• 1138 Citations
  • 18 h-Index
1991 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

My Education and work experience reflect two of my main passions in life, Science and the Environment. I have written over 30 Publications on these topics and have presented my work both nationally and internationally as both posters and oral presentations. I obtained my PhD in Neuroscience in December 2014 from the University of Calgary's faculty of Medicine.

The focus of my thesis was pain, epilepsy and ion channel physiology, with a view to understanding the interactions between drugs and ion channels so that cures and better therapies can be developed for the numerous diseases associated with ion channels (Channelopathies).

My skills include; extensive experience in Electrophysiology, Molecular biology and Biochemistry, obtained during the many years I have spent in both Academia and Industry.

My new position at Macquarie University will build on this expertise by studying Drug/Ion Channel physiology, with an emphasis on developing novel Cannabinoid-based therapies that will regulate abnormal ion channel activity associated with epilepsy, pain and other diseases. 250,000 Australians currently live with epilepsy, and chronic pain costs Australian healthcare more than cancer, heart disease and HIV combined. Drugs that target ion channels is a multibillion-dollar industry due to their effectiveness in treating diseases. This project aims to identify selective and potent cannabinoids and define their mode of action on ion channels by electrophysiology and molecular biology approaches.

My other passion is for Ecology and Environmental and Health Management. I recently graduated from the U of Calgary environmental management certification program which complimented my undergraduate background from Wales in Ecology. I used both my scientific and environmental background to help tackle some of the major environmental problems associated with Northern Alberta’s Oilsands mining industry, in particular, cleaning-up the vast tailings ponds created by this industry.  

Education/Academic qualification

Environmental management, Certified, University of Calgary

3 Jan 20151 Jun 2017

Neuroscience, PhD, University of Calgary

1 May 20108 Dec 2014

Freshwater ecology, B.Sc., University of Wales

7 Sep 198726 Jun 1990

Fingerprint Dive into the research topics where Chris Bladen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

Research Outputs

  • 1138 Citations
  • 18 h-Index
  • 28 Article
  • 1 Comment/opinion

Differential activation of G protein-mediated signaling by synthetic cannabinoid receptor agonists

Sachdev, S., Banister, S. D., Santiago, M., Bladen, C., Kassiou, M. & Connor, M., 1 Apr 2020, In : Pharmacology Research & Perspectives. 8, 2, p. 1-10 10 p., e00566.

Research output: Contribution to journalArticle

Open Access
File
  • 3 Downloads (Pure)

    Regulation of heterologously expressed 5-HT1B receptors coupling to potassium channels in AtT-20 cells

    Heblinski, M., Bladen, C. & Connor, M., 1 Feb 2019, In : British Journal of Pharmacology. 176, 3, p. 451-465 15 p.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    Differential modulation of NMDA and AMPA receptors by cellular prion protein and copper ions

    Huang, S., Chen, L., Bladen, C., Stys, P. K. & Zamponi, G. W., 25 Oct 2018, In : Molecular Brain. 11, 1, p. 1-6 6 p., 62.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 4 Citations (Scopus)
    3 Downloads (Pure)

    Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi

    Sousa, S. R., Wingerd, J. S., Brust, A., Bladen, C., Ragnarsson, L., Herzig, V., Deuis, J. R., Dutertre, S., Vetter, I., Zamponi, G. W., King, G. F., Alewood, P. F. & Lewis, R. J., 1 Sep 2017, In : PLoS ONE. 12, 9, p. 1-22 22 p., e0182848.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 7 Citations (Scopus)
    9 Downloads (Pure)

    1,4-Dihydropyridine derivatives with T-type calcium channel blocking activity attenuate inflammatory and neuropathic pain.

    Bladen, C., Gadotti, V. M., Gündüz, M. G., Berger, N. D., Şimşek, R., Şafak, C. & Zamponi, G. W., 1 Jun 2015, In : Pflugers Archiv European Journal of Physiology. 467, 6, p. 1237-1247 11 p.

    Research output: Contribution to journalArticle

  • 28 Citations (Scopus)