Projects per year
Personal profile
Biography
Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.
Qualifications
BMedScs (Hons) Macq, PhD Macq, MRACI CChem
Employment
| 2021 - | Associate Professor, Macquarie University |
| 2018 - 2020 | Senior Lecturer, Macquarie University |
| 2014 - 2017 | ARC Future Fellow, Macquarie University |
| 2012 - 2014 | Senior Research Officer, IMB, The University of Queensland |
| 2007 - 2012 | Research Officer, IMB, The University of Queensland |
| 2005 - 2007 | Postdoctoral Research Fellow, Macquarie University |
Research Interests
- Natural products chemistry
- Discovery and development of next-generation antibiotics
- Natural product mode of action
- Biodiscovery and structure elucidation
- Chemical biology using natural product probes
Fingerprint
Dive into the research topics where Andrew Piggott is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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UWA led: CRISPR-based pathway activation for bioactive molecule discovery in fungi
Chooi, Y. H., Piggott, A. & Keller, N.
11/02/21 → 10/02/24
Project: Research
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Reverse Chemical Proteomics: Harnessing Yeast Display for Drug Discovery
Piggott, A., Karuso, P., Kwon, H. J. & MQRES (International), M. (.
1/01/18 → 31/12/22
Project: Research
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Overcoming antibiotic resistance: rapid discovery of new antibacterial drug targets using chemicalproteomics
Piggott, A., MQRES, M., MQRES (International), M. (. & Capon, R.
7/04/14 → …
Project: Research
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Rapid Isolation System
Karuso, P., Taylor, P., Piggott, A., Liu, F., Jamie, J., Park, S. J., Jamie, I., Keaveney, S., Venkatesan, K. & Wong, D.
1/01/20 → 31/12/20
Project: Other
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GRF: Galleria Research Facility: Bringing a Flexible, Accessible and Ethical Animal Model to Macquarie
Cain, A., Short, F., Maselko, M., Paulsen, I., Gillings, M., Parker, L., Wang, Y., Jaschke, P. & Piggott, A.
1/01/20 → 31/12/20
Project: Other
Research Outputs
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Characterisation and heterologous biosynthesis of burnettiene A, a new polyene-decalin polyketide from Aspergillus burnettii
Roux, I., Bowles, S., Kalaitzis, J. A., Vuong, D., Lacey, E., Chooi, Y-H. & Piggott, A. M., 21 Nov 2021, In: Organic and Biomolecular Chemistry. 19, 43, p. 9506-9513 8 p.Research output: Contribution to journal › Article › peer-review
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Chlorinated metabolites from Streptomyces sp. highlight the role of biosynthetic mosaics and superclusters in the evolution of chemical diversity
Morshed, M. T., Lacey, E., Vuong, D., Lacey, A. E., Lean, S. S., Moggach, S. A., Karuso, P., Chooi, Y. H., Booth, T. J. & Piggott, A. M., 21 Jul 2021, In: Organic and Biomolecular Chemistry. 19, 27, p. 6147-6159 13 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Evaluation of benzguinols as next-generation antibiotics for the treatment of multidrug-resistant bacterial infections
Nguyen, H. T., Morshed, M. T., Vuong, D., Crombie, A., Lacey, E., Garg, S., Pi, H., Woolford, L., Venter, H., Page, S. W., Piggott, A. M., Trott, D. J. & Ogunniyi, A. D., Jun 2021, In: Antibiotics. 10, 6, p. 1-17 17 p., 727.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
Genome mining of Aspergillus hancockii unearths cryptic polyketide hancockinone A featuring a prenylated 6/6/6/5 carbocyclic skeleton
Li, H., Shu, S., Kalaitzis, J. A., Shang, Z., Vuong, D., Crombie, A., Lacey, E., Piggott, A. M. & Chooi, Y-H., 19 Nov 2021, In: Organic Letters. 23, 22, p. 8789-8793 5 p.Research output: Contribution to journal › Article › peer-review
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Hancockiamides: phenylpropanoid piperazines from Aspergillus hancockii are biosynthesised by a versatile dual single-module NRPS pathway
Li, H., Lacey, A. E., Shu, S., Kalaitzis, J. A., Vuong, D., Crombie, A., Hu, J., Gilchrist, C. L. M., Lacey, E., Piggott, A. M. & Chooi, Y. H., 21 Jan 2021, In: Organic and Biomolecular Chemistry. 19, 3, p. 587-595 9 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus)
Prizes
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Faculty of Science and Engineering Award for Excellence in Innovative Research Partnership
Piggott, Andrew (Recipient), 6 Dec 2019
Prize