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Biography
Dr. Devaraj Basavarajappa is a Senior Research Fellow at the Macquarie Medical School, Faculty of Medicine, Health and Human Sciences. His research focuses on uncovering the mechanisms of neurodegeneration and neuroinflammation in optic neuropathies and trans-synaptic neurodegeneration within the brain, using a range of degenerative animal models. His primary aim is to redefine our understanding of neurodegenerative diseases affecting the retina and the visual pathway, with a focus on cellular signaling, cell death pathways, microRNAs, and neuroinflammatory processes.
He received his PhD from the Council of Scientific and Industrial Research (CSIR) laboratory in India. He brings extensive research experience in vision neuroscience, inflammation, and inflammatory resolution, gained from his work at the Dean McGee Eye Institute in the USA and the Nobel Prize-winning laboratory at the Karolinska Institute in Sweden.
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Projects
- 3 Finished
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Novel Protective Effects of Neuropeptide Y for Glaucoma Retina
Basavarajappa, D. (Primary Chief Investigator), Chitranshi, N. (Chief Investigator), Raniga, A. (Chief Investigator), Viswanathan, D. (Chief Investigator), Gupta, V. (Co-Investigator) & Graham, S. L. (Co-Investigator)
1/01/25 → 30/06/26
Project: Research
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The next generation of medicine-Gene therapy for glaucoma
Basavarajappa, D. (Primary Chief Investigator), Chitranshi, N. (Chief Investigator) & Vishwanath, D. (Chief Investigator)
1/01/22 → 31/12/22
Project: Research
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Retinal Changes as diagnostic marker to identify Early Alzheimer’s Disease
Gupta, V. (Primary Chief Investigator), You, Y. (Chief Investigator), Schulz, A. (Chief Investigator), Basavarajappa, D. (Chief Investigator), Graham, S. L. (Associate Investigator) & Gupta, V. B. (Associate Investigator)
1/12/19 → 31/12/21
Project: Other
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Invisible threats of microplastics induced toxicity: oxidative and inflammatory pathways in the CNS and retina
Shenoy, A., Eva, T. A., Palanivel, V., Salkar, A., Gupta, V. B., Chitranshi, N., Graham, S. L., Gupta, V. & Basavarajappa, D., 2026, Brain Energy Metabolism in Alzheimers Disease: Part A. Academic Press Inc., p. 25-47 (International Review of Neurobiology; vol. 186).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Neuropeptide Y at the crossroads of neurodegeneration: mechanistic insights and emerging therapeutic strategies
Palanivel, V., Salkar, A., Shenoy, A., Eva, T. A., Perera, R., Chitranshi, N., Gupta, V., You, Y., Mirzaei, M., Graham, S. L., Gupta, V. & Basavarajappa, D., Feb 2026, In: Neuropeptides. 115, p. 1-14 14 p., 102583.Research output: Contribution to journal › Review article › peer-review
Open AccessFile5 Link opens in a new tab Citations (Scopus)5 Downloads (Pure) -
Retinal glial cells in glaucoma and age-related retinal diseases: Inflammatory responses, disease transitions, and translational perspectives
Salkar, A., Palanivel, V., Basavarajappa, D., Heng, B., Schulz, A., Gupta, V., Graham, S., Mirzaei, M. & You, Y., 1 Oct 2026, In: Neural Regeneration Research. 21, 10, p. 4822-4831 10 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)3 Downloads (Pure) -
Selective receptor modulation by truncated neuropeptide Y (3-36) dissociates vasoconstriction from neuroprotection in experimental glaucoma
Palanivel, V., Basavarajappa, D., Salkar, A., Komáromy, A. M., Tietz, O., Eva, T. A., Chitranshi, N., Mirzaei, M., Gupta, V., You, Y., Graham, S. L. & Gupta, V., Jan 2026, In: Molecular Neurobiology. 63, 1, p. 1-21 21 p., 334.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
The dynamic roles of repressor element 1-silencing transcription factor (REST): a double-edged sword in neural health and disease
Eva, T. A., Shenoy, A., Gupta, V. B., Palanivel, V., Salkar, A., Nasab, S. N., Chitranshi, N., Mirzaei, M., You, Y., Graham, S. L., Basavarajappa, D. & Gupta, V., Jan 2026, In: Molecular Neurobiology. 63, 1, p. 1-24 24 p., 46.Research output: Contribution to journal › Review article › peer-review
1 Link opens in a new tab Citation (Scopus)