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Research Outputs 2014 2019

2019

Bioproducts From Euglena gracilis: synthesis and applications

Gissibl, A., Sun, A., Care, A., Nevalainen, H. & Sunna, A., 15 May 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 16 p., 108.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Euglena gracilis
Dietary Proteins
Vitamins
Metabolism
Lipids

Developing protein-based nanoparticles as versatile delivery systems for cancer therapy and imaging

Sandra, F., Khaliq, N. U., Sunna, A. & Care, A., Sep 2019, In : Nanomaterials. 9, 9, p. 1-25 25 p., 1329.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Nanoparticles
Proteins
Imaging techniques
Medical nanotechnology

Development of screening strategies for the identification of paramylon-degrading enzymes

Gissibl, A., Care, A., Sun, Y., Hobba, G., Nevalainen, H. & Sunna, A., Jun 2019, In : Journal of Industrial Microbiology and Biotechnology. 46, 6, p. 769-781 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Screening
Enzymes
Euglena gracilis
Assays
Escherichia coli

Experimental and theoretical tools to elucidate the binding mechanisms of solid-binding peptides

Bansal, R., Care, A., Lord, M. S., Walsh, T. R. & Sunna, A., 25 Sep 2019, In : New Biotechnology. 52, p. 9-18 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Peptides
Nanobiotechnology
Biomolecules
Substrates

Functionalized upconversion nanoparticles for targeted labelling of bladder cancer cells

Polikarpov, D., Liang, L., Care, A., Sunna, A., Campbell, D., Walsh, B., Balalaeva, I., Zvyagin, A., Gillatt, D. & Guryev, E., 2019, In : Biomolecules. 9, 12, p. 1-11 11 p., 820.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Mixed-mode liquid chromatography for the rapid analysis of biocatalytic glucaric acid reaction pathways

Petroll, K., Care, A., Waterstraat, M., Bergquist, P. & Sunna, A., 20 Aug 2019, In : Analytica Chimica Acta. 1066, p. 136-145 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Glucaric Acid
Liquid chromatography
Liquid Chromatography
liquid chromatography
acid

Tools and strategies for constructing cell-free enzyme pathways

Petroll, K., Kopp, D., Care, A., Bergquist, P. L. & Sunna, A., Jan 2019, In : Biotechnology Advances. 37, 1, p. 91-108 18 p.

Research output: Contribution to journalReview articleResearchpeer-review

Enzymes
Biocatalysis
Artificial Cells
Biofuels
Coenzymes
2018

Bioengineering strategies for protein-based nanoparticles

Diaz, D., Care, A. & Sunna, A., 23 Jul 2018, In : Genes. 9, 7, p. 1-30 30 p., 370.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Bioengineering
Nanoparticles
Proteins
Biocatalysis
Synthetic Biology

Microwave pretreatment of paramylon enhances the enzymatic production of soluble β-1,3-glucans with immunostimulatory activity

Gissibl, A., Care, A., Parker, L. M., Iqbal, S., Hobba, G., Nevalainen, H. & Sunna, A., 15 Sep 2018, In : Carbohydrate Polymers. 196, p. 339-347 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Microwaves
Glucan 1,3-beta-Glucosidase
Hydrolysis
Polymerization
Enzymatic hydrolysis

"Turn-on" fluorescent aptasensor based on AIEgen labeling for the localization of IFN-γ in live cells

Ma, K., Zhang, F., Sayyadi, N., Chen, W., Anwer, A. G., Care, A., Xu, B., Tian, W., Goldys, E. M. & Liu, G., Feb 2018, In : ACS Sensors. 3, 2, p. 320–326 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Labeling
Agglomeration
Cytotoxicity
Biocompatibility
Cytokines

Versatile platform for nanoparticle surface bioengineering based on SiO2-binding peptide and proteinaceous Barnase∗Barstar interface

Shipunova, V. O., Zelepukin, I. V., Stremovskiy, O. A., Nikitin, M. P., Care, A., Sunna, A., Zvyagin, A. V. & Deyev, S. M., 23 May 2018, In : ACS Applied Materials and Interfaces. 10, 20, p. 17437-17447 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Peptides
Nanoparticles
Biomolecules
Molecules
Proteins
2017

An innovative approach to bioremediation of mercury contaminated soils from industrial mining operations

McCarthy, D., Edwards, G. C., Gustin, M. S., Care, A., Miller, M. B. & Sunna, A., Oct 2017, In : Chemosphere. 184, p. 694-699 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Environmental Biodegradation
Bioremediation
Mercury
bioremediation
Soil

Deep-penetrating photodynamic therapy with KillerRed mediated by upconversion nanoparticles

Liang, L., Lu, Y., Zhang, R., Care, A., Ortega, T. A., Deyev, S. M., Qian, Y. & Zvyagin, A. V., 2017, In : Acta Biomaterialia. 51, p. 461-470 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Photodynamic therapy
Photochemotherapy
Nanoparticles
Photosensitizing Agents
Photosensitizers

Graphene quantum dot based "switch-on" nanosensors for intracellular cytokine monitoring

Liu, G., Zhang, K., Ma, K., Care, A., Hutchinson, M. R. & Goldys, E. M., 21 Apr 2017, In : Nanoscale. 9, 15, p. 4934-4943 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanosensors
Graphite
Epitopes
Graphene
Semiconductor quantum dots

Luminescent biomolecular complex and use thereof

Care, A., Sayyadi, N., Connally, R., Try, A., Bergquist, P. L. & Sunna, A., 2 Feb 2017, IPC No. G01N 33/533 (2006.01), Patent No. WO/2017/015693, Priority date 27 Jul 2015, Priority No. 2015902978

Research output: PatentResearch

Luminescence
Carrier Proteins
Technology
Peptides
Antibodies

Peptides and peptide-based biomaterials and their biomedical applications

Sunna, A. (ed.), Care, A. (ed.) & Bergquist, P. L. (ed.), 2017, Cham: Springer, Springer Nature. 300 p. (Advances in experimental medicine and biology; vol. 1030)

Research output: Book/ReportEdited Book/AnthologyResearchpeer-review

Solid-binding peptides for immobilisation of thermostable enzymes to hydrolyse biomass polysaccharides

Care, A., Petroll, K., Gibson, E. S. Y., Bergquist, P. L. & Sunna, A., 2 Feb 2017, In : Biotechnology for Biofuels. 10, 1, p. 1-16 16 p., 29.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Polysaccharides
polysaccharide
Immobilization
peptide
Biomass

Solid-binding peptides in biomedicine

Care, A., Bergquist, P. L. & Sunna, A., 2017, Peptides and Peptide-based Biomaterials and their Biomedical Applications. Sunna, A., Care, A. & Bergquist, P. L. (eds.). Cham, Switzerland: Springer, Springer Nature, p. 21-36 16 p. (Advances in experimental medicine and biology; vol. 1030). (Advances in Experimental Medicine and Biology).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Nanostructures
Nanostructured materials
Peptides
Metals
Biocompatibility

Targeted upconversion photoluminescent nanoconjugates selectively label TCC cells expressing Glypican-1

Polikarpov, D., Sabaretnam, T., Liang, L., Care, A., Sunna, A., Campbell, D., Walsh, B., Guillemin, G., Zvyagin, A. & Gillatt, D., Mar 2017, In : BJU international. 119, Suppl. 2, p. 72-72 1 p.

Research output: Contribution to journalMeeting abstractResearchpeer-review

2016

A novel universal detection agent for time-gated luminescence bioimaging

Sayyadi, N., Care, A., Connally, R. E., Try, A. C., Bergquist, P. L. & Sunna, A., 10 Jun 2016, In : Scientific Reports. 6, p. 1-9 9 p., 27564.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Luminescence
Lanthanoid Series Elements
Lysine
Ligands
Antibody Affinity

Facile assembly of functional upconversion nanoparticles for targeted cancer imaging and photodynamic therapy

Liang, L., Care, A., Zhang, R., Lu, Y., Packer, N. H., Sunna, A., Qian, Y. & Zvyagin, A. V., 18 May 2016, In : ACS Applied Materials and Interfaces. 8, 19, p. 11945-11953 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Photodynamic therapy
Nanoparticles
Proteins
Imaging techniques
Silicon Dioxide

Solid-binding peptides: immobilisation strategies for extremophile biocatalysis in biotechnology

Sunna, A., Care, A. & Bergquist, PL., 2016, Biotechnology of Extremophiles: Advances and challenges. Rampelotto, P. H. (ed.). Cham, Switzerland: Springer, Springer Nature, p. 637-674 38 p. (Grand Challenges in Biology and Biotechnology; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Biotechnology
Immobilized Enzymes
Peptides
Biofuels
Enzymes
2015

Building a platform technology for the self-assembly of functional upconversion nanoparticles

Care, A., Sunna, A. & Packer, N., 2015. 1 p.

Research output: Contribution to conferenceAbstractResearch

Solid-binding peptides: Smart tools for nanobiotechnology

Care, A., Bergquist, P. L. & Sunna, A., 1 May 2015, In : Trends in Biotechnology. 33, 5, p. 259-268 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Nanobiotechnology
Peptides
Nanostructures
Metals
Semiconductors
2014

A Robust and versatile bioconjugation method for micro- and nano-particles using an inorganic-binding peptide

Care, A., Bergquist, P. & Sunna, A., 2014.

Research output: Contribution to conferencePosterResearch

Biofunctionalization of silica-coated magnetic particles mediated by a peptide

Care, A., Chi, F., Bergquist, P. L. & Sunna, A., 2014, In : Journal of Nanoparticle Research. 16, 8, p. 1-9 9 p., 2543.

Research output: Contribution to journalArticleResearchpeer-review

G Protein
Silica
Peptides
Silicon Dioxide
peptides

Effect of Trichoderma reesei proteinases on the affinity of an inorganic-binding peptide

Care, A., Nevalainen, H., Bergquist, P. L. & Sunna, A., 2014, In : Applied Biochemistry and Biotechnology. 173, 8, p. 2225-2240 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Zeolites
Trichoderma
Peptides
Peptide Hydrolases
Derivatives

Immobilisation of hyperthermophilic enzymes to mineral matrices

Care, A., Bergquist, P. & Sunna, A., 2014, p. 282. 1 p.

Research output: Contribution to conferencePosterResearch

Rapid and simple functionalisation of inorganic materials using a peptide linker

Care, A. S., Bergquist, P. L. & Sunna, A., 2014.

Research output: Contribution to conferenceAbstractResearch