Projects per year
Personal profile
Biography
Dr. Hui Xin Ong holds a Bachelor of Pharmacy (Hons) and a PhD in Pharmaceutical Science from the University of Sydney. Her research is focused on developing pharmaceutical and medical device technologies that can be used for the treatment of respiratory and infectious diseases, and methodological platforms that can help promote the translation of new discoveries to clinical practice. Specifically, her expertise lies in the study of the dynamic interactions between the different biological barriers in the respiratory tract and aerosol particles in a representative manner which captures the true nature of aerosol interactions in the lung. Her research is currently a blend of basic, applied and clinical disciplines. Dr. Ong has worked with diverse renown experts from academia and industry partners leading to development of various state-of-the-art pharmaceutical formulations and an outstanding publication record in leading journals in the field.
Education/Academic qualification
Pharmaceuticals, PhD , University of Sydney
Award Date: 16 Oct 2013
Pharmacy, B. Pharm. (Hons), University of Sydney
Award Date: 15 Dec 2009
External positions
Research Leader , Woolcock Institute of Medical Research Limited
2020 → …
Director, Ab Initio Pharma
2019 → …
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Collaborations and top research areas from the last five years
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Development of a smart intranasal brain delivery nanogel for treatment of Alzheimer’s Disease
Traini, D., Ong, H. X., Fathi, A., Chung, R. & Wong, J.
1/09/22 → 31/01/27
Project: Research
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Monash Led: Next generation hand-held nebulisers for aerosol drug delivery: using microfluidics to tune particle size
Alan, T., Traini, D., Ong, H. X., Flynn, D., Thompson, B., Hwang, D. & Ratinac, K.
27/08/21 → 31/12/23
Project: Research
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Cause and effect: new mechanisms of particles formation in thunderstorms
Traini, D., Spicer, P., Davies, J. M., Prescott, S. & Ong, H. X.
4/11/22 → 30/06/23
Project: Research
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DIN: Unravelling the mechanisms of aerosolised toxins
Ong, H. X., Traini, D., Young, P., Cheng, S. & Spicer, P.
1/10/20 → 31/03/22
Project: Research
Research Outputs
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Advances in soft mist inhalers
Komalla, V., Wong, C. Y. J., Sibum, I., Muellinger, B., Nijdam, W., Chaugule, V., Soria, J., Ong, H. X., Buchmann, N. A. & Traini, D., 10 Jul 2023, (E-pub ahead of print) In: Expert Opinion on Drug Delivery. 16 p.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
Development of inhalable spray dried Nitrofurantoin formulations for the treatment of emphysema
Leslie, M. N., Marasini, N., Zara, S., Young, P. M., Traini, D. & Ong, H. X., Jan 2023, In: Pharmaceutics. 15, 1, p. 1-22 22 p., 146.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
Engineered dry powders for the nose-to-brain delivery of transforming growth factor-beta
Wong, C. Y. J., Baldelli, A., Gholizadeh, H., Oguzlu, H., Guo, Y., Xin Ong, H., Rodriguez, A. P., Singuera, G., Thamboo, A., Singh, A., Pratap-Singh, A. & Traini, D., Aug 2023, In: European Journal of Pharmaceutics and Biopharmaceutics. 189, p. 202-211 10 p.Research output: Contribution to journal › Article › peer-review
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In vitro and in vivo applications of a universal and synthetic thermo-responsive drug delivery hydrogel platform
Gholizadeh, H., Landh, E., Silva, D. M., Granata, A., Traini, D., Young, P., Fathi, A., Maleknia, S., Abrams, T., Dehghani, F. & Xin Ong, H., 25 Mar 2023, In: International Journal of Pharmaceutics. 635, p. 1-12 12 p., 122777.Research output: Contribution to journal › Article › peer-review
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In vitro interactions of aerosol formulations with human nasal epithelium using real-time monitoring of drug transport in a nasal mucosa-on-a-chip
Gholizadeh, H., Cheng, S., Kourmatzis, A., Traini, D., Young, P., Sheikh, Z. & Ong, H. X., 1 Mar 2023, In: Biosensors and Bioelectronics. 223, p. 1-5 5 p., 115010.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)
Prizes
Press/Media
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Fast-tracking new aerosol treatments into clinical practice
29/10/21
1 Media contribution
Press/Media: Expert Comment