Andreia Vaqueirinho de Pinho

Dr

  • 3232 Citations
  • 14 h-Index
20112020
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Personal profile

Biography

I developed my PhD research project in the lab led by Prof. Francisco Real at the Spanish National Cancer Research Centre in Madrid, where I studied the role of the tumour suppressor p53 in pancreatic cell differentiation, senescence and stemness.

After obtaining my PhD in 2011, I moved to Australia to join the group led by Prof. Ilse Rooman and Prof. Andrew Biankin at the Garvan Institute, where my research has focused on uncovering the function of novel candidate genes, found through genomic studies, in the development and progression of pancreatic cancer. I was a Cancer Institute NSW Early Career Fellow (2013-2017) and have been attributed several awards and honours, including the 2012 Young Garvan Award.

In 2018, I  joined Prof. Helen Rizos team at the Faculty of Medicine and Health Sciences, Macquarie University. Here, my research will focus on examining the response and resistance of melanoma and other types of cancer to immune and targeted therapies.

Education/Academic qualification

Biomedicine, PhD, Universitat Pompeu Fabra

20062011

Biology, BSc, MSc, Faculty of Sciences, University of Lisbon (FCUL)

20012005

External positions

Fingerprint Dive into the research topics where Andreia Vaqueirinho de Pinho is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Pancreatic Neoplasms Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences
Sirtuin 1 Medicine & Life Sciences
Acinar Cells Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Chronic Pancreatitis Medicine & Life Sciences
Pancreas Medicine & Life Sciences
Genome Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2019 2020

Research Outputs 2011 2019

  • 3232 Citations
  • 14 h-Index
  • 18 Article
  • 3 Review article
  • 1 Meeting abstract

ROBO2 is a stroma suppressor gene in the pancreas through regulation of TGF-β

Vaqueirinho de Pinho, A., Van Bulck, M., Chantrill, L. A., Arshi, M., Herrmann, D., Vennin, C., Australian Pancreatic Cancer Genome Initiative, Gill, A., Timpson, P., Biankin, A., Wu, J. & Rooman, I., 2019, In : Cancer immunology research. Volume 7, Issue 2 Supplement, 1 p., Abstract A100.

Research output: Contribution to journalMeeting abstractResearch

Suppressor Genes
Transforming Growth Factor beta
Pancreas
Adenocarcinoma
Myofibroblasts

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

Pinho, A. V., Van Bulck, M., Chantrill, L., Arshi, M., Sklyarova, T., Herrmann, D., Vennin, C., Gallego-Ortega, D., Mawson, A., Giry-Laterriere, M., Magenau, A., Leuckx, G., Baeyens, L., Gill, A. J., Phillips, P., Timpson, P., Biankin, A. V., Wu, J. & Rooman, I., 1 Dec 2018, In : Nature Communications. 9, 1, p. 1-14 14 p., 5083.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Suppressor Genes
suppressors
pancreas
Transforming Growth Factor beta
genes

Hypermutation in pancreatic cancer

Humphris, J. L., Patch, A. M., Nones, K., Bailey, P. J., Johns, A. L., McKay, S., Chang, D. K., Miller, D. K., Pajic, M., Kassahn, K. S., Quinn, M. C. J., Bruxner, T. J. C., Christ, A. N., Harliwong, I., Idrisoglu, S., Manning, S., Nourse, C., Nourbakhsh, E., Stone, A., Wilson, P. J. & 66 othersAnderson, M., Fink, J. L., Holmes, O., Kazakoff, S., Leonard, C., Newell, F., Waddell, N., Wood, S., Mead, R. S., Xu, Q., Wu, J., Pinese, M., Cowley, M. J., Jones, M. D., Nagrial, A. M., Chin, V. T., Chantrill, L. A., Mawson, A., Chou, A., Scarlett, C. J., Pinho, A. V., Rooman, I., Giry-Laterriere, M., Samra, J. S., Kench, J. G., Merrett, N. D., Toon, C. W., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Jamieson, N. B., McKay, C. J., Carter, C. R., Dickson, E. J., Graham, J. S., Duthie, F., Oien, K., Hair, J., Morton, J. P., Sansom, O. J., Grützmann, R., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Rusev, B., Corbo, V., Salvia, R., Cataldo, I., Tortora, G., Tempero, M. A., Australian Pancreatic Cancer Genome Initiative, Hofmann, O., Eshleman, J. R., Pilarsky, C., Scarpa, A., Musgrove, E. A., Gill, A. J., Pearson, J. V., Grimmond, S. M., Waddell, N. & Biankin, A. V., Jan 2017, In : Gastroenterology. 152, 1, p. 68-74.e2 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pancreatic Neoplasms
DNA Repair
Mutation
Immunotherapy
Patient Selection

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

Balachandran, V. P., Luksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., Senbabaoglu, Y., Wells, D. K., Cary, C. I. O., Grbovic-Huezo, O., Attiyeh, M., Medina, B., Zhang, J., Loo, J., Saglimbeni, J., Abu-Akeel, M., Zappasodi, R. & 19 othersRiaz, N., Smoragiewicz, M., Kelley, Z. L., Basturk, O., Australian Pancreatic Cancer Genome Initiative, Goenen, M., Levine, A. J., Allen, P. J., Fearon, D. T., Merad, M., Gnjatic, S., Iacobuzio-Donahue, C. A., Wolchok, J. D., DeMatteo, R. P., Chan, T. A., Greenbaum, B. D., Merghoub, T., Leach, S. D. & Bassi, C., 23 Nov 2017, In : Nature. 551, 7681, p. 512-516 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Lost in translation: returning germline genetic results in genome-scale cancer research

Johns, A. L., McKay, S. H., Humphris, J. L., Pinese, M., Chantrill, L. A., Mead, R. S., Tucker, K., Andrews, L., Goodwin, A., Leonard, C., High, H. A., Nones, K., Patch, A. M., Merrett, N. D., Pavlakis, N., Kassahn, K. S., Samra, J. S., Miller, D. K., Chang, D. K., Pajic, M. & 7 othersAustralian Pancreatic Cancer Genome Initiative, Pearson, J. V., Grimmond, S. M., Waddell, N., Zeps, N., Gill, A. J. & Biankin, A. V., 28 Apr 2017, In : Genome Medicine. 9, 1, p. 1-9 9 p., 41.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Genome
Pancreatic Neoplasms
Research
Neoplasms
Genes