Gilles Guillemin

Professor

NHMRC Leadership Fellow, Department of Biomedical Sciences
Macquarie University Centre for Motor Neuron Disease Research
Biomolecular Discovery Research Centre

https://orcid.org/0000-0001-8105-4470

Phone+61 2 9850 2727
Emailgilles.guillemin@mq.edu.au

Source: Scopus
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Personal profile

Biography

Prof Gilles Guillemin has been working in the fields of Neuroimmunology and tryptophan metabolism for more than 20 years.

He is the Co-funder of the MND and Neurodegenerative Diseases Research Centre, The Co-funder of the Macquarie University MND Biobank and the Head of the Neuroinflammation group at Macquarie University.

Prof Guillemin’s team is one of the world’s leading research groups working on the involvement of the tryptophan catabolism (via the kynurenine pathway) in human neurodegenerative diseases.

He demonstrated the roles of this pathway in multiple sclerosis, Alzheimer's disease, amyotrophic lateral sclerosis, suicide…

He is the President of the International Society for Tryptophan Research and Editor-in-Chief of the International Journal for Tryptophan Research.

He has published more than 250 peer reviewed scientific articles. His current h-index is currently 66 and has more than 15.000 citations.

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15 Active
34 Finished

Modulating actin dynamics in ALS/MND as a novel therapeutic approach
Atkin, J., Woodruff, T. M., Karl, T., Craik, D., Guillemin, G. & Laird, A.
4/01/21 → 3/01/24
Project: Research
Biomarker-based identification of at-risk patients with COVID-19
Guillemin, G. & Brew, B.
1/06/20 → 31/12/21
Project: Research

File
The kynurenine pathway in neuroinflammatory diseases: Translation to prognostics and therapeutics
Guillemin, G.
1/01/20 → 31/12/24
Project: Other
CMNDR: Macquarie University Centre for Motor Neuron Disease Research
Atkin, J., Blair, I., Rowe, D., Atkin, J., Chung, R., Guillemin, G., Laird, A., Lee, A., Morsch, M., Shi, B., Williams, K. & Yang, S.
1/01/20 → 31/12/22
Project: Other
THE KYNURENINE PATHWAY IN NEUROINFLAMMATORY DISEASES: TRANSLATION TO PROGNOSTICS AND THERAPEUTICS
Guillemin, G.
30/11/19 → 29/11/24
Project: Research

13333 Citations
59 h-Index
227 Article
50 Review article
28 Chapter
19 Meeting abstract
More

Detrimental activation of AhR pathway in cancer: an overview of therapeutic strategies
Leclerc, D., Staats Pires, A. C., Guillemin, G. J. & Gilot, D., 1 Jun 2021, In: Current Opinion in Immunology. 70, p. 15-26 12 p.
Research output: Contribution to journal › Review article › peer-review
2 Citations (Scopus)
Does exercise influence kynurenine/tryptophan metabolism and psychological outcomes in persons with age-related diseases? A systematic review
Lim, A., Harijanto, C., Vogrin, S., Guillemin, G. & Duque, G., 1 Jan 2021, In: International Journal of Tryptophan Research. 14, p. 1-13 13 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File
Is exposure to BMAA a risk factor for neurodegenerative diseases? A response to a critical review of the BMAA hypothesis
Dunlop, R. A., Banack, S. A., Bishop, S. L., Metcalf, J. S., Murch, S. J., Davis, D. A., Stommel, E. W., Karlsson, O., Brittebo, E. B., Chatziefthimiou, A. D., Tan, V. X., Guillemin, G. J., Cox, P. A., Chatziefthimiou, D. C. & Bradley, W. G., Feb 2021, In: Neurotoxicity Research. 39, 1, p. 81-106 26 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
31 Downloads (Pure)
Machine learning workflows identify a microRNA signature of insulin transcription in human tissues
Wong, W. K. M., Joglekar, M. V., Saini, V., Jiang, G., Dong, C. X., Chaitarvornkit, A., Maciag, G. J., Gerace, D., Farr, R. J., Satoor, S. N., Sahu, S., Sharangdhar, T., Ahmed, A. S., Chew, Y. V., Liuwantara, D., Heng, B., Lim, C. K., Hunter, J., Januszewski, A. S., Sørensen, A. E. & 13 others, Akil, A. S. A., Gamble, J. R., Loudovaris, T., Kay, T. W., Thomas, H. E., O'Connell, P. J., Guillemin, G. J., Martin, D., Simpson, A. M., Hawthorne, W. J., Dalgaard, L. T., Ma, R. C. W. & Hardikar, A. A., 23 Apr 2021, In: iScience. 24, 4, p. 1-19 47 p., 102379.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Downloads (Pure)
Papaverine, a phosphodiesterase 10A inhibitor, ameliorates Quinolinic acid-induced synaptotoxicity in human cortical neurons
Bhat, A., Tan, V., Heng, B., Chow, S., Basappa, S., Essa, M. M., Chidambaram, S. B. & Guillemin, G. J., 29 Apr 2021, In: Neurotoxicity Research. 13 p.
Research output: Contribution to journal › Article › peer-review

1 Editorial work
1 Membership of committee

International Society for Tryptophan Research (Executive Committee) (External organisation)
Gilles Guillemin (Chair), Florian Zepf (Chair), Trevor Stone (Member), Kuniaki Saito (Member), Sophie Erhardt (Member) & Edwin Lim (Member)
2018 → …
Activity: Membership › Membership of committee
International Journal of Tryptophan Research (Journal)
Gilles Guillemin (Editor in chief) & Edwin Lim (Editor in chief)
2015 → …
Activity: Peer-review and editorial of research outputs › Editorial work