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Research Outputs 1993 2020

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Review article
2019

Motor neuron susceptibility in ALS/FTD

Ragagnin, A. M. G., Shadfar, S., Vidal, M., Jamali, M. S. & Atkin, J. D., 27 Jun 2019, In : Frontiers in Neuroscience. 13, JUN, p. 1-37 37 p., 532.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Amyotrophic Lateral Sclerosis
Motor Neurons
Intrinsic Factor
Neurodegenerative Diseases
Brain Stem
2018

Dysfunction of optineurin in amyotrophic lateral sclerosis and glaucoma

Toth, R. P. & Atkin, J. D., 23 May 2018, In : Frontiers in Immunology. 9, p. 1-19 19 p., 1017.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Amyotrophic Lateral Sclerosis
Glaucoma
Autophagy
Neurodegenerative Diseases
Mutation

Rab-dependent cellular trafficking and amyotrophic lateral sclerosis

Parakh, S., Perri, E. R., Jagaraj, C. J., Ragagnin, A. M. G. & Atkin, J. D., 2 Nov 2018, In : Critical Reviews in Biochemistry and Molecular Biology. 53, 6, p. 623-651 29 p.

Research output: Contribution to journalReview articleResearchpeer-review

rab GTP-Binding Proteins
Amyotrophic Lateral Sclerosis
Neurons
Defects
Intracellular Membranes

The emerging role of DNA damage in the pathogenesis of the C9Orf72 repeat expansion in amyotrophic lateral sclerosis

Konopka, A. & Atkin, J. D., 12 Oct 2018, In : International Journal of Molecular Sciences. 19, 10, p. 1-21 21 p., 3137.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
pathogenesis
Chromosomes, Human, Pair 9
chromosomes
Amyotrophic Lateral Sclerosis
Chromosomes
2017

Protein Disulphide Isomerases: emerging roles of PDI and ERp57 in the nervous system and as therapeutic targets for ALS

Perri, E., Parakh, S. & Atkin, J., 2 Jan 2017, In : Expert Opinion on Therapeutic Targets. 21, 1, p. 37-49 13 p.

Research output: Contribution to journalReview articleResearchpeer-review

Protein Disulfide-Isomerases
Amyotrophic Lateral Sclerosis
Neurology
Endoplasmic Reticulum
Nervous System
2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., Airoldi, E. M. & 224 othersAit-Si-Ali, S., Akematsu, T., Akporiaye, E. T., Al-Rubeai, M., Albaiceta, G. M., Albanese, C., Albani, D., Albert, M. L., Aldudo, J., Algül, H., Alirezaei, M., Alloza, I., Almasan, A., Almonte-Beceril, M., Alnemri, E. S., Alonso, C., Altan-Bonnet, N., Altieri, D. C., Alvarez, S., Alvarez-Erviti, L., Alves, S., Amadoro, G., Amano, A., Amantini, C., Ambrosio, S., Amelio, I., Amer, A. O., Amessou, M., Amon, A., An, Z., Anania, F. A., Andersen, S. U., Andley, U. P., Andreadi, C. K., Andrieu-Abadie, N., Anel, A., Ann, D. K., Anoopkumar-Dukie, S., Antonioli, M., Aoki, H., Apostolova, N., Aquila, S., Aquilano, K., Araki, K., Arama, E., Aranda, A., Araya, J., Arcaro, A., Arias, E., Arimoto, H., Ariosa, A. R., Armstrong, J. L., Arnould, T., Arsov, I., Asanuma, K., Askanas, V., Asselin, E., Atarashi, R., Atherton, S. S., Atkin, J. D., Attardi, L. D., Auberger, P., Auburger, G., Aurelian, L., Autelli, R., Avagliano, L., Avantaggiati, M. L., Avrahami, L., Azad, N., Awale, S., Bachetti, T., Backer, J. M., Bae, D. H., Bae, J. S., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, S. H., Baghdiguian, S., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X. Y., Bailly, Y., Balaji, K. N., Balduini, W., Ballabio, A., Balzan, R., Banerjee, R., Bánhegyi, G., Bao, H., Barbeau, B., Barrachina, M. D., Barreiro, E., Bartel, B., Bartolomé, A., Bassham, D. C., Bassi, M. T., Bast, R. C., Basu, A., Batista, M. T., Batoko, H., Battino, M., Bauckman, K., Baumgarner, B. L., Bayer, K. U., Beale, R., Beaulieu, J. F., Beck, G. R., Becker, C., Beckham, J. D., Bédard, P. A., Burke, R. E., Campbell, M., Chen, M., Chen, Q., Chen, W., Chen, W-J., Chen, W. Q., Chen, Y., Chen, Z., Chen, Z., Clarke, P. G. H., Dickson, R. C., Dong, Z., Du, L-L., Evans, T. J., Fan, J., Fisher, P. B., Gao, F., Han, F., Harris, J., He, R. R., Hoppe, T., Huang, K. H., Huang, W. P., Huang, Y-R., Jackson, W. T., Johnson, D. E., Jones, C., Karim, M. R., Kim, E. K., Kim, J. S., Kim, J. C., Kim, Y. S., Lee, J. K., Lee, J. H., Lee, M., Lee, S-J., Lee, S. Y., Lee, S. J., Lee, Y. H., Li, C., Li, F. J., Li, J., Li, M., Li, Q., Li, W., Lin, W. W., Liu, F., Liu, J. J., Liu, R. Y., Liu, W., Mihailidou, A. S., Mitchell, C. H., Moore, M. N., Morgan, M. J., Murray, J. T., Rimbach, G., Song, W., Sue, C. M., Sun, Y., Sun, Y., Sundaramoorthy, V., Sweeney, S. T., Taylor, G. S., Taylor, G. A., Taylor, M. J., Wang, B., Wang, J., Wang, M., Wang, M-Q., Wang, P. Y., Wang, S., Wang, T. F., Wang, X., Wang, X-W., Wang, X., Wang, Y., Wang, Y., Wang, Y-J., Wang, Y., Wang, Y. T., Wang, Y., White, A. R., Williams, K., Williamson, P. R., Wolvetang, E. J., Wong, R. W., Wong, V. K. W., Woodcock, E. A., Xu, F., Xu, J., Yang, J. M., Yang, Q., Yang, W. Y., Yang, Y., Yang, Y., Yu, X-F., Zhang, F., Zhang, H., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, Y., Zhao, M., Zhao, W-L., Zhao, Y. G., Zhao, Z., Zheng, X-L. & Zhu, X-F., 21 Jan 2016, In : Autophagy. 12, 1, p. 1-222 222 p.

Research output: Contribution to journalReview articleResearchpeer-review

Protein folding alterations in amyotrophic lateral sclerosis

Parakh, S. & Atkin, J. D., 1 Oct 2016, In : Brain Research. 1648, p. 633-649 17 p.

Research output: Contribution to journalReview articleResearchpeer-review

Protein Folding
Amyotrophic Lateral Sclerosis
Proteins
Neurodegenerative Diseases
Protein Disulfide-Isomerases
2015

Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences

Sundaramoorthy, V., Sultana, J. M. & Atkin, J. D., 2015, In : Frontiers in Neuroscience. 9, p. 1-11 11 p., 400.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Amyotrophic Lateral Sclerosis
Autophagy
Golgi Apparatus
Motor Neurons
Animal Disease Models
2013

Redox regulation in amyotrophic lateral sclerosis

Parakh, S., Spencer, D. M., Halloran, M. A., Soo, K. Y. & Atkin, J. D., 2013, In : Oxidative Medicine and Cellular Longevity. 2013, p. 1-12 12 p., 408681.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Amyotrophic Lateral Sclerosis
Oxidation-Reduction
Protein Disulfide-Isomerases
Motor Neurons
Oxidation

The role of S-nitrosylation and S-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration

Halloran, M., Parakh, S. & Atkin, J. D., 2013, In : International Journal of Cell Biology. 2013, p. 1-15 15 p., 797914.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Protein Disulfide-Isomerases
Neurodegenerative Diseases
Proteins
Endoplasmic Reticulum Stress
Molecular Chaperones
2011

Mechanisms of neuroprotection by protein disulphide isomerase in amyotrophic lateral sclerosis

Walker, A. K. & Atkin, J. D., Feb 2011, In : Neurology Research International. 2011, p. 1-7 7 p., 317340.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Protein Disulfide-Isomerases
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum Stress
Genetic Models
Motor Neurons

Molecular motor proteins and amyotrophic lateral sclerosis

Soo, K. Y., Farg, M. & Atkin, J. D., Dec 2011, In : International Journal of Molecular Sciences. 12, 12, p. 9057-9082 26 p.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
File
Molecular Motor Proteins
Dyneins
Amyotrophic Lateral Sclerosis
Neurons
Motor Neurons

Stress signaling from the endoplasmic reticulum: A central player in the pathogenesis of amyotrophic lateral sclerosis

Walker, A. K. & Atkin, J. D., Sep 2011, In : IUBMB Life. 63, 9, p. 754-763 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Endoplasmic Reticulum Stress
Amyotrophic Lateral Sclerosis
Unfolded Protein Response
Proteins
Endoplasmic Reticulum
2010

Multifaceted deaths orchestrated by mitochondria in neurones

Nagley, P., Higgins, G. C., Atkin, J. D. & Beart, P. M., Jan 2010, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1802, 1, p. 167-185 19 p.

Research output: Contribution to journalReview articleResearchpeer-review

Mitochondria
Neurons
Cell Death
Necrosis
Apoptosis
2006

ER stress and UPR in familial amyotrophic lateral sclerosis

Turner, B. J. & Atkin, J. D., Feb 2006, In : Current Molecular Medicine. 6, 1, p. 79-86 8 p.

Research output: Contribution to journalReview articleResearchpeer-review

Unfolded Protein Response
Endoplasmic Reticulum Stress
Heat-Shock Proteins
Endoplasmic Reticulum
Proteins