Projects per year
Personal profile
Biography
Amy K. Cain is an ARC Future Fellow and Associate Professor of Molecular Biology in the School of Natural Sciences and the ARC Centre of Excellence in Synthetic Biology at Macquarie University, Sydney. She has worked in academic groups, hospital labs and in the pharmaceutical industry across Australia, Cambridge and Oxford in the UK, Malawi (sub-Saharan Africa), and Boston (USA). Her current research focuses on developing new-to-nature antibiotics and uncovering bacterial stress response systems in hospital pathogens using functional genomic techniques. She is the founder and Director of the Galleria Research Facility, an ethical and cost-effective in vivo model for testing pathogenicity of microbes, and toxicity and efficacy of new drugs.
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Collaborations and top research areas from the last five years
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Advancing Nanomaterials for Improved Wound Dressings in Chronic Wound Care
Asadnia, M. (Primary Chief Investigator), Cain, A. (Chief Investigator) & Pastras, C. (Chief Investigator)
16/12/24 → 15/12/27
Project: Research
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Head Agreement (Griffith led): Solving Plastic Waste CRC
Chen, C. (Chief Investigator), Gu, T. (Primary Chief Investigator), Singh, A. (Chief Investigator), Sheng, M. (Chief Investigator), Yang, J. (Chief Investigator), Beheshti, A. (Chief Investigator), Wang, Y. (Chief Investigator), Asadnia, M. (Chief Investigator), Bishop, M. (Chief Investigator), Cain, A. (Chief Investigator), Feih, S. (Chief Investigator), Naebe, M. (Chief Investigator), Giurco, D. (Chief Investigator) & Ball, A. (Chief Investigator)
15/09/24 → 15/09/34
Project: Research
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FT22: Microbial junk food: developing synthetic platforms for plastic degradation
Cain, A. (Primary Chief Investigator)
2/01/23 → 1/01/27
Project: Research
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FAAB: ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB)
Rodger, A. (Primary Chief Investigator), Sunna, A. (Chief Investigator), Garcia-Bennett, A. (Chief Investigator), Guillemin, G. (Chief Investigator), Packer, N. (Chief Investigator), Thaysen-Andersen, M. (Chief Investigator), Cain, A. (Chief Investigator), Connor, M. (Chief Investigator), Haynes, P. (Chief Investigator), Paulsen, I. (Chief Investigator), Ponton, F. (Chief Investigator), Tetu, S. (Chief Investigator), Wang, Y. (Chief Investigator), Adcock, J. (Chief Investigator), Callahan, D. (Chief Investigator), Walsh, T. R. (Chief Investigator), Joyce, P. (Chief Investigator), Prestidge, C. A. (Chief Investigator), Reddy, N. (Chief Investigator), Ashton, J. (Partner Investigator), Ball, M. (Partner Investigator), Bucca, D. (Partner Investigator), de Silva, T. (Partner Investigator), Ferguson, K. (Partner Investigator), Gilbert, A. (Partner Investigator), Gilbert, E. (Partner Investigator), Hayes, E. (Partner Investigator), Mazumder, D. (Partner Investigator), Morrison, J. (Partner Investigator), Petrie, J. (Partner Investigator), Pollard, N. (Partner Investigator), Ruff, N. (Partner Investigator), Stockham, K. (Partner Investigator), Winberg, P. (Partner Investigator) & De Simone, A. (Partner Investigator)
21/02/22 → 20/02/27
Project: Research
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Circuit Breaker: Investigating the regulatory circuits controlling expression of drug efflux pumps in the nosocomial pathogen Acinetobacter baumannii
Paulsen, I. (Primary Chief Investigator), Hassan, K. (Chief Investigator), Cain, A. (NHMRC - Associate Investigator) & Elbourne, L. (NHMRC - Associate Investigator)
1/01/17 → …
Project: Research
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Characterising the multiple-plastic degrading strain of Bacillus subtilis GM_03 From the Galleria mellonella microbiome
Facey, F. S. B., Maharjan, R., Dinh, H., Buchanan, J. S., Connal, L. A., Tay, A. P., Paulsen, I. T. & Cain, A. K., Oct 2025, In: Environmental Microbiology Reports. 17, 5, p. 1-11 11 p., e70216.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Photo-excited fibrous membranes for enhanced water disinfection
Xiao, H., Lott, H., Nagy, S., Baji, A., Asadnia, M., Cain, A. K., Abbassi, R. & Mainali, B., Aug 2025, In: Journal of Water Process Engineering. 76, p. 1-10 10 p., 108086.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Synthesis of a new purine analogue class with antifungal activity and improved potency against fungal IP3-4K
Desmarini, D., Truong, D., Sethiya, P., Liu, G., Bowring, B., Jessen, H., Dinh, H., Cain, A. K., Thompson, P. E. & Djordjevic, J. T., 11 Apr 2025, In: ACS Infectious Diseases. 11, 4, p. 940-953 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)19 Downloads (Pure) -
Transposon insertion sequencing reveals novel hypermutator genes in Acinetobacter baumannii
Short, F. L., Maharjan, R., Li, L., Afrin, N., Delgado, N., Boinett, C. J., Parkhill, J., Cain, A. K. & Paulsen, I. T., Aug 2025, In: mBio. 16, 8, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Uncovering the antifungal potential of Cannabidiol and Cannabidivarin
Dinh, H., Fernandes, K. E., Erpf, P. E., Clay, E. J. M., Tay, A. P., Nagy, S. S., Schaefer, S., Maharjan, R., Lenardon, M. D., Multari, D. H., Haynes, P. A., Paulsen, I. T., Santiago, M. J., Connor, M., Carter, D. & Cain, A. K., 2025, In: PLoS Neglected Tropical Diseases. 19, 6, p. 1-24 24 p., e0013081.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Downloads (Pure)
Prizes
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Faculty Excellence Award 2020 - Inter-Departmental Collaboration
Cain, A. (Recipient), Fernandez, M. (Recipient), Lustri, C. (Recipient) & Swain, M. (Recipient), 3 Dec 2020
Prize: Other distinction
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Fellowship of the Australian Society for Microbiology.
Cain, A. (Recipient), 5 May 2021
Prize: Honorary award
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Impacts
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JAMSpod (microbiology podcast)
Cain, A. (Participant), Semenec, L. (Participant) & Goold, H. (Participant)
Impact: Society impacts