Projects per year
Personal profile
Biography
My PhD focused on investigating strategies of genetic biocontrol of invasive vertebrates. This involved the generation and testing of several CRISPR/Cas-based gene drives in mice. Further research during my PhD involved the development of all-in-one plasmids for CRISPR genome editing.
Research interests
My current research continues in the field of genetic biocontrol of invasive vertebrates, moving over to zebrafish as a model organism. Here I am working on engineered genetic incompatibilities (EGIs), a method of synthetic speciation.
Education/Academic qualification
Molecular Biology, PhD, CRISPR Technology Development: Gene Drives and Genome Editing, The University of Adelaide
2016 → 2020
Award Date: 3 Dec 2020
BSc (Molecular Biology), The University of Adelaide
2013 → 2015
Bachelor of Computer Science, The University of Adelaide
2001 → 2006
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Phase II: Proof of concept for genetic biocontrol in a vertebrates through a Fish Model Species
Maselko, M. (Primary Chief Investigator), Pfitzner, C. (Chief Investigator), Sunarto, A. (Chief Investigator), Morsch, M. (Chief Investigator), Chung, R. (Chief Investigator), Strive, T. (Chief Investigator) & Tizard, M. (Chief Investigator)
14/01/23 → 13/01/24
Project: Research
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Methylmercury demethylation and volatilization by animals expressing microbial enzymes
Tepper, K., King, J., Manuneedhi Cholan, P., Pfitzner, C., Morsch, M., Apte, S. C. & Maselko, M., 12 Feb 2025, In: Nature Communications. 16, 1, p. 1-10 10 p., 1117.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)50 Downloads (Pure) -
Optimal SpCas9- and SaCas9-mediated gene editing by enhancing gRNA transcript levels through scaffold poly-T tract reduction
Chey, Y. C. J., Gierus, L., Lushington, C., Arudkumar, J. C., Geiger, A. B., Staker, L. G., Robertson, L. J., Pfitzner, C., Kennedy, J. G., Lee, R. H. B., Godahewa, G. I., Adikusuma, F. & Thomas, P. Q., 12 Feb 2025, In: BMC Genomics. 26, 1, p. 1-12 12 p., 138.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)55 Downloads (Pure) -
Mapping combinatorial expression of non-clustered protocadherins in the developing brain identifies novel PCDH19-mediated cell adhesion properties
Mincheva-Tasheva, S., Pfitzner, C., Kumar, R., Kurtsdotter, I., Scherer, M., Ritchie, T., Muhr, J., Gecz, J. & Thomas, P. Q., Apr 2024, In: Open Biology. 14, 4, p. 1-13 13 p., 230383.Research output: Contribution to journal › Article › peer-review
Open AccessFile47 Downloads (Pure) -
Rapid generation and screening of transgenic black soldier fly (Hermetia illucens)
Pfitzner, C., Tepper, K., Kumar, S., Retief, C., McNab, J. M., Harrell, R. A. & Maselko, M., 22 Feb 2024, (Submitted) (bioRxiv).Research output: Working paper › Preprint
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Methylmercury demethylation and volatilization by animals expressing microbial enzymes
Tepper, K., King, J., Cholan, P. M., Pfitzner, C., Morsch, M., Apte, S. C. & Maselko, M., 18 Dec 2023, (Submitted) (bioRxiv).Research output: Working paper › Preprint
Prizes
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Dean's Commendation for Doctoral Thesis Excellence
Pfitzner, C. (Recipient), 2020
Prize: Honorary award