• 293 Citations
  • 6 h-Index
20082019

Research output per year

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Personal profile

Biography

Annika van Hummel completed her PhD in S100 proteins in osteoarthritis in 2014 under the supervision of Prof Hala Zreiqat and Prof Christopher Little at The University of Sydney. She then joined the Dementia Research Unit at The University of New South Wales working as a postdoctoral researcher with Prof Lars Ittner and moved to Macquarie University as part of the new Dementia Research Centre in December 2018.

Research interests

Since joining the Ittner group in 2014, Annika van Hummel has developed an interest in the use of genetically modified mice as models of neurodegenerative diseases (e.g. Motor Neuron Disease, Frontotemporal Dementia, Alzheimer's Disease), both to better understand the underlying cellular mechanisms and to test new treatment options.

Education/Academic qualification

PhD, University of Sydney

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Research Outputs

  • 293 Citations
  • 6 h-Index
  • 8 Article

Developmental expression of mutant PFN1 in motor neurons impacts neuronal growth and motor performance of young and adult mice

Brettle, M., Stefen, H., Djordjevic, A., Fok, S. Y. Y., Chan, J. W., van Hummel, A., van der Hoven, J., Przybyla, M., Volkerling, A., Ke, Y. D., Delerue, F., Ittner, L. M. & Fath, T., 27 Sep 2019, In : Frontiers in Molecular Neuroscience. 12, p. 1-12 12 p., 231.

Research output: Contribution to journalArticle

Open Access
File
  • Selective spatiotemporal vulnerability of central nervous system neurons to pathologic TAR DNA-binding protein 43 in aged transgenic mice

    van Hummel, A., Chan, G., van der Hoven, J., Morsch, M., Ippati, S., Suh, L., Bi, M., Asih, P. R., Lee, W. S., Butler, T. A., Przybyla, M., Halliday, G. M., Piguet, O., Kiernan, M. C., Chung, R. S., Ittner, L. M. & Ke, Y. D., 1 Jun 2018, In : American Journal of Pathology. 188, 6, p. 1447-1456 10 p.

    Research output: Contribution to journalArticle

  • 1 Citation (Scopus)

    Tau exacerbates excitotoxic brain damage in an animal model of stroke

    Bi, M., Gladbach, A., van Eersel, J., Ittner, A., Przybyla, M., van Hummel, A., Chua, S. W., van der Hoven, J., Lee, W. S., Müller, J., Parmar, J., von Jonquieres, G., Stefen, H., Guccione, E., Fath, T., Housley, G. D., Klugmann, M., Ke, Y. D. & Ittner, L. M., 1 Dec 2017, In : Nature Communications. 8, 1, p. 1-15 15 p., 473.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 34 Citations (Scopus)
    18 Downloads (Pure)

    Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia

    Przybyla, M., Stevens, C. H., van der Hoven, J., Harasta, A., Bi, M., Ittner, A., van Hummel, A., Hodges, J. R., Piguet, O., Karl, T., Kassiou, M., Housley, G. D., Ke, Y. D., Ittner, L. M. & Eersel, J. V., 19 Sep 2016, In : Neuroscience Letters. 631, p. 24-29 6 p.

    Research output: Contribution to journalArticle

  • 15 Citations (Scopus)

    No overt deficits in aged tau-deficient C57Bl/6.Mapttm1(EGFP)kit GFP knockin mice

    Van Hummel, A., Bi, M., Ippati, S., van der Hoven, J., Volkerling, A., Lee, W. S., Tan, D. C. S., Bongers, A., Ittner, A., Ke, Y. D. & Ittner, L. M., 13 Oct 2016, In : PLoS ONE. 11, 10, p. 1-14 14 p., e0163236.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 16 Citations (Scopus)
    2 Downloads (Pure)