Projects per year
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Papillomaviridae
Medicine & Life Sciences
Breast Neoplasms
Medicine & Life Sciences
Quinolinic Acid
Medicine & Life Sciences
Kynurenine
Medicine & Life Sciences
Astrocytes
Medicine & Life Sciences
Mouse mammary tumor virus
Medicine & Life Sciences
Glioblastoma
Medicine & Life Sciences
Indoleamine-Pyrrole 2,3,-Dioxygenase
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2016 2017
Unravelling the ability of a metabolic pathway to suppress normal immune system function in brain cancer
Adams, S., Guillemin, G., McDonald, K., Teo, C., Zaunders, J., Jones, S., Sedger, L., Bustamante, S., Turner, J., Heng, R. & Sundaram, G.
8/12/16 → …
Project: Research
"Re-educating" immune cells as a combination therapy to limit breast cancer metastasis
1/01/16 → 1/01/17
Project: Research
Research Outputs 2009 2019
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
Halloran, M., Ragagnin, A. M. G., Vidal, M., Parakh, S., Yang, S., Heng, B., Grima, N., Shahheydari, H., Soo, K-Y., Blair, I., Guillemin, G. J., Sundaramoorthy, V. & Atkin, J. D., 4 Dec 2019, In : Cellular and Molecular Life Sciences. 15 p.Research output: Contribution to journal › Article › Research › peer-review
Endoplasmic Reticulum Stress
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum
Protein Transport
Endoplasmic Reticulum-Associated Degradation
Neuroprotective effect of myxobacterial extracts on quinolinic acid-induced toxicity in primary human neurons
Dehhaghi, M., Tan, V., Heng, B., Braidy, N., Mohammadipanah, F. & Guillemin, G. J., Feb 2019, In : Neurotoxicity Research. 35, 2, p. 281-290 10 p.Research output: Contribution to journal › Article › Research › peer-review
Quinolinic Acid
Neuroprotective Agents
Neurons
Toxicity
Stigmatella
Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor
Engel, M., Gee, Y. S., Cross, D., Maccarone, A., Heng, B., Hulme, A., Smith, G., Guillemin, G. J., Stringer, B. W., Hyland, C. J. T. & Ooi, L., 1 May 2019, In : Journal of Neurochemistry. 149, 4, p. 535-550 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Histone Demethylases
Prodrugs
Glioblastoma
Lysine
Glutathione
Protective effects of myxobacterial extracts on hydrogen peroxide-induced toxicity on human primary astrocytes
Dehhaghi, M., Tan, V., Heng, B., Mohammadipanah, F. & Guillemin, G. J., 10 Feb 2019, In : Neuroscience. 399, p. 1-11 11 p.Research output: Contribution to journal › Article › Research › peer-review
Astrocytes
Hydrogen Peroxide
Oxidative Stress
Cell Death
Myxococcales
Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes
Tran, C., Heng, B., Teo, J. D., Humphrey, S. J., Qi, Y., Couttas, T. A., Stefen, H., Brettle, M., Fath, T., Guillemin, G. J. & Don, A. S., 19 Nov 2019, In : Journal of Neurochemistry. 16 p., e14917.Research output: Contribution to journal › Article › Research › peer-review
Cell death
Gene expression
Astrocytes
Neurons
Cell Death