Projects per year
Personal profile
Biography
Research in my group spans the exciting and challenging interface between chemistry and biology. We are particularly interested in exploring the extraordinary chemical and structural diversity of natural products and using these molecules as new drug leads and as probes to elucidate biochemical and cellular pathways.
Qualifications
BMedScs (Hons) Macq, PhD Macq, MRACI CChem
Experience
| 2021 - | Associate Professor, Macquarie University |
| 2018 - 2020 | Senior Lecturer, Macquarie University |
| 2014 - 2017 | ARC Future Fellow, Macquarie University |
| 2012 - 2014 | Senior Research Officer, IMB, The University of Queensland |
| 2007 - 2012 | Research Officer, IMB, The University of Queensland |
| 2005 - 2007 | Postdoctoral Research Fellow, Macquarie University |
Research Interests
- Natural products chemistry
- Discovery and development of next-generation antibiotics
- Natural product mode of action
- Biodiscovery and structure elucidation
- Chemical biology using natural product probes
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Unlocking Australia's microbial secrets: new strategies for delivering next-generation antibiotics
Piggott, A. (Primary Chief Investigator), Vuong, D. (PhD Student) & Lacey, E. (Supervisor)
1/07/24 → 1/07/27
Project: Research
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HIA (Frontiers): Using artificial intelligence to develop automated monitoring systems for the banana and fruit spotting bugs
Park, S. J. (Primary Chief Investigator), Mainali, B. (Chief Investigator), Jiang, Y. (Chief Investigator), Jamie, J. (Chief Investigator), Trebicki, P. (Chief Investigator), Piggott, A. (Chief Investigator), Liu, F. (Chief Investigator) & Taylor, P. (Chief Investigator)
27/06/24 → 28/05/29
Project: Research
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Zombie spiders: exploring novel Australian entomopathogenic fungi and their bioactive secondary metabolites
Piggott, A. (Primary Chief Investigator), Jamie, J. (Supervisor) & Valter, S. (PhD Student)
24/11/23 → 23/11/26
Project: Research
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Effective fall armyworm pheromone blends for improved monitoring and population estimation in Australia
Mendez Alvarez, V. (Primary Chief Investigator), Park, S. J. (Chief Investigator), Mainali, B. (Chief Investigator), Liu, F. (Chief Investigator), Piggott, A. (Chief Investigator), Lee, R. (Chief Investigator), Taylor, P. (Chief Investigator), Ranganathan, S. (Chief Investigator), Jabeen, A. (Chief Investigator), Whitehouse, M. (Chief Investigator), Walsh, T. (Partner Investigator), Wee, T. T. (Partner Investigator), Rane, R. (Partner Investigator), Yonow, T. (Partner Investigator), Bird, L. (Partner Investigator), Miles, M. (Partner Investigator), Spafford, H. (Partner Investigator), Thistleton, B. (Partner Investigator), Tadle, F. P. (Partner Investigator), Stringer, L. D. (Partner Investigator), Gregg, P. (Partner Investigator) & del Soccorro, A. (Partner Investigator)
11/05/22 → 15/05/25
Project: Research
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UWA led: CRISPR-based pathway activation for bioactive molecule discovery in fungi
Chooi, Y. H. (Chief Investigator), Piggott, A. (Primary Chief Investigator) & Keller, N. (Partner Investigator)
11/02/21 → 10/02/24
Project: Research
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50-year-old mystery solved: how fungi made the ultimate fat-busting molecule
Shang, Z., Arishi, A. A., Wu, C., Lao, F., Gilchrist, C. L. M., Moggach, S. A., Lacey, E., Piggott, A. & Chooi, Y. H., Mar 2025, Chemistry in Australia, March 2025, p. 9 1 p.Research output: Contribution to Newspaper/Magazine/Website › Article
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Heterologous expression of an in planta-upregulated gene cluster in the wheat pathogen Parastagonospora nodorum establishes the biosynthesis of methylene-bridged depsides
Nguyen, H. T., Sbaraini, N., Bracegirdle, J., Smithers, L., Moggach, S. A., Vuong, D., Lacey, E., Solomon, P. S., Haywood, J., Piggott, A. M. & Chooi, Y.-H., 15 Oct 2025, In: Chemical Science. 16, 46, p. 21852-21861 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Self-resistance gene-guided discovery of the molecular basis for biosynthesis of the fatty acid synthase inhibitor cerulenin
Shang, Z., Arishi, A. A., Wu, C., Lao, F., Gilchrist, C. L. M., Moggach, S. A., Lacey, E., Piggott, A. M. & Chooi, Y. H., 10 Jan 2025, In: Angewandte Chemie - International Edition. 64, 2, p. 1-11 11 p., e202414941.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus) -
Transcriptomics-driven discovery of new meroterpenoid rhynchospenes involved in the virulence of the barley pathogen Rhynchosporium commune
Darma, R., Shang, Z., Bracegirdle, J., Moggach, S., McDonald, M. C., Piggott, A. M., Solomon, P. S. & Chooi, Y. H., 21 Feb 2025, In: ACS Chemical Biology. 20, 2, p. 421-431 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a fungal carnitine O-acyltransferase domain
Arishi, A. A., Shang, Z., Lacey, E., Crombie, A., Vuong, D., Li, H., Bracegirdle, J., Turner, P., Lewis, W., Flematti, G. R., Piggott, A. M. & Chooi, Y. H., 7 Mar 2024, In: Chemical Science. 15, 9, p. 3349-3356 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)46 Downloads (Pure)
Prizes
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25-Year Member of the Royal Australian Chemical Institute
Piggott, A. (Recipient), 2024
Prize: Other distinction
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Faculty of Science and Engineering Award for Excellence in Innovative Research Partnership
Piggott, A. (Recipient), 6 Dec 2019
Prize
Press/Media
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CRC-P BioAustralis: Towards the Future
Piggott, A., Lacey, E., Chooi, Y. H. & Page, S. W.
30/07/18 → 15/08/18
6 items of Media coverage
Press/Media: Research
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CRC-P The ProbioTICK Initiative
Piggott, A., Lacey, E., Karuso, P. & Liu, F.
27/10/17 → 3/11/17
5 items of Media coverage
Press/Media: Research