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Personal profile

Biography

My career to date has focused on medical research and education in the tertiary sector, developing and managing ongoing relationships with key opinion leaders between academia, industry and community to foster opportunities for correspondence and exchange.

 

My passion is educating, supervising and inspiring students to drive change and their own personal growth. Every student has their own unique and valuable life experiences and my goal is to adapt my techniques to ensure each student achieves a better understanding of scientific and medical research to achieve positive outcomes. I aim to provide students with a set of tools and principles that allow them to critically think and analyse complex issues to become students and contributors for the community.

 

My research interests focus on understanding the mechanisms of cellular survival upon stress, and its role in biological processes that manifest into human diseases such as neurological disorders. My research uses proteomics to characterise post-translational modifications (including phosphorylation, ubiquitination, and glycosylation) to understand their role in cellular processes. High-throughput analyses of post-translational modifications is becoming more widespread due to their growing importance in biology, which puts me in a unique position to use my expertise to address this need.

Education/Academic qualification

Doctor of Philosophy

4 Sep 200622 Sep 2010

Masters of Science (Biotechnology)

1 Mar 200530 Jun 2006

Bachelor of Science, University of Sydney

1 Mar 200215 Dec 2004

External positions

NIH Heart Lung Blood Institute (NHLBI) Postdoctoral Fellow, Johns Hopkins School of Medicine

1 Jul 20111 Nov 2013

Scientific Technician, New York University School of Medicine

1 Jul 20101 Jun 2011

Fingerprint Dive into the research topics where Albert Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Ubiquitin-Protein Ligases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2021

The role of mutant CYLD in frontotemporal dementia and motor neuron disease

Blair, I., Dobson-Stone, C., Kwok, J. B., Atkin, J., Ooi, L., Ittner, A., Lee, A., Mather, K. A., Thompson, E. & Burgio, G.

1/01/1831/12/21

Project: Research

Research Outputs 2006 2020

Bioreducible zinc(II)–dipicolylamine functionalized hyaluronic acid mediates safe siRNA delivery and effective glioblastoma RNAi therapy

Zheng, M., Yang, Z., Chen, S., Wu, H., Liu, Y., Wright, A., Lu, J-W., Xia, X., Lee, A., Zhang, J., Yin, H., Wang, Y., Ruan, W. & Liang, X-J., 22 Jan 2019, In : ACS Applied Bio Materials. 2, 1, p. 362-369 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Hyaluronic Acid
Glioblastoma
RNA Interference
Small Interfering RNA
Nanomedicine

Central metal-derived co-assembly of biomimetic GdTPP/ZnTPP porphyrin nanocomposites for enhanced dual-modal imaging-guided photodynamic therapy

Wang, J., Wang, Z., Zhong, Y., Zou, Y., Wang, C., Wu, H., Lee, A., Yang, W., Wang, X., Liu, Y., Zhang, D., Yan, J., Hao, M., Zheng, M., Chung, R., Bai, F. & Shi, B., 24 Oct 2019, (Accepted/In press) In : Biomaterials. 229, 13 p., 119576.

Research output: Contribution to journalArticleResearchpeer-review

Nanocomposites
Biomimetics
Photodynamic therapy
Porphyrins
Photochemotherapy

Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery

Wang, G., Fu, L., Walker, A., Chen, X., Lovejoy, D. B., Hao, M., Lee, A., Chung, R., Rizos, H., Irvine, M., Zheng, M., Liu, X., Lu, Y. & Shi, B., 13 May 2019, In : Biomacromolecules. 20, 5, p. 2148-2158 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Controlled drug delivery
Dendrimers
Cytotoxicity
Doxorubicin
Labels

Modulation of protein accumulation and uses therefor

Rayner, S., Lee, A., Chung, R. & Blair, I., 3 Oct 2019, IPC No. A61K 48/00, A61P 25/28, C12N 15/86, C07K 14/47, G01N 33/50, Patent No. US2019298860, Priority date 7 Nov 2017, Priority No. WO2017AU51225

Research output: PatentResearch

Open Access
Motor Neurons
Nerve Degeneration
Proteins
Cyclins
Nucleic Acids

Modulation of protein accumulation and uses therefor

Rayner, S., Lee, A., Chung, R. & Blair, I., 9 May 2019, IPC No. C12N 15/861 (2006.01), A61K 48/00 (2006.01), C12Q 1/68 (2018.01), Patent No. AU2017353361, 7 Nov 2017, Priority date 7 Nov 2017, Priority No. WO2017AU51225

Research output: PatentResearch

Open Access
Motor Neurons
Nerve Degeneration
Proteins
Cyclins
Nucleic Acids

Activities 2010 2019

Application of proteomics to characterise mechanisms of neurodegenerative diseases

Albert Lee (Speaker)
5 Jun 2019

Activity: Talk or presentationInvited talk

Biomedical Sciences Teaching and Learning seminars

Albert Lee (Participant)
2019 → …

Activity: Participating in or organising an eventOrganising a conference, workshop, ...

Cell Biology and Toxicology (Journal)

Albert Lee (Reviewer)
2019 → …

Activity: Publication peer-review and editorial workPublication Peer-review

NHMRC Ideas grant and panel assessor

Albert Lee (Other)
2019 → …

Activity: Other

Springer, Springer Nature (Publisher)

Albert Lee (Reviewer)
2019 → …

Activity: Publication peer-review and editorial workPublication Peer-review