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Research Outputs 1990 2019

2019

Neurotrophin gene augmentation by electrotransfer to improve cochlear implant hearing outcomes

Pinyon, J. L., von Jonquieres, G., Crawford, E. N., Duxbury, M., Al Abed, A., Lovell, N. H., Klugmann, M., Wise, A. K., Fallon, J. B., Shepherd, R. K., Birman, C. S., Lai, W., McAlpine, D., McMahon, C., Carter, P. M., Enke, Y. L., Patrick, J. F., Schilder, A. G. M., Marie, C., Scherman, D. & 1 othersHousley, G. D., 1 Sep 2019, In : Hearing Research. 380, p. 137-149 13 p.

Research output: Contribution to journalReview articleResearchpeer-review

Cochlear Implants
Nerve Growth Factors
Hearing
Spiral Ganglion
Genes
2018

A common periodic representation of interaural time differences in mammalian cortex

Salminen, N. H., Jones, S. J., Christianson, G. B., Marquardt, T. & McAlpine, D., 15 Feb 2018, In : NeuroImage. 167, p. 95-103 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Hearing
Mammals
Auditory Cortex
Aptitude
Cues

Hearing: representing the aural wallpaper

McAlpine, D., 21 May 2018, In : Current Biology. 28, 10, p. R610-R612 3 p.

Research output: Contribution to journalShort surveyResearchpeer-review

home furnishings
Audition
hearing
Hearing
Ear

Hidden hearing loss selectively impairs neural adaptation to loud sound environments

Bakay, W. M. H., Anderson, L. A., Garcia-Lazaro, J. A., McAlpine, D. & Schaette, R., 16 Oct 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 4298.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
auditory defects
Audition
Hearing Loss
Acoustic waves
Noise

Increased spontaneous firing rates in auditory midbrain following noise exposure are specifically abolished by a Kv3 channel modulator

Anderson, L. A., Hesse, L. L., Pilati, N., Bakay, W. M. H., Alvaro, G., Large, C. H., McAlpine, D., Schaette, R. & Linden, J. F., Aug 2018, In : Hearing Research. 365, p. 77-89 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesencephalon
Noise
Inferior Colliculi
Hyperacusis
Pathology

Towards a new assessment battery: hearing, cognition, and emotional health

Strutt, P., Barnier, A., McAlpine, D., Edwards, B. & McMahon, C., 2018.

Research output: Contribution to conferenceAbstractResearch

Hearing Loss
Cognition
Hearing
Health
Dementia
2017

Differences in the temporal course of interaural time difference sensitivity between acoustic and electric hearing in amplitude modulated stimuli

Hu, H., Ewert, S. D., McAlpine, D. & Dietz, M., Mar 2017, In : Journal of the Acoustical Society of America. 141, 3, p. 1862-1873 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Acoustics
Hearing
Cochlear Implants
Cues
Electrodes

Influence of envelope waveform on ITD sensitivity of neurons in the auditory midbrain

Greenberg, D., Monaghan, J. J. M., Dietz, M., Marquardt, T. & McAlpine, D., 17 Oct 2017, In : Journal of Neurophysiology. 118, 4, p. 2358-2370 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesencephalon
Neurons
Cues
Electrophysiology
Urethane

Introducing the Australian Hearing Hub

McAlpine, D., McMahon, C., Dillon, H., Leigh, G., Hungerford, J., Patrick, J., Cowan, R. & Dodd, L., Jan 2017, In : Trends in hearing. 21, p. 1-3 3 p.

Research output: Contribution to journalEditorialResearch

Open Access
File
Hearing
Health Communication
Research
2016

Cochlear implant design considerations

Wilson, B. S., Dorman, M. F., Gifford, R. H. & McAlpine, D., 1 Jan 2016, Pediatric Cochlear Implantation: Learning and the Brain. Young, N. M. & Kirk, K. I. (eds.). New York ; Heidelberg : Springer, Springer Nature, p. 3-23 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Cochlear Implants
Perceptual Distortion
Cochlea
Acoustics
Electrodes

Meta-adaptation in the auditory midbrain under cortical influence

Robinson, B. L., Harper, N. S. & McAlpine, D., 24 Nov 2016, In : Nature Communications. 7, p. 1-8 8 p., 13442.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Mesencephalon
Neurons
Acoustic intensity
neurons
Auditory Cortex
Open Access
File
Ear
Phase Transition
Noise
Electroencephalography
Brain

Non-monotonic relation between noise exposure severity and neuronal hyperactivity in the auditory midbrain

Hesse, L. L., Bakay, W., Ong, H. C., Anderson, L., Ashmore, J., McAlpine, D., Linden, J. & Schaette, R., 25 Aug 2016, In : Frontiers in Neurology. 7, p. 1-13 13 p., 133.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Mesencephalon
Hearing Loss
Noise
Tinnitus
Cochlear Nerve

Objective measures of neural processing of interaural time differences

McAlpine, D., Haywood, N., Undurraga, J. & Marquardt, T., 2016, In : Advances in Experimental Medicine and Biology. 894, p. 197-205 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Phase modulation
Ear
Processing
Acoustic waves
Neurons

Sensitivity to Interaural Time Differences Conveyed in the Stimulus Envelope: Estimating Inputs of Binaural Neurons Through the Temporal Analysis of Spike Trains

Dietz, M., Wang, L., Greenberg, D. & McAlpine, D., 1 Aug 2016, In : JARO - Journal of the Association for Research in Otolaryngology. 17, 4, p. 313-330 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Neurons
Ear
Sound Localization
Inferior Colliculi
Cochlear Implants
2015

A Bilateral hearing assistance system and a method of fitting a bilateral hearing assistance system

Laudanski, J., Undurraga, J. A., Haywood, N., Marquardt, T. & McAlpine, D., 2015, IPC No. H04R 25/00, Patent No. EP2919483, Priority date 11 Mar 2014, Priority No. 14158959

Research output: PatentResearch

Audition
Cochlear implants
Processing
Speech intelligibility
Patents and inventions
Open Access
File

Advancing binaural cochlear implant technology

Dietz, M. & McAlpine, D., 30 Dec 2015, In : Trends in hearing. 19, p. 1-4 4 p.

Research output: Contribution to journalEditorialResearchpeer-review

Open Access
File

Phosphoinositide modulation of heteromeric Kv1 channels adjusts output of spiral ganglion neurons from hearing mice

Smith, K. E., Browne, L., Selwood, D. L., McAlpine, D. & Jagger, D. J., 12 Aug 2015, In : Journal of Neuroscience. 35, 32, p. 11221-11232 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Spiral Ganglion
Phosphatidylinositols
Hearing
Kv1.2 Potassium Channel
Neurons

Reducing current spread by use of a novel pulse shape for electrical stimulation of the auditory nerve

Ballestero, J., Recugnat, M., Laudanski, J., Smith, K. E., Jagger, D. J., Gnansia, D. & McAlpine, D., 30 Dec 2015, In : Trends in hearing. 19, p. 1-12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Sensitivity to envelope interaural time differences at high modulation rates

Monaghan, J. J. M., Bleeck, S. & McAlpine, D., 2015, In : Trends in hearing. 19, p. 1-14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014

A model that predicts the binaural advantage to speech intelligibility from the mixed target and interferer signals

Cosentino, S., Marquardt, T., McAlpine, D., Culling, J. F. & Falk, T. H., 2014, In : Journal of the Acoustical Society of America. 135, 2, p. 796-807 12 p.

Research output: Contribution to journalArticleResearchpeer-review

intelligibility
ear
cancellation
frequency modulation
recording

"Change deafness" arising from inter-feature masking within a single auditory object

Barascud, N., Griffiths, T. D., McAlpine, D. & Chait, M., 2014, In : Journal of cognitive neuroscience. 26, 3, p. 514-528 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Magnetoencephalography
deafness
Deafness
Psychophysics
Aptitude

Cochlear implant filterbank design and optimization: A simulation study

Cosentino, S., Falk, T. H., McAlpine, D. & Marquardt, T., 2014, In : IEEE Transactions on Audio, Speech and Language Processing. 22, 2, p. 347-353 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cochlear implants
Cochlear Implants
filters
frequency analysis
simulation

Emphasis of spatial cues in the temporal fine structure during the rising segments of amplitude-modulated sounds II: Single-neuron recordings

Dietz, M., Marquardt, T., Stange, A., Pecka, M., Grothe, B. & McAlpine, D., 2014, In : Journal of Neurophysiology. 111, 10, p. 1973-1985 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Cues
Inferior Colliculi
Neurons
Gerbillinae
Guinea Pigs

Selective adaptation to "Oddball" sounds by the human auditory system

Simpson, A. J. R., Harper, N. S., Reiss, J. D. & McAlpine, D., 2014, In : Journal of Neuroscience. 34, 5, p. 1963-1969 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Auditory Perception
Mammals
Discrimination (Psychology)

Subthreshold resonance properties contribute to the efficient coding of auditory spatial cues

Remme, M. W. H., Donato, R., Mikiel-Hunter, J., Ballestero, J. A., Foster, S., Rinzel, J. & McAlpine, D., 3 Jun 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 22, p. E2339-E2348 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Cues
Neurons
Extremities
Electric Impedance
Brain Stem

The neural code for auditory space depends on sound frequency and head size in an optimal manner

Harper, N. S., Scott, B. H., Semple, M. N. & McAlpine, D., 5 Nov 2014, In : PLoS ONE. 9, 11, p. 1-10 10 p., e108154.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Head
Acoustic waves
Cues
Dipodomys
Neurophysiology
2013

Emphasis of spatial cues in the temporal fine structure during the rising segments of amplitude-modulated sounds

Dietz, M., Marquardt, T., Salminen, N. H. & McAlpine, D., 10 Sep 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 37, p. 15151-15156 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Cues
Aptitude
Brain
Psychoacoustics
Magnetoencephalography

Evaluation of the acoustic coordinated reset (CR ®) neuromodulation therapy for tinnitus: study protocol for a double-blind randomized placebo-controlled trial

Hoare, D. J., Pierzycki, R. H., Thomas, H., McAlpine, D. & Hall, D. A., 10 Jul 2013, In : Trials. 14, p. 1-8 8 p., 207.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Tinnitus
Acoustics
Randomized Controlled Trials
Placebos
Therapeutics

Predicting the bilateral advantage in cochlear implantees using a non-intrusive speech intelligibility measure

Cosentino, S., Falk, T. H. & McAlpine, D., 2013, Proceedings of the Annual Conference of the International Speech Communication Association. Bimbot, F., Cerisara, C., Fougeron, C., Gravier, G., Lamel, L., Pellegrino, F. & Perrier, P. (eds.). Baixas: International Speech Communication Association (ISCA), p. 2277-2281 5 p. (Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH).

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

Speech Intelligibility
Cochlear implants
Speech intelligibility
Implant
Frequency Estimation

The influence of the envelope waveform on binaural tuning of neurons in the inferior colliculus and its relation to binaural perception

Dietz, M., Marquardt, T., Greenberg, D. & McAlpine, D., 2013, Basic Aspects of Hearing: Physiology and Perception. Moore, B. C. J., Patterson, R. D., Winter, I. M., Carlyon, R. P. & Gockel, H. E. (eds.). New York: Springer, Springer Nature, Vol. 787. p. 223-230 8 p. (Advances in Experimental Medicine and Biology; vol. 787).

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

Psychoacoustics
Inferior Colliculi
Neurons
Tuning
Guinea Pigs

Tuning of human modulation filters is carrier-frequency dependent

Simpson, A. J. R., Reiss, J. D. & McAlpine, D., 29 Aug 2013, In : PLoS ONE. 8, 8, p. 1-9 9 p., e73590.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Tuning
Modulation
Noise
Acoustic waves
methodology
2012

Adaptive coding is constrained to midline locations in a spatial listening task

Maier, J. K., Hehrmann, P., Harper, N. S., Klump, G. M., Pressnitzer, D. & McAlpine, D., 1 Oct 2012, In : Journal of Neurophysiology. 108, 7, p. 1856-1868 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Mesencephalon
Sound Localization
Acoustics
Cues
Guinea Pigs

Cortical responses to changes in acoustic regularity are differentially modulated by attentional load

Chait, M., Ruff, C. C., Griffiths, T. D. & McAlpine, D., 16 Jan 2012, In : NeuroImage. 59, 2, p. 1932-1941 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Acoustics
Auditory Cortex
Brain

Towards objective measures of speech intelligibility for Cochlear Implant users in reverberant environments

Cosentino, S., Marquardt, T., McAlpine, D. & Falk, T. H., 2012, 2012 11th International Conference on Information Science, Signal Processing and their Applications, ISSPA 2012. Piscataway, NJ: Institute of Electrical and Electronics Engineers (IEEE), p. 666-671 6 p. 6310637

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

Cochlear implants
Speech intelligibility
Reverberation
Vocoders
Fast Fourier transforms
2011

Developing a neuro-centric perspective to cochlear implantation

McAlpine, D., May 2011, In : Cochlear implants international. 12, Suppl 1, p. S40-S43 4 p.

Research output: Contribution to journalConference paperResearchpeer-review

Tinnitus with a normal audiogram: Physiological evidence for hidden hearing loss and computational model

Schaette, R. & McAlpine, D., 21 Sep 2011, In : Journal of Neuroscience. 31, 38, p. 13452-13457 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Tinnitus
Hearing Loss
Cochlea
Cochlear Nerve
Brain Stem Auditory Evoked Potentials
2010

Adaptive coding for auditory spatial cues

Hehrmann, P., Maier, J. K., Harper, N. S., McAlpine, D. & Sahani, M., 2010, The Neurophysiological bases of auditory perception. Lopez-Poveda, E. A., Palmer, A. R. & Meddis, R. (eds.). New York: Springer, Springer Nature, p. 357-366 10 p.

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review

Inferior Colliculi
Cues
Neurons
Statistical Distributions
Sound Localization

Context effects in the discriminability of spatial cues

Maier, J. K., McAlpine, D., Klump, G. M. & Pressnitzer, D., Jun 2010, In : JARO - Journal of the Association for Research in Otolaryngology. 11, 2, p. 319-328 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Cues
Aptitude
Noise

Mechanisms of sound localization in mammals

Grothe, B., Pecka, M. & McAlpine, D., Jul 2010, In : Physiological Reviews. 90, 3, p. 983-1012 30 p.

Research output: Contribution to journalReview articleResearchpeer-review

Sound Localization
Hearing
Mammals
Cues
Basilar Membrane

Physiological correlates of the precedence effect and binaural masking level differences

Litovsky, R. Y. & McAlpine, D., 2010, The Oxford Handbook of Auditory Science: the auditory brain. Palmer, A. R. & Rees, A. (eds.). New York: Oxford University Press, p. 333-358 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Aptitude
Psychophysics
Sound Localization
Electrophysiology
Brain
2009

Gain control mechanisms in the auditory pathway

Robinson, B. L. & McAlpine, D., Aug 2009, In : Current Opinion in Neurobiology. 19, 4, p. 402-407 6 p.

Research output: Contribution to journalReview articleResearchpeer-review

Auditory Pathways
Tigers
Acoustics
Hearing

Hierarchical processing of interaural time differences in the human brain

McAlpine, D., 2009, In : Journal of Physiological Sciences. 59, Supplement 1, p. 31-31 1 p.

Research output: Contribution to journalMeeting abstractResearchpeer-review

How General Are Neural Codes in Sensory Systems?

McAlpine, D. & Palmer, A. R., 1 May 2009, 23 Problems in Systems Neuroscience. van Hemmen, J. L. & Sejnowski, T. J. (eds.). Oxford; New York: Oxford University Press, p. 283-302 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Central Nervous System
Brain

Masking with interaurally "double-delayed" stimuli: The range of internal delays in the human brain

Marquardt, T. & McAlpine, D., 2009, In : Journal of the Acoustical Society of America. 126, 6, p. EL177-EL182 6 p.

Research output: Contribution to journalArticleResearchpeer-review

masking
stimuli
mammals
brain
bandwidth

The synaptic representation of sound source location in auditory cortex

Chadderton, P., Agapiou, J. P., McAlpine, D. & Margrie, T. W., 11 Nov 2009, In : Journal of Neuroscience. 29, 45, p. 14127-14135 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Auditory Cortex
Excitatory Postsynaptic Potentials
Pyramidal Cells
Acoustic Stimulation
Patch-Clamp Techniques
2008

Low-frequency envelope sensitivity produces asymmetric binaural tuning curves

Agapiou, J. P. & McAlpine, D., Oct 2008, In : Journal of Neurophysiology. 100, 4, p. 2381-2396 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Inferior Colliculi
Mesencephalon
Neurons
Cues
Space Perception

Rapid neural adaptation to sound level statistics

Dean, I., Robinson, B. L., Harper, N. S. & McAlpine, D., 18 Jun 2008, In : Journal of Neuroscience. 28, 25, p. 6430-6438 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Neurons
Mesencephalon
Population

Responses to interaural time delay in human cortex

Von Kriegstein, K., Griffiths, T. D., Thompson, S. K. & McAlpine, D., Nov 2008, In : Journal of Neurophysiology. 100, 5, p. 2712-2718 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Brain
Ear
Inferior Colliculi
Human Activities
Neuroimaging