• 1085 Citations
  • 15 h-Index
19962020
If you made any changes in Pure these will be visible here soon.

Personal profile

Biography

Dr Shklovskaya studied medicine in Russia, graduating with distinction before completing her PhD in the area of haematopoietic stem cell research in Russia and Switzerland. She undertook postdoctoral training in experimental haematology at the Research Department (ZLF) of Basel University Hospital in Switzerland, where she studied mechanisms of bone marrow failure and haematopoietic recovery after stem cell transplantation for malignancy. Her work into regulation of cytokine release underlying haematopoietic recovery received an ongoing support from the Swiss Cancer League and resulted in nine publications in international journals, including four in Blood. In 2002, Dr Shklovskaya moved to Australia and joined Professor Barbara Fazekas de St Groth at Centenary Institute in Sydney. She studied immune regulation in autoimmunity and cancer, combining complex transgenic animal models and multiparameter flow cytometry to discover a new paradigm in immunology - a population of antigen-presenting cells exclusively committed to maintaining immune tolerance on body surfaces. She also developed animal models to study adaptive immune responses in cancer, before moving into translational cancer immunology research and joining Professor Helen Rizos at MQ University in 2017. She is combining flow cytometry and in vitro models to gain insights into immune regulation in metastatic melanoma, particularly in patients who acquired resistance to immunotherapy.

Education/Academic qualification

Experimental Haematology, PhD, Russian Academy of Medical Sciences - Siberian Branch

Medicine, MBBS (Distinction), State Medical University Novosibirsk

Fingerprint Dive into the research topics where Elena Shklovskaya is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Aplastic Anemia Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Bone Marrow Cells Medicine & Life Sciences
T-Cell Antigen Receptor Medicine & Life Sciences
Langerhans Cells Medicine & Life Sciences
Immunity Medicine & Life Sciences
Bone Marrow Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2019 2020

Research Outputs 1996 2018

  • 1085 Citations
  • 15 h-Index
  • 30 Article
  • 2 Review article
  • 1 Chapter

Anti-PD-1-induced high-grade hepatitis associated with corticosteroid-resistant T cells: a case report

McGuire, H. M., Shklovskaya, E., Edwards, J., Trevillian, P. R., McCaughan, G. W., Bertolino, P., McKenzie, C., Gourlay, R., Gallagher, S. J., Fazekas de St. Groth, B. & Hersey, P., Apr 2018, In : Cancer Immunology, Immunotherapy. 67, 4, p. 563–573 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Hepatitis
Adrenal Cortex Hormones
T-Lymphocytes
Steroids
Antilymphocyte Serum

Interferon signaling is frequently downregulated in melanoma

Alavi, S., Stewart, A. J., Kefford, R. F., Lim, S. Y., Shklovskaya, E. & Rizos, H., 2018, In : Frontiers in Immunology. 9, p. 1-12 12 p., 1414.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Interferons
Interferon-gamma
Melanoma
Down-Regulation
Immunotherapy

Epigenetic modulation in cancer immunotherapy

Gallagher, S. J., Shklovskaya, E. & Hersey, P., 1 Aug 2017, In : Current Opinion in Pharmacology. 35, p. 48-56 9 p.

Research output: Contribution to journalReview articleResearchpeer-review

Epigenomics
Immunotherapy
Neoplasms
DNA Methylation
Acetylation

Collaboration between tumor-specific CD4(+) T cells and B cells in anti-cancer immunity

Guy, T. V., Terry, A. M., Bolton, H. A., Hancock, D. G., Zhu, E., Brink, R., McGuire, H. M., Shklovskaya, E. & Fazekas De St Groth, B., 24 May 2016, In : Oncotarget. 7, 21, p. 30211-30229 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Immunity
B-Lymphocytes
T-Lymphocytes
Neoplasms
Neoplasm Antibodies

Pro- and anti-tumour effects of B cells and antibodies in cancer: a comparison of clinical studies and preclinical models

Guy, T. V., Terry, A. M., Bolton, H. A., Hancock, D. G., Shklovskaya, E. & Fazekas de St Groth, B., 1 Aug 2016, In : Cancer Immunology, Immunotherapy. 65, 8, p. 885-896 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

B-Lymphocytes
Antibodies
Neoplasms
Neoplasm Antibodies
T-Lymphocytes

Prizes

ICB Best Publication of the Year award, 2016

Elena Shklovskaya (Recipient), Dec 2017

Prize: Other distinction

Allergy and Immunology
Publications
Cell Biology