Research output per year
Research output per year
Research Outputs
Search results
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2021
Identification of novel cathepsin B inhibitors with implications in Alzheimer’s disease: computational refining and biochemical evaluation
Chitranshi, N., Kumar, A., Sheriff, S., Gupta, V., Godinez, A., Saks, D., Sarkar, S., Shen, T., Mirzaei, M., Basavarajappa, D., Abyadeh, M., Singh, S. K., Dua, K., Zhang, K. Y. J., Graham, S. L. & Gupta, V., 31 Jul 2021, In: Cells. 10, 8, p. 1-30 30 p., 1946.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent manner
Abbasi, M., Gupta, V. K., Chitranshi, N., Gupta, V., Ranjbaran, R., Rajput, R., Maha Thananthirige, K. P., KB, D., You, Y., Salekdeh, G. H., Parton, R. G., Mirzaei, M. & Graham, S. L., 2021, In: Theranostics. 11, 13, p. 6154-6172 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
2020
Dicer up-regulation by inhibition of specific proteolysis in differentiating monocytic cells
Basavarajappa, D., Uebbing, S., Kreiss, M., Lukic, A., Suess, B., Steinhilber, D., Samuelsson, B. & Rådmark, O., 14 Apr 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 15, p. 8573-8583 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)5 Downloads (Pure) -
Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CLprotargeting repurposed drug candidates
Chitranshi, N., Gupta, V. K., Rajput, R., Godinez, A., Pushpitha, K., Shen, T., Mirzaei, M., You, Y., Basavarajappa, D., Gupta, V. & Graham, S. L., 9 Jul 2020, In: Journal of Translational Medicine. 18, 1, p. 1-15 15 p., 278.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)10 Downloads (Pure) -
2015
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein
Lehmann, C., Homann, J., Ball, A. K., Blöcher, R., Kleinschmidt, T. K., Basavarajappa, D., Angioni, C., Ferreirós, N., Häfner, A. K., Rådmark, O., Proschak, E., Haeggström, J. Z., Geisslinger, G., Parnham, M. J., Steinhilber, D. & Kahnt, A. S., 1 Dec 2015, In: FASEB Journal. 29, 12, p. 5029-5043 15 p.Research output: Contribution to journal › Article › peer-review
45 Citations (Scopus) -
P2X7 receptor regulates internalization of antimicrobial peptide LL-37 by human macrophages that promotes intracellular pathogen clearance
Tang, X., Basavarajappa, D., Haeggström, J. Z. & Wan, M., 1 Jan 2015, In: Journal of Immunology. 195, 3, p. 1191-1201 11 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Tandem benzophenone amino pyridines, potent and selective inhibitors of human leukotriene C4 synthase
Kleinschmidt, T. K., Haraldsson, M., Basavarajappa, D., Lundeberg, E., Thulasingam, M., Ekoff, M., Fauland, A., Lehmann, C., Kahnt, A. S., Lindbom, L. & Haeggström, J. Z., 1 Oct 2015, In: Journal of Pharmacology and Experimental Therapeutics. 355, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
2014
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., Basavarajappa, D., Rådmark, O., Kobayashi, S., Seibt, T., Beck, H., Neff, F., Esposito, I., Wanke, R., Förster, H., Yefremova, O. & 9 others, , 1 Dec 2014, In: Nature Cell Biology. 16, 12, p. 1180-1191 12 p.Research output: Contribution to journal › Article › peer-review
935 Citations (Scopus) -
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis
Basavarajappa, D., Wan, M., Lukic, A., Steinhilber, D., Samuelsson, B. & Rådmark, O., 5 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 31, p. 11371-11376 6 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
2013
Spatial and temporal aspects and the interplay of Grb14 and protein tyrosine phosphatase-1B on the insulin receptor phosphorylation
Rajala, R. V. S., Basavarajappa, D. K., Dighe, R. & Rajala, A., 18 Dec 2013, In: Cell Communication and Signaling. 11, 1, p. 1-11 11 p., 96.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
2011
Comparison of activity and conformational changes of ficin during denaturation by urea and guanidine hydrochloride
Devaraj, K. B., Kumar, P. R. & Prakash, V., 1 Feb 2011, In: Process Biochemistry. 46, 2, p. 458-464 7 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14
Basavarajappa, D. K., Gupta, V. K., Dighe, R., Rajala, A. & Rajala, R. V. S., 2011, In: Molecular and Cellular Biology. 31, 19, p. 3975-3987 13 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
2009
Characterization of acid-induced molten globule like state of ficin
Devaraj, K. B., Kumar, P. R. & Prakash, V., 1 Oct 2009, In: Journal of Energy Finance and Development. 45, 3, p. 248-254 7 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
2008
An unusual thermostable aspartic protease from the latex of Ficus racemosa (L.)
Devaraj, K. B., Gowda, L. R. & Prakash, V., 1 Feb 2008, In: Phytochemistry. 69, 3, p. 647-655 9 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Purification, characterization, and solvent-induced thermal stabilization of ficin from Ficus carica
Devaraj, K. B., Kumar, P. R. & Prakash, V., 10 Dec 2008, In: Journal of Agricultural and Food Chemistry. 56, 23, p. 11417-11423 7 p.Research output: Contribution to journal › Article › peer-review
59 Citations (Scopus)