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Research Outputs 2010 2019

  • 271 Citations
  • 6 h-Index
  • 9 Article
  • 1 Abstract
  • 1 Meeting abstract
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Article
2019

Motor neuron abnormalities correlate with impaired movement in zebrafish that express mutant superoxide dismutase 1

Robinson, K. J., Yuan, K. C., Don, E. K., Hogan, A. L., Winnick, C. G., Tym, M. C., Lucas, C. W., Shahheydari, H., Watchon, M., Blair, I. P., Atkin, J. D., Nicholson, G. A., Cole, N. J. & Laird, A. S., 1 Feb 2019, In : Zebrafish. 16, 1, p. 8-14 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Motor Neurons
Zebrafish
motor neurons
Danio rerio
superoxide dismutase
2018

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Lee, A., Rayner, S. L., Gwee, S. S. L., De Luca, A., Shahheydari, H., Sundaramoorthy, V., Ragagnin, A., Morsch, M., Radford, R., Galper, J., Freckleton, S., Shi, B., Walker, A. K., Don, E. K., Cole, N. J., Yang, S., Williams, K. L., Yerbury, J. J., Blair, I. P., Atkin, J. D. & 2 othersMolloy, M. P. & Chung, R. S., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 2, p. 335–354 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Cyclins
Ubiquitination
Autophagy
Mutation
Genes
2017

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex

Lee, A., Rayner, S. L., De Luca, A., Gwee, S. S. L., Morsch, M., Sundaramoorthy, V., Shahheydari, H., Ragagnin, A., Shi, B., Yang, S., Williams, K. L., Don, E. K., Walker, A. K., Zhang, K. Y., Yerbury, J. J., Cole, N. J., Atkin, J. D., Blair, I. P., Molloy, M. P. & Chung, R. S., 2017, In : Open Biology. 7, 10, p. 1-11 11 p., 170058.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Casein Kinase II
Phosphorylation
Cyclins
Ubiquitin-Protein Ligases
Ubiquitination

Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuum

Shahheydari, H., Ragagnin, A., Walker, A. K., Toth, R. P., Vidal, M., Jagaraj, C. J., Perri, E. R., Konopka, A., Sultana, J. M. & Atkin, J. D., 10 May 2017, In : Frontiers in Molecular Neuroscience. 10, p. 1-25 25 p., 119.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Quality Control
Proteins
Neurodegenerative Diseases
Endoplasmic Reticulum-Associated Degradation
Molecular Chaperones
2015

Preexisting MEK1(P124) Mutations Diminish Response to BRAF Inhibitors in Metastatic Melanoma Patients

Carlino, M. S., Fung, C., Shahheydari, H., Todd, J. R., Boyd, S. C., Irvine, M., Nagrial, A. M., Scolyer, R. A., Kefford, R. F., Long, G. V. & Rizos, H., 1 Jan 2015, In : Clinical Cancer Research. 21, 1, p. 98-105 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Mutation
Mitogen-Activated Protein Kinase Kinases
Disease-Free Survival
Cell Line
2014

Identification of PLP2 and RAB5C as novel TPD52 binding partners through yeast two-hybrid screening

Shahheydari, H., Frost, S., Smith, B. J., Groblewski, G. E., Chen, Y. & Byrne, J. A., 2014, In : Molecular Biology Reports. 41, 7, p. 4565-4572 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Protein Binding
Yeasts
Neoplasms
Proteins

Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

Long, G. V., Fung, C., Menzies, A. M., Pupo, G. M., Carlino, M. S., Hyman, J., Shahheydari, H., Tembe, V., Thompson, J. F., Saw, R. P., Howle, J., Hayward, N. K., Johansson, P., Scolyer, R. A., Kefford, R. F. & Rizos, H., 2014, In : Nature Communications. 5, p. 1-9 9 p., 5694.

Research output: Contribution to journalArticleResearchpeer-review

Tumors
Melanoma
therapy
mutations
Mitogen-Activated Protein Kinase Kinases
2010

Regulation of GSK-3β and β-Catenin by Gαq in HEK293T cells

Salmanian, S., Najafi, S. M. A., Rafipour, M., Arjomand, M. R., Shahheydari, H., Ansari, S., Kashkooli, L., Rasouli, S. J., Jazi, M. S. & Minaei, T., 14 May 2010, In : Biochemical and Biophysical Research Communications. 395, 4, p. 577-582 6 p.

Research output: Contribution to journalArticleResearchpeer-review

beta Catenin
Catenins
Chemical activation
Heterotrimeric GTP-Binding Proteins
Peptides

The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2

Madrid, R., Aranda, J. F., Rodríguez-Fraticelli, A. E., Ventimiglia, L., Andrés-Delgado, L., Shehata, M., Fanayan, S., Shahheydari, H., Gómez, S., Jiménez, A., Martín-Belmonte, F., Byrne, J. A. & Alonso, M. A., May 2010, In : Developmental Cell. 18, 5, p. 814-827 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Transcytosis
Actins
Association reactions
Depolymerization
Guanosine Triphosphate