Deborah Schofield

Professor

  • Director, Centre for Economic Impacts of Genomic Medicine & Professor and Chair of Health Economics, Department of Economics
1994 …2022
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Research Output 1994 2019

2019

Does genomic sequencing early in the diagnostic trajectory make a difference? A follow-up study of clinical outcomes and cost-effectiveness

Stark, Z., Schofield, D., Martyn, M., Rynehart, L., Shrestha, R., Alam, K., Lunke, S., Tan, T. Y., Gaff, C. L. & White, S. M., 2019, In : Genetics in Medicine. 21, 1, p. 173-180 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Exome
Cost-Benefit Analysis
Quality-Adjusted Life Years
Costs and Cost Analysis
Disclosure

Economic costs of informal care for people with chronic diseases in the community: Lost income, extra welfare payments, and reduced taxes in Australia in 2015–2030

Schofield, D., Shrestha, R. N., Zeppel, M. J. B., Cunich, M. M., Tanton, R., Veerman, J. L., Kelly, S. J. & Passey, M. E., 2019, In : Health and Social Care in the Community. 27, 2, p. 493-501 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Taxes
Caregivers
taxes
Patient Care
Chronic Disease

Productivity costs of cardiovascular disease mortality across disease types and socioeconomic groups

Carter, H. E., Schofield, D. & Shrestha, R., 1 Feb 2019, In : Open Heart. 6, 1, 8 p., e000939.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cost of Illness
Cardiovascular Diseases
Mortality
Premature Mortality
Economics
2018

A Brief, global history of microsimulation models in health: past applications, lessons learned and future directions

Schofield, D. J., Zeppel, M. J. B., Tan, O., Lymer, S., Cunich, M. M. & Shrestha, R. N., 1 Mar 2018, In : International Journal of Microsimulation. 11, 1, p. 97-142 46 p.

Research output: Contribution to journalArticleResearchpeer-review

Microsimulation
Health
Model
History
Model Error

Application of next-generation sequencing to improve cancer management: A review of the clinical effectiveness and cost-effectiveness

Tan, O., Shrestha, R., Cunich, M. & Schofield, D. J., Mar 2018, In : Clinical Genetics. 93, 3, p. 533-544 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Cost-Benefit Analysis
Neoplasms
Mutation
Costs and Cost Analysis
MEDLINE

Care&WorkMOD: An Australian microsimulation model projecting the economic impacts of early retirement in informal carers

Shrestha, R., Schofield, D., Zeppel, M. J. B., Cunich, M., Tanton, R., Kelly, S. J., Veerman, L. & Passey, M. E., 2018, In : International Journal of Microsimulation. 11, 3, p. 78-99 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Microsimulation
Economics
Chronic Disease
Aging of materials
Personnel

Economic evaluation of genomic sequencing in the paediatric population: a critical review

Alam, K. & Schofield, D., 2018, In : European Journal of Human Genetics. 26, 9, p. 1241-1247 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cost-Benefit Analysis
Pediatrics
Population
Health Policy
Checklist

Effectiveness of a new model of primary care management on knee pain and function in patients with knee osteoarthritis: Protocol for the PARTNER STUDY

PARTNER Study Team, 30 Apr 2018, In : BMC Musculoskeletal Disorders. 19, p. 1-16 16 p., 132.

Research output: Contribution to journalArticleResearch

Open Access
File
Knee Osteoarthritis
General Practitioners
Primary Health Care
Knee
Pain

Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness

Palmer, E. E., Schofield, D., Shrestha, R., Kandula, T., Macintosh, R., Lawson, J. A., Andrews, I., Sampaio, H., Johnson, A. M., Farrar, M. A., Cardamone, M., Mowat, D., Elakis, G., Lo, W., Zhu, Y., Ying, K., Morris, P., Tao, J., Dias, K-R., Buckley, M. & 6 othersDinger, M. E., Cowley, M. J., Roscioli, T., Kirk, E. P., Bye, A. & Sachdev, R. K., Mar 2018, In : Molecular genetics & genomic medicine. 6, 2, p. 186-199 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Exome
Brain Diseases
Cost-Benefit Analysis
Costs and Cost Analysis
Critical Pathways

Optimising primary care management of knee osteoarthritis (partner): protocol for a randomised controlled trial

Hunter, D. J., Hinman, R. S., Bowden, J. L., Egerton, T., Briggs, A. M., Bunker, S. J., Forbes, A. B., French, S. D., Kasza, J., Pirotta, M., Schofield, D. J., Zwar, N. A., Bennell, K. L. & PARTNER Study Team, Apr 2018, In : Osteoarthritis and Cartilage. 26, Supplement 1, p. S270-S271 2 p.

Research output: Contribution to journalMeeting abstractResearch

Knee Osteoarthritis
Primary Health Care
Randomized Controlled Trials
Osteoarthritis
General Practitioners

Protocol for the Lactoferrin Infant Feeding Trial (LIFT): A randomised trial of adding lactoferrin to the feeds of very-low birthweight babies prior to hospital discharge

LIFT Collaborative Study Group, Martin, A., Ghadge, A., Manzoni, P., Lui, K., Brown, R. & Tarnow-Mordi, W., 1 Oct 2018, In : BMJ Open. 8, 10, 8 p., e023044.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Lactoferrin
Necrotizing Enterocolitis
Brain Injuries
Survival
Length of Stay

Psychological distress increases the risk of falling into poverty amongst older Australians: the overlooked costs-of-illness

Callander, E. J. & Schofield, D. J., 17 Apr 2018, In : BMC Psychology. 6, p. 1-9 9 p., 16.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Cost of Illness
Poverty
Psychology
Marital Status
Mental Health
Ankylosing Spondylitis
Economics
Pain
Income Tax
Insurance Benefits

The long-term economic impacts of arthritis through lost productive life years: results from an Australian microsimulation model

Schofield, D., Cunich, M., Shrestha, R. N., Tanton, R., Veerman, L., Kelly, S. & Passey, M. E., 24 May 2018, In : BMC Public Health. 18, 1, p. 1-10 10 p., 654.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Arthritis
Economics
Costs and Cost Analysis
Health
Income Tax

The Population cost-effectiveness of Weight Watchers with general practitioner referral compared with standard care

Lymer, S., Schofield, D., Cunich, M., Lee, C. M. Y., Fuller, N., Caterson, I. & Colagiuri, S., 1 Aug 2018, In : Obesity. 26, 8, p. 1261-1269 9 p.

Research output: Contribution to journalArticleResearchpeer-review

General Practitioners
Cost-Benefit Analysis
Referral and Consultation
Obesity
Weights and Measures

Whole-exome sequencing reanalysis at 12 months boosts diagnosis and is cost-effective when applied early in Mendelian disorders

Ewans, L. J., Schofield, D., Shrestha, R., Zhu, Y., Gayevskiy, V., Ying, K., Walsh, C., Lee, E., Kirk, E. P., Colley, A., Ellaway, C., Turner, A., Mowat, D., Worgan, L., Freckmann, M-L., Lipke, M., Sachdev, R., Miller, D., Field, M., Dinger, M. E. & 3 othersBuckley, M. F., Cowley, M. J. & Roscioli, T., 1 Dec 2018, In : Genetics in medicine : official journal of the American College of Medical Genetics. 20, 12, p. 1564-1574 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Exome
Costs and Cost Analysis
Intellectual Disability
Cost-Benefit Analysis
Technology
2017

A Closing window of opportunity—when does multidimensional poverty become chronic? A longitudinal study of Australians

Callander, E. J. & Schofield, D. J., 2017, New dimensions in community well-being. Kraeger, P., Cloutier, S. & Talmage, C. (eds.). Cham: Springer, Springer Nature, p. 115-128 14 p. (Community quality-of-life and well-being).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Longitudinal study
Poverty
Multidimensional poverty
Low income
Household income

Cost-effectiveness of massively parallel sequencing for diagnosis of paediatric muscle diseases

Schofield, D., Alam, K., Douglas, L., Shrestha, R., MacArthur, D. G., Davis, M., Laing, N. G., Clarke, N. F., Burns, J., Cooper, S. T., North, K. N., Sandaradura, S. A. & O’Grady, G. L., 2017, In : npj Genomic Medicine. 2, 1, p. 1-7 7 p., 4.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
High-Throughput Nucleotide Sequencing
Exome
Neuromuscular Diseases
Cost-Benefit Analysis
Pediatrics

Diagnostic impact and cost-effectiveness of whole-exome sequencing for ambulant children with suspected monogenic conditions

Tan, T. Y., Dillon, O. J., Stark, Z., Schofield, D., Alam, K., Shrestha, R., Chong, B., Phelan, D., Brett, G. R., Creed, E., Jarmolowicz, A., Yap, P., Walsh, M., Downie, L., Amor, D. J., Savarirayan, R., McGillivray, G., Yeung, A., Peters, H., Robertson, S. J. & 9 othersRobinson, A. J., Macciocca, I., Sadedin, S., Bell, K., Oshlack, A., Georgeson, P., Thorne, N., Gaff, C. & White, S. M., 1 Sep 2017, In : JAMA Pediatrics. 171, 9, p. 855-862 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Exome
Cost-Benefit Analysis
Referral and Consultation
Cost Savings
Insurance Pools

Health economic evaluation in rare disease genomics: an international perspective

Stark, Z., Schofield, D. & Gaff, C., 14 Sep 2017

Research output: Non-traditional research outputWeb publication/siteResearch

Open Access
Internationality
Rare Diseases
Genomics
Cost-Benefit Analysis
Exome

Impact of multidimensional poverty on the self-efficacy of older people: Results from an Australian longitudinal study

Callander, E. J. & Schofield, D. J., 1 Feb 2017, In : Geriatrics and Gerontology International. 17, 2, p. 308-314 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Self Efficacy
Poverty
self-efficacy
Longitudinal Studies
longitudinal study

Prioritising the application of genomic medicine

Doble, B., Schofield, D. J., Roscioli, T. & Mattick, J. S., 1 Dec 2017, In : npj Genomic Medicine. 2, 1, p. 1-6 6 p., 35.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Medicine
Penetrance
Genetic Association Studies
Genomics
Health

Prospective comparison of the cost-effectiveness of clinical whole-exome sequencing with that of usual care overwhelmingly supports early use and reimbursement

Stark, Z., Schofield, D., Alam, K., Wilson, W., Mupfeki, N., Macciocca, I., Shrestha, R., White, S. M. & Gaff, C., 1 Aug 2017, In : Genetics in Medicine. 19, 8, p. 867-874 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Exome
Cost-Benefit Analysis
Costs and Cost Analysis

The costs of diabetes among Australians aged 45-64 years from 2015 to 2030: projections of lost productive life years (PLYs), lost personal income, lost taxation revenue, extra welfare payments and lost gross domestic product from Health&WealthMOD2030

Schofield, D., Shrestha, R. N., Cunich, M. M., Passey, M. E., Veerman, L., Tanton, R. & Kelly, S. J., 1 Jan 2017, In : BMJ Open. 7, 1, 11 p., e013158.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Gross Domestic Product
Taxes
Costs and Cost Analysis
Health
Health Care Costs

The long-term productivity impacts of all cause premature mortality in Australia

Carter, H. E., Schofield, D. & Shrestha, R., 1 Apr 2017, In : Australian and New Zealand Journal of Public Health. 41, 2, p. 137-143 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Premature Mortality
Economics
Cause of Death
Costs and Cost Analysis
Cost of Illness

Working beyond the traditional retirement age: the influence of health on Australia’s older workers

Schofield, D. J., Callander, E. J., Kelly, S. J. & Shrestha, R. N., 27 May 2017, In : Journal of Aging and Social Policy. 29, 3, p. 235-244 10 p.

Research output: Contribution to journalArticleResearchpeer-review

retirement age
Retirement
worker
Health
health
2016

Arthritis and the risk of falling into poverty: A survival analysis using Australian data

Callander, E. J. & Schofield, D. J., 1 Jan 2016, In : Arthritis and Rheumatology. 68, 1, p. 255-262 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Poverty
Survival Analysis
Arthritis
Confidence Intervals
Longitudinal Studies

Counting the cost: the current and future burden of arthritis. Part 2. Economic costs

Schofield, D., Shrestha, R. & Cunich, M., May 2016, Sydney: Arthritis Australia. 36 p.

Research output: Book/ReportCommissioned reportResearch

Open Access
File
Arthritis
Economic cost
Burden
Costs
Labor force participation

Economic costs of chronic disease through lost productive life years (PLYs) among Australians aged 45–64 years from 2015 to 2030: results from a microsimulation model

Schofield, D., Shrestha, R. N., Cunich, M. M., Tanton, R., Veerman, L., Kelly, S. J. & Passey, M. E., 1 Sep 2016, In : BMJ Open. 6, 9, 9 p., e011151.

Research output: Contribution to journalArticleResearchpeer-review

Cost of Illness
Chronic Disease
Economics
Taxes
Caregivers

Higher education attainment does not improve the adult employment outcomes of adolescents with ill health

Callander, E. J., Schofield, D. & Shrestha, R., 2016, In : Journal of social inclusion. 7, 1, p. 49-58 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Education
Health
Sex Education
Poverty
Health Status

Keep on keeping on: Predicting who will be able to work until they are 70 years old

Schofield, D., Shrestha, R., Cunich, M. & Callander, E., May 2016, 19 p.

Research output: Book/ReportOther reportResearch

health
labor force participation
pension
labor force
human capital

NCDMod: A microsimulation model projecting chronic disease and risk factors for australian adults

Lymer, S., Schofield, D., Lee, C. M. Y. & Colagiuri, S., 2016, In : International Journal of Microsimulation. 9, 3, p. 103-139 37 p.

Research output: Contribution to journalArticleResearchpeer-review

Microsimulation
Chronic Disease
Risk Factors
Health
Obesity

Pathways into chronic multidimensional poverty amongst older people: a longitudinal study

Callander, E. J. & Schofield, D. J., 2016, In : BMC Geriatrics. 16, 1, 8 p., 62.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Poverty
Longitudinal Studies
Health
Education
Linear Models

The impact of poverty on self-efficacy: an Australian longitudinal study

Callander, E. J. & Schofield, D. J., 7 Jun 2016, In : Occupational Medicine. 66, 4, p. 320-325 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Self Efficacy
Poverty
Longitudinal Studies
Workplace
Emotions

The indirect costs of back problems (dorsopathies) in Australians aged 45 to 64 years from 2015 to 2030: results from a microsimulation model, Health&WealthMOD2030

Schofield, D., Cunich, M. M., Shrestha, R. N., Tanton, R., Veerman, L., Kelly, S. J. & Passey, M. E., 10 Aug 2016, In : Pain. 157, 12, p. 2816-2825 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Gross Domestic Product
Taxes
Costs and Cost Analysis
Health
Income Tax

The potential for poverty to lower the self-efficacy of adults with asthma: An Australian longitudinal study

Callander, E. J. & Schofield, D. J., 2016, In : Allergy, Asthma and Immunology Research. 8, 2, p. 141-145 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Self Efficacy
Poverty
Longitudinal Studies
Asthma
Emotions

The productivity costs of premature mortality due to cancer in Australia: evidence from a microsimulation model

Carter, H. E., Schofield, D. J. & Shrestha, R., 1 Dec 2016, In : PLoS ONE. 11, 12, e0167521.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Premature Mortality
Productivity
Costs and Cost Analysis
neoplasms
Costs

The promise of personalised medicine

Doble, B., Schofield, D. J., Roscioli, T. & Mattick, J. S., 30 Jan 2016, In : The Lancet. 387, 10017, p. 433-434 2 p.

Research output: Contribution to journalLetterResearchpeer-review

The risk of falling into poverty after developing heart disease: a survival analysis

Callander, E. J. & Schofield, D. J., 15 Jul 2016, In : BMC Public Health. 16, 1, 10 p., 570.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Poverty
Survival Analysis
Heart Diseases
Ownership
Marital Status

Type 2 diabetes mellitus and the risk of falling into poverty: an observational study

Callander, E. J. & Schofield, D. J., 1 Sep 2016, In : Diabetes/Metabolism Research and Reviews. 32, 6, p. 581-588 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Poverty
Type 2 Diabetes Mellitus
Observational Studies
Longitudinal Studies
Survival Analysis
2015

Back problems, comorbidities, and their association with wealth

Schofield, D. J., Callander, E. J., Shrestha, R. N., Passey, M. E., Kelly, S. J. & Percival, R., 1 Jan 2015, In : Spine Journal. 15, 1, p. 34-41 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Comorbidity
Health
Confidence Intervals
Linear Models
Logistic Models

CMT in Australia: A survey of cost-utility, wellbeing and management

Denton, S., Schofield, D., Poynten, J. & Burns, J., 7 Jul 2015, In : Journal of the Peripheral Nervous System. 20, 2, p. 127-128 2 p.

Research output: Contribution to journalMeeting abstractResearch

Costs and Cost Analysis
Muscular Dystrophies
Health
Nervous System Diseases
Australian Capital Territory

Depression prevention, labour force participation and income of older working aged Australians: A microsimulation economic analysis

Veerman, J. L., Shrestha, R. N., Mihalopoulos, C., Passey, M. E., Kelly, S. J., Tanton, R., Callander, E. J. & Schofield, D. J., 6 May 2015, In : Australian and New Zealand Journal of Psychiatry. 49, 5, p. 430-436 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Economics
Depression
Taxes
Economic Recession
Psychology

Effect of asthma on falling into poverty: the overlooked costs of illness

Callander, E. J. & Schofield, D. J., 1 May 2015, In : Annals of Allergy, Asthma and Immunology. 114, 5, p. 374-378 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Cost of Illness
Poverty
Asthma
Confidence Intervals
Costs and Cost Analysis
Iron-Deficiency Anemias
Language
Iron
Cross-Sectional Studies
Economics

Labour force participation and the influence of having arthritis on financial status

Schofield, D. J., Callander, E. J., Shrestha, R. N., Percival, R., Kelly, S. J. & Passey, M. E., 26 Jul 2015, In : Rheumatology International. 35, 7, p. 1175-1181 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Arthritis
Poverty
Health
Psychological Stress
Caregivers

Lost productive life years caused by chronic conditions in Australians aged 45–64 years, 2010–2030

Schofield, D. J., Shrestha, R. N., Cunich, M., Tanton, R., Kelly, S., Passey, M. E. & Veerman, L. J., 21 Sep 2015, In : Medical Journal of Australia. 203, 6, p. 260.e1-260.e6 6 p., 260.

Research output: Contribution to journalArticleResearchpeer-review

Gross Domestic Product
Population Growth
Chronic Disease
Premature Obstetric Labor
Health

Multidimensional poverty and health status as a predictor of chronic income poverty

Callander, E. J. & Schofield, D. J., 1 Dec 2015, In : Health Economics (United Kingdom). 24, 12, p. 1638-1643 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Poverty
Health Status
Health Services Needs and Demand
Public Policy
Health Education

Multiple chronic health conditions and their link with wealth assets

Schofield, D. J., Callander, E. J., Shrestha, R. N., Passey, M. E., Kelly, S. J. & Percival, R., 1 Apr 2015, In : European Journal of Public Health. 25, 2, p. 285-289 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Health
Multiple Chronic Conditions
Economics
Morbidity
Research