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2018

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., Ge, Y., Gunawardena, J., Hendrickson, R. C., Hergenrother, P. J., Huber, C. G., Ivanov, A. R., Jensen, O. N., Jewett, M. C., Kelleher, N. L., Kiessling, L. L. & 33 others, Krogan, N. J., Larsen, M. R., Loo, J. A., Ogorzalek Loo, R. R., Lundberg, E., Maccoss, M. J., Mallick, P., Mootha, V. K., Mrksich, M., Muir, T. W., Patrie, S. M., Pesavento, J. J., Pitteri, S. J., Rodriguez, H., Saghatelian, A., Sandoval, W., Schlüter, H., Sechi, S., Slavoff, S. A., Smith, L. M., Snyder, M. P., Thomas, P. M., Uhlén, M., Van Eyk, J. E., Vidal, M., Walt, D. R., White, F. M., Williams, E. R., Wohlschlager, T., Wysocki, V. H., Yates, N. A., Young, N. L. & Zhang, B., 14 Feb 2018, In : Nature Chemical Biology. 14, 3, p. 206-214 9 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Hydroxyl-functional groups on graphene trigger the targeted delivery of antitumor drugs

Lin, M., Shan, S., Liu, P., Ma, L., Huang, L., Yang, M., Lawson, T., Wang, Z., Huang, Z., Shi, B., Yan, L. & Liu, Y., 1 Aug 2018, In : Journal of Biomedical Nanotechnology. 14, 8, p. 1420-1429 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hypochlorous acid versus povidone-iodine containing irrigants: Which antiseptic is more effective for breast implant pocket irrigation?

Hu, H., Sleiman, J., Johani, K. & Vickery, K., 13 Jun 2018, In : Aesthetic Surgery Journal. 38, 7, p. 723-727 5 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Identity centrality moderates the relationship between acceptance of group-based stressors and well-being

Crane, M. F., Louis, W., Phillips, J. K., Amiot, C. & Steffens, N., Oct 2018, In : European Journal of Social Psychology. 48, 6, p. 866-882 17 p.

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Influence of dietary nitrate supplementation on lung function and exercise gas exchange in COPD patients

Behnia, M., Wheatley, C. M., Avolio, A. & Johnson, B. D., 1 Jun 2018, In : Nitric Oxide - Biology and Chemistry. 76, p. 53-61 9 p.

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7 Citations (Scopus)
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Inhibiting the kynurenine pathway in spinal cord injury: multiple therapeutic potentials?

Jacobs, K. R. & Lovejoy, D. B., 1 Dec 2018, In : Neural Regeneration Research. 13, 12, p. 2073-2076 4 p.

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4 Citations (Scopus)
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Interferon signaling is frequently downregulated in melanoma

Alavi, S., Stewart, A. J., Kefford, R. F., Lim, S. Y., Shklovskaya, E. & Rizos, H., 2018, In : Frontiers in Immunology. 9, p. 1-12 12 p., 1414.

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5 Citations (Scopus)
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Isolated systolic hypertension in the young: a position paper endorsed by the European Society of Hypertension

Palatini, P., Rosei, E. A., Avolio, A., Bilo, G., Casiglia, E., Ghiadoni, L., Giannattasio, C., Grassi, G., Jelakovich, B., Julius, S., Mancia, G., McEniery, C. M., O'Rourke, M. F., Parati, G., Pauletto, P., Pucci, G., Saladini, F., Strazzullo, P., Tsioufis, K., Wilkinson, I. B. & 1 others, Zanchetti, A., 1 Jun 2018, In : Journal of Hypertension. 36, 6, p. 1222-1236 15 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Lactulose: properties, techno-functional food applications, and food grade delivery system

Nooshkam, M., Babazadeh, A. & Jooyandeh, H., 1 Oct 2018, In : Trends in Food Science and Technology. 80, p. 23-34 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model

Haslinger, D., Waltes, R., Yousaf, A., Lindlar, S., Schneider, I., Lim, C. K., Tsai, M. M., Garvalov, B. K., Acker-Palmer, A., Krezdorn, N., Rotter, B., Acker, T., Guillemin, G. J., Fulda, S., Freitag, C. M. & Chiocchetti, A. G., 6 Nov 2018, In : Molecular autism. 9, 1, p. 1-17 17 p., 56.

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4 Citations (Scopus)
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L-Serine-mediated neuroprotection includes the upregulation of the ER stress chaperone protein disulfide isomerase (PDI)

Dunlop, R. A., Powell, J. T., Metcalf, J. S., Guillemin, G. J. & Cox, P. A., 1 Jan 2018, In : Neurotoxicity Research. 33, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Mechanisms and effects posed by neurotoxic products of cyanobacteria/microbial eukaryotes/dinoflagellates in algae blooms: a review

Mello, F. D., Braidy, N., Marçal, H., Guillemin, G., Nabavi, S. M. & Neilan, B. A., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 153-167 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Mechanisms of L-serine neuroprotection in vitro include ER proteostasis regulation

Dunlop, R. A., Powell, J., Guillemin, G. J. & Cox, P. A., 1 Jan 2018, In : Neurotoxicity Research. 33, 1, p. 123-132 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
5 Citations (Scopus)

Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

Rainey-Smith, S. R., Gu, Y., Gardener, S. L., Doecke, J. D., Villemagne, V. L., Brown, B. M., Taddei, K., Laws, S. M., Sohrabi, H. R., Weinborn, M., Ames, D., Fowler, C., Macaulay, S. L., Maruff, P., Masters, C. L., Salvado, O., Rowe, C. C., Scarmeas, N. & Martins, R. N., 30 Oct 2018, In : Translational Psychiatry. 8, 1, p. 1-7 7 p., 238.

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9 Citations (Scopus)
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Metastasis-specific patterns of response and progression with anti-PD-1 treatment in metastatic melanoma

Lee, J. H. J., Lyle, M., Menzies, A. M., Chan, M. M. K., Lo, S., Clements, A., Carlino, M. S., Kefford, R. F. & Long, G. V., 1 May 2018, In : Pigment Cell and Melanoma Research. 31, 3, p. 404-410 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: segmentation

Berg, P., Voß, S., Saalfeld, S., Janiga, G., Bergersen, A. W., Valen-Sendstad, K., Bruening, J., Goubergrits, L., Spuler, A., Cancelliere, N. M., Steinman, D. A., Pereira, V. M., Chiu, T. L., Tsang, A. C. O., Chung, B. J., Cebral, J. R., Cito, S., Pallarès, J., Copelli, G., Csippa, B. & 31 others, Paál, G., Fujimura, S., Takao, H., Hodis, S., Hille, G., Karmonik, C., Elias, S., Kellermann, K., Khan, M. O., Marsden, A. L., Morales, H. G., Piskin, S., Finol, E. A., Pravdivtseva, M., Rajabzadeh-Oghaz, H., Paliwal, N., Meng, H., Seshadhri, S., Howard, M., Shojima, M., Sugiyama, S., Niizuma, K., Sindeev, S., Frolov, S., Wagner, T., Brawanski, A., Qian, Y., Wu, Y. A., Carlson, K. D., Dragomir-Daescu, D. & Beuing, O., 15 Dec 2018, In : Cardiovascular Engineering and Technology. 9, 4, p. 565-581 17 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Myxobacterial natural products: an under-valued source of products for drug discovery for neurological disorders

Dehhaghi, M., Mohammadipanah, F. & Guillemin, G. J., May 2018, In : NeuroToxicology. 66, p. 195-203 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Naringenin decreases α-synuclein expression and neuroinflammation in MPTP-induced Parkinson’s disease model in mice

Mani, S., Sekar, S., Barathidasan, R., Manivasagam, T., Thenmozhi, A. J., Sevanan, M., Chidambaram, S. B., Essa, M. M., Guillemin, G. J. & Sakharkar, M. K., Apr 2018, In : Neurotoxicity Research. 33, 3, p. 656-670 15 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease

Acosta, J. R., Watchon, M., Yuan, K. C., Fifita, J. A., Svahn, A. J., Don, E. K., Winnick, C. G., Blair, I. P., Nicholson, G. A., Cole, N. J., Goldsbury, C. & Laird, A. S., Oct 2018, In : Biology Open. 7, 10, p. 1-7 7 p., bio036475.

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2 Citations (Scopus)
14 Downloads (Pure)

Neuronal MAP kinase p38α inhibits c-Jun N-terminal kinase to modulate anxiety-related behaviour

Stefanoska, K., Bertz, J., Volkerling, A. M., van der Hoven, J., Ittner, L. M. & Ittner, A., 1 Dec 2018, In : Scientific Reports. 8, 1, p. 1-12 12 p., 14296.

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10 Citations (Scopus)
11 Downloads (Pure)

Neuroprotective effect of acute prior inflammation with lipopolysaccharide for adult male rat facial motoneurones

Katharesan, V., Deery, S. & Johnson, I. P., 1 Oct 2018, In : Brain Research. 1696, p. 56-62 7 p.

Research output: Contribution to journalArticle

Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease

Ahmad Rather, M., Justin Thenmozhi, A., Manivasagam, T., Dhivya Bharathi, M., Mohamed Essa, M. & Guillemin, G. J., 1 Jan 2018, In : Frontiers in bioscience (Scholar edition). 10, p. 262-275 14 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Neurotoxicity of the cyanotoxin BMAA through axonal degeneration and intercellular spreading

Tan, V. X., Lassus, B., Lim, C. K., Tixador, P., Courte, J., Bessede, A., Guillemin, G. J. & Peyrin, J. M., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 62-75 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nigrostriatal pathology with reduced astrocytes in LRRK2 S910/S935 phosphorylation deficient knockin mice

Zhao, Y., Keshiya, S., Atashrazm, F., Gao, J., Ittner, L. M., Alessi, D. R., Halliday, G. M., Fu, Y. & Dzamko, N., 1 Dec 2018, In : Neurobiology of Disease. 120, p. 76-87 12 p.

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6 Citations (Scopus)
5 Downloads (Pure)

Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target

Ma, L., Chin, Y. K. Y., Dekan, Z., Herzig, V., Chow, C. Y., Heighway, J., Lam, S. W., Guillemin, G. J., Alewood, P. F. & King, G. F., 1 Dec 2018, In : Biochemical Pharmacology. 158, p. 60-72 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

N-point moving average: a special generalized transfer function method for estimation of central aortic blood pressure

Xiao, H., Butlin, M., Qasem, A., Tan, I., Li, D. & Avolio, A. P., 1 Jun 2018, In : IEEE Transactions on Biomedical Engineering. 65, 6, p. 1226-1234 9 p., 2710622.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons

Svahn, A. J., Don, E. K., Badrock, A. P., Cole, N. J., Graeber, M. B., Yerbury, J. J., Chung, R. & Morsch, M., Sep 2018, In : Acta Neuropathologica. 136, 3, p. 445-459 15 p.

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12 Citations (Scopus)
29 Downloads (Pure)

Numerical simulation of aneurysmal haemodynamics with calibrated porous-medium models of flow-diverting stents

Li, Y., Zhang, M., Verrelli, D. I., Chong, W., Ohta, M. & Qian, Y., 26 Oct 2018, In : Journal of Biomechanics. 80, p. 88-94 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Oligomeric and fibrillar amyloid beta 42 induce platelet aggregation partially through GPVI

Elaskalani, O., Khan, I., Morici, M., Matthysen, C., Sabale, M., Martins, R. N., Verdile, G. & Metharom, P., 19 May 2018, In : Platelets. 29, 4, p. 415-420 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma

Irvine, M., Stewart, A., Pedersen, B., Boyd, S., Kefford, R. & Rizos, H., 1 Sep 2018, In : Oncogenesis. 7, 9, p. 1-11 11 p., 72.

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10 Citations (Scopus)
15 Downloads (Pure)

Osmoregulation in polycystic kidney disease: relationship with cystogenesis and hypertension

Underwood, C. F., Phillips, J. K. & Hildreth, C. M., 1 Jun 2018, In : Annals of Nutrition and Metabolism. 72, suppl 2, p. 33-38 6 p.

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Open Access
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1 Citation (Scopus)
4 Downloads (Pure)

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D. & 2 others, Molloy, M. P. & Chung, R. S., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

PAX3: a molecule with oncogenic or tumor suppressor function is involved in cancer

Arasu, A., Murugan, S., Essa, M. M., Velusamy, T. & Guillemin, G. J., 16 Aug 2018, In : BioMed Research International. 2018, p. 1-12 12 p., 1095459.

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Pediatric reference values for arterial stiffness parameters cardio-ankle vascular index and CAVI0

Jurko, T., Mestanik, M., Jurko, A., Spronck, B., Avolio, A., Mestanikova, A., Sekaninova, N. & Tonhajzerova, I., 1 Nov 2018, In : Journal of the American Society of Hypertension. 12, 11, p. e35-e43 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Peptide nanofiber substrates for long-term culturing of primary neurons

Martin, A. D., Chua, S. W., Au, C. G., Stefen, H., Przybyla, M., Lin, Y., Bertz, J., Thordarson, P., Fath, T., Ke, Y. D. & Ittner, L. M., 1 Aug 2018, In : ACS Applied Materials and Interfaces. 10, 30, p. 25127-25134 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Perinatal exposure to the cyanotoxin β-N-méthylamino-L-alanine (BMAA) results in long-lasting behavioral changes in offspring: potential involvement of DNA damage and oxidative stress

Laugeray, A., Oummadi, A., Jourdain, C., Feat, J., Meyer-Dilhet, G., Menuet, A., Plé, K., Gay, M., Routier, S., Mortaud, S. & Guillemin, G. J., Jan 2018, In : Neurotoxicity Research. 33, 1, p. 87-112 26 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Personality characteristics are independently associated with prospective memory in the laboratory, and in daily life, among older adults

McCabe, K. A., Woods, S. P., Weinborn, M., Sohrabi, H., Rainey-Smith, S., Brown, B. M., Gardener, S. L., Taddei, K. & Martins, R. N., 1 Oct 2018, In : Journal of Research in Personality. 76, p. 32-37 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Phototracking vaccinia virus transport reveals dynamics of cytoplasmic dispersal and a requirement for A36R and F12L for exit from the site of wrapping

Lynn, H., Howell, L. M., Diefenbach, R. J. & Newsome, T. P., 24 Jul 2018, In : Viruses. 10, 8, p. 1-18 18 p., 390.

Research output: Contribution to journalArticle

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Physical activity in preventing Alzheimer’s disease and cognitive decline: a narrative review

Brini, S., Sohrabi, H. R., Peiffer, J. J., Karrasch, M., Hämäläinen, H., Martins, R. N. & Fairchild, T. J., Jan 2018, In : Sports Medicine. 48, 1, p. 29-44 16 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Physicochemical and aerosolization assessment of inhalable spray dried fluconazole powder

Hamishehkar, H., Pourtahmaseb, M., Babazadeh, A. & Alipour, S., 1 Sep 2018, In : Pharmaceutical Sciences. 24, 3, p. 219-226 8 p.

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Progress on identifying and characterizing the human proteome: 2018 metrics from the HUPO Human Proteome Project

Omenn, G. S., Lane, L., Overall, C. M., Corrales, F. J., Schwenk, J. M., Paik, Y. K., Van Eyk, J. E., Liu, S., Snyder, M., Baker, M. S. & Deutsch, E. W., 7 Dec 2018, In : Journal of Proteome Research. 17, 12, p. 4031-4041 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Project MinE: study design and pilot analyses of a large-scale whole-genome sequencing study in amyotrophic lateral sclerosis

Project MinE ALS Sequencing Consortium, Oct 2018, In : European Journal of Human Genetics. 26, 10, p. 1537-1546 10 p.

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28 Citations (Scopus)
8 Downloads (Pure)

Pulsatile interaction between the macro-vasculature and micro-vasculature: proof-of-concept among patients with type 2 diabetes

Climie, R. E. D., Picone, D. S., Blackwood, S., Keel, S. E., Qasem, A., Rattigan, S. & Sharman, J. E., 1 Nov 2018, In : European Journal of Applied Physiology. 118, 11, p. 2455-2463 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Pulsatile stretch as a novel modulator of amyloid precursor protein processing and associated inflammatory markers in human cerebral endothelial cells

Gangoda, S. V. S., Avadhanam, B., Jufri, N. F., Sohn, E. H., Butlin, M., Gupta, V., Chung, R. & Avolio, A. P., 26 Jan 2018, In : Scientific Reports. 8, 1, p. 1-10 10 p., 1689.

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Open Access
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13 Citations (Scopus)
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7 Citations (Scopus)

Quantitative assessment of changes in hemodynamics of the internal carotid artery after bypass surgery for moyamoya disease

Zhu, F., Qian, Y., Xu, B., Gu, Y., Karunanithi, K., Zhu, W., Chen, L., Mao, Y. & Morgan, M. K., Sep 2018, In : Journal of Neurosurgery. 129, 3, p. 677-683 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Rational surface design of upconversion nanoparticles with polyethylenimine (PEI) coating for biomedical applications: better safe than brighter?

Guller, A. E., Nadort, A., Generalova, A. N., Khaydukov, E. V., Nechaev, A. V., Kornienko, I. A., Petersen, E. V., Liang, L., Shekhter, A. B., Qian, Y., Goldys, E. M. & Zvyagin, A. V., 10 Sep 2018, In : ACS Biomaterials Science and Engineering. 4, 9, p. 3143-3153 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

Formella, I., Svahn, A. J., Radford, R. A. W., Don, E. K., Cole, N. J., Hogan, A., Lee, A., Chung, R. S. & Morsch, M., 1 Oct 2018, In : Redox Biology. 19, p. 226-234 9 p.

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7 Citations (Scopus)
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Regional cardiac sympathetic nervous system evaluation using 123I-mIBG SPECT in patients with heart failure

Iqbal, B., Currie, G. & Kiat, H., Dec 2018, In : Journal of Medical Imaging and Radiation Sciences. 49, 4, p. 397-405 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)