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Research Outputs 2014 2019

  • 529 Citations
  • 8 h-Index
  • 12 Article
  • 4 Meeting abstract
  • 2 Review article
  • 1 Chapter
2019

Circulating cytokines predict immune-related toxicity in melanoma patients receiving anti-PD-1 based immunotherapy

Lim, S. Y., Lee, J. H., Nur Gide, T., Menzies, A. M., Guminski, A., Carlino, M. S., Breen, E., Yang, J. Y. H., Ghazanfar, S., Kefford, R. F., Scolyer, R. A., Long, G. V. & Rizos, H., Mar 2019, In : Clinical Cancer Research. 25, 5, p. 1557-1563 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Immunotherapy
Melanoma
Cytokines
Confidence Intervals
Therapeutics

Emerging novel therapies in overcoming resistance to targeted therapy

Pinho, A. V., Lee, J. H. & Rizos, H., 2019, Current applications for overcoming resistance to targeted therapies. Szewczuk, M. R., Qorri, B. & Sambi, M. (eds.). Switzerland: Springer, Springer Nature, p. 223-258 36 p. (Resistance to Targeted Anti-Cancer Therapeutics; vol. 20).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Melanoma
Neoplasms
Therapeutics
Physiologic Monitoring
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Monitoring melanoma using circulating free DNA

Diefenbach, R. J., Lee, J. H. & Rizos, H., 13 Feb 2019, In : American Journal of Clinical Dermatology. 20, 1, p. 1-12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Nucleic Acids
DNA
Polymerase Chain Reaction
Mutation

Neoadjuvant dabrafenib combined with trametinib for resectable, stage IIIB–C, BRAFV600 mutation-positive melanoma (NeoCombi): a single-arm, open-label, single-centre, phase 2 trial

Long, G. V., Saw, R. P. M., Lo, S., Nieweg, O. E., Shannon, K. F., Gonzalez, M., Guminski, A., Lee, J. H., Lee, H., Ferguson, P. M., Rawson, R. V., Wilmott, J. S., Thompson, J. F., Kefford, R. F., Ch'ng, S., Stretch, J. R., Emmett, L., Kapoor, R., Rizos, H., Spillane, A. J. & 2 othersScolyer, R. A. & Menzies, A. M., 1 Jul 2019, In : The Lancet Oncology. 20, 7, p. 961-971 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Mutation
dabrafenib
trametinib
Neoadjuvant Therapy

Pharmacokinetic and cytokine profiles of melanoma patients with dabrafenib and trametinib-induced pyrexia

Kim, H. Y., Duong, J. K., Gonzalez, M., Long, G. V., Menzies, A. M., Rizos, H., Lim, S. Y., Lee, J. & Boddy, A. V., 8 Apr 2019, In : Cancer Chemotherapy and Pharmacology. 83, 4, p. 693-704 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics
Metabolites
Melanoma
Fever
Cytokines

Pre-operative ctDNA predicts survival in high-risk stage III cutaneous melanoma patients

Lee, J. H., Saw, R. P., Thompson, J. F., Lo, S., Spillane, A. J., Shannon, K. F., Stretch, J. R., Howle, J., Menzies, A. M., Carlino, M. S., Kefford, R. F., Long, G. V., Scolyer, R. A. & Rizos, H., 1 May 2019, In : Annals of oncology : official journal of the European Society for Medical Oncology. 30, 5, p. 815-822 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Melanoma
Skin
Survival
DNA
Neoplasms
2018

Association between circulating tumor DNA and pseudoprogression in patients with metastatic melanoma treated with anti–programmed cell death 1 antibodies

Lee, J. H., Long, G. V., Menzies, A. M., Lo, S., Guminski, A., Whitbourne, K., Peranec, M., Scolyer, R., Kefford, R. F., Rizos, H. & Carlino, M. S., 1 May 2018, In : JAMA Oncology. 4, 5, p. 717-721 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Cell Death
Antibodies
DNA
Neoplasms

Evaluation of commercial kits for purification of circulating free DNA

Diefenbach, R. J., Lee, J. H., Kefford, R. F. & Rizos, H., 21 Sep 2018, In : Cancer Genetics. 228-229, p. 21-27 7 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA
Nucleic Acids
Workflow
Plasma Cells
Serum

Liquid biomarkers in melanoma: detection and discovery

Lim, S. Y., Lee, J. H., Diefenbach, R. J., Kefford, R. F. & Rizos, H., 17 Jan 2018, In : Molecular Cancer. 17, 1, p. 1-14 14 p., 8.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Melanoma
Biomarkers
Neoplasms
Tumor Biomarkers
Proteomics

Metastasis-specific patterns of response and progression with anti-PD-1 treatment in metastatic melanoma

Lee, J. H. J., Lyle, M., Menzies, A. M., Chan, M. M. K., Lo, S., Clements, A., Carlino, M. S., Kefford, R. F. & Long, G. V., 1 May 2018, In : Pigment Cell and Melanoma Research. 31, 3, p. 404-410 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Neoplasm Metastasis
Imaging techniques
Antibodies
Therapeutics
2017

Circulating tumour DNA predicts response to anti-PD1 antibodies in metastatic melanoma

Lee, J. H., Long, G. V., Boyd, S., Lo, S., Menzies, A. M., Tembe, V., Guminski, A., Jakrot, V., Scolyer, R. A., Mann, G. J., Kefford, R., Carlino, M. S. & Rizos, H., May 2017, In : Annals of Oncology. 28, 5, p. 1130-1136 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Melanoma
Antibodies
DNA
Neoplasms
Therapeutics

Evaluation of two high-throughput proteomic technologies for plasma biomarker discovery in immunotherapy-treated melanoma patients.

Lim, S. Y., Lee, J., Welsh, S. J., Ahn, S. B., Breen, E., Khan, A., Carlino, M. S., Menzies, A. M., Kefford, R. F., Scolyer, R. A., Long, G. V. & Rizos, H., 2017, In : Biomarker research. 5, p. 1-12 12 p., 32.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Biomarkers
Proteomics
Immunotherapy
Melanoma
Assays
2016

Circulating tumor DNA as a biomarker in metastatic melanoma patients treated with anti-PD1 antibodies

Lee, J., Boyd, S., Tembe, V., Menzies, A., Long, G., Guminski, A., Kefford, R., Carlino, M. & Rizos, H., 2016, In : Asia-Pacific journal of clinical oncology : special issue : implementation + innovation in immunotherapy. p. 48-49 2 p.

Research output: Contribution to journalMeeting abstractResearch

Anti-Idiotypic Antibodies
Melanoma
Biomarkers
DNA
Neoplasms

Ipilimumab therapy in patients with advanced melanoma and preexisting autoimmune disorders

Johnson, D. B., Sullivan, R. J., Ott, P. A., Carlino, M. S., Khushalani, N. I., Ye, F., Guminski, A., Puzanov, I., Lawrence, D. P., Buchbinder, E. I., Mudigonda, T., Spencer, K., Bender, C., Lee, J., Kaufman, H. L., Menzies, A. M., Hassel, J. C., Mehnert, J. M., Sosman, J. A., Long, G. V. & 1 othersClark, J. I., Feb 2016, In : JAMA Oncology. 2, 2, p. 234-240 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Preexisting Condition Coverage
Melanoma
Autoimmune Diseases
Therapeutics
Safety

PD-1 and PD-L1 inhibitors in melanoma treatment: Past success, present application and future challenges

Lee, J., Kefford, R. & Carlino, M., 1 Jun 2016, In : Immunotherapy. 8, 6, p. 733-746 14 p.

Research output: Contribution to journalReview articleResearchpeer-review

Melanoma
Critical Pathways
Standard of Care
Patient Selection
Biomarkers
2015

Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

Gray, E. S., Rizos, H., Reid, A. L., Boyd, S. C., Pereira, M. R., Lo, J., Tembe, V., Freeman, J., Lee, J. H. J., Scolyer, R. A., Siew, K., Lomma, C., Cooper, A., Khattak, M. A., Meniawy, T. M., Long, G. V., Carlino, M. S., Millward, M. & Ziman, M., 2015, In : Oncotarget. 6, 39, p. 42008-42018 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Melanoma
DNA
Neoplasms
Therapeutics
Immunotherapy

Patterns of acquired resistance to anti-PD-1 antibodies in patients with metastatic melanoma (MM)

Lee, J. H. J., Cooper, A. J., Lyle, M. K., Liniker, E., Menzies, A. M., Kefford, R., Long, G. V. & Carlino, M. S., 20 May 2015, In : Journal of Clinical Oncology. 33, 15 supplement, p. e20005 1 p.

Research output: Contribution to journalMeeting abstractResearch

2014

Lesion-specific patterns of response and progression with anti-PD-1 treatment in metastatic melanoma (MM)

Lyle, M. K., Lee, J. HJ., Menzies, A. M., Chan, M. M. K., Clements, A., Carlino, M. S., Kefford, R. & Long, G. V., 20 May 2014, In : Journal of Clinical Oncology. 32, 15_suppl, p. 1-1 1 p., 9077.

Research output: Contribution to journalMeeting abstractResearch

Lesion-specific patterns of response and progression with anti-PD-1 treatment in metastatic melanoma (MM)

Lyle, M., Lee, J., Menzies, A. M., Chan, M. M. K., Clements, A., Carlino, M. S., Kefford, R. & Long, G. V., 2014, In : Asia-Pacific Journal of Clinical Oncology. 10, Supplement 6, p. 63-63 1 p.

Research output: Contribution to journalMeeting abstractResearch