Andreia Vaqueirinho de Pinho

Dr

  • 4114 Citations
  • 15 h-Index
20112020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Outputs

  • 4114 Citations
  • 15 h-Index
  • 19 Article
  • 3 Review article
  • 1 Chapter
  • 1 Meeting abstract
Filter
Article
2020

HNF4A and GATA6 loss reveals therapeutically actionable subtypes in pancreatic cancer

Brunton, H., Caligiuri, G., Cunningham, R., Upstill-Goddard, R., Bailey, U-M., Garner, I. M., Nourse, C., Dreyer, S., Jones, M., Moran-Jones, K., Wright, D. W., Paulus-Hock, V., Nixon, C., Thomson, G., Jamieson, N. B., McGregor, G. A., Evers, L., McKay, C. J., Gulati, A., Brough, R. & 26 others, Bajrami, I., Pettitt, S. J., Dziubinski, M. L., Barry, S. T., Grützmann, R., Brown, R., Curry, E., Glasgow Precision Oncology Laboratory, Australian Pancreatic Cancer Genome Initiative, Pajic, M., Musgrove, E. A., Petersen, G. M., Shanks, E., Ashworth, A., Crawford, H. C., Simeone, D. M., Froeling, F. E. M., Lord, C. J., Mukhopadhyay, D., Pilarsky, C., Grimmond, S. E., Morton, J. P., Sansom, O. J., Chang, D. K., Bailey, P. J. & Biankin, A. V., 12 May 2020, In : Cell Reports. 31, 6, p. 1-17 28 p., 107625.

Research output: Contribution to journalArticle

Open Access
File
2018

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

Pinho, A. V., Van Bulck, M., Chantrill, L., Arshi, M., Sklyarova, T., Herrmann, D., Vennin, C., Gallego-Ortega, D., Mawson, A., Giry-Laterriere, M., Magenau, A., Leuckx, G., Baeyens, L., Gill, A. J., Phillips, P., Timpson, P., Biankin, A. V., Wu, J. & Rooman, I., 1 Dec 2018, In : Nature Communications. 9, 1, p. 1-14 14 p., 5083.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
13 Downloads (Pure)
2017

Hypermutation in pancreatic cancer

Humphris, J. L., Patch, A. M., Nones, K., Bailey, P. J., Johns, A. L., McKay, S., Chang, D. K., Miller, D. K., Pajic, M., Kassahn, K. S., Quinn, M. C. J., Bruxner, T. J. C., Christ, A. N., Harliwong, I., Idrisoglu, S., Manning, S., Nourse, C., Nourbakhsh, E., Stone, A., Wilson, P. J. & 66 others, Anderson, M., Fink, J. L., Holmes, O., Kazakoff, S., Leonard, C., Newell, F., Waddell, N., Wood, S., Mead, R. S., Xu, Q., Wu, J., Pinese, M., Cowley, M. J., Jones, M. D., Nagrial, A. M., Chin, V. T., Chantrill, L. A., Mawson, A., Chou, A., Scarlett, C. J., Pinho, A. V., Rooman, I., Giry-Laterriere, M., Samra, J. S., Kench, J. G., Merrett, N. D., Toon, C. W., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Jamieson, N. B., McKay, C. J., Carter, C. R., Dickson, E. J., Graham, J. S., Duthie, F., Oien, K., Hair, J., Morton, J. P., Sansom, O. J., Grützmann, R., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Rusev, B., Corbo, V., Salvia, R., Cataldo, I., Tortora, G., Tempero, M. A., Australian Pancreatic Cancer Genome Initiative, Hofmann, O., Eshleman, J. R., Pilarsky, C., Scarpa, A., Musgrove, E. A., Gill, A. J., Pearson, J. V., Grimmond, S. M., Waddell, N. & Biankin, A. V., Jan 2017, In : Gastroenterology. 152, 1, p. 68-74.e2 9 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

Balachandran, V. P., Luksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., Senbabaoglu, Y., Wells, D. K., Cary, C. I. O., Grbovic-Huezo, O., Attiyeh, M., Medina, B., Zhang, J., Loo, J., Saglimbeni, J., Abu-Akeel, M., Zappasodi, R. & 19 others, Riaz, N., Smoragiewicz, M., Kelley, Z. L., Basturk, O., Australian Pancreatic Cancer Genome Initiative, Goenen, M., Levine, A. J., Allen, P. J., Fearon, D. T., Merad, M., Gnjatic, S., Iacobuzio-Donahue, C. A., Wolchok, J. D., DeMatteo, R. P., Chan, T. A., Greenbaum, B. D., Merghoub, T., Leach, S. D. & Bassi, C., 23 Nov 2017, In : Nature. 551, 7681, p. 512-516 5 p.

Research output: Contribution to journalArticle

248 Citations (Scopus)

Lost in translation: returning germline genetic results in genome-scale cancer research

Johns, A. L., McKay, S. H., Humphris, J. L., Pinese, M., Chantrill, L. A., Mead, R. S., Tucker, K., Andrews, L., Goodwin, A., Leonard, C., High, H. A., Nones, K., Patch, A. M., Merrett, N. D., Pavlakis, N., Kassahn, K. S., Samra, J. S., Miller, D. K., Chang, D. K., Pajic, M. & 7 others, Australian Pancreatic Cancer Genome Initiative, Pearson, J. V., Grimmond, S. M., Waddell, N., Zeps, N., Gill, A. J. & Biankin, A. V., 28 Apr 2017, In : Genome Medicine. 9, 1, p. 1-9 9 p., 41.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)

ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth

Rath, N., Morton, J. P., Julian, L., Helbig, L., Kadir, S., McGhee, E. J., Anderson, K. I., Kalna, G., Mullin, M., Pinho, A. V., Rooman, I., Samuel, M. S. & Olson, M. F., 1 Feb 2017, In : EMBO Molecular Medicine. 9, 2, p. 198-218 21 p.

Research output: Contribution to journalArticle

Open Access
File
45 Citations (Scopus)
74 Downloads (Pure)

Whole-genome landscape of pancreatic neuroendocrine tumours

Scarpa, A., Chang, D. K., Nones, K., Corbo, V., Patch, A. M., Bailey, P., Lawlor, R. T., Johns, A. L., Miller, D. K., Mafficini, A., Rusev, B., Scardoni, M., Antonello, D., Barbi, S., Cingarlini, S., Vicentini, C., Sikora, K. O., McKay, S., Quinn, M. C. J., Bruxner, T. J. C. & 84 others, Christ, A. N., Harliwong, I., Idrisoglu, S., McLean, S., Nourse, C., Nourbakhsh, E., Wilson, P. J., Anderson, M. J., Fink, J. L., Newell, F., Waddell, N., Holmes, O., Kazakoff, S. H., Leonard, C., Wood, S., Xu, Q., Nagaraj, S. H., Amato, E., Dalai, I., Bersani, S., Cataldo, I., Dei Tos, A. P., Capelli, P., Davì, M. V., Landoni, L., Malpaga, A., Miotto, M., Whitehall, V. L. J., Leggett, B. A., Harris, J. L., Harris, J., Jones, M. D., Humphris, J., Chantrill, L. A., Chin, V., Nagrial, A. M., Pajic, M., Scarlett, C. J., Pinho, A., Rooman, I., Toon, C., Wu, J., Pinese, M., Cowley, M., Barbour, A., Mawson, A., Humphrey, E. S., Colvin, E. K., Chou, A., Lovell, J. A., Jamieson, N. B., Duthie, F., Gingras, M. C., Fisher, W. E., Dagg, R. A., Lau, L. M. S., Lee, M., Pickett, H. A., Reddel, R. R., Samra, J. S., Kench, J. G., Merrett, N. D., Epari, K., Nguyen, N. Q., Zeps, N., Falconi, M., Simbolo, M., Butturini, G., Van Buren, G., Partelli, S., Fassan, M., Australian Pancreatic Cancer Genome Initiative, Khanna, K. K., Gill, A. J., Wheeler, D. A., Gibbs, R. A., Musgrove, E. A., Bassi, C., Tortora, G., Pederzoli, P., Pearson, J. V., Waddell, N., Biankin, A. V. & Grimmond, S. M., 2 Mar 2017, In : Nature. 543, 7643, p. 65-71 7 p.

Research output: Contribution to journalArticle

237 Citations (Scopus)
2016

Ampullary cancers harbor ELF3 tumor suppressor gene mutations and exhibit frequent WNT dysregulation

Gingras, M. C., Covington, K. R., Chang, D. K., Donehower, L. A., Gill, A. J., Ittmann, M. M., Creighton, C. J., Johns, A. L., Shinbrot, E., Dewal, N., Fisher, W. E., Pilarsky, C., Grützmann, R., Overman, M. J., Jamieson, N. B., Van Buren, G., Drummond, J., Walker, K., Hampton, O. A., Xi, L. & 158 others, Muzny, D. M., Doddapaneni, H., Lee, S. L., Bellair, M., Hu, J., Han, Y., Dinh, H. H., Dahdouli, M., Samra, J. S., Bailey, P., Waddell, N., Pearson, J. V., Harliwong, I., Wang, H., Aust, D., Oien, K. A., Hruban, R. H., Hodges, S. E., McElhany, A., Saengboonmee, C., Duthie, F. R., Grimmond, S. M., Biankin, A. V., Wheeler, D. A., Gibbs, R. A., Jones, M. D., Mawson, A., Scarlett, C. J., Brancato, M. A. L., Rowe, S. J., Simpson, S. H., Smith Martyn, M., Thomas, M. T., Chantrill, L. A., Chin, V. T., Angela, C., Cowley, M. J., Humphris, J. L., Mead, S., Nagrial, A. M., Pajic, M., Pettit, J., Pinese, M., Rooman, I., Wu, J., Tao, J., DiPietro, R., Watson, C., Steinmann, A., Lee, H. C., Wong, R., Pinho, A. V., Giry-Laterriere, M., Daly, R. J., Musgrove, E. A., Sutherland, R. L., Kassahn, K. S., Miller, D. K., Wilson, P. J., Patch, A. M., Song, S., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S., Gongora, M., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, C., Nones, K., Fink, L. J., Christ, A., Bruxner, T., Cloonan, N., Newell, F., Quinn, M., Nagaraj, S., Kazakoff, S., Waddell, N., Krisnan, K., Queelly, Wood, D., Pavlakis, N., Guminski, A., Toon, C., Asghari, R., Merrett, N. D., Pavey, D., Das, A., Cosman, P. H., Ismail, K., O'Connnor, C., Lam, V. W., McLeod, D., Pleass, H. C., Richardson, A., James, V., Kench, J. G., Cooper, C. L., Joseph, D., Sandroussi, C., Crawford, M., Gallagher, J., Texler, M., Forest, C., Laycock, A., Epari, K. P., Ballal, M., Fletcher, D. R., Mukhedkar, S., Spry, N. A., DeBoer, B., Chai, M., Zeps, N., Beilin, M., Feeney, K., Nguyen, N. Q., Ruszkiewicz, A. R., Worthley, C., Tan, C. P., Debrencini, T., Chen, J., Brooke-Smith, M. E., Papangelis, V., Tang, H., Barbour, A. P., Clouston, A. D., Martin, P., O'Rourke, T. J., Chiang, A., Fawcett, J. W., Slater, K., Yeung, S., Hatzifotis, M., Hodgkinson, P., Christophi, C., Nikfarjam, M., Mountain, A., Eshleman, J. R., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Hodgin, M., Scarpa, A., Lawlor, R. T., Beghelli, S., Corbo, V., Scardoni, M., Bassi, C., Tempero, M. A., Glasgow, G. & Graham, J. S., 2 Feb 2016, In : Cell Reports. 14, 4, p. 907-919 13 p.

Research output: Contribution to journalArticle

Open Access
File
44 Citations (Scopus)
1 Downloads (Pure)

Genomic analyses identify molecular subtypes of pancreatic cancer

Bailey, P., Chang, D. K., Nones, K., Johns, A. L., Patch, A. M., Gingras, M. C., Miller, D. K., Christ, A. N., Bruxner, T. J. C., Quinn, M. C., Nourse, C., Murtaugh, L. C., Harliwong, I., Idrisoglu, S., Manning, S., Nourbakhsh, E., Wani, S., Fink, L., Holmes, O., Chin, V. & 83 others, Anderson, M. J., Kazakoff, S., Leonard, C., Newell, F., Waddell, N., Wood, S., Xu, Q., Wilson, P. J., Cloonan, N., Kassahn, K. S., Taylor, D., Quek, K., Robertson, A., Pantano, L., Mincarelli, L., Sanchez, L. N., Evers, L., Wu, J., Pinese, M., Cowley, M. J., Jones, M. D., Colvin, E. K., Nagrial, A. M., Humphrey, E. S., Chantrill, L. A., Mawson, A., Humphris, J., Chou, A., Pajic, M., Scarlett, C. J., Pinho, A. V., Giry-Laterriere, M., Rooman, I., Samra, J. S., Kench, J. G., Lovell, J. A., Merrett, N. D., Toon, C. W., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Moran-Jones, K., Jamieson, N. B., Graham, J. S., Duthie, F., Oien, K., Hair, J., Grützmann, R., Maitra, A., Iacobuzio-Donahue, C. A., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Corbo, V., Bassi, C., Rusev, B., Capelli, P., Salvia, R., Tortora, G., Mukhopadhyay, D., Petersen, G. M., Munzy, D. M., Fisher, W. E., Karim, S. A., Eshleman, J. R., Hruban, R. H., Pilarsky, C., Morton, J. P., Sansom, O. J., Scarpa, A., Musgrove, E. A., Bailey, U. M. H., Hofmann, O., Sutherland, R. L., Wheeler, D. A., Gill, A. J., Gibbs, R. A., Pearson, J. V., Waddell, N., Biankin, A. V., Grimmond, S. M. & Australian Pancreatic Cancer Genome Initiative, 3 Mar 2016, In : Nature. 531, 7592, p. 47-52 6 p.

Research output: Contribution to journalArticle

942 Citations (Scopus)

Sirtuin1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions

Pinho, A. V., Mawson, A., Gill, A., Arshi, M., Warmerdam, M., Giry-Laterriere, M., Eling, N., Lie, T., Kuster, E., Camargo, S., Biankin, A. V., Wu, J. & Rooman, I., 2016, In : Oncotarget. 7, 46, p. 74768-74778 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2015

Pancreas-specific Sirt1-deficiency in mice compromises beta-cell function without development of hyperglycemia

Pinho, A. V., Bensellam, M., Wauters, E., Rees, M., Giry-Laterriere, M., Mawson, A., Ly, L. Q., Biankin, A. V., Wu, J., Laybutt, D. R. & Rooman, I., 5 Jun 2015, In : PLoS ONE. 10, 6, p. 1-13 13 p., e0128012.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
2 Downloads (Pure)

SOX9 regulates ERBB signalling in pancreatic cancer development

Grimont, A., Pinho, A. V., Cowley, M. J., Augereau, C., Mawson, A., Giry-Laterrière, M., Van Den Steen, G., Waddell, N., Pajic, M., Sempoux, C., Wu, J., Grimmond, S. M., Biankin, A. V., Lemaigre, F. P., Rooman, I. & Jacquemin, P., 1 Nov 2015, In : Gut. 64, 11, p. 1790-1799 10 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Whole genomes redefine the mutational landscape of pancreatic cancer

Waddell, N., Pajic, M., Patch, A. M., Chang, D. K., Kassahn, K. S., Bailey, P., Johns, A. L., Miller, D., Nones, K., Quek, K., Quinn, M. C. J., Robertson, A. J., Fadlullah, M. Z. H., Bruxner, T. J. C., Christ, A. N., Harliwong, I., Idrisoglu, S., Manning, S., Nourse, C., Nourbakhsh, E. & 70 others, Wani, S., Wilson, P. J., Markham, E., Cloonan, N., Anderson, M. J., Fink, J. L., Holmes, O., Kazakoff, S. H., Leonard, C., Newell, F., Poudel, B., Song, S., Taylor, D., Waddell, N., Wood, S., Xu, Q., Wu, J., Pinese, M., Cowley, M. J., Lee, H. C., Jones, M. D., Nagrial, A. M., Humphris, J., Chantrill, L. A., Chin, V., Steinmann, A. M., Mawson, A., Humphrey, E. S., Colvin, E. K., Chou, A., Scarlett, C. J., Pinho, A. V., Giry-Laterriere, M., Rooman, I., Samra, J. S., Kench, J. G., Pettitt, J. A., Merrett, N. D., Toon, C., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Jamieson, N. B., Graham, J. S., Niclou, S. P., Bjerkvig, R., Grützmann, R., Aust, D., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Corbo, V., Bassi, C., Falconi, M., Zamboni, G., Tortora, G., Tempero, M. A., Australian Pancreatic Cancer Genome Initiative, Gill, A. J., Eshleman, J. R., Pilarsky, C., Scarpa, A., Musgrove, E. A., Pearson, J. V., Biankin, A. V. & Grimmond, S. M., 26 Feb 2015, In : Nature. 518, 7540, p. 495-501 7 p.

Research output: Contribution to journalArticle

1020 Citations (Scopus)
2013

Amino acid transporters expression in acinar cells is changed during acute pancreatitis

Rooman, I., Lutz, C., Pinho, A. V., Huggel, K., Reding, T., Lahoutte, T., Verrey, F., Graf, R. & Camargo, S. M. R., 1 Jan 2013, In : Pancreatology. 13, 5, p. 475-485 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Histomolecular phenotypes and outcome in adenocarcinoma of the ampulla of vater

Chang, D. K., Jamieson, N. B., Johns, A. L., Scarlett, C. J., Pajic, M., Chou, A., Pinese, M., Humphris, J. L., Jones, M. D., Toon, C., Nagrial, A. M., Chantrill, L. A., Chin, V. T., Pinho, A. V., Rooman, I., Cowley, M. J., Wu, J., Mead, R. S., Colvin, E. K., Samra, J. S. & 19 others, Corbo, V., Bassi, C., Falconi, M., Lawlor, R. T., Crippa, S., Sperandio, N., Bersani, S., Dickson, E. J., Mohamed, M. A. A., Oien, K. A., Foulis, A. K., Musgrove, E. A., Sutherland, R. L., Kench, J. G., Carter, C. R., Gill, A. J., Scarpa, A., McKay, C. J. & Biankin, A. V., 1 Apr 2013, In : Journal of Clinical Oncology. 31, 10, p. 1348-1356 9 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Sirtuin-1 regulates acinar-to-ductal metaplasia and supports cancer cell viability in pancreatic cancer

Wauters, E., Sanchez-Arevalo Lobo, V. J., Pinho, A. V., Mawson, A., Herranz, D., Wu, J., Cowley, M. J., Colvin, E. K., Njicop, E. N., Sutherland, R. L., Liu, T., Serrano, M., Bouwens, L., Real, F. X., Biankin, A. V. & Rooman, I., 1 Apr 2013, In : Cancer Research. 73, 7, p. 2357-2367 11 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2012

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Biankin, A. V., Waddell, N., Kassahn, K. S., Gingras, M. C., Muthuswamy, L. B., Johns, A. L., Miller, D. K., Wilson, P. J., Patch, A. M., Wu, J., Chang, D. K., Cowley, M. J., Gardiner, B. B., Song, S., Harliwong, I., Idrisoglu, S., Nourse, C., Nourbakhsh, E., Manning, S., Wani, S. & 107 others, Gongora, M., Pajic, M., Scarlett, C. J., Gill, A. J., Pinho, A. V., Rooman, I., Anderson, M., Holmes, O., Leonard, C., Taylor, D., Wood, S., Xu, Q., Nones, K., Fink, J. L., Christ, A., Bruxner, T., Cloonan, N., Kolle, G., Newell, F., Pinese, M., Mead, R. S., Humphris, J. L., Kaplan, W., Jones, M. D., Colvin, E. K., Nagrial, A. M., Humphrey, E. S., Chou, A., Chin, V. T., Chantrill, L. A., Mawson, A., Samra, J. S., Kench, J. G., Lovell, J. A., Daly, R. J., Merrett, N. D., Toon, C., Epari, K., Nguyen, N. Q., Barbour, A., Zeps, N., Australian Pancreatic Cancer Genome Initiative, Kakkar, N., Zhao, F., Wu, Y. Q., Wang, M., Muzny, D. M., Fisher, W. E., Brunicardi, F. C., Hodges, S. E., Reid, J. G., Drummond, J., Chang, K., Han, Y., Lewis, L. R., Dinh, H., Buhay, C. J., Beck, T., Timms, L., Sam, M., Begley, K., Brown, A., Pai, D., Panchal, A., Buchner, N., De Borja, R., Denroche, R. E., Yung, C. K., Serra, S., Onetto, N., Mukhopadhyay, D., Tsao, M. S., Shaw, P. A., Petersen, G. M., Gallinger, S., Hruban, R. H., Maitra, A., Iacobuzio-Donahue, C. A., Schulick, R. D., Wolfgang, C. L., Morgan, R. A., Lawlor, R. T., Capelli, P., Corbo, V., Scardoni, M., Tortora, G., Tempero, M. A., Mann, K. M., Jenkins, N. A., Perez-Mancera, P. A., Adams, D. J., Largaespada, D. A., Wessels, L. F. A., Rust, A. G., Stein, L. D., Tuveson, D. A., Copeland, N. G., Musgrove, E. A., Scarpa, A., Eshleman, J. R., Hudson, T. J., Sutherland, R. L., Wheeler, D. A., Pearson, J. V., McPherson, J. D., Gibbs, R. A. & Grimmond, S. M., 15 Nov 2012, In : Nature. 491, 7424, p. 399-405 7 p.

Research output: Contribution to journalArticle

1100 Citations (Scopus)
2011

Adult pancreatic acinar cells dedifferentiate to an embryonic progenitor phenotype with concomitant activation of a senescence programme that is present in chronic pancreatitis

Pinho, A. V., Rooman, I., Reichert, M., De Medts, N., Bouwens, L., Rustgi, A. K. & Real, F. X., 1 Jul 2011, In : Gut. 60, 7, p. 958-966 9 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

p53-dependent regulation of growth, epithelial-mesenchymal transition and stemness in normal pancreatic epithelial cells

Pinho, A. V., Rooman, I. & Real, F. X., 15 Apr 2011, In : Cell Cycle. 10, 8, p. 1312-1321 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)