Gilles Guillemin


  • 10531 Citations
  • 52 h-Index
1993 …2024
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Personal profile


Prof Gilles Guillemin has been working in the fields of Neuroimmunology and tryptophan metabolism for more than 20 years.

He is the Co-funder of the MND and Neurodegenerative Diseases Research Centre, The Co-funder of the Macquarie University MND Biobank and the Head of the Neuroinflammation group at Macquarie University.

Prof Guillemin’s team is one of the world’s leading research groups working on the involvement of the tryptophan catabolism (via the kynurenine pathway) in human neurodegenerative diseases.

He demonstrated the roles of this pathway in multiple sclerosis, Alzheimer's disease, amyotrophic lateral sclerosis, suicide…

He is the President of the International Society for Tryptophan Research and Editor-in-Chief of the International Journal for Tryptophan Research.

He has published more than 250 peer reviewed scientific articles. His current h-index is currently 59 and has more than 13.000 citations.

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Kynurenine Medicine & Life Sciences
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Indoleamine-Pyrrole 2,3,-Dioxygenase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2024

Research Outputs 1993 2020

3Rs-based optimization of mice behavioral testing: the habituation/dishabituation olfactory test

Oummadi, A., Meyer-Dilhet, G., Béry, A., Aubert, A., Barone, P., Mortaud, S., Guillemin, G. J., Menuet, A. & Laugeray, A., 15 Feb 2020, In : Journal of Neuroscience Methods. 332, p. 1-15 15 p., 108550.

Research output: Contribution to journalArticleResearchpeer-review

Translational Medical Research
Anti-Anxiety Agents
Laboratory Animals
Intellectual Disability

Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression

Achtyes, E., Keaton, S. A., Smart, L. A., Burmeister, A. R., Heilman, P. L., Krzyzanowski, S., Nagalla, M., Guillemin, G. J., Escobar Galvis, M. L., Lim, C. K., Muzik, M., Postolache, T. T., Leach, R. & Brundin, L., 1 Jan 2020, In : Brain, Behavior, and Immunity. 83, p. 239-247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Peripartum Period

Amelioration of aluminum maltolate-induced inflammation and endoplasmic reticulum stress-mediated apoptosis by tannoid principles of Emblica officinalis in neuronal cellular model

Dhivya Bharathi, M., Justin-Thenmozhi, A., Manivasagam, T., Ahmad Rather, M., Saravana Babu, C., Mohamed Essa, M. & Guillemin, G. J., 1 Feb 2019, In : Neurotoxicity Research. 35, 2, p. 318-330 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Phyllanthus emblica
Endoplasmic Reticulum Stress
Eukaryotic Initiation Factor-2

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

Halloran, M., Ragagnin, A. M. G., Vidal, M., Parakh, S., Yang, S., Heng, B., Grima, N., Shahheydari, H., Soo, K-Y., Blair, I., Guillemin, G. J., Sundaramoorthy, V. & Atkin, J. D., 4 Dec 2019, In : Cellular and molecular life sciences. 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Endoplasmic Reticulum Stress
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum
Protein Transport
Endoplasmic Reticulum-Associated Degradation

Antioxidant therapies in attention deficit hyperactivity disorder

Moghadas, M., Essa, M. M., Ba-Omar, T., Al-Shehi, A., Qoronfleh, M. W., Eltayeb, E. A., Guillemin, G. J., Manivasagam, T., Justin-Thenmozhi, A., Al-Bulushi, B. S., Al-Adawi, S. & Edalatmanesh, M. A., 1 Jan 2019, In : Frontiers in bioscience (Landmark edition). 24, 2, p. 313-333 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Attention Deficit Disorder with Hyperactivity
Oxidative stress
Cell membranes

Activities 2015 2018

  • 1 Editorial work
  • 1 Membership of committee

International Society for Tryptophan Research (Executive Committee) (External organisation)

Gilles Guillemin (Chair), Florian Zepf (Chair), Trevor Stone (Member), Kuniaki Saito (Member), Sophie Erhardt (Member), Edwin Lim (Member)
2018 → …

Activity: MembershipMembership of committee

International Journal of Tryptophan Research (Journal)

Gilles Guillemin (Editor in chief), Edwin Lim (Editor in chief)
2015 → …

Activity: Publication peer-review and editorial workEditorial work