Projects per year
Personal profile
Biography
Julie is interested in the basic cellular and molecular singalling mechanisms involved in neurons as well as other cells. She is particularly interested in processes that trigger neurodegeneration in amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND), and related condition frontotemporal dementia (FTD). This includes the role of cellular trafficking and the DNA damage response, as well as the protein disulphide isomerase family of chaperones.
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Collaborations and top research areas from the last five years
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MNDRA24: Examining the Pathogenic Roles of Circular RNAs in Genomic Instability in ALS
1/06/24 → 31/05/25
Project: Research
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Quinolinones as a Novel Therapeutic Strategy in ALS
Atkin, J., Abbott, B. M. & Laird, A.
1/09/22 → 31/08/25
Project: Research
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Characterising the unique functional and pathological properties of a novel extracellular RNA binding protein in Amyotrophic Lateral Sclerosis
Atkin, J., Patani , R. & Ule, J.
1/01/22 → 31/12/26
Project: Research
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C9orf72-associated dipeptide repeat expansions perturb ER-golgi vesicular trafficking, inducing golgi fragmentation and ER stress, in ALS/FTD
Sultana, J., Ragagnin, A. M. G., Parakh, S., Saravanabavan, S., Soo, K. Y., Vidal, M., Jagaraj, C. J., Ding, K., Wu, S., Shadfar, S., Don, E. K., Deva, A., Nicholson, G., Rowe, D. B., Blair, I., Yang, S. & Atkin, J. D., 9 May 2024, (E-pub ahead of print) In: Molecular Neurobiology. 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular hallmarks of ageing in amyotrophic lateral sclerosis
Jagaraj, C. J., Shadfar, S., Kashani, S. A., Saravanabavan, S., Farzana, F. & Atkin, J. D., 2 Mar 2024, In: Cellular and Molecular Life Sciences. 81, 1, p. 1-30 30 p., 111.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2 Citations (Scopus)58 Downloads (Pure) -
Protein disulfide isomerase endoplasmic reticulum protein 57 (ERp57) is protective against ALS-associated mutant TDP-43 in neuronal cells
Parakh, S., Perri, E. R., Vidal, M., Takalloo, Z., Jagaraj, C. J., Mehta, P., Yang, S., Thomas, C. J., Blair, I. P., Hong, Y. & Atkin, J. D., Dec 2024, In: NeuroMolecular Medicine. 26, 1, p. 1-15 15 p., 23.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure) -
ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation
Ragagnin, A. M. G., Sundaramoorthy, V., Farzana, F., Gautam, S., Saravanabavan, S., Takalloo, Z., Mehta, P., Do-Ha, D., Parakh, S., Shadfar, S., Hunter, J., Vidal, M., Jagaraj, C. J., Brocardo, M., Konopka, A., Yang, S., Rayner, S. L., Williams, K. L., Blair, I. P., Chung, R. S., & 3 others, 22 Nov 2023, In: Scientific Reports. 13, 1, p. 1-20 20 p., 20467.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)51 Downloads (Pure) -
Dysregulated actin dynamics and cofilin correlate with TDP-43 pathology in sporadic amyotrophic lateral sclerosis
Jagaraj, C. J., Mehta, P., Parakh, S., Shadfar, S., Jamali, M. S., Suchowerska, A. K., Sultana, J., Fath, T. & Atkin, J. D., 29 Aug 2023, (Submitted) 41 p. (bioRxiv).Research output: Working paper › Preprint