• 618 Citations
  • 10 h-Index
20082019
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Research Outputs 2008 2019

  • 618 Citations
  • 10 h-Index
  • 13 Article
  • 1 Conference proceeding contribution
  • 1 Meeting abstract
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Article
2018

Dicer upregulation in differentiating monocytic cells by inhibition of specific proteolysis

Basavarajappa, D., Hedrich, S., Steinhilber, D., Samuelsson, B. & Radmark, O., 2018, (Submitted) In : Nature Communications.

Research output: Contribution to journalArticleResearchpeer-review

Prostaglandin E2 and Sphingosine-1-phosphate induced dicer upregulation and miRNAs formations in anti-inflammatory macrophages

Basavarajappa, D., Samuelsson, B. & Radmark, O., 2018, (In preparation) In : Blood.

Research output: Contribution to journalArticleResearchpeer-review

2015

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

Lehmann, C., Homann, J., Ball, A. K., Blöcher, R., Kleinschmidt, T. K., Basavarajappa, D., Angioni, C., Ferreirós, N., Häfner, A. K., Rådmark, O., Proschak, E., Haeggström, J. Z., Geisslinger, G., Parnham, M. J., Steinhilber, D. & Kahnt, A. S., 1 Dec 2015, In : FASEB Journal. 29, 12, p. 5029-5043 15 p.

Research output: Contribution to journalArticleResearchpeer-review

5-Lipoxygenase-Activating Proteins
Lipoxins
Biosynthesis
Arachidonate 5-Lipoxygenase
Neutrophils

P2X7 receptor regulates internalization of antimicrobial peptide LL-37 by human macrophages that promotes intracellular pathogen clearance

Tang, X., Basavarajappa, D., Haeggström, J. Z. & Wan, M., 1 Jan 2015, In : Journal of Immunology. 195, 3, p. 1191-1201 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Purinergic P2X7 Receptors
Macrophages
Clathrin
Endocytosis
Lysosomes

Tandem benzophenone amino pyridines, potent and selective inhibitors of human leukotriene C4 synthase

Kleinschmidt, T. K., Haraldsson, M., Basavarajappa, D., Lundeberg, E., Thulasingam, M., Ekoff, M., Fauland, A., Lehmann, C., Kahnt, A. S., Lindbom, L. & Haeggström, J. Z., 1 Oct 2015, In : Journal of Pharmacology and Experimental Therapeutics. 355, 1, p. 108-116 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pyridines
Leukotriene A4
Leukotriene E4
Peritoneal Lavage
Inflammation Mediators
2014

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., Basavarajappa, D., Rådmark, O., Kobayashi, S., Seibt, T., Beck, H., Neff, F., Esposito, I., Wanke, R., Förster, H., Yefremova, O. & 9 othersHeinrichmeyer, M., Bornkamm, G. W., Geissler, E. K., Thomas, S. B., Stockwell, B. R., Odonnell, V. B., Kagan, V. E., Schick, J. A. & Conrad, M., 1 Dec 2014, In : Nature Cell Biology. 16, 12, p. 1180-1191 12 p.

Research output: Contribution to journalArticleResearchpeer-review

phospholipid-hydroperoxide glutathione peroxidase
Acute Kidney Injury
Cell Death
Small Molecule Libraries
Cytoprotection

Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Basavarajappa, D., Wan, M., Lukic, A., Steinhilber, D., Samuelsson, B. & Rådmark, O., 5 Aug 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 31, p. 11371-11376 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5-Lipoxygenase-Activating Proteins
Leukotrienes
Arachidonate 5-Lipoxygenase
Proteins
Ionophores
2013

Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation

Rajala, R. V. S., Basavarajappa, D. K., Dighe, R. & Rajala, A., 18 Dec 2013, In : Cell Communication and Signaling. 11, 1, p. 1-11 11 p., 96.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Non-Receptor Type 1 Protein Tyrosine Phosphatase
Phosphorylation
Growth Factor Receptors
Insulin Receptor
Proteins
2011

Comparison of activity and conformational changes of ficin during denaturation by urea and guanidine hydrochloride

Devaraj, K. B., Kumar, P. R. & Prakash, V., 1 Feb 2011, In : Process Biochemistry. 46, 2, p. 458-464 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ficain
Denaturation
Guanidine
Urea
Enzymes

Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14

Basavarajappa, D. K., Gupta, V. K., Dighe, R., Rajala, A. & Rajala, R. V. S., 2011, In : Molecular and Cellular Biology. 31, 19, p. 3975-3987 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Non-Receptor Type 1 Protein Tyrosine Phosphatase
Growth Factor Receptors
Light
Proteins
Phosphorylation
2009

Characterization of acid-induced molten globule like state of ficin

Devaraj, K. B., Kumar, P. R. & Prakash, V., 1 Oct 2009, In : International Journal of Biological Macromolecules. 45, 3, p. 248-254 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ficain
Size exclusion chromatography
Fluorescence spectroscopy
Dichroism
Latexes
2008

An unusual thermostable aspartic protease from the latex of Ficus racemosa (L.)

Devaraj, K. B., Gowda, L. R. & Prakash, V., 1 Feb 2008, In : Phytochemistry. 69, 3, p. 647-655 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Ficus racemosa
Ficus
aspartic proteinases
Latex
latex

Purification, characterization, and solvent-induced thermal stabilization of ficin from Ficus carica

Devaraj, K. B., Kumar, P. R. & Prakash, V., 10 Dec 2008, In : Journal of Agricultural and Food Chemistry. 56, 23, p. 11417-11423 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ficain
ficain
Carica
Ficus
Ficus carica