• 1123 Citations
  • 20 h-Index
20002020
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Personal profile

Biography

Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.

Qualifications

BMedScs (Hons) Macq, PhD Macq, MRACI CChem

Employment

2018 -Senior Lecturer, Macquarie University
2014 - 2017ARC Future Fellow, Macquarie University
2012 - 2014Senior Research Officer, IMB, The University of Queensland
2007 - 2012Research Officer, IMB, The University of Queensland
2005 - 2007Postdoctoral Research Fellow, Macquarie University

Research Interests

  • Discovery and development of next-generation antibiotics
  • Natural product mode of action
  • Biodiscovery and structure elucidation
  • Chemical biology using natural product probes

Fingerprint Dive into the research topics where Andrew Piggott is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Spectroscopic analysis Chemical Compounds
Aspergillus Chemical Compounds
Polyketides Chemical Compounds
Streptomyces Medicine & Life Sciences
Biosynthesis Chemical Compounds
Metabolites Chemical Compounds
spectroscopic analysis Physics & Astronomy
Porifera Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2020

Research Outputs 2000 2019

Discovery and heterologous biosynthesis of the burnettramic acids: rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettii

Li, H., Gilchrist, C. L. M., Lacey, H. J., Crombie, A., Vuong, D., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 8 Feb 2019, In : Organic Letters. 21, 5, p. 1287-1291 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Aspergillus
Aspergillus nidulans
biosynthesis
fungi
Biosynthesis

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system

Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Biosynthesis
Oxidoreductases
Genes
Chromosomes
Yeast

Predicting blood–brain barrier permeability of marine-derived kinase inhibitors using ensemble classifiers reveals potential hits for neurodegenerative disorders

Plisson, F. & Piggott, A. M., Feb 2019, In : Marine Drugs. 17, 2, 23 p., 81.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Blood-Brain Barrier
Neurodegenerative Diseases
Permeability
Phosphotransferases
Central Nervous System Diseases

The structure of testacein, a new hybrid polyketide-sesquiterpene metabolite from the lichen Notoparmelia testacea

Elix, J. A., Liao, L., Barrow, R. A. & Piggott, A. M., Jul 2019, In : Australasian Lichenology. 85, p. 34-39 6 p.

Research output: Contribution to journalArticleResearch

Open Access
File
Polyketides
Sesquiterpenes
Metabolites
Nuclear magnetic resonance spectroscopy
Mass spectrometry

A26771B: a forgotten antibiotic

Cowled, M. S., Lacey, E. & Piggott, A. M., 2018, Organic18 RACI Organic Division National Conference: conference program. p. 114 1 p. PT24

Research output: Chapter in Book/Report/Conference proceedingConference abstractResearch

Anti-Bacterial Agents
A26771B