• 971 Citations
  • 12 h-Index
20062022

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Article
2020

Central metal-derived co-assembly of biomimetic GdTPP/ZnTPP porphyrin nanocomposites for enhanced dual-modal imaging-guided photodynamic therapy

Wang, J., Wang, Z., Zhong, Y., Zou, Y., Wang, C., Wu, H., Lee, A., Yang, W., Wang, X., Liu, Y., Zhang, D., Yan, J., Hao, M., Zheng, M., Chung, R., Bai, F. & Shi, B., Jan 2020, In : Biomaterials. 229, p. 1-13 13 p., 119576.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Charge conversional biomimetic nanocomplexes as a multifunctional platform for boosting orthotopic glioblastoma RNAi therapy

Liu, Y., Zou, Y., Feng, C., Lee, A., Yin, J., Chung, R., Park, J. B., Rizos, H., Tao, W., Zheng, M., Farokhzad, O. C. & Shi, B., 11 Mar 2020, In : Nano Letters. 20, 3, p. 1637-1646 10 p.

Research output: Contribution to journalArticle

SERS-based nanostrategy for rapid anemia diagnosis

Muhammad, P., Hanif, S., Yan, J., Rehman, F. U., Wang, J., Khan, M., Chung, R., Lee, A., Zheng, M., Wang, Y. & Shi, B., 21 Jan 2020, In : Nanoscale. 12, 3, p. 1948-1957 10 p.

Research output: Contribution to journalArticle

2019

Bioreducible zinc(II)–dipicolylamine functionalized hyaluronic acid mediates safe siRNA delivery and effective glioblastoma RNAi therapy

Zheng, M., Yang, Z., Chen, S., Wu, H., Liu, Y., Wright, A., Lu, J-W., Xia, X., Lee, A., Zhang, J., Yin, H., Wang, Y., Ruan, W. & Liang, X-J., 22 Jan 2019, In : ACS Applied Bio Materials. 2, 1, p. 362-369 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery

Wang, G., Fu, L., Walker, A., Chen, X., Lovejoy, D. B., Hao, M., Lee, A., Chung, R., Rizos, H., Irvine, M., Zheng, M., Liu, X., Lu, Y. & Shi, B., 13 May 2019, In : Biomacromolecules. 20, 5, p. 2148-2158 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis

Wright, A. L., Le, S., Mehta, P., Gatta, P. D., Berning, B. A., Jacobs, K. R., Gul, H., Gil, R. S., Hedl, T. J., Riddell, W. R., Watson, O., Keating, S. S., Chung, R. S., Atkin, J. D., Lee, A., Shi, B., Blizzard, C. A., Morsch, M. & Walker, A. K., 29 Aug 2019, (In preparation) In : bioRxiv.

Research output: Contribution to journalArticle

2018

Aurora kinase B regulates axonal outgrowth and regeneration in the spinal motor neurons of developing zebrafish

Gwee, S. S. L., Radford, R. A. W., Chow, S., Syal, M. D., Morsch, M., Formella, I., Lee, A., Don, E. K., Badrock, A. P., Cole, N. J., West, A. K., Cheung, S. N. S. & Chung, R. S., Dec 2018, In : Cellular and Molecular Life Sciences. 75, 23, p. 4269-4285 17 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

DNA nanoclew templated spherical nucleic acids for siRNA delivery

Ruan, W., Zheng, M., An, Y., Liu, Y., Lovejoy, D., Hao, M., Zou, Y., Lee, A., Yang, S., Lu, Y., Morsch, M., Chung, R. & Shi, B., 14 Apr 2018, In : Chemical Engineering Communications. 54, p. 3609-3612 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D. & 2 others, Molloy, M. P. & Chung, R. S., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

Formella, I., Svahn, A. J., Radford, R. A. W., Don, E. K., Cole, N. J., Hogan, A., Lee, A., Chung, R. S. & Morsch, M., 1 Oct 2018, In : Redox Biology. 19, p. 226-234 9 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
90 Downloads (Pure)
2017

A Versatile upconversion surface evaluation platform for bio-nano surface selection for the nervous system

Fu, L., Morsch, M., Shi, B., Wang, G., Lee, A., Radford, R., Lu, Y., Jin, D. & Chung, R., 17 Aug 2017, In : Nanoscale. 9, 36, p. 13683-13692 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex

Lee, A., Rayner, S. L., De Luca, A., Gwee, S. S. L., Morsch, M., Sundaramoorthy, V., Shahheydari, H., Ragagnin, A., Shi, B., Yang, S., Williams, K. L., Don, E. K., Walker, A. K., Zhang, K. Y., Yerbury, J. J., Cole, N. J., Atkin, J. D., Blair, I. P., Molloy, M. P. & Chung, R. S., 2017, In : Open Biology. 7, 10, p. 1-11 11 p., 170058.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
13 Downloads (Pure)
5 Citations (Scopus)

Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype

Hogan, A. L., Don, E. K., Rayner, S. L., Lee, A., Laird, A. S., Watchon, M., Winnick, C., Tarr, I. S., Morsch, M., Fifita, J. A., Gwee, S. S. L., Formella, I., Hortle, E., Yuan, K. C., Molloy, M. P., Williams, K. L., Nicholson, G. A., Chung, R. S., Blair, I. P. & Cole, N. J., 15 Jul 2017, In : Human molecular genetics. 26, 14, p. 2616-2626 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Multifunctional hybrid nanoparticles for traceable drug delivery and intracellular microenvironment-controlled multistage drug-release in neurons

Shi, B., Du, X., Chen, J., Fu, L., Morsch, M., Lee, A., Liu, Y., Cole, N. & Chung, R., 24 May 2017, In : Small. 13, 20, p. 1-10 10 p., 1603966.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Plasma biomarker proteins for detection of human growth hormone administration in athletes

Tan, S-H., Lee, A., Pascovici, D., Care, N., Birzniece, V., Ho, K., Molloy, M. P. & Khan, A., 30 Aug 2017, In : Scientific Reports. 7, 1, p. 1-12 12 p., 10039.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
12 Downloads (Pure)

Triggering cell stress and death using conventional UV laser confocal microscopy

Morsch, M., Radford, R. A. W., Don, E. K., Lee, A., Hortle, E., Cole, N. J. & Chung, R. S., 2 Mar 2017, In : Journal of visualized experiments : JoVE. 2017, 120, p. 1-9 9 p., e54983.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Williams, K. L., Topp, S., Yang, S., Smith, B., Fifita, J. A., Warraich, S. T., Zhang, K. Y., Farrawell, N., Vance, C., Hu, X., Chesi, A., Leblond, C. S., Lee, A., Rayner, S. L., Sundaramoorthy, V., Dobson-Stone, C., Molloy, M. P., Van Blitterswijk, M., Dickson, D. W., Petersen, R. C. & 48 others, Graff-Radford, N. R., Boeve, B. F., Murray, M. E., Pottier, C., Don, E., Winnick, C., McCann, E. P., Hogan, A., Daoud, H., Levert, A., Dion, P. A., Mitsui, J., Ishiura, H., Takahashi, Y., Goto, J., Kost, J., Gellera, C., Gkazi, A. S., Miller, J., Stockton, J., Brooks, W. S., Boundy, K., Polak, M., Muñoz-Blanco, J. L., Esteban-Pérez, J., Rábano, A., Hardiman, O., Morrison, K. E., Ticozzi, N., Silani, V., De Belleroche, J., Glass, J. D., Kwok, J. B. J., Guillemin, G. J., Chung, R. S., Tsuji, S., Brown, R. H., García-Redondo, A., Rademakers, R., Landers, J. E., Gitler, A. D., Rouleau, G. A., Cole, N. J., Yerbury, J. J., Atkin, J. D., Shaw, C. E., Nicholson, G. A. & Blair, I. P., 15 Apr 2016, In : Nature Communications. 7, p. 1-8 8 p., 11253.

Research output: Contribution to journalArticle

Open Access
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78 Citations (Scopus)
15 Downloads (Pure)

Combined Antibody/Lectin enrichment identifies extensive changes in the O-GIcNAc Sub-proteome upon Oxidative stress

Lee, A., Miller, D., Henry, R., Paruchuri, V. D. P., O'Meally, R. N., Boronina, T., Cole, R. N. & Zachara, N. E., 2 Dec 2016, In : Journal of Proteome Research. 15, 12, p. 4318-4336 19 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2015

In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord

Morsch, M., Radford, R., Lee, A., Don, E. K., Badrock, A. P., Hall, T. E., Cole, N. J. & Chung, R., 31 Aug 2015, In : Frontiers in Cellular Neuroscience. 9, p. 1-11 11 p., 321.

Research output: Contribution to journalArticle

Open Access
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38 Citations (Scopus)
14 Downloads (Pure)

Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway

Zhong, J., Martinez, M., Sengupta, S., Lee, A., Wu, X., Chaerkady, R., Chatterjee, A., O'Meally, R. N., Cole, R. N., Pandey, A. & Zachara, N. E., 1 Jan 2015, In : Proteomics. 15, 2-3, p. 591-607 17 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2014

Characterization of the specificity of O-GlcNAc reactive antibodies under conditions of starvation and stress

Reeves, R. A., Lee, A., Henry, R. & Zachara, N. E., 15 Jul 2014, In : Analytical Biochemistry. 457, p. 8-18 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2013
6 Citations (Scopus)
2011

Liver membrane proteome glycosylation changes in mice bearing an extra-hepatic tumor

Lee, A., Chick, J. M., Kolarich, D., Haynes, P. A., Robertson, G. R., Tsoli, M., Jankova, L., Clarke, S. J., Packer, N. H. & Baker, M. S., Sep 2011, In : Molecular and Cellular Proteomics. 10, 9, p. 1-18 18 p., M900538-MCP200.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Quantitative N-linked glycoproteomics of myocardial ischemia and reperfusion injury reveals early remodeling in the extracellular environment

Parker, B. L., Palmisano, G., Edwards, A. V. G., White, M. Y., Engholm-Keller, K., Lee, A., Scott, N. E., Kolarich, D., Hambly, B. D., Packer, N. H., Larsen, M. R. & Cordwell, S. J., Aug 2011, In : Molecular and Cellular Proteomics. 10, 8, p. 1-13 13 p., M110.006833.

Research output: Contribution to journalArticle

73 Citations (Scopus)
2010

The lectin riddle: Glycoproteins fractionated from complex mixtures have similar glycomic profiles

Lee, A., Nakano, M., Hincapie, M., Kolarich, D., Baker, M. S., Hancock, W. S. & Packer, N. H., 1 Aug 2010, In : OMICS A Journal of Integrative Biology. 14, 4, p. 487-499 13 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2009

Rat liver membrane glycoproteome: Enrichment by phase partitioning and glycoprotein capture

Lee, A., Kolarich, D., Haynes, P. A., Jensen, P. H., Baker, M. S. & Packer, N. H., Feb 2009, In : Journal of Proteome Research. 8, 2, p. 770-781 12 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)