticle

Extracellular vesicles released by glioblastoma cells stimulate normal astrocytes to acquire a tumor-supportive phenotype via p53 and MYC signaling pathways

Hallal, S., Mallawaaratchy, D. M., Wei, H., Ebrahimkhani, S., Stringer, B. W., Day, B. W., Boyd, A. W., Guillemin, G. J., Buckland, M. E. & Kaufman, K. L., 1 Jun 2019, In : Molecular Neurobiology. 56, 6, p. 4566-4581 16 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
46 Downloads (Pure)

Eye clinic as a potential site to measure blood pressure

Adji, A., 1 Jan 2019, In : American Journal of Hypertension. 32, 1, p. 12-14 3 p.

Research output: Contribution to journalArticle

First nondiscriminating translocator protein ligands produced from a carbazole scaffold

Cheng, H. W. A., Sokias, R., Werry, E. L., Ittner, L. M., Reekie, T. A., Du, J., Gao, Q., Hibbs, D. E. & Kassiou, M., 12 Sep 2019, In : Journal of Medicinal Chemistry. 62, 17, p. 8235-8248 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)