Projects per year
Personal profile
Biography
Adam Martin completed his PhD at UWA in 2011 with Professor Colin Raston in the area of supramolecular chemistry. He then commenced a postdoctoral position at the University of Nottingham with Professor Martin Schröder synthesising novel ligands for new metal organic frameworks. In 2013 he moved to the University of New South Wales to work with Professor Pall Thordarson on deciphering the desgin rules in short peptide hydrogels. In 2016 he was awarded an NHMRC-ARC Dementia Research Fellowship to use these scaffolds for culturing sensitive primary neurons, thus gaining insights into the early stages of Alzheimer's Disease. He was promoted to Lecturer in early 2018 and in 2019 he commenced a position at Macquarie University as Leader of the Peptides and Proteins Group within the Dementia Research Centre.
Research interests
Through his research, Adam has established a number of structure-property relationships for short, self-assembling peptides. He has shown that control over the peptide sequence and N-terminus can be used to tune the chemical and mechanical properties of resultant hydrogels. Adam is now focused on translating this knoweldge to the rational design of biocompatible hydrogel scaffolds for tissue engineering to support various cell types, including sensitive primary neurons. Current projects include:
- Devleopment of 3D neuronal cell culture scaffolds for insights into neurodegenerative disease.
- Functionalisation of hydrogels with ECM-ligating peptides for active capture of macromolecules.
- Self-assemlbimg short peptides as novel transfection reagents.
- Controlling temporal hydrogel scaffold degradation for biologically relevant cell profiling.
Education/Academic qualification
Supramolecular Chemistry, PhD, Self-assembly of phosphonic acid calixarenes, The University of Western Australia
Award Date: 1 Aug 2011
External positions
Adjunct Lecturer, The University of New South Wales
2 Jan 2019 → …
Lecturer, The University of New South Wales
1 Jan 2018 → 31 Dec 2018
Research Fellow, The University of New South Wales
1 Feb 2016 → 31 Dec 2018
Postdoctoral Research Associate, The University of New South Wales
1 Sept 2013 → 31 Jan 2016
Postdoctoral Research Associate, University of Nottingham - UK
14 Nov 2011 → 16 Aug 2013
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Collaborations and top research areas from the last five years
Projects
- 4 Finished
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Targeting pathogenic TAR DNA-binding protein 43 to treat frontotemporal dementia and motor neuron disease
Ke, Y., van Hummel, A., Ariawan, D., Ittner, L. & Martin, A.
1/01/21 → 31/12/23
Project: Research
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Clearance of TDP-43 by PROteolysis TArgeting Chimera (PROTAC) dual targeting to treat amyotrophic lateral sclerosis (ALS)
Lee, A., Rayner, S., Martin, A., van Hummel, A., Morsch, M., Shi, B., Ke, Y., Ittner, L. & Chung, R.
4/05/20 → 3/05/21
Project: Research
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Hydrogels with intrinsic antibacterial activity prepared from naphthyl anthranilamide (NaA) capped peptide mimics
Aldilla, V. R., Chen, R., Kuppusamy, R., Chakraborty, S., Willcox, M. D. P., Black, D. S. C., Thordarson, P., Martin, A. D. & Kumar, N., 23 Dec 2022, In: Scientific Reports. 12, 1, p. 1-12 12 p., 22259.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)66 Downloads (Pure) -
Lanthanide-based β-tricalcium phosphate upconversion nanoparticles as an effective theranostic nonviral vectors for image-guided gene therapy
Silva, F. R. O., Lima, N. B., Bellini, M. H., Teixeira, L. F. S., Du, E. Y., Jamshidi, N., Gooding, J., Martin, A. D., Macmillan, A., Marquis, C. P. & Thordarson, P., 2022, In: Nanotheranostics. 6, 3, p. 306-321 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)20 Downloads (Pure) -
Recent progress in synthetic self-adjuvanting vaccine development
Ariawan, D., van Eersel, J., Martin, A. D., Ke, Y. D. & Ittner, L. M., 26 Jul 2022, In: Biomaterials Science. 10, 15, p. 4037-4057 21 p.Research output: Contribution to journal › Review article › peer-review
5 Citations (Scopus) -
A dendronised polymer architecture breaks the conventional inverse relationship between porosity and mechanical properties of hydrogels
Evans, C. W., Ho, D., Lee, P. K. H., Martin, A. D., Chin, I. L., Wei, Z., Li, H., Atkin, R., Choi, Y. S., Norret, M., Thordarson, P. & Iyer, K. S., 18 Jan 2021, In: Chemical Communications. 57, 6, p. 773-776 4 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Global root traits (GRooT) database
Guerrero-Ramirez, N. R., Mommer, L., Freschet, G. T., Iversen, C. M., McCormack, M. L., Kattge, J., Poorter, H., van der Plas, F., Bergmann, J., Kuyper, T. W., York, L. M., Bruelheide, H., Laughlin, D. C., Meier, I. C., Roumet, C., Semchenko, M., Sweeney, C. J., van Ruijven, J., Valverde-Barrantes, O. J., Aubin, I., & 29 others , Jan 2021, In: Global Ecology and Biogeography: a journal of macroecology. 30, 1, p. 25-37 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile97 Citations (Scopus)26 Downloads (Pure)