Projects per year
Personal profile
Biography
Prof Gilles Guillemin has been working in the fields of Neuroimmunology and tryptophan metabolism for more than 20 years.
He is the Co-funder of the MND and Neurodegenerative Diseases Research Centre, The Co-funder of the Macquarie University MND Biobank and the Head of the Neuroinflammation group at Macquarie University.
Prof Guillemin’s team is one of the world’s leading research groups working on the involvement of the tryptophan catabolism (via the kynurenine pathway) in human neurodegenerative diseases.
He demonstrated the roles of this pathway in multiple sclerosis, Alzheimer's disease, amyotrophic lateral sclerosis, suicide…
He is the President of the International Society for Tryptophan Research and Editor-in-Chief of the International Journal for Tryptophan Research.
He has published more than 250 peer reviewed scientific articles. His current h-index is currently 59 and has more than 13.000 citations.
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Kynurenine
Medicine & Life Sciences
Quinolinic Acid
Medicine & Life Sciences
Astrocytes
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Tryptophan
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Oxidative Stress
Medicine & Life Sciences
Indoleamine-Pyrrole 2,3,-Dioxygenase
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2024
BDRC: Biomolecular Discovery Research Centre
Sunna, A., Packer, N., Paulsen, I., Guillemin, G., Li, M., Sofronov, G., Nadort, A., Haynes, P., Mabbutt, B., Tetu, S. & Andersen, M.
1/01/20 → 31/12/22
Project: Other
THE KYNURENINE PATHWAY IN NEUROINFLAMMATORY DISEASES: TRANSLATION TO PROGNOSTICS AND THERAPEUTICS
30/11/19 → 29/11/24
Project: Research
Etude Des Potentiels Anti-Inflammatoires De Plantes Utilisees Dans La Medecine Traditionnelle De Nouvelle-Caledonie
Matsui, M., Nour, M. & Guillemin, G.
4/05/19 → 1/10/20
Project: Other
Neurotoxicity induced by environmental amino acids-mimetic toxins through inflammation
Guillemin, G. & Mortaud, S.
1/01/19 → 31/12/22
Project: Research
File
Calpeptin, and related candidates, for the treatment of Machado Joseph disease
Laird, A., Nicholson, G., Walker, A. K., Cole, N., Lee, A., Morsch, M., Davis, R., Guillemin, G., Atkin, J. & Ooi, L.
1/01/18 → 31/12/21
Project: Research
Research Outputs 1993 2020
3Rs-based optimization of mice behavioral testing: the habituation/dishabituation olfactory test
Oummadi, A., Meyer-Dilhet, G., Béry, A., Aubert, A., Barone, P., Mortaud, S., Guillemin, G. J., Menuet, A. & Laugeray, A., 15 Feb 2020, In : Journal of Neuroscience Methods. 332, p. 1-15 15 p., 108550.Research output: Contribution to journal › Article › Research › peer-review
Translational Medical Research
Anti-Anxiety Agents
Laboratory Animals
Neurosciences
Intellectual Disability
Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression
Achtyes, E., Keaton, S. A., Smart, L. A., Burmeister, A. R., Heilman, P. L., Krzyzanowski, S., Nagalla, M., Guillemin, G. J., Escobar Galvis, M. L., Lim, C. K., Muzik, M., Postolache, T. T., Leach, R. & Brundin, L., 1 Jan 2020, In : Brain, Behavior, and Immunity. 83, p. 239-247 9 p.Research output: Contribution to journal › Article › Research › peer-review
Kynurenine
Depression
Inflammation
Peripartum Period
Serotonin
Amelioration of aluminum maltolate-induced inflammation and endoplasmic reticulum stress-mediated apoptosis by tannoid principles of Emblica officinalis in neuronal cellular model
Dhivya Bharathi, M., Justin-Thenmozhi, A., Manivasagam, T., Ahmad Rather, M., Saravana Babu, C., Mohamed Essa, M. & Guillemin, G. J., 1 Feb 2019, In : Neurotoxicity Research. 35, 2, p. 318-330 13 p.Research output: Contribution to journal › Article › Research › peer-review
Phyllanthus emblica
Endoplasmic Reticulum Stress
Eukaryotic Initiation Factor-2
Apoptosis
Inflammation
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress
Halloran, M., Ragagnin, A. M. G., Vidal, M., Parakh, S., Yang, S., Heng, B., Grima, N., Shahheydari, H., Soo, K-Y., Blair, I., Guillemin, G. J., Sundaramoorthy, V. & Atkin, J. D., 4 Dec 2019, In : Cellular and molecular life sciences. 15 p.Research output: Contribution to journal › Article › Research › peer-review
Endoplasmic Reticulum Stress
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum
Protein Transport
Endoplasmic Reticulum-Associated Degradation
Antioxidant therapies in attention deficit hyperactivity disorder
Moghadas, M., Essa, M. M., Ba-Omar, T., Al-Shehi, A., Qoronfleh, M. W., Eltayeb, E. A., Guillemin, G. J., Manivasagam, T., Justin-Thenmozhi, A., Al-Bulushi, B. S., Al-Adawi, S. & Edalatmanesh, M. A., 1 Jan 2019, In : Frontiers in bioscience (Landmark edition). 24, 2, p. 313-333 21 p.Research output: Contribution to journal › Article › Research › peer-review
Attention Deficit Disorder with Hyperactivity
Antioxidants
Pediatrics
Oxidative stress
Cell membranes
Activities 2015 2018
International Society for Tryptophan Research (Executive Committee) (External organisation)
Gilles Guillemin (Chair), Florian Zepf (Chair), Trevor Stone (Member), Kuniaki Saito (Member), Sophie Erhardt (Member), Edwin Lim (Member)2018 → …
Activity: Membership › Membership of committee
International Journal of Tryptophan Research (Journal)
Gilles Guillemin (Editor in chief), Edwin Lim (Editor in chief)2015 → …
Activity: Publication peer-review and editorial work › Editorial work