Personal profile
Research interests
My research is focussed on the discovery and biosynthesis of natural products or specialised metabolites from various sources, predominantly bacteria and fungi. Although their roles in nature are not always clear, many of these metabolites possess properties which make them suitable candidates for downstream development by the biotech, pharmaceutical, agricultural, water management and food industries. The broad aims of such research are to generate large numbers of natural products with diverse structures and activities for screening, better understand their biosynthesis at the genetics level, and generate greater molecular diversity using genetic techniques.
Biography
Qualifications
B.App.Sci. (Hons) W. Sydney, Ph.D Griffith, MRACI CChem
Employment
2018- Research Fellow, Macquarie University
2018-2021 Snr Res Scientist, Microbial Screening Technologies, Sydney
2017-2017 Research Assistant, Western Sydney University
2016-2017 Research Associate, Fukui Prefectural University, Japan
2007-2017 Research Associate, University of New South Wales
2015-2016 Visiting Scientist, Fukui Prefectural University, Japan
2006-2007 Research Associate, Scripps Inst. of Oceanography, UCSD, USA
2004-2005 Research Assistant, University of Melbourne
2001-2004 Research Intern, University of Arizona, USA
Education/Academic qualification
Marine Natural Products, Ph.D, Chemical Investigations of Australian Marine Sponges, Griffith University
Applied Chemistry, B. App. Sci. (Hons), Univ of Western Sydney Nepean
External positions
Senior Research Scientist, Microbial Screening Technologies Pty. Ltd.
8 Jan 2018 → Oct 2021
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Geministatins: new depside antibiotics from the fungus Austroacremonium gemini
Crombie, A., Kalaitzis, J. A., Chen, R., Vuong, D., Lacey, A. E., Lacey, E., Shivas, R. G., Tan, Y. P., Sbaraini, N., Chooi, Y. H. & Piggott, A. M., Oct 2024, In: Journal of Antibiotics. 77, 10, p. 639-646 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)42 Downloads (Pure) -
Heterologous biosynthesis of the sterol O-acyltransferase inhibitor helvamide unveils an α-ketoglutarate-dependent cross-linking oxygenase
Wang, R., Liang, J. J., Yang, W., Vuong, D., Kalaitzis, J. A., Lacey, A. E., Lacey, E., Piggott, A. M., Chooi, Y. H. & Li, H., 8 Mar 2024, In: Organic Letters. 26, 9, p. 1807-1812 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)90 Downloads (Pure) -
Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594
Lacey, A. E., Minns, S. A., Chen, R., Vuong, D., Lacey, E., Kalaitzis, J. A., Tan, Y. P., Shivas, R. G., Butler, M. S. & Piggott, A. M., Mar 2024, In: Journal of Antibiotics. 77, 3, p. 147–155 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)131 Downloads (Pure) -
The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains
Sbaraini, N., Crombie, A., Kalaitzis, J. A., Vuong, D., Bracegirdle, J., Windsor, F., Lau, A., Chen, R., Tan, Y. P., Lacey, A., Lacey, E., Piggott, A. M. & Chooi, Y. H., 7 Dec 2024, In: Chemical Science. 15, 45, p. 18872-18880 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Link opens in a new tab Citations (Scopus)42 Downloads (Pure) -
Fuligopyrones from the fruiting bodies of myxomycete Fuligo septica offer short-term protection from abiotic stress induced by UV radiation
Minns, S. A., Bowles, S., Lacey, E., Kalaitzis, J. A., Vuong, D., Butler, M. S. & Piggott, A. M., 24 Mar 2023, In: Journal of Natural Products. 86, 3, p. 633-637 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)92 Downloads (Pure)