• 917 Citations
  • 17 h-Index
19992019
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Personal profile

Research interests

My research is focussed on the discovery and biosynthesis of natural products or specialised metabolites from various sources, predominantly bacteria and fungi. Although their roles in nature are not always clear, many of these metabolites possess properties which make them suitable candidates for downstream development by the biotech, pharmaceutical, agricultural, water management and food industries. The broad aims of such research are to generate large numbers of natural products with diverse structures and activities for screening, better understand their biosynthesis at the genetics level, and generate greater molecular diversity using genetic techniques.

Biography

Qualifications

B.App.Sci. (Hons) W. Sydney, Ph.D Griffith, MRACI CChem

Employment

2018-               Research Fellow, Macquarie University

2018-               Snr Research Scientist, Microbial Screening Technologies, Sydney

2017-2017       Research Assistant, Western Sydney University

2016-2017       Research Associate, Fukui Prefectural University, Japan

2007-2017       Research Associate, University of New South Wales

2015-2016       Visiting Scientist, Fukui Prefectural University, Japan

2006-2007       Research Associate, Scripps Inst. of Oceanography, UCSD, USA

2004-2005       Research Assistant, University of Melbourne

2001-2004       Research Intern, University of Arizona, USA

Education/Academic qualification

Marine Natural Products, Ph.D, Griffith University

Applied Chemistry, B. App. Sci. (Hons), Univ of Western Sydney Nepean

External positions

Senior Research Scientist, Microbial Screening Technologies Pty Ltd

8 Jan 2018 → …

Fingerprint Dive into the research topics where John Kalaitzis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Polyketides Medicine & Life Sciences
Biosynthesis Chemical Compounds
Biological Products Medicine & Life Sciences
Polyketide Synthases Medicine & Life Sciences
Biosynthetic Pathways Medicine & Life Sciences
Genes Chemical Compounds
Porifera Medicine & Life Sciences
Metabolites Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Outputs 1999 2019

Harnessing long-read amplicon sequencing to uncover NRPS and Type I PKS gene sequence diversity in polar desert soils

Benaud, N., Zhang, E., van Dorst, J., Brown, M. V., Kalaitzis, J. A., Neilan, B. A. & Ferrari, B. C., Apr 2019, In : FEMS Microbiology Ecology. 95, 4, 12 p., fiz031.

Research output: Contribution to journalArticleResearchpeer-review

Polyketides
desert soil
peptide
Soil
Biological Products

Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis

Lacey, H. J., Gilchrist, C. L. M., Crombie, A., Kalaitzis, J. A., Vuong, D., Rutledge, P. J., Turner, P., Pitt, J. I., Lacey, E., Chooi, Y-H. & Piggott, A. M., 5 Nov 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 2631-2643 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
Aspergillus
Metabolites
Fungi
Spectroscopic analysis
Bioinformatics

Combined genetic and bioactivity-based prioritization leads to the isolation of an endophyte-derived antimycobacterial compound

Alvin, A., Kalaitzis, J. A., Sasia, B. & Neilan, B. A., May 2016, In : Journal of Applied Microbiology. 120, 5, p. 1229-1239 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Endophytes
Peptide Synthases
Polyketide Synthases
Polyketides
Fusarium

Genome-guided discovery of natural products and biosynthetic pathways from Australia's untapped microbial megadiversity

Kalaitzis, J. A., Ingrey, S. D., Chau, R., Simon, Y. & Neilan, B. A., 2016, In : Australian Journal of Chemistry. 69, 2, p. 129-135 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Biosynthesis
Biological Products
Genes
DNA sequences
Isotopes

Nonribosomal peptide synthase gene as an indicator for peptide antibiotics production in PNG'S marine microbial communities

Noro, J., Kalaitzis, J., Matainaho, T. & Neilan, B., 2015, Promoting responsible sustainable development through science & technology, the PNG way. Temple, V., Mowbray, D., Rai, P. P., Gideon, O., Kaluwin, C. & Watmelik, J. (eds.). Papua New Guinea: University of Papua New Guinea, Vol. 1. p. 1-18 18 p.

Research output: Chapter in Book/Report/Conference proceedingConference proceeding contributionResearchpeer-review