Projects per year
Personal profile
Biography
Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.
Qualifications
BMedScs (Hons) Macq, PhD Macq, MRACI CChem
Employment
| 2018 - | Senior Lecturer, Macquarie University |
| 2014 - 2017 | ARC Future Fellow, Macquarie University |
| 2012 - 2014 | Senior Research Officer, IMB, The University of Queensland |
| 2007 - 2012 | Research Officer, IMB, The University of Queensland |
| 2005 - 2007 | Postdoctoral Research Fellow, Macquarie University |
Research Interests
- Discovery and development of next-generation antibiotics
- Natural product mode of action
- Biodiscovery and structure elucidation
- Chemical biology using natural product probes
Fingerprint Dive into the research topics where Andrew Piggott is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
Spectroscopic analysis
Chemical Compounds
Aspergillus
Chemical Compounds
Polyketides
Chemical Compounds
Streptomyces
Medicine & Life Sciences
Biosynthesis
Chemical Compounds
Metabolites
Chemical Compounds
spectroscopic analysis
Physics & Astronomy
Porifera
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2013 2020
Reverse Chemical Proteomics: Harnessing Yeast Display for Drug Discovery
Piggott, A., Karuso, P., Kwon, H. J. & MQRES (International), M. (.
1/01/18 → 31/12/20
Project: Research
Overcoming antibiotic resistance: rapid discovery of new antibacterial drug targets using chemicalproteomics
Piggott, A., MQRES, M., MQRES (International), M. (. & Capon, R.
7/04/14 → …
Project: Research
A high performance liquid chromatography system for use in mass spectrometry-based biomolecular discovery
Haynes, P., Raftos, D., Cornish, J., Piggott, A. & Atwell, B.
1/01/16 → 31/12/16
Project: Research
Agilent 6130B/1260 LCMS System
Zakoshanski, I., Piggott, A., Karuso, P., Liu, F., Jamie, J., McRae, C., Try, A., Willows, R. & Jin, D.
1/01/15 → 31/12/15
Project: Research
Yeast display as a platform technology to accelerate antiparasitic drug discovery and development
1/01/15 → 31/12/16
Project: Research
Research Outputs 2000 2019
A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor
Dekan, Z., Sianati, S., Yousuf, A., Sutcliffe, K. J., Gillis, A., Mallet, C., Singh, P., Jin, A. H., Wang, A. M., Mohammadi, S. A., Stewart, M., Ratnayake, R., Fontaine, F., Lacey, E., Piggott, A. M., Du, Y. P., Canals, M., Sessions, R. B., Kelly, E., Capon, R. J. & 2 others, 29 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22353-22358 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Opioid Peptides
mu Opioid Receptor
GTP-Binding Proteins
Analgesics
Fungi
Bipolenins K-N: new sesquiterpenoids from the fungal plant pathogen Bipolaris sorokiniana
Phan, C-S., Li, H., Kessler, S., Solomon, P. S., Piggott, A. M. & Chooi, Y-H., 26 Aug 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 2020-2028 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Pathogens
Biological Products
Seed
sativene
Discovery and heterologous biosynthesis of the burnettramic acids: rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettii
Li, H., Gilchrist, C. L. M., Lacey, H. J., Crombie, A., Vuong, D., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 8 Feb 2019, In : Organic Letters. 21, 5, p. 1287-1291 5 p.Research output: Contribution to journal › Article › Research › peer-review
Aspergillus
Aspergillus nidulans
biosynthesis
fungi
Biosynthesis
Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system
Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Biosynthesis
Oxidoreductases
Genes
Chromosomes
Yeast
Predicting blood–brain barrier permeability of marine-derived kinase inhibitors using ensemble classifiers reveals potential hits for neurodegenerative disorders
Plisson, F. & Piggott, A. M., Feb 2019, In : Marine Drugs. 17, 2, 23 p., 81.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Blood-Brain Barrier
Neurodegenerative Diseases
Permeability
Phosphotransferases
Central Nervous System Diseases