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Andrew Piggott

Dr

 https://orcid.org/0000-0002-5308-5314
  • 1252 Citations
  • 20 h-Index
20002020

Research output per year

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Personal profile

Biography

Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.

Qualifications

BMedScs (Hons) Macq, PhD Macq, MRACI CChem

Employment

2018 -Senior Lecturer, Macquarie University
2014 - 2017ARC Future Fellow, Macquarie University
2012 - 2014Senior Research Officer, IMB, The University of Queensland
2007 - 2012Research Officer, IMB, The University of Queensland
2005 - 2007Postdoctoral Research Fellow, Macquarie University

Research Interests

  • Discovery and development of next-generation antibiotics
  • Natural product mode of action
  • Biodiscovery and structure elucidation
  • Chemical biology using natural product probes

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Projects

GRF: Galleria Research Facility: Bringing a Flexible, Accessible and Ethical Animal Model to Macquarie

Cain, A., Short, F., Maselko, M., Paulsen, I., Gillings, M., Parker, L., Wang, Y., Jaschke, P. & Piggott, A.

1/01/20 → 31/12/20

Project: Other

Reverse Chemical Proteomics: Harnessing Yeast Display for Drug Discovery

Piggott, A., Karuso, P., Kwon, H. J. & MQRES (International), M. (.

1/01/18 → 31/12/20

Project: Research

Overcoming antibiotic resistance: rapid discovery of new antibacterial drug targets using chemicalproteomics

Piggott, A., MQRES, M., MQRES (International), M. (. & Capon, R.

7/04/14 → …

Project: Research

A high performance liquid chromatography system for use in mass spectrometry-based biomolecular discovery

Haynes, P., Raftos, D., Cornish, J., Piggott, A. & Atwell, B.

1/01/16 → 31/12/16

Project: Research

Agilent 6130B/1260 LCMS System

Zakoshanski, I., Piggott, A., Karuso, P., Liu, F., Jamie, J., McRae, C., Try, A., Willows, R. & Jin, D.

1/01/15 → 31/12/15

Project: Research

Research Outputs

Biosynthesis of a novel benzazepine alkaloid nanangelenin A involves an unprecedented fungal NRPS that incorporates L-kynurenine and catalyzes a regioselective peptide cyclization

Li, H., Gilchrist, C. L. M., Phan, C., Lacey, H. J., Lacey, E., Piggott, A. & Chooi, Y. H., 13 Jan 2020.

Research output: Contribution to conference › Poster

    • Talauxins: hybrid phenalenone dimers from Talaromyces stipitatus

    Chaudhary, N. K., Crombie, A., Vuong, D., Lacey, E., Piggott, A. M. & Karuso, P., 24 Apr 2020, In : Journal of Natural Products. 83, 4, p. 1051-1060 10 p.

    Research output: Contribution to journal › Article

    • A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor

    Dekan, Z., Sianati, S., Yousuf, A., Sutcliffe, K. J., Gillis, A., Mallet, C., Singh, P., Jin, A. H., Wang, A. M., Mohammadi, S. A., Stewart, M., Ratnayake, R., Fontaine, F., Lacey, E., Piggott, A. M., Du, Y. P., Canals, M., Sessions, R. B., Kelly, E., Capon, R. J. & 2 others, Alewood, P. F. & Christie, M. J., 29 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22353-22358 6 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 4 Citations (Scopus)
    3 Downloads (Pure)

    Bipolenins K-N: new sesquiterpenoids from the fungal plant pathogen Bipolaris sorokiniana

    Phan, C-S., Li, H., Kessler, S., Solomon, P. S., Piggott, A. M. & Chooi, Y-H., 26 Aug 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 2020-2028 9 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 1 Citation (Scopus)
    3 Downloads (Pure)

    Bisindole alkaloids from a New Zealand deep-sea marine sponge Lamellomorpha strongylata

    Ragini, K., Piggott, A. M. & Karuso, P., Dec 2019, In : Marine Drugs. 17, 12, p. 1-14 14 p., 683.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 3 Downloads (Pure)