Projects per year
Personal profile
Biography
Dr Ian Paulsen is Distinguished Professor at Macquarie University and Director of the ARC Centre of Excellence in Synthetic Biology (CoESB website link). He is also Deputy Director of the Macquarie Biomolecular Discovery and Design Centre. Ian is an ARC Laureate Fellow and an ISI Highly Cited Researcher. He has published more than 294 journal papers, which have received over 85,000 citations. Currently his H-index is 118 (Google Scholar, Nov 2020). Thomson Reuters identified him as one
of the world's 3000 most influential scientific minds in 2014. He was featured in The Australian as one of the top forty research superstars in Australia. Indicative of his scientific esteem, he received a Macquarie University Research Excellence Award in 2014.He received a PhD from Monash University and was an NHMRC C.J. Martin Fellow at the University of California at San Diego. He then took a faculty position at the Institute for Genomic Research (TIGR), where he led many microbial genome sequencing projects. Ian returned to Australia in 2007 as a Professor at Macquarie University and received a Life Science Research Award from the NSW Office of Science and Medical Research. He is the founder and Director of the new Synthetic Biology Laboratory at Macquarie University. His published work has received significant press attention, including two interviews on the Channel 7 news in the last two years, as well as numerous radio and newspaper interviews, including in the Washington Post and New York Times.
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Collaborations and top research areas from the last five years
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ID24 (Flinders led): The central roles of lipids in bacterial pathogenesis
Eijkelkamp, B. (Chief Investigator), Cain, A. (Primary Chief Investigator), Ponton, F. (Chief Investigator), Miller, S. (Associate Investigator), O'Mara, M. (Associate Investigator), Bihari, S. (Associate Investigator), Snel, M. (Associate Investigator) & Paulsen, I. (Associate Investigator)
1/01/25 → 31/12/27
Project: Research
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Computationally guided characterisation of MFS membrane transporters for improved functional prediction and engineering
Paulsen, I. (Primary Chief Investigator), Plisson, F. (Associate Investigator), Morton, C. (Supervisor) & Montoya-Londono, D. (PhD Student)
1/06/24 → 31/08/27
Project: Research
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IDEAS: Metformin, gut epithelium and microbiome in the prevention of colorectal cancer
Packer, N. (Primary Chief Investigator), Molloy, M. (Chief Investigator), Hewawasam Gamage, H. (Chief Investigator), Paulsen, I. (Associate Investigator), Engel, A. (Associate Investigator) & El-Omar, E. (Associate Investigator)
1/07/23 → 30/06/26
Project: Research
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Engineering Synthetic Methylotrophy in Saccharomyces cerevisiae - CSIRO Top up scholarship for Philip Kelso
Williams, T. (Primary Chief Investigator), Kelso, P. (PhD Student), Paulsen, I. (Supervisor) & Loan, T. (Supervisor)
1/06/23 → 31/05/26
Project: Research
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FAAB: ARC Training Centre for Facilitated Advancement of Australia's Bioactives (FAAB)
Rodger, A. (Primary Chief Investigator), Sunna, A. (Chief Investigator), Garcia-Bennett, A. (Chief Investigator), Guillemin, G. (Chief Investigator), Packer, N. (Chief Investigator), Thaysen-Andersen, M. (Chief Investigator), Cain, A. (Chief Investigator), Connor, M. (Chief Investigator), Haynes, P. (Chief Investigator), Paulsen, I. (Chief Investigator), Ponton, F. (Chief Investigator), Tetu, S. (Chief Investigator), Wang, Y. (Chief Investigator), Adcock, J. (Chief Investigator), Callahan, D. (Chief Investigator), Walsh, T. R. (Chief Investigator), Joyce, P. (Chief Investigator), Prestidge, C. A. (Chief Investigator), Reddy, N. (Chief Investigator), Ashton, J. (Partner Investigator), Ball, M. (Partner Investigator), Bucca, D. (Partner Investigator), de Silva, T. (Partner Investigator), Ferguson, K. (Partner Investigator), Gilbert, A. (Partner Investigator), Gilbert, E. (Partner Investigator), Hayes, E. (Partner Investigator), Mazumder, D. (Partner Investigator), Morrison, J. (Partner Investigator), Petrie, J. (Partner Investigator), Pollard, N. (Partner Investigator), Ruff, N. (Partner Investigator), Stockham, K. (Partner Investigator), Winberg, P. (Partner Investigator) & De Simone, A. (Partner Investigator)
21/02/22 → 20/02/27
Project: Research
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Building synthetic chromosomes one yeast at a time: insights from Sc2.0
Erpf, P. E., Meier, F., Walker, R. S. K., Goold, H. D., Boeke, J. D., Paulsen, I. T. & Pretorius, I. S., Dec 2025, In: Nature Biotechnology. 43, 12, p. 1911-1918 8 p.Research output: Contribution to journal › Comment/opinion › peer-review
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Characterising the multiple-plastic degrading strain of Bacillus subtilis GM_03 From the Galleria mellonella microbiome
Facey, F. S. B., Maharjan, R., Dinh, H., Buchanan, J. S., Connal, L. A., Tay, A. P., Paulsen, I. T. & Cain, A. K., Oct 2025, In: Environmental Microbiology Reports. 17, 5, p. 1-11 11 p., e70216.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome
Goold, H. D., Kroukamp, H., Erpf, P. E., Zhao, Y., Kelso, P., Calame, J., Timmins, J. J. B., Wightman, E. L. I., Peng, K., Carpenter, A. C., Llorente, B., Hawthorne, C., Clay, S., van Wyk, N., Daniel, E. L., Harrison, F., Meier, F., Willows, R. D., Cai, Y. & Walker, R. S. K. & 9 others, , 20 Jan 2025, In: Nature Communications. 16, 1, p. 1-14 14 p., 841.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)72 Downloads (Pure) -
Genetic drivers of plant root colonisation by the biocontrol agent Pseudomonas protegens Pf-5
Ghaly, T. M., Fabian, B. K., Vick, S. H. W., Foster, C., Asher, A. J., Hassan, K. A., Elbourne, L. D. H., Paulsen, I. T. & Tetu, S. G., Aug 2025, In: Environmental Microbiology Reports. 17, 4, p. 1-12 12 p., e70179.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Downloads (Pure) -
Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease
Zvyagina, V., Kuriakose, A., Simó, I., Kam, J. Y., Chakraborty, P., Robinson, K. J., Potapenko, A., Watchon, M., Paulsen, I. T., Gamage, H. K. A. H. & Laird, A. S., Nov 2025, In: Neurobiology of Disease. 216, p. 1-15 15 p., 107121.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure)
Prizes
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Funding Agreement – STEM Student Competition Sponsorship Program
Paulsen, I. (Team leader) & Harrison, F. (Recipient), 12 May 2023
Prize
File -
Macquarie University Faculty of Science and Engineering Excellence Award for Excellent Research
Li, L. (Recipient), Maharjan, R. (Recipient), Cain, A. (Recipient) & Paulsen, I. (Recipient), 2023
Prize
Press/Media
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Designer yeast just the start of a synthetic biology revolution
Paulsen, I., Johnson, D. & Kroukamp, H.
21/04/17
1 Media contribution
Press/Media: Expert Comment