• 11262 Citations
  • 55 h-Index
1993 …2024

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Research Outputs

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Review article
2019

Dendritic spines: revisiting the physiological role

Chidambaram, S. B., Rathipriya, A. G., Bolla, S. R., Bhat, A., Ray, B., Mahalakshmi, A. M., Manivasagam, T., Thenmozhi, A. J., Essa, M. M., Guillemin, G. J., Chandra, R. & Sakharkar, M. K., 8 Jun 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 92, p. 161-193 33 p.

Research output: Contribution to journalReview article

13 Citations (Scopus)

Fungal-contaminated grass and well water and sporadic amyotrophic lateral sclerosis

French, P. W., Ludowyke, R. I. & Guillemin, G. J., 1 Sep 2019, In : Neural Regeneration Research. 14, 9, p. 1490-1493 4 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
13 Downloads (Pure)

Human tick-borne diseases in Australia

Dehhaghi, M., Kazemi Shariat Panahi, H., Holmes, E. C., Hudson, B. J., Schloeffel, R. & Guillemin, G. J., 28 Jan 2019, In : Frontiers in cellular and infection microbiology. 9, p. 1-17 17 p., 3.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
77 Downloads (Pure)

Kynurenine pathway metabolites as biomarkers for Amyotrophic Lateral Sclerosis

Tan, V. X. & Guillemin, G. J., 20 Sep 2019, In : Frontiers in Neuroscience. 13, p. 1-11 11 p., 1013.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)

Microbiota alterations in Alzheimer’s disease: involvement of the kynurenine pathway and inflammation

Garcez, M. L., Jacobs, K. R. & Guillemin, G. J., 15 Aug 2019, In : Neurotoxicity Research. 36, 2, p. 424-436 13 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
3 Citations (Scopus)

The plasma [Kynurenine]/[Tryptophan] ratio and indoleamine 2,3-dioxygenase: time for appraisal

Badawy, A. A-B. & Guillemin, G., 1 Aug 2019, In : International Journal of Tryptophan Research. 12, p. 1-10 10 p.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
1 Downloads (Pure)
2018

Microorganisms’ footprint in neurodegenerative diseases

Dehhaghi, M., Kazemi Shariat Panahi, H. & Guillemin, G. J., 4 Dec 2018, In : Frontiers in Cellular Neuroscience. 12, p. 1-17 17 p., 466.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
3 Downloads (Pure)
2017

Bcl11b-A critical neurodevelopmental transcription factor-roles in health and disease

Lennon, M. J., Jones, S. P., Lovelace, M. D., Guillemin, G. J. & Brew, B. J., 29 Mar 2017, In : Frontiers in Cellular Neuroscience. 11, p. 1-7 7 p., 89.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
4 Downloads (Pure)

Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis

Lee, J. M., Tan, V., Lovejoy, D., Braidy, N., Rowe, D. B., Brew, B. J. & Guillemin, G. J., Jan 2017, In : Neuropharmacology. 112, p. 346-364 19 p.

Research output: Contribution to journalReview article

12 Citations (Scopus)

Major developments in the design of inhibitors along the kynurenine pathway

Jacobs, K. R., Castellano-Gonzalez, G., Guillemin, G. J. & Lovejoy, D. B., 2017, In : Current medicinal chemistry. 24, 23, p. 2471-2495 25 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Protective effect of antioxidants on neuronal dysfunction and plasticity in Huntington's disease

Velusamy, T., Panneerselvam, A. S., Purushottam, M., Anusuyadevi, M., Pal, P. K., Jain, S., Essa, M. M., Guillemin, G. J. & Kandasamy, M., 2017, In : Oxidative Medicine and Cellular Longevity. 2017, p. 1-15 15 p., 3279061.

Research output: Contribution to journalReview article

Open Access
File
22 Citations (Scopus)
14 Downloads (Pure)

Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases

Lovelace, M. D., Varney, B., Sundaram, G., Lennon, M. J., Lim, C. K., Jacobs, K., Guillemin, G. J. & Brew, B. J., 1 Jan 2017, In : Neuropharmacology. 112, PartB, p. 373-388 16 p.

Research output: Contribution to journalReview article

95 Citations (Scopus)
2016

Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?

Lennon, M. J., Jones, S. P., Lovelace, M. D., Guillemin, G. J. & Brew, B. J., 1 Feb 2016, In : Neurotoxicity Research. 29, 2, p. 201-207 7 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Current evidence for a role of the kynurenine pathway of tryptophan metabolism in multiple sclerosis

Lovelace, M. D., Varney, B., Sundaram, G., Franco, N. F., Ng, M. L., Pai, S., Lim, C. K., Guillemin, G. J. & Brew, B. J., 4 Aug 2016, In : Frontiers in Immunology. 7, p. 1-22 22 p., 246.

Research output: Contribution to journalReview article

Open Access
File
44 Citations (Scopus)
69 Downloads (Pure)

Kynurenine-3-monooxygenase: A review of structure, mechanism, and inhibitors

Smith, J. R., Jamie, J. F. & Guillemin, G. J., Feb 2016, In : Drug Discovery Today. 21, 2, p. 315-324 10 p.

Research output: Contribution to journalReview article

32 Citations (Scopus)

Kynurenines, gender and neuroinflammation; showcase schizophrenia

de Bie, J., Lim, C. K. & Guillemin, G. J., 1 Oct 2016, In : Neurotoxicity Research. 30, 3, p. 285-294 10 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease: A Mini Review

Manoharan, S., Guillemin, G. J., Abiramasundari, R. S., Essa, M. M., Akbar, M. & Akbar, M. D., 2016, In : Oxidative Medicine and Cellular Longevity. 2016, p. 1-15 15 p., 8590578.

Research output: Contribution to journalReview article

Open Access
File
136 Citations (Scopus)
63 Downloads (Pure)
2015

Neuroinflammation in multiple system atrophy: Response to and cause of α-synuclein aggregation

Vieira, B. D. M., Radford, R. A., Chung, R. S., Guillemin, G. J. & Pountney, D. L., 12 Nov 2015, In : Frontiers in Cellular Neuroscience. 9, p. 1-9 9 p., 437.

Research output: Contribution to journalReview article

Open Access
File
38 Citations (Scopus)
33 Downloads (Pure)

Pharmacological benefits of active components of natural products against traumatic brain injury - A review

Subash, S., Essa, M. M., Al-Adawi, S., Memon, M. A., Manivasagam, T., Thenmozhi, A. J., Akbar, M., Song, B. J. & Guillemin, G. J., 1 Aug 2015, In : Current Pharmacogenomics and Personalized Medicine. 13, 2, p. 99-116 18 p.

Research output: Contribution to journalReview article

2013

Excitotoxicity in the pathogenesis of autism

Essa, M. M., Braidy, N., Vijayan, K. R., Subash, S. & Guillemin, G. J., May 2013, In : Neurotoxicity Research. 23, 4, p. 393-400 8 p.

Research output: Contribution to journalReview article

43 Citations (Scopus)

The kynurenine pathway in stem cell biology

Jones, S. P., Guillemin, G. J. & Brew, B. J., 2013, In : International Journal of Tryptophan Research. 6, p. 57-66 10 p.

Research output: Contribution to journalReview article

Open Access
File
23 Citations (Scopus)
7 Downloads (Pure)
2012

Kynurenine pathway in skin cells: Implications for UV-induced skin damage

Sheipouri, D., Braidy, N. & Guillemin, G. J., 2012, In : International Journal of Tryptophan Research. 5, 1, p. 15-25 11 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
20 Downloads (Pure)

NAD(+) metabolism and oxidative stress: the golden nucleotide on a crown of thorns

Massudi, H., Grant, R., Guillemin, G. J. & Braidy, N., Jan 2012, In : Redox Report. 17, 1, p. 28-46 19 p.

Research output: Contribution to journalReview article

60 Citations (Scopus)

Neuroprotective effect of natural products against Alzheimer's disease

Essa, M. M., Vijayan, R. K., Castellano-Gonzalez, G., Memon, M. A., Braidy, N. & Guillemin, G. J., Sep 2012, In : Neurochemical Research. 37, 9, p. 1829-1842 14 p.

Research output: Contribution to journalReview article

141 Citations (Scopus)

Quinolinic acid, the inescapable neurotoxin

Guillemin, G. J., Apr 2012, In : FEBS Journal. 279, 8, p. 1356-1365 10 p.

Research output: Contribution to journalReview article

207 Citations (Scopus)

Recent rodent models for Alzheimer's disease: Clinical implications and basic research

Braidy, N., Muñoz, P., Palacios, A. G., Castellano-Gonzalez, G., Inestrosa, N. C., Chung, R. S., Sachdev, P. & Guillemin, G. J., Feb 2012, In : Journal of Neural Transmission. 119, 2, p. 173-195 23 p.

Research output: Contribution to journalReview article

70 Citations (Scopus)

The crossroads of neuroinflammation in infectious diseases: Endothelial cells and astrocytes

Combes, V., Guillemin, G. J., Chan-Ling, T., Hunt, N. H. & Grau, G. E. R., Aug 2012, In : Trends in Parasitology. 28, 8, p. 311-319 9 p.

Research output: Contribution to journalReview article

34 Citations (Scopus)

The kynurenine pathway in brain tumor pathogenesis

Adams, S., Braidy, N., Bessesde, A., Brew, B. J., Grant, R., Teo, C. & Guillemin, G. J., 15 Nov 2012, In : Cancer Research. 72, 22, p. 5649-5657 9 p.

Research output: Contribution to journalReview article

72 Citations (Scopus)
2011

The involvement of neuroinflammation and Kynurenine pathway in Parkinson's disease

Zinger, A., Barcia, C., Herrero, M. T. & Guillemin, G. J., Jan 2011, In : Parkinson's Disease. 2011, p. 1-11 11 p., 716859.

Research output: Contribution to journalReview article

Open Access
File
45 Citations (Scopus)
24 Downloads (Pure)
2010

Tryptophan, neurodegeneration and HIV-associated neurocognitive disorder

Davies, N. W. S., Guillemin, G. & Brew, B. J., 2010, In : International Journal of Tryptophan Research. 3, 1, p. 121-140 20 p.

Research output: Contribution to journalReview article

Open Access
File
28 Citations (Scopus)
39 Downloads (Pure)

Understanding the roles of the kynurenine pathway in multiple sclerosis progression

Lim, C. K., Brew, B. J., Sundaram, G. & Guillemin, G. J., 2010, In : International Journal of Tryptophan Research. 3, 1, p. 157-167 11 p.

Research output: Contribution to journalReview article

Open Access
File
39 Citations (Scopus)
17 Downloads (Pure)
2009

Kynurenine pathway metabolites in humans: disease and healthy States

Chen, Y. & Guillemin, G. J., 2009, In : International Journal of Tryptophan Research. 2, 1, p. 1-19 19 p.

Research output: Contribution to journalReview article

Open Access
File
304 Citations (Scopus)
33 Downloads (Pure)

Neurodegeneration and ageing in the HAART era

Brew, B. J., Crowe, S. M., Landay, A., Cysique, L. A. & Guillemin, G., Jun 2009, In : Journal of Neuroimmune Pharmacology. 4, 2, p. 163-174 12 p.

Research output: Contribution to journalReview article

124 Citations (Scopus)

Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors

Chen, Y., Meininger, V. & Guillemin, G. J., Mar 2009, In : Central Nervous System Agents in Medicinal Chemistry. 9, 1, p. 32-39 8 p.

Research output: Contribution to journalReview article

27 Citations (Scopus)
2007

The involvement of astrocytes and kynurenine pathway in Alzheimer's disease

Ting, K. K., Brew, B. & Guillemin, G., 2007, In : Neurotoxicity Research. 12, 4, p. 247-262 16 p.

Research output: Contribution to journalReview article

34 Citations (Scopus)
2006

Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis

Guillemin, G. J., Meininger, V. & Brew, B. J., Jan 2006, In : Neurodegenerative Diseases. 2, 3-4, p. 166-176 11 p.

Research output: Contribution to journalReview article

69 Citations (Scopus)
2005

Involvement of quinolinic acid in AIDS dementia complex

Guillemin, G. J., Kerr, S. J. & Brew, B. J., 2005, In : Neurotoxicity Research. 7, 1-2, p. 103-123 21 p.

Research output: Contribution to journalReview article

100 Citations (Scopus)
2004

Microglia, macrophages, perivascular macrophages, and pericytes: A review of function and identification

Guillemin, G. J. & Brew, B. J., Mar 2004, In : Journal of Leukocyte Biology. 75, 3, p. 388-397 10 p.

Research output: Contribution to journalReview article

385 Citations (Scopus)
2002

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

Guillemin, G. J. & Brew, B. J., 2002, In : Redox Report. 7, 4, p. 199-206 8 p.

Research output: Contribution to journalReview article

123 Citations (Scopus)