Alison Rodger

Professor

  • 6256 Citations
  • 43 h-Index
1983 …2018
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Personal profile

Biography

Alison Rodger moved to Macquarie in 2017 after over 20 years at the University of Warwick. Her research focuses on understanding the structure and function of biomacromolecules and their assemblies. Her particular expertise is with spectroscopic biophysical methods particularly circular dichroism and linear dichroism in the UV, visible and infra red regions of the spectrum for use with nucleic acids, proteins, lipids, and carbohydrates. She designs and applies new techniques to understand how biomolecules interact. She is currently working to understanding molecular aspects of bacterial cell-division and to develop and apply Raman Linear Difference Spectroscopy which she invented and various forms of infra-red spectroscopy. At Macquarie she is establishing an open access biophysical spectroscopy laboratory for collaborators and commercial users.

Alison received her BSc, PhD and DSc from Sydney University, her MA from Oxford, a DSc from Warwick, and her BA from Chester. She was a Beatrice Dale Fellow at Newnham College Cambridge for three years from 1985 while also an Overseas Scholar of the Royal Commission for the Exhibition of 1851. Alison then spent six years in Oxford as Unilever Fellow at St Catherine's College and Violette and Samuel Glasstone Fellow at St Hilda’s. At that time she set up the first Couette flow linear dichroism facilities in the UK and began her programme of analytical science method development for biomacromolecules.

At the University of Warwick Alison was the founding director of the Molecular Organisation and Assembly in Cells Doctoral Training Centre funded by the Engineering and Physical Sciences Research Council and also the head of the Department of Chemistry. She is passionate about supporting early career researchers, especially those working across disciplines and is a member of the Plotina EU network which is funded by Horizon 2020 to facilitate the development of Gender Equality Plans in Research Performing Organisations. Alison enjoyed every minute of her 4 years on the Royal Society of Chemistry Council which finished in July 2017.

 

Research interests

Solution phase biomacromolecule structure and function

  1. Development of spectroscopic techniques, particularly linear and circular dichroisms and Raman methods, for the study of biomacromolecules.
  2. Structure, function and intermolecular interactions of protein systems, including fibrous and membrane proteins.
  3. Structure and function of DNA, DNA/ligand and DNA/protein systems.
  4. Biophysics of bacterial cell division.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Dichroism Engineering & Materials Science
Circular Dichroism Medicine & Life Sciences
DNA Medicine & Life Sciences
Spectrum Analysis Medicine & Life Sciences
Ligands Medicine & Life Sciences
Coordination Complexes Medicine & Life Sciences
Peptides Medicine & Life Sciences
Ruthenium Medicine & Life Sciences

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Projects 2018 2018

Research Output 1983 2018

Fluorescence detected linear dichroism spectroscopy: a selective and sensitive probe for fluorophores in flow-oriented systems

Wemyss, A. M., Chmel, N. P., Lobo, D. P., Sutherland, J. A., Dafforn, T. R. & Rodger, A. 1 Mar 2018 In : Chirality. 30, 3, p. 227-237 11 p.

Research output: Contribution to journalArticle

Fluorophores
Dichroism
Spectrum Analysis
Fluorescence
Spectroscopy

Beyond the discovery void: New targets for antibacterial compounds

Broughton, C. E., Van Den Berg, H. A., Wemyss, A. M., Roper, D. I. & Rodger, A. 1 Jun 2016 In : Science Progress. 99, 2, p. 153-182 30 p.

Research output: Contribution to journalArticle

Anti-Bacterial Agents

Biophysical characterization of a protein for structure comparison: Methods for identifying insulin structural changes

Sklepari, M., Rodger, A., Reason, A., Jamshidi, S., Prokes, I. & Blindauer, C. A. 7 Nov 2016 In : Analytical Methods. 8, 41, p. 7460-7471 12 p.

Research output: Contribution to journalArticle

Insulin
Dichroism
Biosimilar Pharmaceuticals
Molecular structure
Proteins

Linear dichroism as a probe of molecular structure and interactions

Rodger, A., Dorrington, G. & Ang, D. L. 21 Dec 2016 In : Analyst. 141, 24, p. 6490-6498 9 p.

Research output: Contribution to journalReview article

Molecular interactions
Dichroism
Molecular Structure
Molecular structure
probe

Multifaceted Studies of the DNA Interactions and In Vitro Cytotoxicity of Anticancer Polyaromatic Platinum(II) Complexes

Pages, B. J., Sakoff, J., Gilbert, J., Rodger, A., Chmel, N. P., Jones, N. C., Kelly, S. M., Ang, D. L. & Aldrich-Wright, J. R. 2016 In : Chemistry - A European Journal. 22, 26, p. 8943-8954 12 p.

Research output: Contribution to journalArticle

Cytotoxicity
Platinum
DNA
2,2'-Dipyridyl
Enantiomers