Howard Gurney

Professor

  • 5481 Citations
  • 34 h-Index
1987 …2023
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Personal profile

Biography

Professor Howard Gurney is the Director of Clinical Trials for the Faculty of Medicine and Health Sciences at Macquarie University. 

Professor Gurney has a firm background in clinical research and has subspecialty interests in urogenital cancers including prostate, bladder, testis and kidney cancer. 

He has been the principal investigator for over 100 clinical trials and has published over 100 peer-reviewed articles in journals and book chapters.  Current research interests include the pharmacogenomics and therapeutic monitoring of chemotherapy and targeted therapies and he has published widely in this area.  He is regarded as a leading authority on mechanisms for safe dosing of anticancer agents and has held research grants and has written a number of invited editorials on these topics. 

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Survival Medicine & Life Sciences

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Projects 2013 2023

Research Output 1987 2018

Abiraterone alone or in combination with enzalutamide in metastatic castration-resistant prostate cancer with rising prostate-specific antigen during enzalutamide treatment

Attard, G., Borre, M., Gurney, H., Loriot, Y., Andresen-Daniil, C., Kalleda, R., Pham, T., Taplin, M. E. & on behalf of PLATO collaborators 1 Sep 2018 In : Journal of Clinical Oncology. 36, 25, p. 2639-2646 8 p.

Research output: Contribution to journalArticle

Open Access
File
Castration
Prostate-Specific Antigen
Prostatic Neoplasms
Prednisone
Control Groups

Cardiovascular toxicity of targeted therapies for cancer: a protocol for an overview of systematic reviews

Van Leeuwen, M. T., Luu, S., Gurney, H., Brown, M. R., Webber, K., Pearson, S-A., Hunt, L. & Vajdic, C. M. 1 Jun 2018 In : BMJ Open. 8, 6, p. 1-6 6 p., e021064

Research output: Contribution to journalReview article

Open Access
File
Ethics
Embolism and Thrombosis
Cerebrovascular Disorders
Neoplasms
Peer Review

Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer

Gao, B. , Lu, Y. , Nieuweboer, A. J. M. , Xu, H. , Beesley, J. , Boere, I. , De Graan, A. J. M. , De Bruijn, P. , Gurney, H. , Kennedy, C. J. , Chiew, Y. E. , Johnatty, S. E. , Beale, P. , Harrison, M. , Luccarini, C. , Conroy, D. , Mathijssen, R. H. J. , Harnett, P. R. , Balleine, R. L. , Chenevix-Trench, G. & 2 others MacGregor, S. & De Fazio, A. 1 Dec 2018 In : Scientific Reports. 8, 1, p. 1-10 10 p., 1508

Research output: Contribution to journalArticle

Open Access
File
Genome-Wide Association Study
Carboplatin
Paclitaxel
Single Nucleotide Polymorphism
Drug Therapy

Health-related quality-of-life analysis from KEYNOTE-045: a phase III study of pembrolizumab versus chemotherapy for previously treated advanced urothelial cancer

Vaughn, D. J., Bellmunt, J., Fradet, Y., Lee, J. L., Fong, L., Vogelzang, N. J., Climent, M. A., Petrylak, D. P., Choueiri, T. K., Necchi, A., Gerritsen, W., Gurney, H., Quinn, D. I., Culine, S., Sternberg, C. N., Mai, Y., Li, H., Perini, R. F., Bajorin, D. F. & de Wit, R. 1 Jun 2018 In : Journal of Clinical Oncology. 36, 16, p. 1579-1587 9 p.

Research output: Contribution to journalArticle

Quality of Life
Drug Therapy
Neoplasms
Health Status
Research Personnel

Nivolumab in the treatment of advanced renal cell carcinoma

Arasaratnam, M. & Gurney, H. Jul 2018 In : Future Oncology. 14, 17, p. 1679-1689 11 p., 29460635

Research output: Contribution to journalReview article

Renal Cell Carcinoma
Neoplasms
Interleukin-2
Therapeutics
Biomarkers