Cara Hildreth

Dr

  • 289 Citations
  • 12 h-Index
20082019
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Research Outputs 2008 2019

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Article
2019

Increased excitatory regulation of the hypothalamic paraventricular nucleus and circulating vasopressin results in the hypertension observed in polycystic kidney disease

Underwood, C. F., Boyd, R., Phillips, J. K. & Hildreth, C. M., 1 Jan 2019, In : Journal of Hypertension. 37, 1, p. 109-115 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycystic Kidney Diseases
Paraventricular Hypothalamic Nucleus
Vasopressins
Hypertension
Baroreflex
Deglutition
Central Pattern Generators
Neurons
Personnel Selection
Swallows

Respiratory sympathetic modulation is augmented in chronic kidney disease

Saha, M., Menuet, C., Sun, Q. J., Burke, P. G. R., Hildreth, C. M., Allen, A. M. & Phillips, J. K., 1 Apr 2019, In : Respiratory Physiology and Neurobiology. 262, p. 57-66 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycystic Kidney Diseases
Chronic Renal Insufficiency
Hypercapnia
Area Under Curve
Splanchnic Nerves
2018

Effect of anaesthetic and choice of neuromuscular blocker on vagal control of heart rate under laboratory animal experimental conditions

Kandukuri, D. S., Phillips, J. K., Tahmindjis, M. & Hildreth, C. M., Jun 2018, In : Laboratory Animals. 52, 3, p. 280-291 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Neuromuscular Blocking Agents
Laboratory Animals
anesthetics
laboratory animals
Anesthetics

Osmoregulation in polycystic kidney disease: relationship with cystogenesis and hypertension

Underwood, C. F., Phillips, J. K. & Hildreth, C. M., 1 Jun 2018, In : Annals of Nutrition and Metabolism. 72, suppl 2, p. 33-38 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Osmoregulation
Polycystic Kidney Diseases
Vasopressins
Hypertension
Dehydration
2016

Tonically active cAMP-dependent signaling in the ventrolateral medulla regulates sympathetic and cardiac vagal outflows

Tallapragada, V. J., Hildreth, C. M., Burke, P. G. R., Raley, D. A., Hassan, S. F., McMullan, S. & Goodchild, A. K., 1 Feb 2016, In : Journal of Pharmacology and Experimental Therapeutics. 356, 2, p. 424-433 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Cyclic AMP
Splanchnic Nerves
Cyclic AMP-Dependent Protein Kinases
Heart Rate
Baroreflex
2015

Abnormal central control underlies impaired baroreflex control of heart rate and sympathetic nerve activity in female Lewis polycystic kidney rats

Salman, I. M., Phillips, J. K., Ameer, O. Z. & Hildreth, C. M., Jul 2015, In : Journal of Hypertension. 33, 7, p. 1418-1428 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycystic Kidney Diseases
Baroreflex
Heart Rate
Reflex
Vagus Nerve Stimulation

Direct conscious telemetry recordings demonstrate increased renal sympathetic nerve activity in rats with chronic kidney disease

Salman, I. M., Kandukuri, D. S., Harrison, J. L., Hildreth, C. M. & Phillips, J. K., 2015, In : Frontiers in Physiology. 6, p. 1-10 10 p., 218.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Telemetry
Chronic Renal Insufficiency
Kidney
Arterial Pressure
Polycystic Kidney Diseases

The effect of losartan on differential reflex control of sympathetic nerve activity in chronic kidney disease

Yao, Y., Hildreth, C. M., Farnham, M. M., Saha, M., Sun, Q. J., Pilowsky, P. M. & Phillips, J. K., 6 Jun 2015, In : Journal of Hypertension. 33, 6, p. 1249-1260 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycystic Kidney Diseases
Losartan
Chronic Renal Insufficiency
Reflex
Viscera
2014

Differential contribution of afferent and central pathways to the development of baroreflex dysfunction in chronic kidney disease

Salman, I. M., Hildreth, C. M., Ameer, O. Z. & Phillips, J. K., 2014, In : Hypertension. 63, 4, p. 804-810 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Afferent Pathways
Baroreflex
Polycystic Kidney Diseases
Chronic Renal Insufficiency
Kidney

Sympathetic overactivity prevails over the vascular amplifier phenomena in a chronic kidney disease rat model of hypertension

Ameer, O. Z., Hildreth, C. M. & Phillips, J. K., 2014, In : Physiological Reports. 2, 11, p. 1-11 11 p., e12205.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Polycystic Kidney Diseases
Hexamethonium
Chronic Renal Insufficiency
Blood Vessels
Inbred SHR Rats
2013

Temporal development of baroreceptor dysfunction in a rodent model of chronic kidney disease

Hildreth, C. M., Kandukuri, D. S., Goodchild, A. K. & Phillips, J. K., Jul 2013, In : Clinical and Experimental Pharmacology and Physiology. 40, 7, p. 458-465 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Pressoreceptors
Chronic Renal Insufficiency
Baroreflex
Rodentia
Blood Pressure
2012

Prognostic indicators of cardiovascular risk in renal disease

Hildreth, C. M., 2012, In : Frontiers in Physiology. 2, p. 1-6 6 p., Article 121.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Chronic Kidney Failure
Kidney
Pressoreceptors
Baroreflex
Heart Rate
2011
Cystic Kidney Diseases
Polycystic Kidney Diseases
Pulse Wave Analysis
Perindopril
Angiotensin-Converting Enzyme Inhibitors

Aortic stiffness is associated with vascular calcification and remodeling in a chronic kidney disease rat model

Ng, K., Hildreth, C. M., Phillips, J. K. & Avolio, A. P., Jun 2011, In : American Journal of Physiology - Renal Physiology. 300, 6, p. F1431-F1436 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Vascular Calcification
Polycystic Kidney Diseases
Pulse Wave Analysis
Vascular Stiffness
Chronic Renal Insufficiency
2010

Cardiovascular autonomic dysfunction in a novel rodent model of polycystic kidney disease

Harrison, J. L., Hildreth, C. M., Callahan, S. M., Goodchild, A. K. & Phillips, J. K., 15 Jan 2010, In : Autonomic Neuroscience: Basic and Clinical. 152, 1-2, p. 60-66 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycystic Kidney Diseases
Baroreflex
Rodentia
Hypertension
Blood Pressure

Role of ionotropic GABA, glutamate and glycine receptors in the tonic and reflex control of cardiac vagal outflow in the rat

Hildreth, C. M. & Goodchild, A. K., Oct 2010, In : BMC Neuroscience. 11, p. 1-11 11 p., 128.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Glycine Receptors
Ionotropic Glutamate Receptors
GABA Receptors
Bradycardia
Reflex
2008

Control of sympathetic, respiratory and somatomotor outflow by an intraspinal pattern generator

Goodchild, A. K., Van Deurzen, B. T. M., Hildreth, C. M. & Pilowsky, P. M., Apr 2008, In : Clinical and Experimental Pharmacology and Physiology. 35, 4, p. 447-453 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Bicuculline
GABA-A Receptors
Phrenic Nerve
Diaphragm
Spinal Cord

Impaired serotonergic regulation of heart rate may underlie reduced baroreflex sensitivity in an animal model of depression

Hildreth, C. M., Padley, J. R., Pilowsky, P. M. & Goodchild, A. K., 1 Jan 2008, In : American Journal of Physiology - Heart and Circulatory Physiology. 294, 1, p. H474-H480 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Baroreflex
Animal Models
Heart Rate
Depression
Reflex

Metabotropic neurotransmission and integration of sympathetic nerve activity by the rostral ventrolateral medulla in the rat

Pilowsky, P. M., Abbott, S. B., Burke, P. G. R., Farnham, M. M. J., Hildreth, C. M., Kumar, N. N., Li, Q., Lonergan, T., McMullan, S., Spirovski, D. & Goodchild, A. K., Apr 2008, In : Clinical and Experimental Pharmacology and Physiology. 35, 4, p. 508-511 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Motor Neurons
Synaptic Transmission
Neurotransmitter Agents
Reflex
Medulla Oblongata