• 572 Citations
  • 12 h-Index
20092020

Research output per year

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Research Outputs

  • 572 Citations
  • 12 h-Index
  • 25 Article
  • 2 Meeting abstract
  • 2 Letter
  • 1 Review article
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Article
2020

Sphingosine 1-phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

Tran, C., Heng, B., Teo, J. D., Humphrey, S. J., Qi, Y., Couttas, T. A., Stefen, H., Brettle, M., Fath, T., Guillemin, G. J. & Don, A. S., Apr 2020, In : Journal of Neurochemistry. 153, 2, p. 173-188 16 p., e14917.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2019

Neuroprotective effect of myxobacterial extracts on quinolinic acid-induced toxicity in primary human neurons

Dehhaghi, M., Tan, V., Heng, B., Braidy, N., Mohammadipanah, F. & Guillemin, G. J., Feb 2019, In : Neurotoxicity Research. 35, 2, p. 281-290 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor

Engel, M., Gee, Y. S., Cross, D., Maccarone, A., Heng, B., Hulme, A., Smith, G., Guillemin, G. J., Stringer, B. W., Hyland, C. J. T. & Ooi, L., 1 May 2019, In : Journal of Neurochemistry. 149, 4, p. 535-550 16 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
6 Downloads (Pure)

Protective effects of myxobacterial extracts on hydrogen peroxide-induced toxicity on human primary astrocytes

Dehhaghi, M., Tan, V., Heng, B., Mohammadipanah, F. & Guillemin, G. J., 10 Feb 2019, In : Neuroscience. 399, p. 1-11 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sphingosine kinase 2 potentiates amyloid deposition but protects against hippocampal volume loss and demyelination in a mouse model of Alzheimer's disease

Lei, M., Teo, J. D., Song, H., McEwen, H. P., Yup Lee, J., Couttas, T. A., Duncan, T., Chesworth, R., Bertz, J., Przybyla, M., Van Eersel, J., Heng, B., Guillemin, G. J., Ittner, L. M., Fath, T., Garner, B., Ittner, A., Karl, T. & Don, A. S., 27 Nov 2019, In : The Journal of Neuroscience. 39, 48, p. 9645-9659 15 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)
2017

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s)

Guo, F., Hu, M., Huang, D., Zhao, Y., Heng, B., Guillemin, G., Lim, C. K., Hawthorne, W. J. & Yi, S., Oct 2017, In : Xenotransplantation. 24, 5, p. 1-11 11 p., e12326.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Genetic basis of hindlimb loss in a naturally occurring vertebrate model

Don, E. K., De Jong-Curtain, T. A., Doggett, K., Hall, T. E., Heng, B., Badrock, A. P., Winnick, C., Nicholson, G. A., Guillemin, G. J., Currie, P. D., Hesselson, D., Heath, J. K. & Cole, N. J., 15 Mar 2016, In : Biology Open. 5, 3, p. 359-366 8 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
1 Downloads (Pure)

Keratin 14 expression in epithelial progenitor cells of the developing human cornea

Eghtedari, Y., Richardson, A., Mai, K., Heng, B., Guillemin, G. J., Wakefield, D. & Di Girolamo, N., 1 May 2016, In : Stem Cells and Development. 25, 9, p. 699-711 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66

An, H., Brettle, M., Lee, T., Heng, B., Lim, C. K., Guillemin, G. J., Lord, M. S., Klotzsch, E., Geczy, C. L., Bryant, K., Fath, T. & Tedla, N., 2016, In : Journal of Cell Science. 129, 6, p. 1198-1209 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Synergistic induction of CXCL10 by interferon-gamma and lymphotoxin-alpha in astrocytes: Possible role in cerebral malaria

Bakmiwewa, S. M., Weiser, S., Grey, M., Heng, B., Guillemin, G. J., Ball, H. J. & Hunt, N. H., 1 Feb 2016, In : Cytokine. 78, p. 79-86 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Understanding the role of the kynurenine pathway in human breast cancer immunobiology

Heng, B., Lim, C. K., Lovejoy, D. B., Bessede, A., Gluch, L. & Guillemin, G. J., 9 Feb 2016, In : Oncotarget. 7, 6, p. 6506-6520 15 p.

Research output: Contribution to journalArticle

Open Access
File
54 Citations (Scopus)
25 Downloads (Pure)
2015

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Yan, E. B., Frugier, T., Lim, C. K., Heng, B., Sundaram, G., Tan, M., Rosenfeld, J. V., Walker, D. W., Guillemin, G. J. & Morganti-Kossmann, M. C., 30 May 2015, In : Journal of Neuroinflammation. 12, p. 1-17 17 p., 110.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
5 Downloads (Pure)

An effective, low-cost method for achieving and maintaining hypoxia during cell culture studies

Bakmiwewa, S. M., Heng, B., Guillemin, G. J., Ball, H. J. & Hunt, N. H., 1 Oct 2015, In : BioTechniques. 59, 4, p. 223-229 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2

Gurgis, F. M. S., Åkerfeldt, M. C., Heng, B., Wong, C., Adams, S., Guillemin, G. J., Johns, T. G., Chircop, M. & Munoz, L., 2015, In : Cell Death Discovery. 1, p. 1-11 11 p., 15028.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
15 Downloads (Pure)

Human Papilloma viruses and breast cancer

Lawson, J. S., Glenn, W. K., Salyakina, D., Delprado, W., Clay, R., Antonsson, A., Heng, B., Miyauchi, S., Tran, D. D., Ngan, C. C., Lutze-Mann, L. & Whitaker, N. J., 16 Dec 2015, In : Frontiers in Oncology. 5, p. 1-12 12 p., 277.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Lycopene pretreatment ameliorates acute ethanol induced NAD(+) depletion in human astroglial cells

Guest, J., Guillemin, G. J., Heng, B. & Grant, R., 2015, In : Oxidative Medicine and Cellular Longevity. 2015, p. 1-8 8 p., 741612.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
10 Downloads (Pure)

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation

Munoz, L., Kavanagh, M. E., Phoa, A. F., Heng, B., Dzamko, N., Chen, E. J., Doddareddy, M. R., Guillemin, G. J. & Kassiou, M., 5 May 2015, In : European Journal of Medicinal Chemistry. 95, p. 29-34 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The p38-MK2-HuR pathway potentiates EGFRvIII-IL-1β-driven IL-6 secretion in glioblastoma cells

Gurgis, F. M. S., Yeung, Y. T., Tang, M. X. M., Heng, B., Buckland, M., Ammit, A. J., Haapasalo, J., Haapasalo, H., Guillemin, G. J., Grewal, T. & Munoz, L., 28 May 2015, In : Oncogene. 34, 22, p. 2934-2942 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)
2013

Characterization of the Kynurenine pathway and quinolinic acid production in macaque macrophages

Lim, C. K., Yap, M. M. C., Kent, S. J., Gras, G., Samah, B., Batten, J. C., De Rose, R., Heng, B., Brew, B. J. & Guillemin, G. J., 2013, In : International Journal of Tryptophan Research. 6, p. 7-19 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
20 Downloads (Pure)

Detecting human papillomavirus in ocular surface diseases

Woods, M., Chow, S., Heng, B., Glenn, W., Whitaker, N., Waring, D., Iwasenko, J., Rawlinson, W., Coroneo, M. T., Wakefield, D. & Di Girolamo, N., 19 Nov 2013, In : Investigative Ophthalmology and Visual Science. 54, 13, p. 8069-8078 10 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2012

Epstein-Barr Virus, Human Papillomavirus and Mouse Mammary Tumour Virus as Multiple Viruses in Breast Cancer

Glenn, W. K., Heng, B., Delprado, W., Iacopetta, B., Whitaker, N. J. & Lawson, J. S., 19 Nov 2012, In : PLoS ONE. 7, 11, p. 1-10 10 p., e48788.

Research output: Contribution to journalArticle

88 Citations (Scopus)
2010

Mouse mammary tumor virus-like sequences in human breast cancer

Lawson, J. S., Glenn, W. K., Salmons, B., Ye, Y., Heng, B., Moody, P., Johal, H., Rawlinson, W. D., Delprado, W., Lutze-Mann, L. & Whitaker, N. J., 1 May 2010, In : Cancer Research. 70, 9, p. 3576-3585 10 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2009

Human papilloma virus is associated with breast cancer

Heng, B., Glenn, W. K., Ye, Y., Tran, B., Delprado, W., Lutze-Mann, L., Whitaker, N. J. & Lawson, J. S., 20 Oct 2009, In : British Journal of Cancer. 101, 8, p. 1345-1350 6 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Koilocytes indicate a role for human papilloma virus in breast cancer

Lawson, J. S., Glenn, W. K., Heng, B., Ye, Y., Tran, B., Lutze-Mann, L. & Whitaker, N. J., 20 Oct 2009, In : British Journal of Cancer. 101, 8, p. 1351-1356 6 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)