Projects per year
Personal profile
Biography
Julie is interested in the basic cellular and molecular singalling mechanisms involved in neurons as well as other cells. She is particularly interested in processes that trigger neurodegeneration in amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND), and related condition frontotemporal dementia (FTD). This includes the role of cellular trafficking and the DNA damage response, as well as the protein disulphide isomerase family of chaperones.
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Collaborations and top research areas from the last five years
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Quinolinones as a Novel Therapeutic Strategy in ALS
Atkin, J., Abbott, B. M. & Laird, A.
1/09/22 → 31/08/25
Project: Research
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Characterising the unique functional and pathological properties of a novel extracellular RNA binding protein in Amyotrophic Lateral Sclerosis
Atkin, J., Patani , R. & Ule, J.
1/01/22 → 31/12/26
Project: Research
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Modulating actin dynamics in ALS/MND as a novel therapeutic approach
Atkin, J., Woodruff, T. M., Karl, T., Craik, D., Guillemin, G. & Laird, A.
4/01/21 → 3/01/24
Project: Research
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ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation
Ragagnin, A. M. G., Sundaramoorthy, V., Farzana, F., Gautam, S., Saravanabavan, S., Takalloo, Z., Mehta, P., Do-Ha, D., Parakh, S., Shadfar, S., Hunter, J., Vidal, M., Jagaraj, C. J., Brocardo, M., Konopka, A., Yang, S., Rayner, S. L., Williams, K. L., Blair, I. P., Chung, R. S., & 3 others , 22 Nov 2023, In: Scientific Reports. 13, 1, p. 1-20 20 p., 20467.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Downloads (Pure) -
Redox dysregulation as a driver for DNA damage and its relationship to neurodegenerative diseases
Shadfar, S., Parakh, S., Jamali, M. S. & Atkin, J., 14 Apr 2023, In: Translational Neurodegeneration. 12, 1, p. 1-34 34 p., 18.Research output: Contribution to journal › Review article › peer-review
Open AccessFile4 Citations (Scopus)7 Downloads (Pure) -
DNA damage, defective DNA repair, and neurodegeneration in amyotrophic lateral sclerosis
Konopka, A. & Atkin, J. D., 27 Apr 2022, In: Frontiers in Aging Neuroscience. 14, p. 1-15 15 p., 786420.Research output: Contribution to journal › Review article › peer-review
Open AccessFile10 Citations (Scopus)22 Downloads (Pure) -
Editorial: Defective DNA damage response: Repair axis in post-mitotic neurons in human health and neurodegenerative diseases
Konopka, A., Atkin, J. & Mitra, J., 23 Aug 2022, In: Frontiers in Cellular Neuroscience. 16, p. 01-02 2 p., 1009760.Research output: Contribution to journal › Editorial › peer-review
Open AccessFile20 Downloads (Pure) -
TDP-43 is a ubiquitylation substrate of the SCFcyclin F complex
Rayner, S. L., Yang, S., Farrawell, N. E., Jagaraj, C. J., Cheng, F., Davidson, J. M., Luu, L., Redondo, A. G., Rábano, A., Borrego-Hernández, D., Atkin, J. D., Morsch, M., Blair, I. P., Yerbury, J. J., Chung, R. & Lee, A., 1 Jun 2022, In: Neurobiology of Disease. 167, p. 1-11 11 p., 105673.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)40 Downloads (Pure)