Projects per year
Personal profile
Biography
Flora Cheng obtained her Bachelor of Science majoring in Biology and Biochemistry at the University of New-Caledonia in 2014. She moved to Sydney to complete her Masters of Biotechnology and Business in 2016 and joined the Motor Neuron Disease Research Centre in 2017 as a research assistant in the Neuroproteomics Team under A. Prof. Albert Lee.
She is now a recipient of a FightMND Scholarship (2023-2026) and her research is focused on identifying and characterising the RNA-protein interaction of TDP-43 in motor neuron disease.
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Collaborations and top research areas from the last five years
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MNDA 25: Cryptic Peptides in Motor Neuron Disease: Unlocking Biomarkers and Therapeutic Targets
Lee, A. (Primary Chief Investigator), Rayner, S. (Chief Investigator), Cheng, F. (Chief Investigator) & Beheshti, A. (Chief Investigator)
1/06/26 → 31/05/27
Project: Research
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MNDRA PhD Top-Up Scholarship: Identification and characterisation of RNA-protein interaction in pathological aggregates of TDP-43 in MND
Cheng, F. (Primary Chief Investigator), Lee, A. (Supervisor), Rayner, S. (Chief Investigator), Morsch, M. (Chief Investigator) & Chung, R. (Chief Investigator)
30/04/24 → 29/04/27
Project: Research
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DRC25: Developing a test to evaluate therapeutic delivery
Davidson, J. (Primary Chief Investigator), Chung, R. (Associate Investigator), Lee, A. (Associate Investigator), Cheng, F. (Associate Investigator) & Chapman, T. (Associate Investigator)
15/05/25 → 14/05/26
Project: Research
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FightMND Scholarship: Identification and characterisation of RNA-protein interaction in pathological aggregates of TDP-43 in MND
Cheng, F. (Primary Chief Investigator), Lee, A. (Supervisor), Rayner, S. (Chief Investigator), Morsch, M. (Chief Investigator) & Chung, R. (Chief Investigator)
1/10/23 → 1/10/26
Project: Research
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ALS-FTD-linked CCNFS621G drives increased hippocampal astrocyte ramification and mitochondrial dysfunction and impairs motor neuron excitability
Robinson, L., Do-Ha, D., Cheng, F., Stevens, C. H., Porto, R. R., Coles, M., Subachandran, J., Kalajdzic, P., Lui, J., Balez, R., Muñoz, S. S., Cabral-da-Silva, M. C., Berg, T., Morsch, M., Lisowski, L., Tan, R. H., Burgio, G., Karl, T., Lee, A. & Chung, R. S. & 2 others, , Dec 2026, In: Journal of Neuroinflammation. 23, 1, p. 1-26 26 p., 208.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)6 Downloads (Pure) -
Differential inclusion formation of an aggregation-prone protein reveals differences in the proteostasis capacity of neuronal cell lines
McMahon, S., Cox, D., Cheng, F., Lee, A., Yerbury, J. J. & Ecroyd, H., Mar 2026, In: BBA - Molecular Cell Research. 1873, 3, p. 1-14 14 p., 120124.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
PolyQ-expanded ataxin-3 is associated with mitochondrial alterations in Machado–Joseph disease
Simó, I., Robinson, K. J., Kam, J. Y., Wang, Y., Kuriakose, A., Paric, E., Cheng, F., Potapenko, A., An, Y., Watchon, M., Lee, A. & Laird, A. S., 1 Sept 2026, In: DMM Disease Models and Mechanisms. 19, 9, p. 1-13 13 p., dmm052757.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Cardio-metabolic and cytoskeletal proteomic signatures differentiate stress hypersensitivity in dystrophin-deficient mdx mice
Major, G. S., Herbold, C. W., Cheng, F., Lee, A., Zhuang, S., Russell, A. P. & Lindsay, A., 20 Feb 2025, In: Journal of Proteomics. 312, p. 1-11 11 p., 105371.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)81 Downloads (Pure) -
Differential inclusion formation of an aggregation-prone protein reveals differences in the proteostasis capacity of neuronal cell lines
McMahon, S., Cox, D., Cheng, F., Lee, A., Yerbury, J. J. & Ecroyd, H., 29 Aug 2025, (Submitted) 32 p.Research output: Working paper › Preprint