Projects per year
Personal profile
Biography
Dr Fiona Bright completed a PhD in Medicine in 2017 at the University of Adelaide. Her PhD investigated the brainstem neuropathology underlying sudden infant death syndrome (SIDS). During her PhD, Fiona was awarded an International SIDS Fellowship funded by Rivers Gift and spent 18 months at Harvard University Medical School/Boston Childrens Hospital. Following this Fiona received the 2017 Kaarene Fitzgerald SIDS Postdoctoral Research Fellowship funded by RedNose Australia where she continued to undertake SIDS research at the University of Adelaide. In 2018, Fiona sought new challenges and took up a Postdoctoral role with the NHMRC Funded ForeFront research group at the University of Sydney, to investigate neuroimmune-mediated mechanisms in frontotemporal dementia (FTD). In 2020, Fiona was awarded a Macquarie University Research Fellowship (MQRF) to undertake research at the Dementia Research Centre with Prof Lars Ittner and Assoc Prof Yazi Ke.
Research interests
Fiona's current research interests include;
Neuroimmune and neuroinflammatory mechanisms/pathways underlying the neuropathology associated with neurodegeneration, with a specific focus on the innate immune complement cascade and TDP-43 pathology in frontotemporal dementia and amyotrophic lateral sclerosis.
Education/Academic qualification
Pathology/Neuroscience, PhD, Expression of substance P and the Tachykinin NK1 receptor in the medullary serotonergic network of the human infant during development: implications for sudden infant death syndrome (SIDS), The University of Adelaide
2013 → 2016
Award Date: 1 Mar 2017
Pathology , Honours (1st), The University of Adelaide
2012
Award Date: 31 Dec 2012
Health Science- Anatomy & Pathology , Bachelor, The University of Adelaide
2009 → 2011
Award Date: 31 Dec 2011
External positions
Honorary Affiliate Postdoctoral Fellow , University of Sydney
10 Feb 2020 → …
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Completing the tauopathy puzzle - modelling novel mutations to uncover unknown roles for tau in neurodevelopment and neurodegeneration
Bright, F., Cho, A. N., Morey, N. & Ittner, L.
1/04/23 → 1/04/25
Project: Research
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Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis
Katzeff, J. S., Bright, F., Phan, K., Kril, J. J., Ittner, L. M., Kassiou, M., Hodges, J. R., Piguet, O., Kiernan, M. C., Halliday, G. M. & Kim, W. S., 3 Jun 2022, In: Brain. 145, 5, p. 1598-1609 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile23 Citations (Scopus)73 Downloads (Pure) -
Efficient gene expression in human stem cell derived-cortical organoids using adeno associated virus
Cho, A-N., Bright, F., Morey, N., Au, C., Ittner, L. M. & Ke, Y. D., 11 Oct 2022, In: Cells. 11, 20, p. 1-13 13 p., 3194.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)65 Downloads (Pure) -
TSPO PET Imaging as a Biomarker of Neuroinflammation in Neurodegenerative Disorders
Werry, E. L., Bright, F. M. & Kassiou, M., 2022, Neuromethods diseases biomarkers: towards translating research to clinical practice. Peplow, P. V., Martinez, B. & Gennarelli, T. A. (eds.). New York: Humana Press Inc., p. 407-427 21 p. (Neuromethods; vol. 173).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Citations (Scopus) -
Glycoprotein pathways altered in frontotemporal dementia with autoimmune disease
Bright, F., Katzeff, J. S., Hodges, J. R., Piguet, O., Kril, J. J., Halliday, G. M. & Kim, W. S., 1 Sept 2021, In: Frontiers in Immunology. 12, p. 1-9 9 p., 736260.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)36 Downloads (Pure) -
TDP-43 and inflammation: implications for amyotrophic lateral sclerosis and frontotemporal dementia
Bright, F., Chan, G., van Hummel, A., Ittner, L. M. & Ke, Y. D., Aug 2021, In: International Journal of Molecular Sciences. 22, 15, p. 1-25 25 p., 7781.Research output: Contribution to journal › Review article › peer-review
Open AccessFile26 Citations (Scopus)64 Downloads (Pure)
Prizes
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River's Gift International SIDS Research Fellowship
Bright, Fiona (Recipient), 2014
Prize: Honorary award
Activities
- 1 Membership of committee
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Faculty of Medicine, Health and Human Sciences (Organisational unit)
Mitchell Sarkies (Member), Fiona Bright (Member), Katie De Luca (Member), Emre Ilhan (Member), Amy Nguyen (Member), Elizabeth Austin (Member), Ann Carrigan (Member), Karla Seaman (Member), Chris Bladen (Member), Annika van Hummel (Member), Jannah Baker (Member), Robert Ross (Member), Sian Genoud (Member), Emily Don (Chair), Nitin Chitranshi (Member), Rae-Anne Hardie (Chair), Rimante Ronto (Member), Gemma Sicouri (Member), Kelly Williams (Member), Syeda Somyyah Owais (Member), Anna Guller (Member), Robert Newport (Member), Marina Junqueira Santiago (Member), Philippe Gilchrist (Member), Jessamine Chen (Member), Ella Oar (Member), Alison Hogan (Member), Jodie Wills (Member), Kathleen Yin (Member), Gillian Hulst (Member), Benjamin Brown (Member), Loes Koring (Member), Stephney Whillier (Member), Milena Gandy (Member), Carly Johnco (Member), Lauren McLellan (Member) & Michael Swain (Member)
2020 → …Activity: Membership › Membership of committee