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Personal profile

Biography

Ananda is a PhD candidate under a cotutelle program involving Macquarie University and Universidade Federal de Santa Catarina, Brazil. She has been working in the fields of Neurosciences, Neuroimmunology, Tryptophan and Tetrahydrobiopterin (BH4) metabolisms. In addition to her PhD research, Ananda works as a research assistant performing targeted metabolomics analyses including High-Performance Liquid Chromatography (HPLC), Gas Chromatography/Mass Spectrometry (GC/MS) and Liquid Chromatography/Mass Spectrometry (LC/MS).

Research interests

Her research interests focus particularly on the involvement of the tryptophan catabolism (via the kynurenine pathway) and BH4 metabolism in human inflammatory diseases and the identification of biomarkers to monitor the efficacy of novel therapeutic strategies to treat inflammatory chronic conditions.

She is currently working on the understanding of the the link between pain sensitization and two metabolic pathways, the synthesis of BH4 and the kynurenine pathway. Specifically, her project focuses on of the effect of xanthurenic acid (a kynurenine pathway intermediate) on the levels of the nociceptive compound BH4, and how that impacts on the redox and inflammatory status of the tissue that may facilitate pain induction.

Education/Academic qualification

Master of Neurosciences

1 May 201516 May 2017

Physiotherapist

1 Mar 20109 Dec 2014

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Research Outputs

Kynurenine, tetrahydrobiopterin, and cytokine inflammatory biomarkers in individuals affected by diabetic neuropathic pain

Staats Pires, A., Heng, B., Tan, V. X., Latini, A., Russo, M. A., Santarelli, D. M., Bailey, D., Wynne, K., O’Brien, J. A., Guillemin, G. J. & Austin, P. J., 21 Aug 2020, In : Frontiers in Neuroscience. 14, p. 1-12 12 p., 890.

Research output: Contribution to journalArticle

Open Access
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  • Kynurenine and tetrahydrobiopterin pathways crosstalk in pain hypersensitivity

    Staats Pires, A., Tan, V. X., Heng, B., Guillemin, G. J. & Latini, A., 24 Jun 2020, In : Frontiers in Neuroscience. 14, p. 1-12 12 p., 620.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)

    Novel immune biomarkers in complex regional pain syndrome

    Russo, M. A., Georgius, P., Staats Pires, A., Heng, B., Allwright, M., Guennewig, B., Santarelli, D. M., Bailey, D., Fiore, N. T., Tan, V. X., Latini, A., Guillemin, G. J. & Austin, P. J., 16 Jul 2020, (Accepted/In press) In : Journal of Neuroimmunology. 347, p. 1-11 11 p., 577330.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Tetrahydrobiopterin improves hippocampal nitric oxide-linked long-term memory

    Latini, A., de Bortoli da Silva, L., da Luz Scheffer, D., Pires, A. C. S., de Matos, F. J., Nesi, R. T., Ghisoni, K., de Paula Martins, R., de Oliveira, P. A., Prediger, R. D., Ghersi, M., Gabach, L., Pérez, M. F., Rubiales-Barioglio, S., Raisman-Vozari, R., Mongeau, R., Lanfumey, L. & Aguiar, A. S., 1 Sep 2018, In : Molecular Genetics and Metabolism. 125, 1-2, p. 104-111 8 p.

    Research output: Contribution to journalArticle

  • 4 Citations (Scopus)

    Treating depression with exercise: the inflammasome inhibition perspective

    de Paula Martins, R., Lim, C. K., Ghisoni, K., Staats, A., Dallagnol, K., Solano, A., Guillemin, G. J., Aguiar Jr, A. S. & Latini, A., 17 Dec 2016, In : Journal of Systems and Integrative Neuroscience. 3, 1, p. 1-8 8 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 1 Downloads (Pure)

    Prizes

    Best poster presentation

    Ananda Staats Pires (Recipient), 24 May 2018

    Prize