• 1061 Citations
  • 19 h-Index
20002020
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Personal profile

Biography

Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.

Qualifications

BMedScs (Hons) Macq, PhD Macq, MRACI CChem

Employment

2018 -Senior Lecturer, Macquarie University
2014 - 2017ARC Future Fellow, Macquarie University
2012 - 2014Senior Research Officer, IMB, The University of Queensland
2007 - 2012Research Officer, IMB, The University of Queensland
2005 - 2007Postdoctoral Research Fellow, Macquarie University

Research Interests

  • Discovery and development of next-generation antibiotics
  • Natural product mode of action
  • Biodiscovery and structure elucidation
  • Chemical biology using natural product probes

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Spectroscopic analysis Chemical Compounds
Aspergillus Chemical Compounds
Polyketides Chemical Compounds
Streptomyces Medicine & Life Sciences
Biosynthesis Chemical Compounds
spectroscopic analysis Physics & Astronomy
Porifera Medicine & Life Sciences
Fungi Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2020

Research Output 2000 2019

Discovery and heterologous biosynthesis of the burnettramic acids: rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettii

Li, H., Gilchrist, C. L. M., Lacey, H. J., Crombie, A., Vuong, D., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 8 Feb 2019, In : Organic Letters. 21, 5, p. 1287-1291 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Aspergillus
Aspergillus nidulans
biosynthesis
fungi
Biosynthesis

Predicting blood–brain barrier permeability of marine-derived kinase inhibitors using ensemble classifiers reveals potential hits for neurodegenerative disorders

Plisson, F. & Piggott, A. M., 29 Jan 2019, In : Marine Drugs. 17, 2, 23 p., 81.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Blood-Brain Barrier
Neurodegenerative Diseases
Permeability
Phosphotransferases
Central Nervous System Diseases

A study of the chemical diversity of macroalgae from South Eastern Australia

Vuong, D., Kaplan, M., Lacey, H. J., Crombie, A., Lacey, E. & Piggott, A. M., Apr 2018, In : Fitoterapia. 126, p. 53-64 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Seaweed
South Australia
Phaeophyta
Agrochemicals
Rhodophyta

Banksialactones and banksiamarins: isochromanones and isocoumarins from an Australian fungus, Aspergillus banksianus

Chaudhary, N. K., Pitt, J. I., Lacey, E., Crombie, A., Vuong, D., Piggott, A. M. & Karuso, P., 2018, In : Journal of Natural Products. 81, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Isocoumarins
Aspergillus
Metabolites
Fungi
Acids

Chemical ecogenomics-guided discovery of phytotoxic α-pyrones from the fungal wheat pathogen Parastagonospora nodorum

Li, H., Hu, J., Wei, H., Solomon, P. S., Vuong, D., Lacey, E., Stubbs, K. A., Piggott, A. M. & Chooi, Y. H., 2018, In : Organic Letters. 20, 19, p. 6148–6152 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Pyrones
Polyketide Synthases
Polyketides
Oxygenases
wheat