Projects per year
Personal profile
Biography
Dr. Devaraj Basavarajappa is a Senior Research Fellow at the Macquarie Medical School, Faculty of Medicine, Health and Human Sciences. His research focuses on uncovering the mechanisms of neurodegeneration and neuroinflammation in optic neuropathies and trans-synaptic neurodegeneration within the brain, using a range of degenerative animal models. His primary aim is to redefine our understanding of neurodegenerative diseases affecting the retina and the visual pathway, with a focus on cellular signaling, cell death pathways, microRNAs, and neuroinflammatory processes.
He received his PhD from the Council of Scientific and Industrial Research (CSIR) laboratory in India. He brings extensive research experience in vision neuroscience, inflammation, and inflammatory resolution, gained from his work at the Dean McGee Eye Institute in the USA and the Nobel Prize-winning laboratory at the Karolinska Institute in Sweden.
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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The next generation of medicine-Gene therapy for glaucoma
Basavarajappa, D., Chitranshi, N. & Vishwanath, D.
1/01/22 → 31/12/22
Project: Research
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Retinal Changes as diagnostic marker to identify Early Alzheimer’s Disease
Gupta, V., You, Y., Schulz, A., Basavarajappa, D., Graham, S. L. & Gupta, V. B.
1/12/19 → 31/12/21
Project: Other
Research Outputs
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Brain-derived neurotrophic factor Val66Met is associated with variation in cortical structure in healthy aging subjects
Shen, T., Sheriff, S., You, Y., Jiang, J., Schulz, A., Francis, H., Mirzaei, M., Saks, D., Palanivel, V., Basavarajappa, D., Chitranshi, N., Gupta, V., Wen, W., Sachdev, P. S., Jia, H., Sun, X., Graham, S. L. & Gupta, V. K., 1 Oct 2024, In: Aging and Disease. 15, 5, p. 2315-2327 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Downloads (Pure) -
Elevated CD11b-positive microglia and CD3-positive cells in glaucoma: insights from post-mortem retinal analysis
Salkar, A. A., Vander Wall, R., Basavarajappa, D., Chitranshi, N., Gupta, V., You, Y. & Graham, S. L., 17 Jun 2024, In: Investigative Ophthalmology and Visual Science. 65, 7, p. 6768 1 p.Research output: Contribution to journal › Meeting abstract
File13 Downloads (Pure) -
Glial cell activation and immune responses in glaucoma: a systematic review of human postmortem studies of the retina and optic nerve
Salkar, A., Vander Wall, R., Basavarajappa, D., Chitranshi, N., Parilla, G. E., Mirzaei, M., Yan, P., Graham, S. & You, Y., 1 Oct 2024, In: Aging and Disease. 15, 5, p. 2069-2083 15 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile18 Downloads (Pure) -
Mechanisms of transsynaptic degeneration in the aging brain
Wall, R. V., Basavarajappa, D., Klistorner, A., Graham, S. & You, Y., 1 Oct 2024, In: Aging and Disease. 15, 5, p. 2149-2167 19 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile31 Downloads (Pure) -
Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model
Palanivel, V., Gupta, V., Chitranshi, N., Tietz, O., Wall, R. V., Blades, R., Thananthirige, K. P. M., Salkar, A., Shen, C., Mirzaei, M., Gupta, V., Graham, S. L. & Basavarajappa, D., 7 Aug 2024, In: PNAS Nexus. 3, 8, p. 1-15 15 p., pgae299.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Downloads (Pure)