Projects per year
Search results
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Active
C4201002: CTU: A PHASE 1, OPEN-LABEL, MULTI-CENTER, DOSE-FINDING, PHARMACOKINETIC, SAFETY AND TOLERABILITY STUDY OF PF-07265807 IN PARTICIPANTS WITH SELECTED ADVANCED OR METASTATIC SOLID TUMOR MALIGNANCIES
Park, J., Chester, C. & Chapman, N.
18/09/22 → 31/03/27
Project: Research
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D3S-001-100: CTU: A Phase 1, Open Label, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of D3S 001 Monotherapy in Subjects with Advanced Solid Tumors with a KRAS p.G12C Mutation
Park, J., Chester, C. & Chapman, N.
24/08/22 → 13/07/27
Project: Research
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BAT-7104-002-CR: CTU: A Phase 1, Multi-Center, Open-Label Study to Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BAT7104 in Patients with Advanced Solid Tumours
Park, J., Chester, C. & Chapman, N.
23/06/22 → 30/03/27
Project: Research
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VT3996-301: CTU: An Open-Label, Multicenter Phase 1b/2 Study of Nanatinostat and Valganciclovir in Patients with Advanced Epstein-Barr Virus-Positive (EBV+) Solid Tumors and in Combination with Pembrolizumab in Patients with Recurrent/Metastatic Nasopharyngeal Carcinoma
Park, J., Chapman, N. & Chester, C.
21/06/22 → 27/04/27
Project: Research
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ADG126-1001: CTU: A First-in-Human (FIH), Open-Label, Phase I Dose Escalation and Expansion Study of ADG126, ADG126 in Combination with Toripalimab, and ADG126 in Combination with ADG106 in Patients with Advanced/Metastatic Solid Tumors
Park, J., Chapman, N. & Chester, C.
25/05/22 → 26/05/27
Project: Research
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MT-5111_001: A Phase 1b Open-label, Multicenter Dose Escalation and Expansion Study of MT-5111 in Subjects With Previously Treated Advanced HER2-positive Solid Tumors
Sabanathan, D., Park, J. & Chapman, N.
13/12/21 → 12/12/26
Project: Research
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TACTI-003: TACTI-003 (Two ACTive Immunotherapeutics): A multicenter, open label, randomized, Phase II trial to investigate a soluble LAG-3 fusion protein, eftilagimod alpha (efti; IMP321) in combination with pembrolizumab (PD-1 antagonist) for first line treatment of subjects with unresectable recurrent or metastatic squamous cell carcinoma of the head and neck (HNSCC)
Park, J. & Chapman, N.
1/11/21 → 1/10/26
Project: Research
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GS-US-548-5916: A Phase 2 Study of Magrolimab Combination Therapy in Patients with Head and Neck Squamous Cell Carcinoma
Park, J., Sabanathan, D., Xia, C. Y., Kim, S. & Chapman, N.
3/08/21 → 29/07/26
Project: Research
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ACT16849: A Phase 2 non-randomized, open-label, multi-cohort, multi-center study assessing the clinical benefit of SAR444245 (THOR-707) combined with other anticancer therapies for the treatment of participants with lung cancer or pleural mesothelioma
Park, J., Chapman, N. & Tan, P.
13/05/21 → 15/04/26
Project: Research
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CS3002-101: A phase 1, open-label, multi-dose, dose escalation and expansion study to investigate the safety, tolerability, pharmacokinetics and anti-tumor activities of CS3002, a CDK4/6 inhibitor, in subjects with advance solid tumors
Park, J., Sabanathan, D. & Chapman, N.
30/10/20 → 24/09/25
Project: Research
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EFC15935: A randomized, multicentre, double-blind phase 3 study of SAR439859 plus palbociclib versus letrozole plus palbociclib for the treatment of patients with ER (+), HER2 (-) breast cancer who have not received prior systemic anti-cancer treatment for advanced disease
Sabanathan, D., Park, J. & Chapman, N.
30/09/20 → 30/09/25
Project: Research
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ADG116-1003: A Phase 1, Open-Label, Dose Escalation Study of ADG116 in Patients with Advanced/Metastatic Solid Tumors
Park, J., Chapman, N. & Sabanathan, D.
14/09/20 → 27/08/25
Project: Research
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SBT6050-1001: A Phase 1/1b, Open Label, Dose Escalation and Expansion Study of SBT6050 in Patients with Advanced Solid Tumors Expressing HER2
Sabanathan, D., Park, J. & Chapman, N.
2/09/20 → 27/08/25
Project: Research
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XL184-021: A Phase 1b Dose-Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination with Atezolizumab to Subjects with Locally Advanced or Metastatic Solid Tumors
Park, J., Sabanathan, D., Gurney, H., Chapman, N. & Rai, M.
28/08/20 → 30/04/25
Project: Research
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CN1-101: A phase I, open label, multi-center,dose escalation clinical study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma
Park, J., Chapman, N., Gurney, H. & Sabanathan, D.
3/08/20 → 30/06/25
Project: Research
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IMU.201.101: An open label, multi-centre, dose escalation/expansion, phase1 study of IMU-201 (PD1-Vazz) a B-cell immunotherapy in adults with non-small cell lung cancer
Park, J. & Chapman, N.
1/08/20 → 30/06/25
Project: Research
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Y-biologics: A Phase 1, Open-Label, Multicenter, Single Arm, Dose-Escalation/Dose-Expansion Study of YBL-006 in Patients with Advanced Solid Tumors
Sabanathan, D., Park, J., Gurney, H., Chapman, N. & Rai, M.
1/06/20 → 30/04/23
Project: Research