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20002020

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2019

A tetrapeptide class of biased analgesics from an Australian fungus targets the μ-opioid receptor

Dekan, Z., Sianati, S., Yousuf, A., Sutcliffe, K. J., Gillis, A., Mallet, C., Singh, P., Jin, A. H., Wang, A. M., Mohammadi, S. A., Stewart, M., Ratnayake, R., Fontaine, F., Lacey, E., Piggott, A. M., Du, Y. P., Canals, M., Sessions, R. B., Kelly, E., Capon, R. J. & 2 others, Alewood, P. F. & Christie, M. J., 29 Oct 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22353-22358 6 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
3 Downloads (Pure)

Bipolenins K-N: new sesquiterpenoids from the fungal plant pathogen Bipolaris sorokiniana

Phan, C-S., Li, H., Kessler, S., Solomon, P. S., Piggott, A. M. & Chooi, Y-H., 26 Aug 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 2020-2028 9 p.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)

Bisindole alkaloids from a New Zealand deep-sea marine sponge Lamellomorpha strongylata

Ragini, K., Piggott, A. M. & Karuso, P., Dec 2019, In : Marine Drugs. 17, 12, p. 1-14 14 p., 683.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)

Discovery and heterologous biosynthesis of the burnettramic acids: rare PKS-NRPS-derived bolaamphiphilic pyrrolizidinediones from an Australian fungus, Aspergillus burnettii

Li, H., Gilchrist, C. L. M., Lacey, H. J., Crombie, A., Vuong, D., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 8 Feb 2019, In : Organic Letters. 21, 5, p. 1287-1291 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system

Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
10 Downloads (Pure)

Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis

Lacey, H. J., Gilchrist, C. L. M., Crombie, A., Kalaitzis, J. A., Vuong, D., Rutledge, P. J., Turner, P., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 5 Nov 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 2631-2643 13 p.

Research output: Contribution to journalArticle

Open Access
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Open Access
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2 Citations (Scopus)
14 Downloads (Pure)

The structure of testacein, a new hybrid polyketide-sesquiterpene metabolite from the lichen Notoparmelia testacea

Elix, J. A., Liao, L., Barrow, R. A. & Piggott, A. M., Jul 2019, In : Australasian Lichenology. 85, p. 34-39 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Downloads (Pure)
2018

A study of the chemical diversity of macroalgae from South Eastern Australia

Vuong, D., Kaplan, M., Lacey, H. J., Crombie, A., Lacey, E. & Piggott, A. M., Apr 2018, In : Fitoterapia. 126, p. 53-64 12 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Banksialactones and banksiamarins: isochromanones and isocoumarins from an Australian fungus, Aspergillus banksianus

Chaudhary, N. K., Pitt, J. I., Lacey, E., Crombie, A., Vuong, D., Piggott, A. M. & Karuso, P., Jul 2018, In : Journal of Natural Products. 81, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Chemical ecogenomics-guided discovery of phytotoxic α-pyrones from the fungal wheat pathogen Parastagonospora nodorum

Li, H., Hu, J., Wei, H., Solomon, P. S., Vuong, D., Lacey, E., Stubbs, K. A., Piggott, A. M. & Chooi, Y. H., 5 Oct 2018, In : Organic Letters. 20, 19, p. 6148–6152 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Expanding antibiotic chemical space around the nidulin pharmacophore

Morshed, M. T., Vuong, D., Crombie, A., Lacey, A. E., Karuso, P., Lacey, E. & Piggott, A. M., 28 Apr 2018, In : Organic and Biomolecular Chemistry. 16, 16, p. 3038-3051 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Aspergillus hancockii sp. Nov., a biosynthetically talented fungus endemic to southeastern Australian soils

Pitt, J. I., Lange, L., Lacey, A. E., Vuong, D., Midgley, D. J., Greenfield, P., Bradbury, M. I., Lacey, E., Busk, P. K., Pilgaard, B., Chooi, Y-H. & Piggott, A. M., 5 Apr 2017, In : PLoS ONE. 12, 4, p. 1-21 21 p., e0170254.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
13 Downloads (Pure)

Crellasterones A and B: A-norsterol derivatives from the new caledonian sponge crella incrustans

Ragini, K., Piggott, A. M. & Karuso, P., 15 Jun 2017, In : Marine Drugs. 15, 6, p. 1-10 10 p., 177.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
9 Downloads (Pure)

Cyclization of linear tetrapeptides containing N-nethylated amino acids by using 1-propanephosphonic acid anhydride

Zhang, S., De Leon Rodriguez, L. M., Lacey, E., Piggott, A. M., Leung, I. K. H. & Brimble, M. A., 3 Jan 2017, In : European Journal of Organic Chemistry. 2017, 1, p. 149-158 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Enantiodivergence in the biosynthesis of bromotyrosine alkaloids from sponges?

Ragini, K., Fromont, J., Piggott, A. M. & Karuso, P., 27 Jan 2017, In : Journal of Natural Products. 80, 1, p. 215-219 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2016

Aspergillus sydowii marine fungal bloom in Australian coastal waters, its metabolites and potential impact on Symbiodinium dinoflagellates

Hayashi, A., Crombie, A., Lacey, E., Richardson, A. J., Vuong, D., Piggott, A. M. & Hallegraeff, G., 16 Mar 2016, In : Marine Drugs. 14, 3, p. 1-14 14 p., 59.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
12 Downloads (Pure)

Identifying the cellular targets of natural products using T7 phage display

Piggott, A. M. & Karuso, P., 1 May 2016, In : Natural Product Reports. 33, 5, p. 626-636 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Kumbicins A-D: Bis-Indolyl Benzenoids and Benzoquinones from an Australian Soil Fungus, Aspergillus kumbius

Lacey, H. J., Vuong, D., Pitt, J. I., Lacey, E. & Piggott, A. M., 2016, In : Australian Journal of Chemistry. 69, 2, p. 152-160 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Primary pH degradation products of doramectin

Moore, A. F., Lacey, H. J., Crombie, A., Lacey, E. & Piggott, A. M., 14 Sep 2016, In : Tetrahedron Letters. 57, 37, p. 4224-4227 4 p.

Research output: Contribution to journalArticle

2015

Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian Marine-Derived Streptomyces sp

Khalil, Z. G., Raju, R., Piggott, A. M., Salim, A. A., Blumenthal, A. & Capon, R. J., 24 Apr 2015, In : Journal of Natural Products. 78, 4, p. 949-952 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2014

Callyspongisines A-D: Bromopyrrole alkaloids from an Australian marine sponge, Callyspongia sp.

Plisson, F., Prasad, P., Xiao, X., Piggott, A. M., Huang, X. C., Khalil, Z. & Capon, R. J., 14 Mar 2014, In : Organic and Biomolecular Chemistry. 12, 10, p. 1579-1584 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Corymbia phloem phenolics, tannins and terpenoids: Interactions with a cerambycid borer

Hayes, R. A., Piggott, A. M., Smith, T. E. & Nahrung, H. F., 2014, In : Chemoecology. 24, 3, p. 95-103 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Mollemycin A: an antimalarial and antibacterial glyco-hexadepsipeptide- polyketide from an Australian marine-derived Streptomyces sp. (CMB-M0244)

Raju, R., Khalil, Z. G., Piggott, A. M., Blumenthal, A., Gardiner, D. L., Skinner-Adams, T. S. & Capon, R. J., 21 Mar 2014, In : Organic Letters. 16, 6, p. 1716-1719 4 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Rare Streptomyces sp. polyketides as modulators of K-Ras localisation

Salim, A. A., Xiao, X., Cho, K. J., Piggott, A. M., Lacey, E., Hancock, J. F. & Capon, R. J., 21 Jul 2014, In : Organic and Biomolecular Chemistry. 12, 27, p. 4872-4878 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Shornephine A: Structure, chemical stability, and P-glycoprotein inhibitory properties of a rare diketomorpholine from an Australian marine-derived Aspergillus sp.

Khalil, Z. G., Huang, X. C., Raju, R., Piggott, A. M. & Capon, R. J., 19 Sep 2014, In : Journal of Organic Chemistry. 79, 18, p. 8700-8705 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2013

Abyssomicins from the South China Sea deep-sea sediment verrucosispora sp. natural thioether michael addition adducts as antitubercular prodrugs

Wang, Q., Song, F., Xiao, X., Huang, P., Li, L., Monte, A., Abdel-Mageed, W. M., Wang, J., Guo, H., He, W., Xie, F., Dai, H., Liu, M., Chen, C., Xu, H., Liu, M., Piggott, A. M., Liu, X., Capon, R. J. & Zhang, L., 21 Jan 2013, In : Angewandte Chemie - International Edition. 52, 4, p. 1231-1234 4 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Australian marine sponge alkaloids as a new class of glycine-gated chloride channel receptor modulator

Balansa, W., Islam, R., Gilbert, D. F., Fontaine, F., Xiao, X., Zhang, H., Piggott, A. M., Lynch, J. W. & Capon, R. J., 15 Jul 2013, In : Bioorganic and Medicinal Chemistry. 21, 14, p. 4420-4425 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Nocardiopsins C and D and nocardiopyrone A: New polyketides from an Australian marine-derived Nocardiopsis sp.

Raju, R., Piggott, A. M., Quezada, M. & Capon, R. J., 14 Jan 2013, In : Tetrahedron. 69, 2, p. 692-698 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Sesterterpene glycinyl-lactams: a new class of glycine receptor modulator from Australian marine sponges of the genus Psammocinia

Balansa, W., Islam, R., Fontaine, F., Piggott, A. M., Zhang, H., Xiao, X., Webb, T. I., Gilbert, D. F., Lynch, J. W. & Capon, R. J., 28 Jul 2013, In : Organic and Biomolecular Chemistry. 11, 28, p. 4695-4701 7 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Sydowiols A-C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii

Liu, X., Song, F., Ma, L., Chen, C., Xiao, X., Ren, B., Liu, X., Dai, H., Piggott, A. M., Av-Gay, Y., Zhang, L. & Capon, R. J., 6 Nov 2013, In : Tetrahedron Letters. 54, 45, p. 6081-6083 3 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2012

Brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor

Song, F., Liu, X., Guo, H., Ren, B., Chen, C., Piggott, A. M., Yu, K., Gao, H., Wang, Q., Liu, M., Liu, X., Dai, H., Zhang, L. & Capon, R. J., 21 Sep 2012, In : Organic Letters. 14, 18, p. 4770-4773 4 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Design and application of in vivo FRET biosensors to identify protein prenylation and nanoclustering inhibitors

Köhnke, M., Schmitt, S., Ariotti, N., Piggott, A. M., Parton, R. G., Lacey, E., Capon, R. J., Alexandrov, K. & Abankwa, D., 27 Jul 2012, In : Chemistry and Biology. 19, 7, p. 866-874 9 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Heronamycin A: a new benzothiazine ansamycin from an Australian marine-derived Streptomyces sp.

Raju, R., Piggott, A. M., Khalil, Z., Bernhardt, P. V. & Capon, R. J., 29 Feb 2012, In : Tetrahedron Letters. 53, 9, p. 1063-1065 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Kinase Inhibitor Scaffolds against Neurodegenerative Diseases from a Southern Australian Ascidian, Didemnum sp.

Plisson, F., Conte, M., Khalil, Z., Huang, X. C., Piggott, A. M. & Capon, R. J., Jun 2012, In : ChemMedChem. 7, 6, p. 983-990 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Staurosporines disrupt phosphatidylserine trafficking and mislocalize ras proteins

Cho, K. J., Park, J. H., Piggott, A. M., Salim, A. A., Gorfe, A. A., Parton, R. G., Capon, R. J., Lacey, E. & Hancock, J. F., 21 Dec 2012, In : Journal of Biological Chemistry. 287, 52, p. 43573-43584 12 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Symphyocladins A-G: Bromophenol adducts from a Chinese marine red alga, Symphyocladia latiuscula

Xu, X., Piggott, A. M., Yin, L., Capon, R. J. & Song, F., 18 Apr 2012, In : Tetrahedron Letters. 53, 16, p. 2103-2106 4 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011

Ikirydinium A: a new indole alkaloid from the seeds of Hunteria umbellata (K. Schum)

Ajala, O. S., Piggott, A. M., Plisson, F., Khalil, Z., Huang, X. C., Adesegun, S. A., Coker, H. A. B. & Capon, R. J., 28 Dec 2011, In : Tetrahedron Letters. 52, 52, p. 7125-7127 3 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Nocardioazines: A novel bridged diketopiperazine scaffold from a marine-derived bacterium inhibits p-glycoprotein

Raju, R., Piggott, A. M., Huang, X. C. & Capon, R. J., 20 May 2011, In : Organic Letters. 13, 10, p. 2770-2773 4 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Reveromycins revealed: New polyketide spiroketals from Australian marine-derived and terrestrial Streptomyces spp. A case of natural products vs. artifacts

Fremlin, L., Farrugia, M., Piggott, A. M., Khalil, Z., Lacey, E. & Capon, R. J., 21 Feb 2011, In : Organic and Biomolecular Chemistry. 9, 4, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2010

9-(5-deoxy-5-thio - D-xylofuranosyl)adenine disulfide from the Southern Australian marine sponge trachycladus laevispirulifer: The first natural occurrence of a nucleoside disulfide

Peng, C., Gunaherath, G. M. K. B., Piggott, A. M., Khalil, Z., Conte, M. & Capon, R. J., 2010, In : Australian Journal of Chemistry. 63, 6, p. 873-876 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
38 Citations (Scopus)

Heronapyrroles A-C: Farnesylated 2-nitropyrroles from an Australian marine-derived Streptomyces sp.

Raju, R., Piggott, A. M., Barrientos Diaz, L. X., Khalil, Z. & Capon, R. J., 19 Nov 2010, In : Organic Letters. 12, 22, p. 5158-5161 4 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Ircinialactams: Subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae

Balansa, W., Islam, R., Fontaine, F., Piggott, A. M., Zhang, H., Webb, T. I., Gilbert, D. F., Lynch, J. W. & Capon, R. J., 15 Apr 2010, In : Bioorganic and Medicinal Chemistry. 18, 8, p. 2912-2919 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Nocardiopsins: New FKBP12-binding macrolide polyketides from an Australian marine-derived actinomycete, nocardiopsis sp

Raju, R., Piggott, A. M., Conte, M., Tnimov, Z., Alexandrov, K. & Capon, R. J., 8 Mar 2010, In : Chemistry - A European Journal. 16, 10, p. 3194-3200 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2009

Cottoquinazoline A and cotteslosins A and B, metabolites from an Australian marine-derived strain of Aspergillus versicolor

Fremlin, L. J., Piggott, A. M., Lacey, E. & Capon, R. J., 24 Apr 2009, In : Journal of Natural Products. 72, 4, p. 666-670 5 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Microbial biotransformation as a source of chemical diversity in cane toad steroid toxins

Hayes, R. A., Piggott, A. M., Dalle, K. & Capon, R. J., 15 Mar 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 6, p. 1790-1792 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Naseseazines A and B: a new dimeric diketopiperazine framework from a marine-derived actinomycete, Streptomyces sp

Raju, R., Piggott, A. M., Conte, M., Aalbersberg, W. G. L., Feussner, K. & Capon, R. J., 3 Sep 2009, In : Organic Letters. 11, 17, p. 3862-3865 4 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
10 Citations (Scopus)
2008
18 Citations (Scopus)