Projects per year
Personal profile
Biography
Prof Gilles Guillemin has been working in the fields of Neuroimmunology and tryptophan metabolism for more than 20 years.
He is the Co-funder of the MND and Neurodegenerative Diseases Research Centre, The Co-funder of the Macquarie University MND Biobank and the Head of the Neuroinflammation group at Macquarie University.
Prof Guillemin’s team is one of the world’s leading research groups working on the involvement of the tryptophan catabolism (via the kynurenine pathway) in human neurodegenerative diseases.
He demonstrated the roles of this pathway in multiple sclerosis, Alzheimer's disease, amyotrophic lateral sclerosis, suicide…
He is the President of the International Society for Tryptophan Research and Editor-in-Chief of the International Journal for Tryptophan Research.
He has published more than 200 peer reviewed scientific articles. His current h-index is currently 51 and has more than 10.000 citations.
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Kynurenine
Medicine & Life Sciences
Quinolinic Acid
Medicine & Life Sciences
Astrocytes
Medicine & Life Sciences
Alzheimer Disease
Medicine & Life Sciences
Tryptophan
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Oxidative Stress
Medicine & Life Sciences
Brain
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2024
Etude Des Potentiels Anti-Inflammatoires De Plantes Utilisees Dans La Medecine Traditionnelle De Nouvelle-Caledonie
Matsui, M., Nour, M. & Guillemin, G.
4/05/19 → 1/10/20
Project: Other
Calpeptin, and related candidates, for the treatment of Machado Joseph disease
Laird, A., Nicholson, G., Walker, A., Cole, N., Lee, A., Morsch, M., Davis, R., Guillemin, G., Atkin, J. & Ooi, L.
1/01/18 → 31/12/21
Project: Research
Acoustic liquid handling robotics for bioactive compound discovery
Karuso, P., Poulsen, S., Avery, V., Quinn, R., Jonathan, B., Scanlon, M., Cooper, M., Booker, G., Professor, S., Guillemin, G., Smith, J., Ryan, J. & Peat, T.
10/03/17 → …
Project: Research
Slowing progression of Alzheimer's disease by modulating the kynurenine pathway
Guillemin, G., Lovejoy, D., Ittner, A., Braidy, N., Doecke, J., Lim, C., Nicolazzo, J. & Ittner, L.
1/01/17 → …
Project: Research
Macquarie University Centre for Motor Neuron Disease Research
Blair, I., Rowe, D., Guillemin, G., Chung, R., Atkin, J., Cole, N., Laird, A., Lim, C., Williams, K., Yang, S., Morsch, M., Lee, A., Shi, B., Walker, A., Lovejoy, D., Furlong, S., Adams, L., Syal, D., Bazzi, R., Svahn, A., Parakh, S., Shahheydari, H., Konopka, A., Ragagnin, A., Mehta, P., Wright, A., Bourbon, L., Sabaretnam, T., Don, E., Hortle, E., De Luca, A., Zhang, K., Tarr, I., Galper, J., Varney, B., Chow, S. & Formella, I.
1/01/17 → 31/12/19
Project: Research
Research Outputs 1993 2019
Amelioration of aluminum maltolate-induced inflammation and endoplasmic reticulum stress-mediated apoptosis by tannoid principles of Emblica officinalis in neuronal cellular model
Dhivya Bharathi, M., Justin-Thenmozhi, A., Manivasagam, T., Ahmad Rather, M., Saravana Babu, C., Mohamed Essa, M. & Guillemin, G. J., 1 Feb 2019, In : Neurotoxicity Research. 35, 2, p. 318-330 13 p.Research output: Contribution to journal › Article › Research › peer-review
Phyllanthus emblica
Endoplasmic Reticulum Stress
Eukaryotic Initiation Factor-2
Apoptosis
Inflammation
Antioxidant therapies in attention deficit hyperactivity disorder
Moghadas, M., Essa, M. M., Ba-Omar, T., Al-Shehi, A., Qoronfleh, M. W., Eltayeb, E. A., Guillemin, G. J., Manivasagam, T., Justin-Thenmozhi, A., Al-Bulushi, B. S., Al-Adawi, S. & Edalatmanesh, M. A., 1 Jan 2019, In : Frontiers in bioscience (Landmark edition). 24, 2, p. 313-333 21 p.Research output: Contribution to journal › Article › Research › peer-review
Attention Deficit Disorder with Hyperactivity
Antioxidants
Pediatrics
Oxidative stress
Cell membranes
Asiatic acid attenuated aluminum chloride-induced tau pathology, oxidative stress and apoptosis via AKT/GSK-3β signaling pathway in Wistar rats
Ahmad Rather, M., Justin-Thenmozhi, A., Manivasagam, T., Saravanababu, C., Guillemin, G. J. & Essa, M. M., 15 May 2019, In : Neurotoxicity Research. 35, 4, p. 955-968 14 p.Research output: Contribution to journal › Article › Research › peer-review
Oxidative stress
Pathology
Wistar Rats
Rats
Oxidative Stress
Chemical reprogramming enhances homology-directed genome editing in zebrafish embryos
Aksoy, Y. A., Nguyen, D. T., Chow, S., Chung, R. S., Guillemin, G. J., Cole, N. J. & Hesselson, D., 23 May 2019, In : Communications Biology. 2, p. 1-9 9 p., 198.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Zebrafish
Embryonic Structures
Clustered Regularly Interspaced Short Palindromic Repeats
DNA Repair
DNA
Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer’s disease and relationship to amyloid-β and tau
Jacobs, K., Lim, C. K., Blennow, K., Zetterberg, H., Chatterjee, P., Martins, R. N., Brew, B., Guillemin, G. & Lovejoy, D., 1 Apr 2019, (Accepted/In press) In : Neurobiology of Aging. 80, p. 11-20 10 p.Research output: Contribution to journal › Article › Research › peer-review
Kynurenine
Amyloid
Cerebrospinal Fluid
Alzheimer Disease
Quinolinic Acid
Activities 2015 2018
International Society for Tryptophan Research (Executive Committee) (External organisation)
Gilles Guillemin (Chair), Florian Zepf (Chair), Trevor Stone (Member), Kuniaki Saito (Member), Sophie Erhardt (Member), Edwin Lim (Member)2018 → …
Activity: Membership › Membership of committee
International Journal of Tryptophan Research (Journal)
Gilles Guillemin (Editor in chief), Edwin Lim (Editor in chief)2015 → …
Activity: Publication peer-review and editorial work › Editorial work