Personal profile
Biography
Dr. Grant Richter is an early career postdoctoral research fellow at the Centre for MND Research at Macquarie University, with a research focus on characterizing pathological MND-related proteins within living cells and developing drugs to treat MND.
He obtained his PhD from the University of Sydney, where he trained as an electrophysiologist and animal surgeon investigating rodent models of stroke. His dissertation, titled "GABA Drugs for Motor Recovery After Stroke," highlights some crucial differences in a drug’s efficacy between human clinical patients and mouse models of stroke. His electrophysiology work produced significant findings that were published in a 2020 Frontiers in Neuroscience article.
In 2022, Dr. Richter was recruited to the Morsch Lab at Macquarie University, where he began working with zebrafish – a model system he was first exposed to during his master’s studies in the Centre for Neuroregeneration at the University of Edinburgh. Dr. Richter excels in the cutting-edge techniques of live confocal microscopy of zebrafish motor neurons and advanced computer image analysis.
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Collaborations and top research areas from the last five years
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MND 24: What’s upstream of loss of nuclear TDP-43 function? -The impact of phosphorylation on RNA binding
Richter, G. (Primary Chief Investigator), Maurel, C. (Chief Investigator), Rayner, S. (Chief Investigator) & Morsch, M. (Associate Investigator)
20/06/25 → 20/06/26
Project: Research
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MNDRA24: Probing molecular drivers of TDP-43 phase transition: the influence of lysine modifications.
Maurel, C. (Primary Chief Investigator), Richter, G. (Chief Investigator) & Morsch, M. (Chief Investigator)
1/06/24 → 31/05/25
Project: Research
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Characterising the interactome of sequestosome-1/(p62) – the peacemaker between protein homeostasis and dysfunction
Davidson, J. (Primary Chief Investigator), Lee, A. (Chief Investigator), Morsch, M. (Chief Investigator), Richter, G. (Chief Investigator), Rea, S. (Chief Investigator) & Di Ieva, A. (Chief Investigator)
14/03/23 → 14/03/24
Project: Research
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Characterising the interactome of sequestosome-1 (p62) – the peacemaker between protein homeostasis and dysfunction
Davidson, J. (Primary Chief Investigator), Lee, A. (Co-Investigator), Morsch, M. (Co-Investigator), Richter, G. (Co-Investigator), Di Ieva, A. (Co-Investigator) & Rea, S. (Co-Investigator)
1/01/23 → 31/12/23
Project: Research
Research Outputs
- 3 Article
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Protocol for characterizing biomolecular condensates through live-cell imaging and analysis
Richter, G., Maurel, C., Hogan, A., Radford, R. A. W., Lee, A., Chung, R. S. & Morsch, M., 19 Sept 2025, In: STAR Protocols. 6, 3, p. 1-23 24 p., 104013.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Downloads (Pure) -
RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo
Scherer, N., Maurel, C., Graus, M., McAlary, L., Richter, G., Radford, R. A. W., Hogan, A., Don, E. K., Lee, A., Yerbury, J., Francois, M., Chung, R. S. & Morsch, M., 22 May 2024, In: Nucleic Acids Research. 52, 9, p. 5301-5319 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Link opens in a new tab Citations (Scopus)103 Downloads (Pure) -
The Z-drugs zolpidem, zaleplon, and eszopiclone have varying actions on human GABAA receptors containing γ1, γ2, and γ3 subunits
Richter, G., Liao, V. W. Y., Ahring, P. K. & Chebib, M., 19 Nov 2020, In: Frontiers in Neuroscience. 14, p. 1-12 12 p., 599812.Research output: Contribution to journal › Article › peer-review
Open AccessFile32 Link opens in a new tab Citations (Scopus)323 Downloads (Pure)