Projects per year
Personal profile
Biography
Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.
Qualifications
BMedScs (Hons) Macq, PhD Macq, MRACI CChem
Experience
| 2021 - | Associate Professor, Macquarie University |
| 2018 - 2020 | Senior Lecturer, Macquarie University |
| 2014 - 2017 | ARC Future Fellow, Macquarie University |
| 2012 - 2014 | Senior Research Officer, IMB, The University of Queensland |
| 2007 - 2012 | Research Officer, IMB, The University of Queensland |
| 2005 - 2007 | Postdoctoral Research Fellow, Macquarie University |
Research Interests
- Natural products chemistry
- Discovery and development of next-generation antibiotics
- Natural product mode of action
- Biodiscovery and structure elucidation
- Chemical biology using natural product probes
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Zombie spiders: exploring novel Australian entomopathogenic fungi and their bioactive secondary metabolites
Piggott, A., Jamie, J. & Valter, S.
24/11/23 → 23/11/26
Project: Research
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Effective fall armyworm pheromone blends for improved monitoring and population estimation in Australia
Mendez Alvarez, V., Park, S. J., Mainali, B., Liu, F., Piggott, A., Lee, R., Taylor, P., Ranganathan, S., Jabeen, A., Whitehouse, M., Walsh, T., Wee, T. T., Rane, R., Yonow, T., Bird, L., Miles, M., Spafford, H., Thistleton, B., Tadle, F. P., Stringer, L. D., Gregg, P. & del Soccorro, A.
11/05/22 → 15/05/25
Project: Research
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UWA led: CRISPR-based pathway activation for bioactive molecule discovery in fungi
Chooi, Y. H., Piggott, A. & Keller, N.
11/02/21 → 10/02/24
Project: Research
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Rapid Isolation System
Karuso, P., Taylor, P., Piggott, A., Liu, F., Jamie, J., Park, S. J., Jamie, I., Keaveney, S., Venkatesan, K. & Wong, D.
1/01/20 → 31/12/20
Project: Other
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Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a fungal carnitine O-acyltransferase domain
Arishi, A. A., Shang, Z., Lacey, E., Crombie, A., Vuong, D., Li, H., Bracegirdle, J., Turner, P., Lewis, W., Flematti, G. R., Piggott, A. M. & Chooi, Y. H., 7 Mar 2024, In: Chemical Science. 15, 9, p. 3349-3356 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)31 Downloads (Pure) -
Geministatins: new depside antibiotics from the fungus Austroacremonium gemini
Crombie, A., Kalaitzis, J. A., Chen, R., Vuong, D., Lacey, A. E., Lacey, E., Shivas, R. G., Tan, Y. P., Sbaraini, N., Chooi, Y. H. & Piggott, A. M., 26 Jun 2024, (E-pub ahead of print) In: Journal of Antibiotics. 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Heterologous biosynthesis of the sterol O-acyltransferase inhibitor helvamide unveils an α-ketoglutarate-dependent cross-linking oxygenase
Wang, R., Liang, J. J., Yang, W., Vuong, D., Kalaitzis, J. A., Lacey, A. E., Lacey, E., Piggott, A. M., Chooi, Y. H. & Li, H., 8 Mar 2024, In: Organic Letters. 26, 9, p. 1807-1812 6 p.Research output: Contribution to journal › Article › peer-review
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Self-resistance gene-guided discovery of the molecular basis for biosynthesis of the fatty acid synthase inhibitor cerulenin
Shang, Z., Arishi, A. A., Wu, C., Lao, F., Gilchrist, C. L. M., Moggach, S. A., Lacey, E., Piggott, A. M. & Chooi, Y. H., 6 Nov 2024, (E-pub ahead of print) In: Angewandte Chemie - International Edition. 11 p.Research output: Contribution to journal › Article › peer-review
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Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594
Lacey, A. E., Minns, S. A., Chen, R., Vuong, D., Lacey, E., Kalaitzis, J. A., Tan, Y. P., Shivas, R. G., Butler, M. S. & Piggott, A. M., Mar 2024, In: Journal of Antibiotics. 77, 3, p. 147–155 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)29 Downloads (Pure)
Prizes
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Faculty of Science and Engineering Award for Excellence in Innovative Research Partnership
Piggott, Andrew (Recipient), 6 Dec 2019
Prize
Press/Media
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CRC-P BioAustralis: Towards the Future
Andrew Piggott, Ernest Lacey, Yit Heng Chooi & Stephen W. Page
30/07/18 → 15/08/18
6 items of Media coverage
Press/Media: Research
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CRC-P The ProbioTICK Initiative
Andrew Piggott, Ernest Lacey, Peter Karuso & Fei Liu
27/10/17 → 3/11/17
5 items of Media coverage
Press/Media: Research