Personal profile
Biography
Daryl completed her PhD at UNSW Sydney in the field of synthetic organic chemistry. Currently, Daryl is a research fellow in the Dementia Research Centre, Macquarie University. Her current research focuses on developing peptide therapeutics and small molecules for Alzheimer's Disease. Her drug development approach combines computational chemistry and organic synthesis.
Education/Academic qualification
Chemistry, PhD, Exploiting the Fluorine Gauche Effect for Applications in Medicinal and Supramolecular Chemistry, The University of New South Wales
Mar 2015 → Jan 2019
Award Date: 31 Jan 2019
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Collaborations and top research areas from the last five years
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Small molecule therapeutics to target toxic tau-signalling pathways
Ariawan, D. (Primary Chief Investigator), Van Eersel, J. (Associate Investigator) & Ittner, L. (Associate Investigator)
15/05/25 → 14/05/26
Project: Research
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DARF 2024: On Demand gene therapy for dementia
Przybyla, M. (Primary Chief Investigator), Van Eersel, J. (Associate Investigator), Ariawan, D. (Associate Investigator) & Ittner, L. (Associate Investigator)
1/04/25 → 1/04/28
Project: Research
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DEV 24: A novel protein-protein interaction inhibitor to treat Alzheimer’s disease
Ittner, L. (Primary Chief Investigator), Meier, R. (Chief Investigator), Van Eersel, J. (Chief Investigator), Tietz, O. (Chief Investigator), Ariawan, D. (Chief Investigator), Bi, M. (Chief Investigator) & Goozee, K. (Associate Investigator)
1/01/25 → 31/12/27
Project: Research
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Advancing cell-targeted and immune-resistant gene therapy for frontotemporal dementia and motor neuron disease
Ke, Y. (Primary Chief Investigator), van Hummel, A. (Chief Investigator), Ariawan, D. (Chief Investigator), Ittner, L. (Chief Investigator) & Rowe, D. (Chief Investigator)
1/10/24 → 30/09/27
Project: Research
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IDEAS 23: New biological drugs to treat Alzheimer's disease
Ittner, L. (Primary Chief Investigator), Ariawan, D. (Chief Investigator), Llorente, B. (Chief Investigator) & Tietz, O. (Associate Investigator)
1/01/24 → 31/12/27
Project: Research
Research Outputs
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Structural insights into the nuclear import of Gallid alphaherpesvirus 1 large tegument protein
Nath, B. K., Swarbrick, C. M. D., Blades, R., Ariawan, D., Tietz, O., Alvisi, G., Forwood, J. K. & Sarker, S., Feb 2026, In: MicrobiologyOpen. 15, 1, p. 1-12 12 p., e70216.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Structural insights into the nuclear import of ovine gammaherpesvirus 2 ORF73 LANA homologue
Nath, B. K., Schwab, R. H. M., Swarbrick, C. M. D., Pavan, S., Rahman, N., McSharry, B. P., Raidal, S. R., Ariawan, D., Tietz, O., Das, S., Alvisi, G. & Forwood, J. K., 17 Apr 2026, In: Journal of General Virology. 107, 4, p. 1-17 17 p., 002250.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Engineered cyclotide blocks neuronal excitotoxicity
Ariawan, D., van der Hoven, J., Morey, N., Pushpitha, K., Genoud, S., Stefen, H., Veltman, S., Przybyla, M., Deng, Y., Fath, T., Tietz, O., van Eersel, J. & Ittner, L. M., 13 Mar 2025, In: Journal of Medicinal Chemistry. 68, 5, p. 5211-5221 11 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Citations (Scopus) -
Nuclear trafficking of Anelloviridae capsid protein ORF1 reflects modular evolution of subcellular targeting signals
Petersen, G. F., Pavan, S., Ariawan, D., Tietz, O., Nematollahzadeh, S., Sarker, S., Forwood, J. K. & Alvisi, G., 16 Sept 2025, In: Virus Evolution. 11, 1, p. 1-14 14 p., veaf069.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Link opens in a new tab Citations (Scopus)10 Downloads (Pure) -
Optimizing intranasal delivery of peptides for targeted brain drug delivery in transgenic mouse models of Alzheimer’s disease
Wong, C. Y. J., Blank, J., van der Hoven, J., Ariawan, D., Reeman, J., Lam, H., Leslie, M., Ittner, L., Tietz, O., Ong, H. X. & Traini, D., May 2025, RDD Europe 2025: Bringing the respiratory world together. Dably, R. N., Peart, J., Traini, D., Young, P. M. & Suman, J. D. (eds.). Portugal: RDD Online, p. 156-160 5 p.Research output: Chapter in Book/Report/Conference proceeding › Conference proceeding contribution › peer-review